| 1 | Experimental study on flow heterogeneity of shale bedding fractures based on full-diameter cores显示文摘A self-designed full-diameter core experimental facility was used to evaluate the flow heterogeneity of bedding fractures at four radial directions under different closure pressures and injection rates,using full-diameter cores retaining original natural bedding fractures.The distribution morphology of bedding surface affects the conductivity of bedding fractures,and the flow capacity of bedding fractures in four radial directions varies greatly with the closure pressure and injection rate.The rougher the fracture surface,the greater the flow capacity varies with the closure pressure.For unsupported bedding fractures,the mean percentage error(MPE)of the conductivity in four radial directions increase gradually with the increase of the closure pressure.This phenomenon is especially prominent in deep rock samples.It is indicated that the flow heterogeneity of bedding fractures tends to increase with the closure pressure.When proppant is placed in the fracture,at a low closure pressure,due to the combined effects of self-support of rough fracture surface,proppant instability and uneven proppant placement,the flow heterogeneity is greater than that when proppant is not placed at the same closure pressure;however,with the increase of the closure pressure,the proppant becomes compact and stable,and the flow heterogeneity is mitigated gradually. | ZHU Juhui ZENG Jing GENG Zhoumei LI Yongming WANG Tengfei LI Deqi PAN Yong WANG Juan | 2023 | Petroleum Exploration and Development2023，50，5： | 0 |
| 2 | Genomic landscape of mitochondrial DNA insertions in 23 bat genomes:characteristics,loci,phylogeny,and polymorphism显示文摘The transfer of mitochondrial DNA to the nuclear genome gives rise to the nuclear DNA sequences of mitochon-drial origin(NUMTs),considered as a driving force in genome evolution.In this study,NUMTs in 23 bat genomes were investigated and compared systematically.The results showed that NUMTs existed in 22 genomes except for Noctilio leporinus,suggesting that mitochondrial fragment insertion in the nuclear genome was a common event in bat genomes.However,remarkable variations in NUMTs number,cumulative length,and proportion in the nu-clear genome were discovered across bat species.Further orthologous NUMT loci analysis of the Phyllostomidae family indicated that the NUMTs insertion events in bat genomes were homoplasy-free.The NUMTs were mainly inserted into the intergenic regions,particularly,co-localized with repetitive sequences(especially transposable el-ements).However,several NUMTs were inserted into genes,some of which were in the exon region of functional genes.One NUMT in the genome of Pteropus alecto surprisingly matched with cDNA of ATP8B3 that provided evidence of NUMTs with coding function.Phylogenic analysis on NUMTs originating from COXI and COXII loci highlighted 2 clusters of Yinpterochiroptera and Yangochiroptera for Chiroptera.Seven NUMTs from Rhinolophus ferrumequinum were amplified,and the sequencing results confirmed the reliability of the NUMT analysis.One of them was polymorphic for the presence or absence of the NUMT insertion,and each genotype of NUMT loci showed a distinct regional distribution pattern.The information obtained in this study provides novel insights into the NUMT organization and features in bat genomes and establishes a basis for further studying of the evolution of bat species. | Guojun ZHANG Deqi GENG Qiulin GUO Wei LIU Shufen LI Wujun GAO Yongfei WANG Min ZHANG Yilin WANG Yanzhen BU Hongxing NIU | 2022 | Integrative Zoology2022，17，5： | 0 |
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