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| 1 | Viral effector protein manipulates host hormone signaling to attract insect vectors显示文摘 | Dewei Wu Tiancong Qi Wan-Xiang Li Haixia Tian Hua Gao Jiaojiao Wang Jin Ge Ruifeng Yao Chunmei Ren Xian-Bing Wang Yule Liu Le Kang Shou-Wei Ding Daoxin Xie | 2017 | Cell Research2017，27，3： | 20 |
| 2 | Enhancement Expression of bFGF in Chinese Patients with Moyamoya Disease显示文摘Objective To detect the content of the basic fibroblast growth factor in blood samples of patients with Moyamoya disease, and investigate the relationship between Moyamoya disease and the basic fibroblast growth factor. Methods This tissue microarray study included 24 cases of superficial temporal artery samples, 15 cases of Moyamoya disease, and 9 cases of normal arteries as control, and bFGF immunofluorescence assay was applied to test the samples. The number of positive cells and total cells of the muscular layer and the endothelium layer were counted separately in every picture, the positive rates were calculated, and the experimental data were analyzed statistically. Results The bFGF immunofluorescence staining of smooth muscular layer cells, intima cells and endothelial cells from the moyamoya disease group were obviously stronger than that from the control group (P<0.01). Conclusion The enhancement expression of bFGF in the Moyamaya disease group implicates that bFGF plays an important part in the pathogenesis of Moyamoya disease. | ZOU DeWei ZHAO JiZong ZHANG Dong WANG Shuo WANG KeDa ZHANG Yan | 2011 | Biomedical and Environmental Sciences2011，24，1： | 12 |
| 3 | Biodegradation of aniline by Candida tropicalis AN1 isolated from aerobic granular sludge显示文摘Aniline-degrading microbes were cultivated and acclimated with the initial activated sludge collected from a chemical wastewater treatment plant. During the acclimation processes, aerobic granular sludge being able to effectively degrade aniline was successfully formed, from which a preponderant bacterial strain was isolated and named as AN1. Effects of factors including pH, temperature, and second carbon/nitrogen source on the biodegradation of aniline were investigated. Results showed that the optimal conditions for the biodegradation of aniline by the strain AN1 were at pH 7.0 and 28-35°C. At the optimal pH and temperature, the biodegradation rate of aniline could reach as high as 17.8 mg/(L·hr) when the initial aniline concentration was 400 mg/L. Further studies revealed that the addition of 1 g/L glucose or ammonium chloride as a second carbon or nitrogen source could slightly enhance the biodegradation efficiency from 93.0% to 95.1%-98.5%. However, even more addition of glucose or ammonium could not further enhance the biodegradation process but delayed the biodegradation of aniline by the strain AN1. Based on morphological and physiological characteristics as well as the phylogenetic analysis of 26S rDNA sequences, the strain AN1 was identified as Candida tropicalis. | Dianzhan Wang Guanyu Zheng Shimei Wang Dewei Zhang Lixiang Zhou | 2011 | Journal of Environmental Sciences2011，23，12： | 10 |
| 4 | 3D C_f/SiBCN composites prepared by an improved polymer infiltration and pyrolysis显示文摘Using liquid poly(methylvinyl)borosilazanes(PMVBSZ)as precursor,carbon fiber reinforced SiBCN matrix composites(C_f/SiBCN)were fabricated by a modified polymer infiltration and pyrolysis(PIP)process.With dicumyl peroxide added as cross-linking agent,the PMVBSZ could be solidified at a low temperature of 120℃,leading to a high ceramic yield of~70%.The cross-linking mechanism and ceramization processes of the precursor were investigated in detail.Moreover,a modified infiltration technology was developed,which improved the efficiency and protected the precursor against moist air during PIP.Consequently,the obtained C_f/SiBCN composites had an oxygen content of around 1.22 wt%.Benefiting from the high ceramic yield and high efficiency of the modified PIP,C_f/SiBCN composites with an open porosity of~10%and uniform microstructure were obtained after only 7 cycles of PIP.The flexural strength and fracture toughness of the derived C_f/SiBCN composites were 371 MPa and 12.9 MPa·m^(1/2),respectively.This work provides a potential route for the fabrication of high performance C_f/SiBCN composites. | Qi DING Dewei NI Zhen WANG Hao ZHONG Hongda WANG Haijun ZHOU Yanmei KAN Shaoming DONG | 2018 | Journal of Advanced Ceramics2018，7，3： | 9 |
