|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Prospective validation of the Barcelona Clinic Liver Cancer staging system显示文摘 | Umberto Cillo Alessandro Vitale Francesco Grigoletto Fabio Farinati Alberto Brolese Giacomo Zanus Daniele Neri Patrizia Boccagni Nela Srsen Francesco D’Amico Francesco Antonio Ciarleglio Alessio Bridda Davide Francesco D’Amico | 2006 | Journal of Hepatology2006，，4： | 2 |
| 3 | Response to Therapy as a Criterion for Awarding Priority to Patients With Hepatocellular Carcinoma Awaiting Liver Transplantation显示文摘 | Alessandro Vitale Francesco D’Amico Anna Chiara Frigo Francesco Grigoletto Alberto Brolese Giacomo Zanus Daniele Neri Amedeo Carraro Francesco Enrico D’Amico Patrizia Burra Francesco Russo Paolo Angeli Umberto Cillo | 2010 | Annals of Surgical Oncology2010，，9： | 1 |
| 4 | Role of epigenetics in human aging and longevity: genome-wide DNA methylation profile in centenarians and centenarians’ offspring显示文摘 | Davide Gentilini Daniela Mari Davide Castaldi Daniel Remondini Giulia Ogliari Rita Ostan Laura Bucci Silvia M. Sirchia Silvia Tabano Francesco Cavagnini Daniela Monti Claudio Franceschi Anna Maria Blasio Giovanni Vitale | 2013 | AGE2013，，5： | 1 |
| 5 | Long Term Follow-up and Outcome of Liver Transplantation for Alcoholic Liver Disease: A Single Center Case-control Study显示文摘 | Maurizio Biselli Annagiulia Gramenzi Massimo Del Gaudio Matteo Ravaioli Giovanni Vitale Stefano Gitto Gian Luca Grazi Antonio Daniele Pinna Pietro Andreone Mauro Bernardi | 2010 | Journal of Clinical Gastroenterology2010，，1： | 1 |
| 6 | Default-mode network connectivity in cognitively unimpaired patients with Parkinson disease显示文摘 | Alessandro Tessitore Fabrizio Esposito Carmine Vitale Gabriella Santangelo Marianna Amboni Antonio Russo Daniele Corbo Giovanni Cirillo Paolo Barone Gioacchino Tedeschi | 2012 | Neurology2012，，23： | 1 |
| 7 | Response to Therapy as a Criterion for Awarding Priority to Patients With Hepatocellular Carcinoma Awaiting Liver Transplantation显示文摘 | Alessandro Vitale Francesco D’Amico Anna Chiara Frigo Francesco Grigoletto Alberto Brolese Giacomo Zanus Daniele Neri Amedeo Carraro Francesco Enrico D’Amico Patrizia Burra Francesco Russo Paolo Angeli Umberto Cillo | 2010 | Annals of Surgical Oncology2010，，9： | 1 |
| 8 | Microfabricated intracortical extracellular matrix-microelectrodes for improving neural interfaces显示文摘Intracortical neural microelectrodes,which can directly interface with local neural microcircuits with high spatial and temporal resolution,are critical for neuroscience research,emerging clinical applications,and brain computer interfaces(BCI).However,clinical applications of these devices remain limited mostly by their inability to mitigate inflammatory reactions and support dense neuronal survival at their interfaces.Herein we report the development of microelectrodes primarily composed of extracellular matrix(ECM)proteins,which act as a bio-compatible and an electrochemical interface between the microelectrodes and physiological solution.These ECM-microelectrodes are batch fabricated using a novel combination of micro-transfer-molding and excimer laser micromachining to exhibit final dimensions comparable to those of commercial silicon-based microelectrodes.These are further integrated with a removable insertion stent which aids in intracortical implantation.Results from electrochemical models and in vivo recordings from the rat’s cortex indicate that ECM encapsulations have no significant effect on the electrochemical impedance characteristics of ECM-microelectrodes at neurologically relevant frequencies.ECM-microelectrodes are found to support a dense layer of neuronal somata and neurites on the electrode surface with high neuronal viability and exhibited markedly diminished neuroinflammation and glial scarring in early chronic experiments in rats. | Wen Shen Suradip Das Flavia Vitale Andrew Richardson Akshay Ananthakrishnan Laura A.Struzyna Daniel P.Brown Naixin Song Murari Ramkumar Timothy Lucas DKacy Cullen Brian Litt Mark G.Allen | 2018 | Microsystems & Nanoengineering2018，4，1： | 1 |
| 9 | A disabling cervical compressive myelopathy with normal JOA score显示文摘 | Daniel Laguerre Thomas Wavasseur Jean-Marc Vital Jean-Rodolphe Vignes | 2013 | Clinical Neurology and Neurosurgery2013，，7： | 1 |
| 10 | When to perform hepatic resection for intermediate‐stage hepatocellular carcinoma显示文摘 | Alessandro Cucchetti Benjamin Djulbegovic Athanasios Tsalatsanis Alessandro Vitale Iztok Hozo Fabio Piscaglia Matteo Cescon Giorgio Ercolani Francesco Tuci Umberto Cillo Antonio Daniele Pinna | 2015 | Hepatology2015，，3： | 1 |
| 11 | Large periampullary villous tumor of the duodenum显示文摘 | Marco Cavallini Daniele Cavaniglia Francesco Felicioni Valeria Vitale Emanuela Pilozzi Vincenzo Ziparo | 2007 | Journal of Hepato - Biliary - Pancreatic Surgery2007，，5： | 1 |
| 12 | Biliopancreatic diversion for obesity at eighteen years显示文摘 | Nicola Scopinaro Ezio Gianetta Gian Franco Adami Daniele Friedman Enrico Traverso Giuseppe M. Marinari Sonia Cuneo Bruno Vitale Fabrizio Ballari Maurizio Colombini Giorgio Baschieri Virgilio Bachi | 1996 | Surgery1996，，3： | 1 |
| 13 | Phylogeographic insights of the lowland species Cheirolophus sempervirens in the southwestern Iberian Peninsula显示文摘西南的伊比利亚人半岛是一个重要 biogeographic 区域,显示出高生物多样性层次并且招待为欧洲植物群的几通常认为的冰川的 refugia。这里,我们学习地中海的基因差异和结构,越过它在 SW 伊伯利亚半岛的整个分发范围的 thermophilous 植物 Cheirolophus sempervirens (Asteraceae ) ,解开一些塑造这个南部的 refugia 热点的一般 biogeographic 模式的一个工具。空基因差异在定序屏蔽的 cpDNA 被观察。尽管如此, AFLP 数据揭示了在人口之中的高水平基因区别相关到他们的地理地点。我们的结果在更温暖的阶段由于殖民向北在冰川的时期和随后的创始人效果期间在南部的伊比利亚人 refugia 建议更长的种类坚持(即,南部的丰富到北纯净模式) 。另外,我们的 phylogeographic 分析在 Ch 以内显示二个分开的基因系的存在。sempervirens,在 refugia 以内与 refugia 一致为 SW 伊伯利亚半岛支持多重次要的 refugia 的假设模型。 | Daniel Vitales Alfredo Garcia-Fernandez Teresa Garnatje Jaume Pellicer Joan Valles | 2016 | Journal of Systematics and Evolution2016，54，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员