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| 1 | H5N1 influenza virus-specific miRNA-like small RNA increases cytokine production and mouse mortality via targeting poly(rC)-binding protein 2显示文摘H5N1 流行性感冒病毒的感染在所有流行性感冒病毒之中引起最高的死亡。位于如此的高病毒的致病力下面的机制不完全地被理解。这里,我们报导 H5N1 流行性感冒病毒编码象 microRNA 一样小 RNA, miR-HA-3p,它从茎被处理由 Argonaute 2 的包含环的病毒的 RNA 先锋,和戏在在 H5N1 感染期间提高 cytokine 生产的一个角色。miR-HA-3p poly 指向的机械学的学习表演(rC ) 有约束力的蛋白质 2 (PCBP2 ) 并且压制它的表达式。与 PCBP2 being 一致 RIG-I/MAVS-mediated 抗病毒的天生的免疫的一个重要否定管理者,由 miR-HA-3p 的 PCBP2 表示的抑制在感染 H5N1 的人的巨噬细胞和老鼠支持 cytokine 生产病毒。我们断定 miR-HA-3p 是首先识别的流行性感冒编码病毒的象 microRNA 一样功能的 RNA 碎片和贡献导致 H5N1 的 cytokine 暴风雨和死亡的一个新奇毒力因素。 | Xihan Li Zheng Fu Hongwei Liang Yanbo Wang Xian Qi Meng Ding Xinlei Sun Zhen Zhou Ying Huang Hongwei Gu Limin Li Xi Chen Donghai Li Quan Zhao Fenyong Li Hua Wang Jin Wang Ke Zen Chen-Yu Zhang | 2018 | Cell Research2018，28，2： | 12 |
| 2 | “Three essential elements”of the primary health care system:A comparison between California in the US and Guangdong in China显示文摘The primary health care system(PHCS)is the portal and basis for the national health delivery system.There are a number of elements which comprise the PHCS,but the system cannot be established and developed without the support of“three essential elements,”including general practitioners(GPs),health insurance,and government health investment.Through comparative analysis of the“three essential elements”of the PHCS between California in the US and Guangdong in China,this article indicates that there are three important aspects in developing a PHCS in China,as follows:training qualified GPs;establishing a diversified health insurance system to strengthen the policy connections between health insurance and the PHCS thereby increasing government health investment;and broadening health financing channels. | Minfang Huang Donghai Wei Louis Rubino Lianshen Wang Dazhuang Li Bofeng Ding Gan Li | 2015 | Family Medicine and Community Health2015，3，1： | 5 |
| 3 | Genomic Landscape of Non-Small Cell Lung Cancer in Smokers and Never-Smokers显示文摘 | Ramaswamy Govindan Li Ding Malachi Griffith Janakiraman Subramanian Nathan D. Dees Krishna L. Kanchi Christopher A. Maher Robert Fulton Lucinda Fulton John Wallis Ken Chen Jason Walker Sandra McDonald Ron Bose David Ornitz Donghai Xiong Ming You David J. | 2012 | Cell2012，，： | 1 |
| 4 | Mechanical properties and oxidation resistance of SiCf/CVI-SiC com- posites with PIP-SiC interphase 显示文摘 | Donghai Ding Wancheng Zhou Fa Luo | 2012 | Ceramics Internation- al2012，38，： | 1 |
| 5 | Complex permittivity and microwave absorbing properties of SiC fiber woven fabries显示文摘 | DING Donghai ZHOU Wancheng ZHANG Biao | 2011 | Journal of Materials Science2011，46，8： | 1 |
| 6 | Genomic Landscape of Non-Small Cell Lung Cancer in Smokers and Never-Smokers显示文摘 | Ramaswamy Govindan Li Ding Malachi Griffith Janakiraman Subramanian Nathan D. Dees Krishna L. Kanchi Christopher A. Maher Robert Fulton Lucinda Fulton John Wallis Ken Chen Jason Walker Sandra McDonald Ron Bose David Ornitz Donghai Xiong Ming You David J. | 2012 | Cell2012，，6： | 1 |
| 7 | Mechanical properties and oxidation resistance of SiC f /CVI-SiC composites with PIP-SiC interphase显示文摘 | Donghai Ding Wancheng Zhou Fa Luo Malin Chen Dongmei Zhu | 2012 | Ceramics International2012，，5： | 1 |
| 8 | Dip-coating of boron nitride interphase and its effects on mechanical properties of SiC f /SiC composites显示文摘 | Donghai Ding Wancheng Zhou Fa Luo Malin Chen Dongmei Zhu | 2012 | Materials Science & Engineering A2012，，： | 1 |
| 9 | The effects of CVD SiC interphase on mechanical properties of KD-1 SiC fiber reinforced aluminum phosphate composites显示文摘 | Donghai Ding Wancheng Zhou Fa Luo Yang Mu Dongmei Zhu | 2011 | Materials Science & Engineering A2011，，： | 1 |
| 10 | Effect of endoxylanases on dough properties and making performance of Chinese steamed bread显示文摘 | Dongmin Su Changhe Ding Lite Li Donghai Su Xinyu Zheng | 2005 | European Food Research and Technology (-)2005，，5： | 1 |
| 11 | Influence of pyrolytics carbon coatings on complex permittivity and mi?crowave absorbing properties of Al, 03 fiber woven fabrics显示文摘 | Ding Donghai Zhou Wancheng Luo Fa | 2012 | Trans Nonferrous Met Soc China2012，22，2： | 1 |
