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| 1 | 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents显示文摘Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up. | Cheng Wang Yaqi Li Ying Liao Hong Tian Min Huang Xiangyu Dong Lin Shi Jinghui Sun Hongfang Jin Junbao Du Jindou An Jie Chen Mingwu Chen Qi Chen Sun Chen Yonghong Chen Zhi Chen Adolphus Kai-tung Chau Junbao Du Zhongdong Du Junkai Duan Hongyu Duan Xiangyu Dong Lin Feng Lijun Fu Fangqi Gong Yonghao Gui Ling Han Zhenhui Han Bing He Zhixu He Xiufen Hu Yimin Hua Guoying Huang Min Huang Ping Huang Yujuan Huang Hongfang Jin Mei Jin Bo Li Fen Li Tao Li Xiaohui Li Xiaoyan Liu Yan Li Haitao Lv Tiewei Lv Zipu Li Luyi Ma Silin Pan Yusheng Pang Hua Peng Yuming Qin Jie Shen Lin Shi Kun Sun Jinghui Sun Hong Tian Jie Tian Cheng Wang Hong Wang Lei Wang Jinju Wang Wendi Wang Yuli Wang Rongzhou Wu Tianhe Xia Yanyan Xiao Chunhong Xie Yanlin Xing Zhenyu Xiong Baoyuan Xu Yi Xu Hui Yan Shiwei Yang Qijian Yi Xia Yu Xianyi Yu Yue Yuan Hongyan Zhang Huili Zhang Li Zhang Qingyou Zhang Xi Zhang Yanmin Zhang Zhiwei Zhang Cuifen Zhao Bin Zhou Hua Zhu | 2018 | Science Bulletin2018，63，23： | 54 |
| 2 | Clinical significance of gastrostomy for patients injury percutaneous endoscopic with severe craniocerebral显示文摘 | Tian Yong Du Hanggen Fan Chengpu Wang Cheng Zhang Guojun Chen Li Li Hongyu | 2014 | Chinese Journal of Traumatology2014，17，6： | 18 |
| 3 | Research Progress in the Application of Chinese Herbal Medicines in Aquaculture: A Review显示文摘 | Hongyu Pu Xiaoyu Li Qingbo Du Hao Cui Yongping Xu | 2017 | Engineering2017，3，5： | 17 |
| 4 | Low-mature gases and typical low-mature gas fields in China显示文摘No natural gas pool of industrial importance could be formed at the low-evolution stage of organic matter. In the 1980s, on the basis of the development in exploration practice, the hypotheses of bio-thermo-catalytic transitional zone gases and early thermogenic gases were proposed. The lower-limit Ro values for the formation and accumulation of natural gases of industrial importance have been expanded to 0.3%―0.4%. In the light of the two-stage model established on the basis of carbon isotope fractionation in coal-type natural gases, the upper-limit Ro values have been set at 0.8%―1.0%. In terms of the geological practice in the low-mature gas zones and China's main coal-type gas fields, it is feasible and proper to set the upper-limit Ro value of low-mature gases at 0.8%. Supper-large gas fields such as the Urengoy gas field in western Siberian Basin should belong to low-mature gas fields, of which the natural gas reserves account for more than 20% of the global proven reserves, providing strong evidence for the significance of such a type of resources. The proven natural gas reserves in the Turpan-Hami Basin of China have almost reached 1000 × 108 m3. The main source rocks in this area are the Jurassic Xishanyao Formation, which occurs as a suite of coal series strata. The corresponding thermal evolution indices (Ro ) are mainly within the range of about 0.4%―0.8%, the δ 13C1 values of methane vary between-44‰ and-39‰ (correspondingly Ro =0.6%―0.8%), and those of ethane are within the range of-29‰―-26‰, indicating that natural gases in the Turpan-Hami Basin should be designated to coal-type low-mature gases. The light hydrocarbon evolution indices of natural gases also fall within the area of low evolution while the precursor type of light hydrocarbons also shows the characteristics of the coal-type. The geological