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| 1 | Plant Prime Editors Enable Precise Gene Editing in Rice Cells显示文摘Genome editing is revolutionizing plant research and crop breeding.Sequence-specific nucleases(SSNs)such as zinc finger nuclease(ZFN)and TAL effector nuclease(TALEN)have been used to create site-specific DNA double-strand breaks and to achieve precise DNA modifications by promoting homology-directed repair(HDR)(Steinert et al.,2016;Voytas,2013).Later,RNA-guided SSNs such as CRISPR-Cas9,Cas12a,Cas12b,and their variants were applied for genome editing in plants(Li et al.,2013;Nekrasov et alM 2013;Tang et al.,2017;Zhong et al.,2019;Ming et al.,2020;Tang et al.,2019).However,HDR relies on simultaneous delivery of SSNs and DNA donors,which has been challenging in plants(Steinert et al.,2016;Zhang et aL,2019).Another challenge for realizing efficient HDR in plants is that DNA repair favors nonhomologous end joining(NHEJ)pathways over HDR in most cell types(Puchta,2005;Qi et al.,2013). | Xu Tang Simon Sretenovic Qiurong Ren Xinyu Jia Mengke Li Tingting Fan Desuo Yin Shuyue Xiang Yachong Guo Li Liu Xuelian Zheng Yiping Qi Yong Zhang | 2020 | Molecular Plant2020,13,5: | 20 |
| 2 | Ecologically-friendly operation scheme for the Jinping cascaded reservoirs in the Yalongjiang River, China显示文摘在河里保存关键生态系统性质的 Ecologically 友好的水库操作过程目的,当最小化社会经济的兴趣的牺牲时。集中于 Jinping 的这研究作为案例研究串联了水库。一个优化模型被开发在除去的自然隧道节,和年度力量生产探索在目标鱼种(Schizothorax chongi ) 的生态的流动要求(EFR ) 之间的平衡。为隧道的 EFR 被 Tennant 方法和一个鱼产地模型分别地决定。优化模型被使用一个适应真实代码的基因算法解决。相应于生态的流动系列的几种操作情形用优化模型被评估。通过比较,一个最佳的运作的计划,在除去的隧道把相对低的力量生产损失与比较喜欢的生态的流动政体相结合,为串联水库被建议。在推荐计划下面,进在旱季的 Dahewan 河活动范围的分泌物从 36 ~ 50 m ^啜 3 ^/s。这将在要保存的隧道启用至少 50% 目标鱼产地,以 2.5% 仅仅年度力量生产损失的成本。学习证明 EFR 的使用是以一个生态地友好的方法的水库操作的优化的一条有效途径。,为另外的重要的鱼种类和生态系统类似的建模工作,由结果的领域确认补充了,被需要以便固定影响的河生态系统的长期的保存[出版摘要] | Duan CHEN Qiuwen CHEN Ruonan LI Koen BLANCKAERT Desuo CAI | 2014 | Frontiers of Earth Science2014,8,2: | 2 |
| 3 | Performance of Cotton Fabric Treated with an Amino-terminated Hyperbranched Pol- ymer 显示文摘 | Feng Zhang Desuo Zhang Yuyue Chert | 2008 | Fibers and Polymers2008,9,5: | 1 |
| 4 | In situ synthesis of silver nanoparticles on silk fabric with PNPi'or an- tibacterial finishing显示文摘 | Desuo Zhang Guoyang William Toh Hong Lin | 2012 | J Mater Sci2012,47,: | 1 |
| 5 | In sitn generation and deposition of nano-ZnO on cotton fabric by hypcrbranched polymer for its functional fini- shing 显示文摘 | ZHANG Desuo CHEN Ling FANG Di | 2013 | Textile Research Journal2013,83,15: | 1 |
| 6 | The comparative study on the ecological sensitivity analysis in Huixian karst wetland, China显示文摘 | Zhang Mingwu Jin Haijiang Cai Desuo | 2010 | Procedia Environmen- tal Sciences2010,2,: | 1 |
| 7 | Antibacterial cotton fabric grafted with silver nanoparticles and its excellent- laundering durability显示文摘 | Desuo Zhang Ling Chen ChuanfengZang | 2013 | CarbohydrPolym2013,,92: | 1 |
| 8 | In situ synthesis of silver nanoparticles on silk fabric with PNP for antibacterial finishing 显示文摘 | ZHANG Desuo TOH Guoyang William LIN Hong | 2012 | Journal of Materials Science2012,47,15: | 1 |
| 9 | The antimicrobial activity of the cotton fabric grafted with an amino-terminated hyperbranched polymer 显示文摘 | ZHANG Feng ZHANG Desuo CHEN Yuyue | 2009 | Cellulose2009,16,: | 1 |
