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| 1 | Wheat genomic study for genetic improvement of traits in China显示文摘Bread wheat(Triticum aestivum L.)is a major crop that feeds 40%of the world’s population.Over the past several decades,advances in genomics have led to tremendous achievements in understanding the origin and domestication of wheat,and the genetic basis of agronomically important traits,which promote the breeding of elite varieties.In this review,we focus on progress that has been made in genomic research and genetic improvement of traits such as grain yield,end-use traits,flowering regulation,nutrient use efficiency,and biotic and abiotic stress responses,and various breeding strategies that contributed mainly by Chinese scientists.Functional genomic research in wheat is entering a new era with the availability of multiple reference wheat genome assemblies and the development of cutting-edge technologies such as precise genome editing tools,highthroughput phenotyping platforms,sequencing-based cloning strategies,high-efficiency genetic transformation systems,and speed-breeding facilities.These insights will further extend our understanding of the molecular mechanisms and regulatory networks underlying agronomic traits and facilitate the breeding process,ultimately contributing to more sustainable agriculture in China and throughout the world. | Jun Xiao Bao Liu Yingyin Yao Zifeng Guo Haiyan Jia Lingrang Kong Aimin Zhang Wujun Ma Zhongfu Ni Shengbao Xu Fei Lu Yuannian Jiao Wuyun Yang Xuelei Lin Silong Sun Zefu Lu Lifeng Gao Guangyao Zhao Shuanghe Cao Qian Chen Kunpu Zhang Mengcheng Wang Meng Wang Zhaorong Hu Weilong Guo Guoqiang Li Xin Ma Junming Li Fangpu Han Xiangdong Fu Zhengqiang Ma Daowen Wang Xueyong Zhang Hong-Qing Ling Guangmin Xia Yiping Tong Zhiyong Liu Zhonghu He Jizeng Jia Kang Chong | 2022 | Science China(Life Sciences)2022，65，9： | 9 |
| 2 | microRNA-29b is a novel mediator of Sox2 function in the regulation of somatic cell reprogramming显示文摘成纤维细胞能由 Yamanaka 因素(OSKM ) 的申请是进导致的 pluripotent 干细胞(iPSCs ) 的 reprogrammed,但是位于这 reprogramming 下面的机制仍然保持糟糕理解。这里,我们报导 Sox2 直接调整内长的 microRNA-29b (miR-29b ) 表示为调停 OSKM 、调停 OSK 的 reprogramming 在 iPSC 产生和那 miR-29b 表情期间被要求。Dnmt3a 和 Dnmt3b 在 miR-29b 和那 Dnmt3a 和 Dnmt3b 表示的 vivo 目标的机械学的研究表演相反地在 reprogramming 期间与 miR-29b 表示被相关。而且, reprogramming 上的 miR-29b 的效果能被 Dnmt3a 或 Dnmt3b overexpression 堵住。进一步的实验显示发信号的 miR-29b-DNMT 显著地涉及 DNA methylation 相关的 reprogramming 事件的规定,例如 mesenchymal-to-epithelial 转变(相遇) 并且 Dlk1-Dio3 区域抄写。因此,我们的研究不仅表明 miR-29b 是 reprogramming 因素 Sox2 的一个新奇调停人而且为 Sox2 在驾驶表明调整 DNA 的轴的 miR-29b-DNMT 的 multistep 机制提供证据 methylation 相关的事件在 reprogramming 期间。 | Xudong Guo Qidong Liu Guiying Wang Songcheng Zhu Longfei Gao Wujun Hong Yafang Chen Minjuan Wu Houqi Liu Cizhong Jiang Jiuhong Kang | 2013 | Cell Research2013，23，1： | 9 |
| 3 | Controllable release of ibuprofen from size-adjustable and surface hydrophobic mesoporous silica spheres显示文摘 | Wujun Xu Qiang Gao Yao Xu Dong Wu Yuhan Sun Wanling Shen Feng Deng | 2008 | Powder Technology2008，，1： | 1 |
| 4 | Amino acid adsorptionon mesoporous materials: influence of types of amino acids, modification of mesoporous materials, and solution conditions 显示文摘 | Quang Gao Wujun Xu Yao Xu | 2008 | J PhysChem B2008，112，7： | 1 |
| 5 | A Novel Chimeric Low-Molecular-Weight Glutenin Subunit Gene From the Wild Relatives of Wheat Aegilops kotschyi and Ae. juvenalis: Evolution at the Glu-3 Loci显示文摘 | Li Xiaohui Ma Wujun Gao Liyan Zhang Yanzhen Wang Aili Ji Kangmin Wang Ke Appels Rudi Yan Yueming | 2008 | Genetics2008，，1： | 1 |
| 6 | Novel x-Type High-Molecular-Weight Glutenin Genes From Aegilops tauschii and Their Implications on the Wheat Origin and Evolution Mechanism of Glu-D1-1 Proteins显示文摘 | Zhang Yanzhen Li Xiaohui Wang Aili An Xueli Zhang Qian Pei Yuhe Gao Liyan Ma Wujun Appels Rudi Yan Yueming | 2008 | Genetics2008，，1： | 1 |
| 7 | Genomic landscape of mitochondrial DNA insertions in 23 bat genomes:characteristics,loci,phylogeny,and polymorphism显示文摘The transfer of mitochondrial DNA to the nuclear genome gives rise to the nuclear DNA sequences of mitochon-drial origin(NUMTs),considered as a driving force in genome evolution.In this study,NUMTs in 23 bat genomes were investigated and compared systematically.The results showed that NUMTs existed in 22 genomes except for Noctilio leporinus,suggesting that mitochondrial fragment insertion in the nuclear genome was a common event in bat genomes.However,remarkable variations in NUMTs number,cumulative length,and proportion in the nu-clear genome were discovered across bat species.Further orthologous NUMT loci analysis of the Phyllostomidae family indicated that the NUMTs insertion events in bat genomes were homoplasy-free.The NUMTs were mainly inserted into the intergenic regions,particularly,co-localized with repetitive sequences(especially transposable el-ements).However,several NUMTs were inserted into genes,some of which were in the exon region of functional genes.One NUMT in the genome of Pteropus alecto surprisingly matched with cDNA of ATP8B3 that provided evidence of NUMTs with coding function.Phylogenic analysis on NUMTs originating from COXI and COXII loci highlighted 2 clusters of Yinpterochiroptera and Yangochiroptera for Chiroptera.Seven NUMTs from Rhinolophus ferrumequinum were amplified,and the sequencing results confirmed the reliability of the NUMT analysis.One of them was polymorphic for the presence or absence of the NUMT insertion,and each genotype of NUMT loci showed a distinct regional distribution pattern.The information obtained in this study provides novel insights into the NUMT organization and features in bat genomes and establishes a basis for further studying of the evolution of bat species. | Guojun ZHANG Deqi GENG Qiulin GUO Wei LIU Shufen LI Wujun GAO Yongfei WANG Min ZHANG Yilin WANG Yanzhen BU Hongxing NIU | 2022 | Integrative Zoology2022，17，5： | 0 |
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