background, carbon isotopic composition and light hydrocarbon index all provide strong evidence suggesting that the proven natural gases in the Turpan-Hami Basin are low-mature gases. In China a gas field with the gas reserves reaching 300 ×108 m3 can be defined as a large gas field, and thus the proven low-mature gases in the Turpan-Hami Basin are equivalent to the reserves of three large gas fields. Its existence is of great significance in research on and exploration of low-mature gases in China. | XU YongChang WANG ZhiYong WANG XiaoFeng ZHENG JianJing DU HongYu | 2008 | Science China Earth Sciences2008，51，2： | 11 |
| 5 | The Cambrian sedimentary characteristics and their implications for oil and gas exploration in north margin of Middle-Upper Yangtze Plate显示文摘Using data from tens of measured and observed outcrop successions,thin rock slices and sample analyses,we comprehensively studied the Cambrian sedimentary environments and evolutionary characteristics in the north margin of the Middle-Upper Yangtze Plate.During the Cambrian,platform,slope,and deep sea basin environments were developed in the study area.On the platform,both clastic rocks and carbonate rocks were deposited.Clastic rocks mainly occur in the Lower Cambrian,and were deposited in marine shore and shelf environments.Carbonate rocks are dominant in the Middle and Upper Cambrian,and were deposited in the open platform,restricted platform,tidal flat,beach,and reef environments.Carbonate gravity flow deposits were developed on the slope.In the basin,mainly black shales and chert beds were deposited.The Cambrian represents one large transgression-regression cycle,and maximum transgression occurred in the Qiongzhusi Age of the Early Cambrian.Tectonics and sea level fluctuations had important impacts on sedimentary environments.The Chengkou-Fangxian-Xiangfan Fracture controlled the position of the platform,slope and basin,as well as the silica supply for chert deposition in basin.Sea level fluctuations controlled types of sediments and sedimentary facies on the platform.In the study area,there are good reservoir rocks,including dolomites,grainstones,debris flow deposits,sandstones,and conglomerates;there are good source rocks,including black shales,dark micrites,and chert beds;and there are also good reservoir-source rock assemblages.The hydrocarbon potential of the study area is great. | YU KuanHong JIN ZhenKui SU Kui DONG XiaoDong ZHANG Wei DU HongYu CHEN Ying ZHANG WeiDan | 2013 | Science China Earth Sciences2013，56，6： | 9 |
| 6 | Creep properties and resistivity-ultrasonic-AE responses of cemented gangue backfill column under high-stress area显示文摘To investigate the creep and instability properties of a cemented gangue backfill column under a highstress area,the uniaxial compression creep tests were conducted by single-step and multi-step loading of prismatic samples made of cemented gangue backfill material(CGBM)under the high stressstrength ratio.The creep damage was monitored using an electrical resistivity device,ultrasonic testing device,and acoustic emission(AE)instrument.The results showed that the CGBM sample has a creep hardening property.The creep failure strength(CFS)is slightly larger than the uniaxial compressive strength(UCS),ranging in ratio from 108.9%to 116.5%.The instantaneous strain,creep strain,and creep rate increase with increasing stress-strength ratio in the single-step loading creep tests.The instantaneous strain and creep strain decrease first and then increase during the multi-step