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| 1 | Double-shell structure of Al_3(Zr,Sc) precipitate induced by thermomechanical treatment of Al-Zr-Sc alloy cable显示文摘A spheroidal Al_3(Zr,Sc) precipitate with a double-shell structure, comprising a Sc-enriched core enveloped by a Zr-enriched inner shell and a Sc-enriched outer shell(~9 nm in thickness), appears in an Al-0.2 Zr-0.1 Sc alloy cable after thermomechanical treatment. The average diameter of the spheroidal Al_3(Zr,Sc) precipitate is approximately 80 nm. The double-shelled Al_3(Zr,Sc) precipitate presents three different interfaces and is semi-coherent with the Al matrix. Atom probe tomography(APT) analyses further show that the outer shell of Al_3(Zr,Sc) precipitate is Sc element enrichment. The electrical conductivity of Al-0.2 Zr-0.1 Sc alloy cable increases by 6.5 MS/m within the aging time from 0.2 to 100 h at 350 ℃, with double-shelled Al_3(Zr,Sc)precipitate. | Jiayi Zhang Tao Hu Danqing Yi Hongxuan Wang Bin Wang | 2019 | Journal of Rare Earths2019，37，6： | 8 |
| 2 | A new strategy to iteratively update scalable universal quantitative models for the testing of azithromycin by near infrared spectroscopy显示文摘The training set of a universal near infrared (NIR) model for quantitative analysis of a drug should cover as many samples of this drug in the market as possible. Inevitably the model may fail for new products that have different excipients and production processes. In such circumstances the model should be updated. We here propose a new strategy to iteratively update a universal NIR quantitative model for azithromycin. We prove that universal quantitative models generated from this new strategy are comparably effective for azithromycin injection powders and azithromycin tablets, compared to the strategy using hierarchical clustering method which we reported previously. Furthermore, we establish the correlation coefficient r between a new sample and the training set samples can be used to decide whether or not the model should be updated. | ZOU WenBo FENG YanChun DONG JiXiong SONG DanQing HU ChangQin | 2013 | Science China Chemistry2013，56，4： | 5 |
| 3 | Metallic vanadium trioxide intercalated with phase transformation for advanced aqueous zinc-ion batteries显示文摘Aqueous zinc-ion batteries have broad application prospects due to the eco-friendliness,cost-economy and high safety.However,the scarcity of high-performance cathodes with outstanding rate capability and long lifespan has affected their development.Herein,we report a metallic vanadium trioxide material intercalated with phase transformation as cathode applied in aqueous zinc-ion batteries.It offers satisfactory electrochemical performances with a high specific capacity(435 mAh g^(-1) at 0.5 A g^(-1)),decent power density(5.23 kW kg^(-1))and desired energy density(331 Wh kg^(-1)),as well as good cyclability.The superior performance originates from the stable structure and fast Zn^(2+)diffusion,enabled by the pre-intercalation of Zn^(2+)and water molecules. | Kang Hu Danqing Jin Yao Zhang Longwei Ke Huan Shang Yan Yan Huijuan Lin Kun Rui Jixin Zhu | 2021 | Journal of Energy Chemistry2021，30，10： | 1 |
| 4 | Disruption of E-Cadherin by Matrix Metalloproteinase Directly Mediates Epithelial-Mesenchymal Transition Downstream of Transforming Growth Factor-β1 in Renal Tubular Epithelial Cells显示文摘 | Guoping Zheng James Guy Lyons Thian Kui Tan Yiping Wang Tzu-Ting Hsu Danqing Min Lena Succar Gopala K. Rangan Min Hu Beric R. Henderson Stephen I. Alexander David C.H. Harris | 2009 | The American Journal of Pathology2009，，2： | 1 |
| 5 | Preparation of nickel-coated titanium carbide particulates and their use in the production of reinforced iron matrix composites显示文摘 | Danqing Yi Pengchao Yu Bin Hu Huiqun Liu Bin Wang Yong Jiang | 2013 | Materials and Design2013，，： | 1 |