| 5 | CuTiNiZrV Amorphous Alloy Foils for Vacuum Brazing of TiAl Alloy to 40Cr Steel显示文摘Vacuum brazing of TiAl alloy to 40Cr steel sheets was conducted with newly developed CuTiNiZrV amorphous foils. It was found that a diffusion layer,filler metal and reaction layer existed in the brazed seam. The diffusion layer in the joint brazed with Cu43.75Ti37.5Ni6.25Zr6.25V6.25(at.%) foil was flat and thin,containing Ti19Al6 and Ti2Cu intermetallic compounds; however,the diffusion layer brazed with Cu37.5Ti25Ni12.5Zr12.5V12.5 foil was uneven with bulges,consisting of essentially Ti-based solute solution. The foil with 12.5 at.% V showed inferior spreadability compared to that with 6.25 at.% V at brazing temperature. However,fracture happened along the diffusion layer with 6.25 at.% V foil due to the formation of brittle intermetallic phases,but the joints brazed with 12.5 at.% V foil failed through the TiAl substrate. These results show that designing amorphous alloy with less Ti and more V for brazing TiAl alloy to steel is appropriate. | Honggang Dong Zhonglin Yang Zengrui Wang Dewei Deng Chuang Dong | 2015 | Journal of Materials Science & Technology2015，31，2： | 7 |
| 6 | Dynamic route guidance algorithm based onartificial immune system显示文摘To improve the performance of the K-shortest paths search in intelligent traffic guidance systems,this paper proposes an optimal search algorithm based on the intelligent optimization search theory and the metaphor mechanism of vertebrate immune systems.This algorithm,applied to the urban traffic network model established by the node-expanding method,can expediently realize K-shortest paths search in the urban traffic guidance systems.Because of the immune memory and global parallel search ability from artificial immune systems,K shortest paths can be found without any repeat,which indicates evidently the superiority of the algorithm to the conventional ones.Not only does it perform a better parallelism,the algorithm also prevents premature phenomenon that often occurs in genetic algorithms.Thus,it is especially suitable for real-time requirement of the traffic guidance system and other engineering optimal applications.A case study verifies the efficiency and the practicability of the algorithm aforementioned. | Licai YANG Jie LIN Dewei WANG Lei JIA | 2007 | 控制理论与应用(英文版)2007，5，4： | 7 |
| 7 | Materials evolution of bone plates for internal fixation of bone fractures:A review显示文摘Bone plates play a vital role in bone fracture healing by providing the necessary mechanical fixation for fracture fragments through modulating biomechanical microenvironment adjacent to the fracture site.Good treatment effect has been achieved for fixation of bone fracture with conventional bone plates,which are made of stainless steel or titanium alloy.However,several limitations still exist with traditional bone plates including loosening and stress shielding due to significant difference in modulus between metal material and bone tissue that impairs optimal fracture healing.Additionally,due to demographic changes and non-physiological loading,the population suffering from refractory fractures,such as osteoporosis fractures and comminuted fractures,is increasing,which imposes a big challenge to traditional bone plates developed for normal bone fracture repair.Therefore,optimal fracture treatment