loading creep process.The axial creep strain of the CGBM column can be expressed by the viscoelastic-plastic creep model.Creep instability is caused by the accumulation of strain energy under multi-step loading and the continuous lateral expansion at the unconstrained middle position during the creep process.The creep stability of a CGBM column in a high-stress area can be monitored based on the variation of electrical resistivity,ultrasonic pulse velocity(UPV),and AE signals. | Hongyu Ran Yuxia Guo Guorui Feng Tingye Qi Xianjie Du | 2021 | International Journal of Mining Science and Technology2021，31，3： | 7 |
| 7 | Jixuecao(Herba Centellae Asiaticae) alleviates mesangial cell proliferation in IgA nephropathy by inducing mitofusin 2 expression显示文摘OBJECTIVE:To investigate the effect of mitofusin 2 (Mfn2) and its downstream signaling pathway on glomerular mesangial cells (GMCs) proliferation in IgA nephropathy (IgAN),as well as the mechanism of action of Jixuecao (Herba Centellae Asiaticae,HCA) in the treatment of IgAN.METHODS:Adenovirus-mediated Mfn2 gene transfection and Mfn2 expression were analyzed by real-time polymerase chain reaction (PCR) and Western blotting.IgA1 induced the proliferation of GMCs,which were then treated with HCA.Cell proliferation was detected with cell counting kit-8 (CCK-8),and Mfn2 expression was analyzed by real-time PCR and western blotting.An IgAN animal model was also established and treated with HCA.GMCs proliferation was detected by hematoxylin-eosin staining,mitochondrial structure was analyzed by electron microscopy,mitochondrial function was determined by the Clark oxygen electrode method,and the expression of Mfn2,Phospho-extracellular regulated protein kinases1/2 (P-ERK1/2),Cyclin-dependent kinase 2 (CDK2),Phospho-p27 (p-p27),and cyclin A was analyzed by Western blotting.RESULTS:In vitro,HCA inhibited GMCs in a concentration-dependent manner in association with the upregulation of Mfn2 expression.The overexpression of Mfn2 inhibited IgA1-induced GMCs proliferation and elevated the effect of HCA.In vivo,treatment with HCA could alleviate albuminuria and creatinine and GMCs proliferation.These effects were related to the upregulation of Mfn2,p-p27 and inhibition of p-ERK1/2,CDK2,and cyclinA.Mitochondrial swelling,vacuolar degeneration,and reduction of respiratory control rate were identified in IgAN,but HCA could improve the mitochondrial structure and function.CONCLUSION:HCA inhibited GMCs proliferation via the upregulation Mfn2 and the inhibition of Ras-Raf-ERK/MAPK.We revealed that changes of mitochondrial structure and function are associated with IgAN,but that HCA can improve these mitochondrial features. | Chen Hongyu Du Yuanyuan Li Yayu Zeng Jiali Miao Jianxia Jiang Xue | 2019 | Journal of Traditional Chinese Medicine2019，39，3： | 6 |
| 8 | Distinct beneficial effect of Sn on the corrosion resistance of Cr-Mo low alloy steel显示文摘In this work,the beneficial effect of Sn addition on the corrosion resistance mechanism of Cr-Mo low alloy steel was studied.Results demonstrated that Sn improves the corrosion resistance of the steel matrix mainly by influencing the microstructural transformation.Sn addition and the synergistic effect of Sn,Cr,and Mo promote the formation of α-FeOOH,SnO_(2),SnO,Cr(OH)_(3),and molybdates,lead to the improved protection and stability of the rust layer.This synergistic effect also endows the inner rust layer with cation selectivity,preventing the further penetration of Cl-and inhibiting the localized corrosion of steel. | Meihui Sun Xiaojia Yang Cuiwei Du Zhiyong Liu Yong Li Yumin Wu Hongyu San Xiandong Su Xiaogang Li | 2021 | Journal of Materials Science & Technology2021，，22： | 6 |
