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| 1 | An integrated approach for increasing breeding efficiency in apple and peach in Europe显示文摘Despite the availability of whole genome sequences of apple and peach,there has been a considerable gap between genomics and breeding.To bridge the gap,the European Union funded the FruitBreedomics project(March 2011 to August 2015)involving 28 research institutes and private companies.Three complementary approaches were pursued:(i)tool and software development,(ii)deciphering genetic control of main horticultural traits taking into account allelic diversity and(iii)developing plant materials,tools and methodologies for breeders.Decisive breakthroughs were made including the making available of ready-to-go DNA diagnostic tests for Marker Assisted Breeding,development of new,dense SNP arrays in apple and peach,new phenotypic methods for some complex traits,software for gene/QTL discovery on breeding germplasm via Pedigree Based Analysis(PBA).This resulted in the discovery of highly predictive molecular markers for traits of horticultural interest via PBA and via Genome Wide Association Studies(GWAS)on several European genebank collections.FruitBreedomics also developed pre-breeding plant materials in which multiple sources of resistance were pyramided and software that can support breeders in their selection activities.Through FruitBreedomics,significant progresses were made in the field of apple and peach breeding,genetics,genomics and bioinformatics of which advantage will be made by breeders,germplasm curators and scientists.A major part of the data collected during the project has been stored in the FruitBreedomics database and has been made available to the public.This review covers the scientific discoveries made in this major endeavour,and perspective in the apple and peach breeding and genomics in Europe and beyond. | Francois Laurens Maria JoséAranzana Pere Arus Daniele Bassi Marco Bink Joan Bonany Andrea Caprera Luca Corelli-Grappadelli Evelyne Costes Charles-Eric Durel Jehan-Baptiste Mauroux Hélène Muranty Nelson Nazzicari Thierry Pascal Andrea Patocchi Andreas Peil Bénédicte Quilot-Turion Laura Rossini Alessandra Stella Michela Troggio Riccardo Velasco Eric van de Weg | 2018 | Horticulture Research2018，5，1： | 10 |
| 2 | Laparoscopic Colectomy for Cancer Is Not Inferior to Open Surgery Based on 5-Year Data From the COST Study Group Trial显示文摘 | James Fleshman Daniel J. Sargent Erin Green Mehran Anvari Steven J. Stryker Robert W. Beart Michael Hellinger Richard Flanagan Walter Peters Heidi Nelson | 2007 | Annals of Surgery2007，，4： | 7 |
| 3 | Processing techniques of selected oilseed by-products of potential use in animal feed: Effects on proximate nutrient composition, amino acid profile and antinutrients显示文摘The effects of processing by autoclaving(AC), soaking(SK), short-term fermentation(S-TF, 4 d) and longterm fermentation(L-TF, 14 d) on the nutritional composition, amino acid profile and some antinutrients were determined for cottonseed meal(CSM), groundnut meal(GNM) and groundnut husk(GH) in this study. After processing, crude protein content improved by 11% after L-TF, and crude lipid content 25%after SK for CSM; crude protein content improved by 27% after S-TF and L-TF, and crude lipid content 13%after SK for GNM. Soaking and fermentation were shown to significantly increase essential amino acid contents by 44%(SK, methionine) in CSM and 46% in GNM(L-TF, histidine). Phosphorus content was reduced by 59% in CSM and 57% in GNM by L-TF. All processing techniques, with the exception of AC,reduced phytic acid and gossypol contents in CSM and GNM. It was concluded that SK and fermentation were simple, cost-effective, and efficient ways to improve the nutritional value of the selected oilseed byproducts. | Collins P.Duodu Daniel Adjei-Boateng Regina E.Edziyie Nelson W.Agbo Godfred Owusu-Boateng Bodil K.Larsen Peter V.Skov | 2018 | Animal Nutrition2018，，4： | 7 |