with adequate fixation implants in terms of materials and design relevant to special conditions is desirable.In this review,the complex physiological process of bone healing is introduced,followed by reviewing the development of implant design and biomaterials for bone plates.Finally,we discuss recent development of hybrid bone plates that contains bioactive elements or factors for fracture healing enhancement as a promising direction.This includes biodegradable Mg-based alloy used for designing bone screw-plates that has been proven to be beneficial for fracture healing,an innovative development that attracts more and more attention.This paper also indicates that the tantalum bone plates with porous structure are also emerging as a new fracture internal fixation implants.The reduction of the stress shielding is verified to be useful to accelerate bone fracture healing.Potential application of biodegradable metals may also avoid a second operation for implant removal.Further developments in biometals and their design for orthopedic bone plates are expected to improve the treatment of bone fracture,especially the refractory fractures. | Junlei Li Ling Qin Ke Yang Zhijie Ma Yongxuan Wang Liangliang Cheng Dewei Zhao | 2020 | Journal of Materials Science & Technology2020，36，1： | 5 |
| 8 | Reaction mechanism and microstructure development of ZrSi_(2) melt-infiltrated C_(f)/SiC-ZrC-ZrB_(2) composites:The influence of preform pore structures显示文摘Reactive melt infiltration(RMI)is an effective method for fabrication of highly dense carbon fiber reinforced ultra-high temperature ceramic matrix composites(Cf/UHTCs).In this work,C_(f)/SiC-ZrC-ZrB_(2)composites were fabricated by infiltrating ZrSi_(2)melt into porous C_(f)/B_(4)C-C preforms,where the physical and chemical reactions involved during the RMI process were identified and analyzed.Inhomogeneous infiltration between the inter-and intra-bundle pores was revealed,and was found to be strongly related to the pore structures of the C_(f)/B_(4)C-C preform.It is indicated that the inhomogeneous infiltration can be mitigated remarkably with increasing porosity and pore size of the preform.The effect of pore size on the RMI process was also investigated by a quantitative model,which agrees very well with the experiment results.It further indicates that the inhomogeneous infiltration can also be relieved at elevated RMI temperature.However,excessive infiltration at elevated temperature or more porous preform may cause serious erosion on interphase and fibers,leading to mechanical properties deterioration of the final composites. | Xiaowu Chen Dewei Ni Yanmei Kan Youlin Jiang Haijun Zhou Zhen Wang Shaoming Dong | 2018 | Journal of Materiomics2018，4，3： | 5 |
| 9 | Microstructure and mechanical properties of 3D Cf/SiBCN composites fabricated by polymer infiltration and pyrolysis显示文摘In this work,three-dimensional(3D)Cf/SiBCN composites were fabricated by polymer infiltration and pyrolysis(PIP)with poly(methylvinyl)borosilazane as SiBCN precursor.The 3D microstructure evolution process of the composites was investigated by an advanced X-ray computed tomography(XCT).The effect of dicumyl peroxide(DCP)initiator addition on the crosslinking process,microstructure evolution,and mechanical properties of the composites were uncovered.With the addition of a DCP initiator,the liquid precursor can cross-linking to solid-state at 120℃.Moreover,DCP addition decreases the release of small molecule gas during pyrolysis,leading to an improved ceramic yield 4.67 times higher than that without DCP addition.After 7 PIP cycles,density and open porosity of the final Cf/SiBCN composite with DCP addition are 1.73 g.cm^(-3)and〜10%,respectively,which are 143.0%higher and 30.3%lower compared with the composites without DCP addition.As a result,the flexural strength and elastic modulus of Cf/SiBCN composites with DCP addition(371 MPa and 31 GPa)are 1.74 and 1.60 times higher than that without DCP addition(213 MPa and 19.4 GPa),respectively. | Bowen CHEN Qi DING Dewei NI Hongda WANG Yusheng DING Xiangyu ZHANG Shaoming DONG | 2021 | Journal of Advanced Ceramics2021，10，1： | 4 |