| 10 | Expanding plant genome-editing scope by an engineered iSpyMacCas9 system that targets A-rich PAM sequences显示文摘The most popular CRISPR-SpCas9 systemrecognizes canonical NGG protospacer adjacent motifs(PAMs).Previously engineered SpCas9 variants,such as Cas9-NG,favor G-rich PAMs in genome editing.In this manuscript,we describe a new plant genome-editing system based on a hybrid iSpyMacCas9 platform that allows for targeted mutagenesis,C to T base editing,and A to G base editing at A-rich PAMs.This study fills amajor technology gap in the CRISPR-Cas9 system for editing NAAR PAMs in plants,which greatly expands the targeting scope of CRISPR-Cas9.Finally,our vector systems are fully compatible with Gateway cloning and will work with all existing single-guide RNA expression systems,facilitating easy adoption of the systems by others.We anticipate that more tools,such as prime editing,homology-directed repair,CRISPR interference,and CRISPR activation,will be further developed based on our promising iSpyMac-Cas9 platform. | Simon Sretenovic Desuo Yin Adam Levav Jeremy D.Selengut Stephen M.Mount Yiping Qi | 2021 | Plant Communications2021,2,2: | 1 |
| 11 | In situ synthesis of silver nanoparticles on silk fabric with PNP for antibacterial finishing显示文摘 | Desuo Zhang Guoyang William Toh Hong Lin Yuyue Chen | 2012 | Journal of Materials Science2012,,: | 1 |
| 12 | Morphology con trol of silver nano-crystals through a polyol synthesis显示文摘 | Luo Xiaolin Chen Yashao Yang Desuo | 2011 | Solid State Sci2011,,13: | 1 |
| 13 | The comparative study on the ecological sensitivity analysis in Huixian karst wetland, China显示文摘 | ZHANG Mingwu JIN Haijiang CAI Desuo | 2010 | Procedia Environmental Sciences2010,2,: | 1 |
| 14 | The antimicrobial activity of the cotton fabric grafted with anamino-terminated hyperbranched polymer显示文摘 | ZHANG Feng ZHANG Desuo CHEN Yuyue | 2009 | Cellulose2009,16,: | 1 |
| 15 | In situ synthesis of silver nanoparticles on silk fabric with PNP for antibacterial finishing 显示文摘 | ZHANG Desuo TOH Guoyang William LIN Hong | 2012 | Journal of Materials Science2012,47,15: | 1 |
| 16 | An Analysis on the Heat Resistance of Rice Germplasm Resources during Flowering Period显示文摘56 Chinese rice core germplasm resources,18 foreign rice germplasm resources and 6 restorer lines are subjected to high temperature stress during flowering period. Based on relative spikelet fertility rate,rice heat resistance is evaluated. The results show that different resistance to high temperature exists in different varieties,and 6 new rice varieties present high heat resistance. | Zhongping ZHA Desuo YIN Bingliang WAN Chunhai JIAO | 2016 | Asian Agricultural Research2016,8,6: | 0 |
| 17 | In-situ sugar-templated porous elastomer sensor with high sensitivity for wearables显示文摘Fabrication of elastic pressure sensors with low cost,high sensitivity,and mechanical durability is important for wearables,electronic skins and soft robotics.Here,we develop high-sensitivity porous elastomeric sensors for piezoresistive and capacitive pressure detection.Specifically,a porous polydimethylsiloxane(PDMS)sponge embedded with conductive fillers of carbon nanotubes(CNTs)or reduced graphene oxide(rGO)was fabricated by an in-situ sugar template strategy.The sensor demonstrates sensitive deformation to applied pressure,exhibiting large and fast response in resistance or capacitance for detection of a wide range of pressure(0‒5 kPa).PDMS,as a high-elasticity framework,enables creation of sensors with high sensitivity,excellent stability,and durability for long-term usage.The highest sensitivities of 22.1 and 68.3 kPa−1 can be attained by devices with 5%CNTs and 4%rGO,respectively.The geometrics of the sponge sensor is tailorable using tableting technology for different applications.The sensors demonstrate finger motion detection and heart-rate monitoring in real-time,as well as a capacitive sensor array for identification of pressure and shape of placed objects,exhibiting good potential for wearables and human-machine interactions. | Meng REN Ying FANG Yufan ZHANG Heli DENG Desuo ZHANG Hong LIN Yuyue CHEN Jiaqing XIONG | 2022 | Frontiers of Materials Science2022,16,2: | 0 |