| 9 | Integrated genomic analysis identifies deregulated JAK/STAT-MYC-biosynthesis axis in aggressive NK-cell leukemia显示文摘好攻击的 NK 房间白血病(ANKL ) 是在从亚洲的人之中是更流行的 NK 房间瘤的一种稀罕形式并且中央并且南美洲。病人们通常在天以内死到月,甚至在收到迅速的治疗学的管理以后。这里,我们由集成整个染色体执行了 ANKL 的第一全面研究, transcriptome 并且定序指向,象功能的试金一样的 cytokine 数组。在 JAK-STAT 小径的变化在 48% 被识别(14/29 ) ANKL 病人,当细胞外的 STAT3 激发器 IL10 被 56 褶层的一般水准提高时(P < 0.0001 ) 在检查的所有病人的血浆。另外的经常变异的基因包括的 TP53 (34%) , TET2 (28%) , CREBBP (21%) 和 MLL2 (21%) 。耐心的 NK 白血病房间在多重新陈代谢的小径显示出 STAT3 phosphorylation, MYC 表示和 transcriptional 活动的突出的激活。机能上地, STAT3 激活和 MYC 表示为 ANKL 房间的增长和幸存是批评的。发信号的 STAT 调整了发信号的 MYC 抄写节目,和两 STAT, MYC 抄写被要求维持核苷酸合成和 glycolysis 的激活。一起, JAK-STAT 小径在 ANKL 为 genomic 改变和 IL10 刺激代表一个主要目标。这最新发现的 JAK/STAT-MYC-biosynthesis 轴可以在对待白血病的这种子类型为新奇治疗学的策略的发展提供机会。 | Liang Huang Dan Liu Na Wang Shaoping Ling Yuting Tang Jun Wu Lingtong Hao Hui Luo Xuelian Hu Lingshuang Sheng Lijun Zhu Di Wang Yi Luo Zhen Shang Min Xiao Xia Mao Kuangguo Zhou Lihua Cao Lili Dong Xinchang Zheng Pinpin Sui Jianlin He Shanlan Mo Jin Yan Qilin Ao Lugui Qiu Hongsheng Zhou Qifa Liu Hongyu Zhang Jianyong Li Jie Jin Li Fu Weili Zhao Jieping Chen Xin Du Guoliang Qing Hudan Liu Xin Liu Gang Huang Ding Ma Jianfeng Zhou Qian-fei Wang | 2018 | Cell Research2018，28，2： | 5 |
| 10 | Hexagonal boron nitride nanosheet for effective ambient N2 fixation to NH3显示文摘Industrial production of NH3 from N2 and H2 significantly relies on Haber-Bosch process,which suffers from high energy consume and CO2 emission.As a sustainable and environmentally-benign alternative process,electrochemical artificial N2 fixation at ambient conditions,however,is highly required efficient electrocatalysts.In this study,we demonstrate that hexagonal boron nitride nanosheet (h-BNNS) is able to electrochemically catalyze N2 to NH3.In acidic solution,h-BNNS catalyst attains a high NH3 formation rate of 22.4 μg·h-1·mg-1cat.and a high Faradic efficiency of 4.7% at-0.75 V vs.reversible hydrogen electrode,with excellent stability and durability.Density functional theory calculations reveal that unsaturated boron at the edge site can activate inert N2 molecule and significantly reduce the energy barrier for NH3 fonmation. | Ya Zhang Huitong Du Yongjun Ma Lei Ji Haoran Guo Ziqi Tian Hongyu Chen Hong Huang Guanwei Cui Abdullah M. Asiri Fengli Qu Liang Chen Xuping Sun | 2019 | Nano Research2019，12，4： | 5 |
| 11 | Simultaneous formation of trimetallic Pt-Ni-Cu excavated rhombic dodecahedrons with enhanced catalytic performance for the methanol oxidation reaction显示文摘有挖掘结构的 Multimetallic 基于磅的合金由于他们的组合、词法的 tunability,高特定的表面区域,和出色的电镀物品催化的活动吸引了大兴趣。此处,我们报导 trimetallic Pt-Ni-Cu 的第一灵巧的一个壶合成高度与接近 100% 的收益挖掘了菱形的十二面体(ERD ) 。更重要地,这些高度一致的 nanocrystals 有三在尺寸上的可存取的挖掘表面,在丰富的走的原子被观察的地方。得益于高度挖掘的菱形的十二面体组织,电子并且在 trimetallic 合金以内的 synergistic 效果,和丰富的走的原子,同样准备的 trimetallic Pt-Ni-Cu ERD 与商业 Pt/C 和二金属的 Pt-Cu ERD 和 Pt-Ni-Cu 稳固的菱形的十二面体相比为甲醇的电镀物品氧化展出提高的电镀物品催化的表演稳固的菱形的十二面体( SRD )。 | Min Tang Shuiping Luo Kai Wang Hongyu Du Rinrada Sriphathoorat Peikang Shen | 2018 | Nano Research2018，11，9： | 3 |