| 10 | Oxide-based cathode materials for rechargeable zinc ion batteries:Progresses and challenges显示文摘With the increasing demands for electrical energy storage technologies,rechargeable zinc ion batteries(ZIBs)have been rapidly developed in recent years owing to their high safety,low cost and high energy storage capability.The cathode is an essential part of ZIBs,which hosts zinc ions and determines the capacity,rate and cycling performance of the battery.The mainstream cathodes for ZIBs are oxidebased materials with tunnel,layer or 3 D crystal structures.In this review,we mainly focus on the latest advanced oxide-based cathode materials in ZIBs,including manganese oxides,vanadium oxides,spinel compounds,and other metal oxide based cathodes.In addition,the mechanisms of zinc storage and recent development in cathode design have been discussed in detail.Finally,current challenges and perspectives for the future research directions of oxide-based cathodes in ZIBs are presented. | Yingze Zhou Fandi Chen Hamidreza Arandiyan Peiyuan Guan Yunjian Liu Yuan Wang Chuan Zhao Danyang Wang Dewei Chu | 2021 | Journal of Energy Chemistry2021，30，6： | 4 |
| 11 | Tectonic Landform of Quaternary Lakes and Its Implications for Deformation in the Northern Qinghai-Tibet Plateau显示文摘在北 Qinghai 西藏高原的 Hohxil 区域由众多的高原湖被占据,它长作为是构造产品被推断了。然而,到目前为止,小证据都没被发现支持这试验推理。在 Hohxil 区域的东方片断的 TM 卫星图象的地调查和 morphotectonic 分析表明库赛·莱克和耶卢苏·莱克是塑造 S 的拉开盆,它被左罢工滑倒主人差错 trending WNW-ESE 统治。二个湖的拉开距离被分析是 <15 20 km 和 15 km 分别地。基于指责的率的研究,拉开盆的开始年龄被建议是近似在早更新世。拉开盆 tectonics 进一步在北 Qinghai 西藏高原为广泛地分布式的大湖盆被认为是普通机制。盆和他们的实质的 intra 块滑动的这些拉开的地区性的分发建议那一左首砍应力,独立于著名罢工滑倒差错,被强加了在上越过北 Qinghai 西藏高原。因此, intra 块滑倒可以是在提供在印度和欧亚大陆之间的进行中的大陆大陆集中的高原外壳的材料的东方挤出的重要表情。在高原内地以内的拉开 tectonics 的展现由全球放系统(GPS ) 为最新建议的连续变丑提供领域证据和变丑的一种可能的式样越过北 Qinghai 西藏高原的测量。关于系统的构造地形开发,一个模型最后为拉开盆被建议。 | WANG An WANG Guocan LI Dewei XIE Defan LIU Demin | 2009 | Acta Geologica Sinica(English Edition)2009，83，1： | 3 |
| 12 | Digital AGC Based on Coherent Adjustment Cycle for DSSS Receiver显示文摘In order to meet the requirements for zero value stability of direct sequence spread spectrum(DSSS) signal processing in high dynamic scenario,digital automatic gain control(AGC) is employed to regulate power.However,conventional AGC causes degradation in the synchronization performance of DSSS receiver.Based on the theoretical analysis of the influence of digital AGC on DSSS signal synchronization,this paper proposes a new AGC algorithm,which is applicable to multi-channel digital DSSS signal receiver.By making power adjustment cycle and synchronization cycle coherent with each other adaptively,the influence of digital AGC on subsequent synchronization processing has been eliminated.Theoretical analysis,simulation results and experimental data verify the validity of the proposed algorithm.By virtue of the proposed algorithm,the influence of digital AGC on DSSS signal synchronization is eliminated.This algorithm applies to an aerospace engineering project successfully. | SHEN Yuyao WANG Yongqing SHENG Dewei WU Siliang | 2015 | China Communications2015，12，2： | 3 |
| 13 | Three-Dimensional Hierarchical Nanostructured Cu/Ni–Co Coating Electrode for Hydrogen Evolution Reaction in Alkaline Media显示文摘In this work,three-dimensional hierarchical nickel–cobalt alloy coating for hydrogen evolution cathode was fabricated by electrodeposition processes.The coatings’morphology evolves from sea cucumber-like nanostructure to caterpillar-like one with the increase of cobalt content.A large amount of nanometric‘‘steps,’’served as the active sites for hydrogen evolution reaction,were observed.According to Tafel polarization measurements,the exchange current density of the as-synthesized coating with hierarchical nanostructure was 21.9 times compared with that of flat nickel coating.In addition,the hierarchical coating also displayed good electrochemical stability from the galvanostatic test. | Ning Wang Tao Hang Dewei Chu Ming Li | 2015 | Nano-Micro Letters2015，7，4： | 2 |