| 4 | Global epidemiology of hepatitis B and hepatitis C in people who inject drugs: results of systematic reviews显示文摘 | Paul K Nelson Bradley M Mathers Benjamin Cowie Holly Hagan Don Des Jarlais Danielle Horyniak Louisa Degenhardt | 2011 | The Lancet . 2011 (9791)2011，，： | 2 |
| 5 | Acute Radiation Injury: Contingency Planning for Triage, Supportive Care, and Transplantation显示文摘 | Daniel Weisdorf Nelson Chao Jamie K. Waselenko Nicholas Dainiak James O. Armitage Ian McNiece Dennis Confer | 2006 | Biology of Blood and Marrow Transplantation2006，，6： | 2 |
| 6 | 试验室研究一种新型透水性混凝土路面砖的块型设计过程显示文摘本文介绍一种专门为城市透水性路面而设计的混凝土路面砖的块型。Cantabria大学与当地一家生产企业合作,并得到地方政府的支持,其目的是在西班牙北部应用透水型路面砖作为城市可持续性排水系统。在提出多个不同外形和尺寸的块型设计方案后,根据路面开孔率、砖连锁咬合接触面和美学角度,先从理论上进行初步对比,选择一种块型——有四种不同形状的透水槽沟;然后在Cantabia大学公路试验室里进行测试,检测不同形状的开孔对路面透水性能的影响。共进行两组测试,第一组假设路面开孔存在不同堵塞状况和坡度,以确定最佳的开孔形状;第二组用选定的混凝土路面砖,分析透水性路面的水径流。根据初步试验结果,生产企业订制模型、生产了第一批新型混凝土路面砖,并已着手推向市场。新型透水性混凝土路面砖的设计研究过程经历了无数次成功和失败,本文仅为丰富技术探讨内容,无意使其成为技术导则。 | Daniel Castro J.R.Bayon Jorge Rodriguez Nelson Gonzalez-Angullo 陈义荣(译) 杜建东(校) 刘黎(校) | 2008 | 建筑砌块与砌块建筑2008，，4： | 2 |
| 7 | Conditional Heteroskedasticity in Asset Returns: A New Approach显示文摘 | Nelson Daniel B | 1991 | Econometrica1991，，59： | 1 |
| 8 | Impression Cytology显示文摘 | J. Daniel Nelson | 1988 | Cornea1988，，1： | 1 |
| 9 | Conditional heteroskedasticity in asset returns: A new approach显示文摘 | Nelson Daniel B | 1991 | Econometrica1991，59，： | 1 |
| 10 | Understanding the cost of establishing marine protected areas显示文摘 | Ashley McCrea-Strub Dirk Zeller Ussif Rashid Sumaila Jay Nelson Andrew Balmford Daniel Pauly | 2010 | Marine Policy2010，，1： | 1 |
| 11 | Compressed sensing for resolution enhancement of hyperpolarized 13 C flyback 3D-MRSI显示文摘 | Simon Hu Michael Lustig Albert P. Chen Jason Crane Adam Kerr Douglas A.C. Kelley Ralph Hurd John Kurhanewicz Sarah J. Nelson John M. Pauly Daniel B. Vigneron | 2008 | Journal of Magnetic Resonance2008，，2： | 1 |
| 12 | Incidence and risk factors for agranulocytosis in Latin American countries—the Latin Study显示文摘 | Nelson Hamerschlak Eliane Maluf Alexandre Biasi Cavalcanti álvaro Avezum Júnior José Eluf-Neto Roberto Passeto Falc?o Irene Gyongyvér Heidemarie Lorand-Metze Daniel Goldenberg Cézar Leite Santana Daniela de Oliveira Werneck Rodrigues Leny Nascimento da Mo | 2008 | European Journal of Clinical Pharmacology2008，，9： | 1 |
| 13 | I-dentification of a broadly active phage lyric enzyme with lethal activity against antibiotic-resistance Entercococcus faecalis and Enterococcus faecium显示文摘 | PAULINE YOONG RAYMOND SCHUCH DANIEL NELSON | 2004 | J Bacteriol2004，，： | 1 |
| 14 | Conditional Heteroskedasticity in Asset Returns: A New Approach 显示文摘 | Nelson Daniel B | 1991 | Econometrica1991，59，2： | 1 |
| 15 | The Si cycle in the Pacific sector of the Southern Ocean: seasonal diatom production in the surface layer and export to the deep sea显示文摘 | Daniel E Sigmon David M Nelson Mark A Brzezinski | 2002 | Deep-Sea Research Part II2002，，9： | 1 |
| 16 | A comparison of laparoscopieally assisted and open colectomy for colon eancer显示文摘 | Heidi Nelson Daniel J Sam Wieand | 2004 | N Engl Meal2004，350，： | 1 |
| 17 | Conditional heteroskedasticity in asset returns:A new approach显示文摘 | Nelson Daniel B | 1990 | Econometrica1990，59，： | 1 |
| 18 | Challenges and Recommendations for Early Identification of Metastatic Disease in Prostate Cancer显示文摘 | E. David Crawford Nelson N. Stone Evan Y. Yu Phillip J. Koo Stephen J. Freedland Susan F. Slovin Leonard G. Gomella E. Roy Berger Thomas E. Keane Paul Sieber Neal D. Shore Daniel P. Petrylak | 2013 | Urology2013，，： | 1 |
| 19 | Endolysins as Antimicrobials显示文摘 | Daniel C. Nelson Mathias Schmelcher Lorena Rodriguez-Rubio Jochen Klumpp David G. Pritchard Shengli Dong David M. Donovan | 2012 | Advances in Virus Research2012，，： | 1 |
| 20 | Scheduling with multiple performance measure:the one-machine case显示文摘 | NELSON R T SARIN R K DANIELS R L | 1986 | Management Science1986，32，4： | 1 |
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