| 12 | New opportunities and challenges of natural products research:When target identification meets single-cell multiomics显示文摘Natural products, and especially the active ingredients found in traditional Chinese medicine(TCM), have a thousand-year-long history of clinical use and a strong theoretical basis in TCM. As such,traditional remedies provide shortcuts for the development of original new drugs in China, and increasing numbers of natural products are showing great therapeutic potential in various diseases. This paper reviews the molecular mechanisms of action of natural products from different sources used in the treatment of inflammatory diseases and cancer, introduces the methods and newly emerging technologies used to identify and validate the targets of natural active ingredients, enumerates the expansive list of TCM used to treat inflammatory diseases and cancer, and summarizes the patterns of action of emerging technologies such as single-cell multiomics, network pharmacology, and artificial intelligence in the pharmacological studies of natural products to provide insights for the development of innovative natural product-based drugs. Our hope is that we can make use of advances in target identification and singlecell multiomics to obtain a deeper understanding of actions of mechanisms of natural products that will allow innovation and revitalization of TCM and its swift industrialization and internationalization. | Yuyu Zhu Zijun Ouyang Haojie Du Meijing Wang Jiaojiao Wang Haiyan Sun Lingdong Kong Qiang Xu Hongyue Ma Yang Sun | 2022 | Acta Pharmaceutica Sinica B2022，12，11： | 3 |
| 13 | Electric field controlled superlubricity of fullerene-based host–guest assembly显示文摘Controlling friction by the electric field is a promising way to improve the tribological performance of a variety of movable mechanical systems.In this work,the assembly structure and microscale superlubricity of a host–guest assembly are effectively controlled by the electric field.With the help of the scanning tunneling microscopy(STM)technique,the host–guest assembly structures constructed by the co-assembly of fullerene derivative(Fluorene-C60)with macrocycles(4B2A and 3B2A)are explicitly characterized.Combined with density functional theory(DFT),the distinct different assembly behaviors of fullerene derivatives are revealed at different probe biases,which is attributed to the molecular polarity of the fullerene derivative.Through the control on the adsorption behavior,the friction coefficient of host–guest assembly is demonstrated to be controllable in the electric field by using atomic force microscopy(AFM).At positive probe bias,the friction coefficient of the host–guest assembly is significantly reduced and achieves superlubricity(μmin=0.0049).The efforts not only help us gain insight into the host–guest assembly mechanism controlled by the electric field,but also promote the further application of fullerene in micro-electro-mechanical systems(MEMS). | Shanchao Tan Hongyu Shi Xin Du Kunpeng Wang Haijun Xu Junhua Wan Ke Deng Qingdao Zeng Yuhong Liu | 2023 | Nano Research2023，16，1： | 1 |
| 14 | Modified function projective synchronization of chaotic system显示文摘 | Du Hongyue Qingshuang Zeng Changhong Wang | 2009 | Chaos Solitons and Fractals2009，42，04： | 1 |
| 15 | Clinical observation of serum IL- 18 ,IL- 10 andSlL-2R levels in patients with chronic hepati- tis C pre and post antiviral treatment 显示文摘 | JIA Hongyu DU Jie ZHU Sihe | 2003 | Chinese Medical Jouonal2003，116，4： | 1 |