| 14 | A Multicenter Application and Evaluation of the Oxford Classification of IgA Nephropathy in Adult Chinese Patients显示文摘 | Cai-Hong Zeng Weibo Le Zhaohui Ni Minfang Zhang Lining Miao Ping Luo Rong Wang Zhimei Lv Jianghua Chen Jiong Tian Nan Chen Xiaoxia Pan Ping Fu Zhangxue Hu Lining Wang Qiuling Fan Hongguang Zheng Dewei Zhang Yaping Wang Yanhong Huo Hongli Lin Shuni Chen Sh | 2012 | American Journal of Kidney Diseases2012，，5： | 2 |
| 15 | Cyst(e)ine in nutrition formulation promotes colon cancer growth and chemoresistance by activating mTORCl and scavenging ROS显示文摘Weight loss and cachexia are common problems in colorectal cancer patients;thus,parenteral and enteral nutrition support play important roles in cancer care.However,the impact of nonessential amino acid components of nutritional intake on cancer progression has not been fully studied.In this study,we discovered that gastrointestinal cancer patients who received cysteine as part of the parenteral nutrition had shorter overall survival(P<0.001)than those who did not.Cystine indeed robustly promotes colon cancer cell growth in vitro and in immunodeficient mice,predominately by inhibiting SESN2 transcription via the GCN2-ATF4 axis,resulting in mTORCl activation.mTORCl inhibitors Rapamycin and Everolimus block cystine-induced cancer cell proliferation.In addition,cystine confers resistance to oxaliplatin and irinotecan chemotherapy by quenching chemotherapy-induced reactive oxygen species via synthesizing glutathione.We demonstrated that dietary deprivation of cystine suppressed colon cancer xenograft growth without weight loss in mice and boosted the antitumor effect of oxaliplatin.These findings indicate that cyst(e)ine;as part of supplemental nutrition,plays an important role in colorectal cancer and manipulation of cyst(e)ine content in nutritional formulations may optimize colorectal cancer patient survival. | Jiao Wu Sai-Ching Jim Yeung Sicheng Liu Aiham Qdaisat Dewei Jiang Wenli Liu Zhuo Cheng Wenjing Liu Haixia Wang Lu Li Zhongmei Zhou Rong Liu Chuanyu Yang Ceshi Chen Runxiang Yang | 2021 | Signal Transduction and Targeted Therapy2021，6，6： | 2 |
| 16 | 胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。 | Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，9： | 2 |
| 17 | Porous tantalum-composited gelatin nanoparticles hydrogel integrated with mesenchymal stem cell-derived endothelial cells to construct vascularized tissue in vivo显示文摘The ideal scaffold material of angiogenesis should have mechanical strength and provide appropriate physiological microporous structures to mimic the extracellular matrix environment.In this study,we constructed an integrated three-dimensional scaffold material using porous tantalum(pTa),gelatin nanoparticles(GNPs)hydrogel,and seeded with bone marrow mesenchymal stem cells(BMSCs)-derived endothelial cells(ECs)for vascular tissue engineering.The characteristics and biocompatibility of pTa and GNPs hydrogel were evaluated by mechanical testing,scanning electron microscopy,cell counting kit,and live-cell assay.The BMSCs-derived ECs were identified by flow cytometry and angiogenesis assay.BMSCs-derived ECs were seeded on the pTa-GNPs hydrogel scaffold and implanted subcutaneously in nude mice.Four weeks after the operation,the scaffold material was evaluated by histomorphology.The superior biocompatible ability of pTa-GNPs hydrogel scaffold was observed.Our in vivo results suggested that 28 days after implantation,the formation of the stable capillary-like network in scaffold material could be promoted significantly.The novel,integrated pTa-GNPs hydrogel scaffold is biocompatible with the host,and exhibits biomechanical and angiogenic properties.Moreover,combined with BMSCs-derived ECs,it could construct vascular engineered tissue in vivo.This study may provide a basis for applying pTa in bone regeneration and autologous BMSCs in tissue-engineered vascular grafts. | Zhenhua Zhao Mang Wang Fei Shao Ge Liu Junlei Li Xiaowei Wei Xiuzhi Zhang Jiahui Yang Fang Cao Qiushi Wang Huanan Wang Dewei Zhao | 2021 | Regenerative Biomaterials2021，8，6： | 2 |
