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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Study of new catalysts based on vanadium oxide supported on mesoporous silica for the partial oxidation of methane to formaldehyde:Catalytic properties and reaction mechanism显示文摘 | NGUYEN L D LORIDANT S LAUNAY H PIGAMO A DUBOIS J L MILLET J M | | 0，，01： | 1 |
| 3 | From Rumors to Facts, and Facts to Rumors: The Role of Certainty Decay in Consumer Communications 显示文摘 | Dubois D Derek D R Zakary L T | 2011 | Journal of Marketing Research2011，48，6： | 1 |
| 4 | Mo2V-Te- (Nb)-O mixed metal oxides prepared by hydrothermal synthesis for catalytic selective oxidations of propane and propene to acrylic acid 显示文摘 | VITRY D MORIKAWA Y DUBOIS J L | 2003 | Applied Catalysis2003，251，2： | 1 |
| 5 | Two cytosolic glutamine synthetase isoforms of maize are specifically involved in the control of grain production 显示文摘 | Martin A Lee J Kichey T Gerentes D Zivy M Tatout C Dubois F Balliau T Valot B Davanture M Laforgue T T Quillere I Coque M Gallais A Moro M B G Bethencourt L Habash D Z Lea P J Charcosset A Perez P Murigneux A Sakakibara H Edwards K J Hirel B | 2006 | The Plant Cell2006，18，11： | 1 |
| 6 | Armored RNA technology for production ofribonuclease-resistant viral RNA controls andstandards显示文摘 | Pasloske B L Walkerpeach C R Obermoeller R D Winkler M DuBois D B | 1998 | J Clin Microbiol1998，36，12： | 1 |
| 7 | Developments in breeding for horizontal and vertical fungus resistance in roses 显示文摘 | de Vries D P Dubois L A M | 2001 | Acta Horticulturae2001，552，： | 1 |
| 8 | Ribonuclease-resistant RNA controls(Armored RNA)for reverse transcription-PCR,branched DNA,and genotyping assays for hepatitis C virus显示文摘 | WalkerPeach C R Winkler M DuBois D B Pasloske B L | 1999 | Clin Chem1999，45，12： | 1 |
| 9 | Genetic variation of rose cultivars for direct shoot organogenesis显示文摘 | DUBOIS L A M de VRIES D P KOOT A | 1997 | Acta Horticulturae1997，447，： | 1 |
| 10 | Screening of Aqueous Amine-Based Solvents for Postcombustion CO2 Capture by Chemical Absorption 显示文摘 | Dubois L Thomas D | 2012 | Chemical Engineering & Technology2012，35，3： | 1 |
| 11 | TG1050,an immunotherapeutic to treat chronic hepatitis B,induces robust T cells and exerts an antiviral effect in HBVpersistent mice显示文摘 | Martin P Dubois C Jacquier E Dion S ManciniBourgine M Godon O Kratzer R Lelu-Santolaria K Evlachev A Meritet J F Schlesinger Y Villeval D Strub J M Van Dorsselaer A Marchand J B Geist M Brandely R Findeli A Boukhebza H Menguy T Silvestre N Michel M L InchauspéG | 2015 | Gut2015，64，12： | 1 |
| 12 | The direct regeneration of adventitious bud on leaf explants of glass house-grown cut rose cuhivars 显示文摘 | Dubois L A M de Vries D P | 1995 | Acta Horticulturae1995，424，： | 1 |
| 13 | Peer victimization and rejection: Investigation of an integrative model effects on emotional, behavioral, and academic adjustment in early adolescence显示文摘 | LOPEZ C DUBOIS D L | 2005 | Journal of Clinical Child and Adolescent Psychology2005，34，1： | 1 |
| 14 | Genetic variation of rosecuhivars for direct shoot organogenesis 显示文摘 | Dubois L A M de Vries D P Koot A | 1997 | Acta Horticulturae1997，447，： | 1 |
| 15 | Influence of the compaction process on the air void homogeneity of as- phalt mixtures samples 显示文摘 | Dubois V Roche C D L Burban O | 2010 | Construction and Build- ing Materials2010，24，6： | 1 |
| 16 | Free radical branching of polylactide by reactive extrusion 显示文摘 | Carlson D Dubois P Nie L | 1998 | Polymer Engineering b- Science1998，38，2： | 1 |
| 17 | Frontiers,opportunities,and challenges in biochemical and chemical catalysis of CO2fixation显示文摘 | Appel A M Bercaw J E Bocarsly A B Dobbek H DuBois D L Dupuis M Ferry J G Fujita E Hille R Kenis P J A Kerfeld C A Morris R H Peden C H F Portis A R Ragsdale S W Rauchfuss T B Reek J N H Seefeldt L C Thauer R K Waldrop G L | 2013 | Chemical Reviews2013，113，8： | 1 |
| 18 | Aneurysmal bone cysts:percutaneous embolization with an alcoholic solution:series of 18 cases显示文摘 | Herbreteau D Dubois J | 1998 | Radiology1998，208，： | 1 |
| 19 | Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock 显示文摘 | Sakr Y L Dubois M J De Backer D | 2004 | Crit Care Med2004，32，9： | 1 |
| 20 | Conversion of methanol to olefins over cobalt-, manganese- and nickel-incorporated SAPO-34 molecular sieves 显示文摘 | DUBOIS D R OBRZUT D L LIU J | 2003 | Fuel Process Technology2003，83，： | 1 |
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