| 12 | Xenotime-type high-entropy(Dy_(1/7)Ho_(1/7)Er_(1/7)Tm_(1/7)Yb_(1/7)Lu_(1/7)Y_(1/7))PO_(4):A promising thermal/environmental barrier coating material for SiCf/SiC ceramic matrix composites显示文摘Rare-earth phosphates(REPO4)are regarded as one of the promising thermal/environmental barrier coating(T/EBC)materials for SiCf/SiC ceramic matrix composites(SiC-CMCs)owing to their excellent resistance to water vapor and CaO–MgO–Al_(2)O_(3)–SiO_(2)(CMAS).Nevertheless,a relatively high thermal conductivity(κ)of the REPO_(4) becomes the bottleneck for their practical applications.In this work,novel xenotime-type high-entropy(Dy_(1/7)Ho_(1/7)Er_(1/7)Tm_(1/7)Yb_(1/7)Lu_(1/7)Y_(1/7))PO4(HE(7RE_(1/7))PO_(4))has been designed and synthesized for the first time to solve this issue.HE(7RE_(1/7))PO_(4) with a homogeneous rare-earth element distribution exhibits high thermal stability up to 1750℃and good chemical compatibility with SiO_(2) up to 1400℃.In addition,the thermal expansion coefficient(TEC)of HE(7RE_(1/7))PO_(4)(5.96×10^(−6)℃^(−1) from room temperature(RT)to 900℃)is close to that of the SiC-CMCs.What is more,the thermal conductivities of HE(7RE_(1/7))PO_(4)(from 4.38 W·m^(−1)·K^(−1) at 100℃to 2.25 W·m^(−1)·K^(−1) at 1300℃)are significantly decreased compared to those of single-component REPO4 with the minimum value ranging from 9.90 to 4.76 W·m^(−1)·K^(−1).These results suggest that HE(7RE_(1/7))PO_(4) has the potential to be applied as the T/EBC materials for the SiC-CMCs in the future. | Peixiong Zhang Xingjun Duan Xiaochang Xie Donghai Ding Tao Yang Xinmei Hou Yunsong Zhao Enhui Wang | 2023 | Journal of Advanced Ceramics2023，12，5： | 1 |
| 13 | New aromatic substituted pyrazoles as selective inhibitors of human adipocyte fatty acid-binding protein显示文摘 | Xiujie Liu Xiaoli Huang Wanhua Lin Dongye Wang Yanyan Diao Honglin Li Xiaoyan Hui Yu Wang Aimin Xu Donghai Wu Ding Ke | 2011 | Bioorganic & Medicinal Chemistry Letters2011，，10： | 1 |
| 14 | Low - melting - point biodiesel derived from corn oil via urea complexation 显示文摘 | BI Yanlan DING Dongyou WANG Donghai | 2010 | Bioresour Technol2010，101，4： | 1 |
| 15 | Effects of Soil Hydraulic Properties on Soil Moisture Estimation显示文摘Accurate quantification of soil moisture is essential to understand the land surface processes.Soil hydraulic properties influence water transport in soil and thus affect the estimation of soil moisture.However,some soil hydraulic properties are only observable at a few field sites.In this study,the effects of soil hydraulic properties on soil moisture estimation are investigated by using the one-dimensional(1-D)Richards equation at ELBARA,which is part of the Maqu monitoring network over the Tibetan Plateau(TP),China.Soil moisture assimilation experiments are then conducted with the unscented weighted ensemble Kalman filter(UWEnKF).The results show that the soil hydraulic properties significantly affect soil moisture simulation.Saturated soil hydraulic conductivity(Ksat)is optimized based on its observations in each soil layer with a genetic algorithm(GA,a widely used optimization method in hydrology),and the 1-D Richards equation performs well using the optimized values.If the range of Ksat for a complete soil profile is known for a particular soil texture(rather than for arbitrary layers within the horizon),optimized Ksat for each soil layer can be obtained by increasing the number of generations in GA,although this increases the computational cost of optimization.UWEnKF performs well with optimized Ksat,and improves the accuracy of soil moisture simulation more than that with calculated Ksat.Sometimes,better soil moisture estimation can be obtained by using optimized saturated volumetric soil moisture content Ksat.In summary,an accurate soil profile can be obtained by using soil moisture assimilation with optimized soil hydraulic properties. | Xiaolei FU Haishen LYU Zhongbo YU Xiaolei JIANG Yongjian DING Donghai ZHENG Jinbai HUANG Hongyuan FANG | 2023 | Journal of Meteorological Research2023，37，1： | 1 |
| 16 | Combustion Synthesis of C/MgAl_(2)O_(4)Composite Powders and Their Microstructure Evolution显示文摘This work aims at solving the problems of difficult dispersion,easy oxidation and high cost of nano carbon during application,carbon/magnesium aluminate spinel(C/MgAl_(2)O_(4))composite powders were prepared using MgC2O4·2H2O,MgO2,Al2O3 powder,and Al powder as raw materials by combustion synthesis.The results indicate that with the maximum MgC2O4·2H2O addition of 33.34 mass%,the prepared powder contains 1.17 mass%of carbon and carbon distributes among spinel grains.The MgAl_(2)O_(4)spinel shows both granular and rod-like morphologies.The granular MgAl_(2)O_(4)spinel is generated from mutual diffusion between MgO and Al2O3;while the rod-like MgAl_(2)O_(4)spinel is mainly formed by the vapor-solid growth mechanism from Mg vapor and Al2O3. | LYU Lihua DING Donghai XIAO Guoqing | 2021 | China's Refractories2021，30，4： | 0 |
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