| 6 | Effects of pH, Fe, and Cd on the uptake of Fe 2+ and Cd 2+ by rice显示文摘 | Danqing Liu Chunhua Zhang Xue Chen Yazhou Yang Shu Wang Yujiao Li Hao Hu Ying Ge Wangda Cheng | 2013 | Environmental Science and Pollution Research2013，，12： | 1 |
| 7 | Practice of reperfusion in patients with ST-segment elevation myocardial infarction in China:findings from the Improving Care for Cardiovascular Disease in China–Acute Coronary Syndrome project显示文摘Background:Reperfusion therapy is fundamental for ST-segment elevation myocardial infarction(STEMI).However,the details of contemporary practice and factors associated with reperfusion therapy in China are largely unknown.Therefore,this study aimed to explore reperfusion practice and its associated factors among hospitalized patients with STEMI in China.Methods:Patients with STEMI who were admitted to 159 tertiary hospitals from 30 provinces in China were included in the Improving Care for Cardiovascular Disease in China–Acute Coronary Syndrome project from November 2014 to December 2019.The associations of the characteristics of patients and hospitals with reperfusion were examined using hierarchical logistic regression.The associations between therapies and in-hospital major adverse cardiovascular events were examined with a mixed effects Cox regression model.Results:Among the 59,447 patients,37,485(63.1%)underwent reperfusion,including 4556(7.7%)receiving fibrinolysis and 32,929(55.4%)receiving primary percutaneous coronary intervention(PCI).The reperfusion rate varied across geographical regions(48.0%–73.5%).The overall rate increased from 60.0%to 69.7%from 2014 to 2019,mainly due to an increase in primary PCI within 12 h of symptom onset.Timely PCI,but not fibrinolysis alone,was associated with a decreased risk of inhospital major adverse cardiovascular events compared with no reperfusion,with an adjusted hazard ratio(95%confidence interval)of 0.64(0.54,0.76)for primary PCI at<12 h,0.53(0.37,0.74)for primary PCI at 12 to 24 h,0.46(0.25,0.82)for the pharmaco-invasive strategy,and 0.79(0.54,1.15)for fibrinolysis alone.Conclusions:Nationwide quality improvement initiatives should be strengthened to increase the reperfusion rate and reduce inequality in China.Trial registration:www.ClinicalTrials.gov,NCT02306616。 | Yiqian Yang Yongchen Hao Jun Liu Na Yang Danqing Hu Zhaoqing Sun Dong Zhao Jing Liu on behalf of the Improving Care for Cardiovascular Disease in China-Acute Coronary Syndrome(CCC-ACS)Investigators | 2022 | Chinese Medical Journal2022，135，23： | 0 |
| 8 | Evolution and development of potent monobactam sulfonate candidate IMBZ18g as a dual inhibitor against MDR Gram-negative bacteria producing ESBLs显示文摘A series of new monobactam sulfonates is continuously synthesized and evaluated for their antimicrobial efficacies against Gram-negative bacteria.Compound 33a(IMBZ18G)is highly effective in vitro and in vivo against clinically intractable multi-drug-resistant(MDR)Gram-negative strains,with a highly druglike nature.The checkerboard assay reveals its significant synergistic effect withβ-lactamase inhibitor avibactam,and the MIC values against MDR enterobacteria were reduced up to 4—512folds.X-ray co-crystal and chemoproteomic assays indicate that the anti-MDR bacteria effect of 33a results from the dual inhibition of the common PBP3 and some class A and Cβ-lactamases.Accordingly,preclinical studies of 33a alone and 33a-avibactam combination as potential innovative candidates are actively going on,in the treatment ofβ-lactamase-producing MDR Gram-negative bacterial infections. | Zhiwen Li Zhihao Guo Xi Lu Xican Ma Xiukun Wang Rui Zhang Xinxin Hu Yanxiang Wang Jing Pang Tianyun Fan Yonghua Liu Sheng Tang Haigen Fu Jingpu Zhang Yinghong Li Xuefu You Danqing Song | 2023 | Acta Pharmaceutica Sinica B2023，13，7： | 0 |
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