| 18 | Indirect space vector based modulation techniques for high-power multi- modular matrix converters显示文摘 | Wang Jiangcheng Wu Bin Xu Dewei | 2013 | Industrial Electronics Maga- zine IEEE2013，60，8： | 1 |
| 19 | Human tissue kallikrein induces hypotension in transgenic mice显示文摘 | Wang J Xiong W Yang Z Davis T Dewey MJ Chao J | 1994 | Hypertension1994，23，： | 1 |
| 20 | The mechanism of deep material transport and seismogenic environment of the Xiaojiang fault system revealed by 3-D magnetotelluric study显示文摘The Xiaojiang fault system(XJFS), located to the southeast of the Tibetan Plateau, has a complicated tectonic history and is an ideal location to study the Tibetan Plateau in terms of its deep material transport mechanism and the effects of past tectonic events. In this study, broadband and long-period magnetotelluric data were collected above this fault system and inverted to build a 3-D resistivity model of the lithosphere. As shown in the model, at upper-middle crustal depths, three high-resistivity anomalies separate the strike-slip faults located in the study area, which may be the remnants of the Emeishan large igneous province that was destroyed and modified by Cenozoic crustal activity. The lower crust is characterized by significant lowresistivity anomalies that extend downward to the upper mantle. The low-resistivity anomalies in the upper crust may be caused by brines or/and conductive minerals(e.g., graphite and sulfides), and the possible reason for the low-resistivity anomalies that were imaged in the lower crust and upper mantle may be the presence of hydrogen in nominally anhydrous minerals and partial melts. According to the seismic activity distribution and resistivity structure, we propose dividing the seismic activity of the study area into three categories: tectonic earthquakes, earthquakes with no active faults on the surface, and other scattered earthquakes with no general features. Seismic activities are controlled by tectonic activities, fluid transportation, and the adjustment of the Earth's stress field. It is believed that there is a mutually reinforcing relationship between seismic activity and deep fluids. Fluids could lower the frictional force in faults, promote movement, and thus induce earthquakes;on the other hand,seismic activities and the long-term strike-slip movements of faults could generate heat and increase the connectivity of fluids,which decreases the strength of the crust and facilitates the flow of fluids. Based on the resistivity model, it is demonstrated that the present tectonic activity in the XJFS is complicated and characterized by rigid block extrusion along strike-slip faults in the upper crust, ductile deformation with channel flow in the lower crust, and the upwelling of mantle materials. In combination with previous studies, our results indicate that the weak crustal materials from the Tibetan Plateau are blocked by(1) the lithosphere modified by the Emeishan plume and(2) the South China block when flowing through the Sichuan-Yunnan block. Therefore,these weak materials turn to the southwest direction along the XJFS, then pass through the Red River fault and enter the Indochina block. | Nian YU Xuben WANG Dewei LI Xin LI Enci WANG Wenxin KONG Tianyang LI | 2022 | Science China Earth Sciences2022，65，6： | 1 |
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