| 16 | A new method for improving the inductively coupled data transmission rate of mooring buoy based on carrier signal frequency selection显示文摘In the inductively coupled data transmission system of the mooring buoy, the carrier signal frequency of the transmission channel is limited due to the inherent characteristics of the system, resulting in limited channel bandwidth. The limited channel bandwidth limits the increase in inductively coupled data transmission rate.In order to improve the inductively coupled data transmission rate of mooring buoy as much as possible without damaging the data transmission performance, a new method was proposed in this paper. The method is proposed to improve the data transmission rate by selecting the appropriate carrier signal frequencies based on the principle of maximizing the amplitude value of amplitude-frequency characteristic curve of the system. Research has been done according to this method as follows. Firstly, according to the inductively coupled transmission mooring buoy structure, the inductively coupled data transmission circuit model was established. The binary frequency shift keying(2FSK) digital signal modulation mode was selected. Through theoretical analysis, the relation between the carrier signal frequency and the data transmission performance, the relation between the carrier signal frequency and the 2FSK signal bandwidth were obtained. Secondly, the performance and the bandwidth of the signal transmission were studied for the inherent characteristics of the actual inductively coupled data transmission system. The amplitude-frequency characteristic of the system was analyzed by experiments. By selecting the appropriate carrier signal frequency parameters, an excellent data transmission performance was guaranteed and a large 2FSK signal bandwidth was obtained. Finally, an inductively coupled data transmission rate optimization experiment and a bit error rate analysis experiment were designed and carried out. The results show that the high-speed and reliable data transmission of the system was realized and the rate can reach 100 kbps. | Rong Du Xingfei Li Shaobo Yang Hongyu Li | 2020 | Nanotechnology and Precision Engineering2020，3，2： | 1 |
| 17 | Function projective synchronization in complex dynamical networks with time delay via hybrid feedback control显示文摘 | Du Hongyue Shi Peng Lu Ning | 2013 | Nonlinear Analysis:Real World Applications2013，14，2： | 1 |
| 18 | Function projective synchronization in complex dynamical networks with time delay via hybrid feedback control显示文摘 | Du Hongyue Shi Peng Lu Ning | 2013 | Nonlinear Analysis:Real World Applications2013，14，2： | 1 |
| 19 | Enhanced removal of soluble Cr (VI) by using zero-valent iron composite supported by surfactant-modified zeolites 显示文摘 | Dang Hongyu Zhang Yongxiang Peiwen Du | 2017 | Water Science and Technology2017，70，8： | 1 |
| 20 | Phthalimide and Naphthalimide end-Capped Diketopyrrolopyrrole for Organic Photovoltaic Applications显示文摘二个小分子作为终端作为中央强壮的领受人单位和 phthalimide/naphthalimide 与一个 DPP 核心说出 PI-DPP 和 NI-DPP 弱领受人被设计并且综合。热行为,光、电气化学的性质,以及这二材料的光电的表演上的终端 phthalimide/naphthalimide 单位的效果系统地被学习。周期的 voltammetry 表明两个分子的最低没有住的分子的 orbitals (LUMO )(^-3.6 eV ) 对普通电子施主(P3HT ) 和领受人(PCBM ) 中间。当与 PCBM 相配时,当与 P3HT 相配时,在在 DPP 和 PCBM 之间,以及在 P3HT 和 DPP 之间的足够的驱动力应该为激子分离被创造的地方,这显示 PI-DPP 和 NI-DPP 可以特别地用作电子施主,并且作为电子领受人。用作电子施主材料, PI-DPP 和 NI-DPP 设备由分别地与 PCBM 相配展出了 0.90% 和 0.76% 的低力量变换效率(PCE ) 。并且 NI-DPP 的潜力的初步的评估作为施主材料,和 P3HT 用 P3HT 作为电子领受人材料被执行: NI-DPP 设备显示出0.6%的 PCE ,与开的电路电压( V 0.7 V 的 OC ),短路电流密度( J 1.91 mAcm -2,和45%的一个fill 因素( FF )的 SC )。 | Ming Chen Chenchen Du Xiaolei Ren Maoheng Yi Jinduo Yi Chufeng Chen Feng Liu Minjie Li Changqi Ma Hongyu Wang | 2017 | Chinese Journal of Chemistry2017，35，9： | 1 |
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