|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Gastric mucin expression in Helicobacter pylori-related, nonsteroidal anti-inflammatory drug-related and idiopathic ulcers显示文摘AIM: To determine the pattern of secreted mucin expression in Helicobacter pylori (H. pylori)-related, nonsteroidal anti-inflammatory drug (NSAID)-related and idiopathic gastric ulcers. METHODS: We randomly selected 92 patients with H. pylori-associated (n = 30), NSAID-associated (n = 18), combined H. pylori and NSAID-associated gastric ulcers (n = 24), and patients with idiopathic gastric ulcers (n = 20). Immunohistochemistry for T-cell CD4/CD8, andfor mucin 5AC (MUC5AC) and mucin 6 (MUC6), was performed on sections of the mucosa from the ulcer margin. Inflammation score was assessed according to the Sydney system. RESULTS: MUC5AC was expressed on the surface epithelium (98.9%) and neck glands (98.9%) with minimal expression in the deep glands (6.5%). MUC6 was strongly expressed in the deep glands (97.8%), variable in the neck glands (19.6%) and absent in the surface epithelium (0%). The pattern of mucin expression in idiopathic ulcer margins was not different from the expression in ulcers associated with H. pylori, NSAIDs, or combined H. pylori and NSAIDs. CD4/CD8 ratio was higher in H. pylori-positive patients (P = 0.009). Idiopathic ulcers are associated with hospitalized patients and have higher bleeding and mortality rates. CONCLUSION: Idiopathic ulcers have a unique clinical profile. Gastric mucin expression in idiopathic gastric ulcers is unchanged compared with H. pylori and/or NSAID-associated ulcers. | Doron Boltin Marisa Halpern Zohar Levi Alex Vilkin Sara Morgenstern Samuel B Ho Yaron Niv | 2012 | World Journal of Gastroenterology2012，18，33： | 5 |
| 2 | Membrane-bound mucins and mucin terminal glycans expression in idiopathic or Helicobacter pylori, NSAID associated peptic ulcers显示文摘AIM:To determine the expression of membrane-bound mucins and glycan side chain sialic acids in Helicobacter pylori(H.pylori)-associated,non-steroidal inflammatory drug(NSAID)-associated and idiopathic-gastric ulcers.METHODS:We studied a cohort of randomly selected patients with H.pylori(group 1,n=30),NSAID(group 2,n=18),combined H.pylori and NSAID associated gastric ulcers(group 3,n=24),and patients with idiopathic gastric ulcers(group 4,n=20).Immunohistochemistry for MUC1,MUC4,MUC17,and staining for Erythrina cristagalli agglutinin and Sambucus nigra agglutinin(SNA)lectins was performed on sections from the ulcer margins.RESULTS:Staining intensity of MUC17 was higher in H.pylori ulcers(group 1)than in idiopathic ulcers(group4),11.05±3.67 vs 6.93±4.00 for foveola cells,and10.29±4.67 vs 8.00±3.48 for gland cells,respectively(P<0.0001).In contrast,MUC1 expression was higher in group 4 compared group 1,9.89±4.17 vs 2.93±5.13 in foveola cells and 7.63±4.60 vs 2.57±4.50 for glands,respectively(P<0.0001).SNA lectin staining was increased in group 4,in parallel to elevated MUC1expression,indicating more abundantα2-6 sialylation in that group.CONCLUSION:Cytoplasmic MUC17 staining was sig-nificantly decreased in the cases with idiopathic ulcer.The opposite was observed for both MUC1 and SNA lectin.This observation may reflect important pathogenic mechanisms,since different mucins with altered sialylation patterns may differ in their protection efficiency against acid and pepsin. | Yaron Niv Doron Boltin Marisa Halpern Miriam Cohen Zohar Levi Alex Vilkin Sara Morgenstern Vahig Manugian Erica St Lawrence Pascal Gagneux Sukhwinder Kaur Poonam Sharma Surinder K Batra Samuel B Ho | 2014 | World Journal of Gastroenterology2014，20，40： | 5 |
| 3 | Predicting accurate cathode properties of layered oxide materials using the SCAN meta-GGA density functional显示文摘Layered lithium intercalating transition metal oxides are promising cathode materials for Li-ion batteries.Here,we scrutinize the recently developed strongly constrained and appropriately normed(SCAN)density functional method to study structural,magnetic,and electrochemical properties of prototype cathode materials LiNiO_(2),LiCoO_(2),and LiMnO_(2) at different Li-intercalation limits.We show that SCAN outperforms earlier popular functional combinations,providing results in considerably better agreement with experiment without the use of Hubbard parameters,and dispersion corrections are found to have a small effect.In particular,SCAN fares better than Perdew–Burke–Ernzerhof(PBE)functional for the prediction of band-gaps and absolute voltages,better than PBE+U for the electronic density of states and voltage profiles,and better than both PBE and PBE+U for electron densities and in operando lattice parameters.This overall better performance of SCAN may be ascribed to improved treatment of localized states and a better description of short-range dispersion interactions. | Arup Chakraborty Mudit Dixit Doron Aurbach Dan T.Major | 2018 | npj Computational Materials2018，，1： | 4 |
| 4 | Microsurgical epididymal sperm aspiration: indications, techniques and outcomes显示文摘Microsurgical epididymal 精子渴望(方山) 从被选择并且取样了使用一台操作显微镜提供的高力量的光放大的 epididymis 的最佳的区域指包含精子的液体的检索。检索精子随后被使用让 intracytoplasmic 精子注射(ICSI ) 导致授精和怀孕。方山被是为在有给它复杂并发症的优秀精子,优秀报导授精和怀孕率,和低风险的高收益的妨碍的精子缺乏的人的精子检索的标准答案技术的许多专家考虑。然而,方山必须在一个操作房间里被执行,要求 microsurgical 技巧并且为用 ICSI 的复制仅仅是有用的。此处我们在场为方山,过程的技术表演和被报导了的结果的候选人病人的评估的概述。 | Aaron M Bernie Ranjith Ramasamy Doron S Stember Peter J Stahl | 2013 | Asian Journal of Andrology2013，15，1： | 4 |
| 5 | Erdheim chester-A rare disease with unique endoscopic features显示文摘Erdheim-Chester disease(ECD) is a rare inflammatory syndrome in which systemic infiltration of non-Langerhans cell histiocytes occurs in different sites. Both the etiology and pathophysiology of ECD are unknown, but CD68 positive CD 1a/S100 negative cells are characteristic. The presentation of ECD differs according to the involved organs. This case report describes a patient with ECD and the gastrointestinal manifestations and unique endoscopic appearance as seen in gastroscopy and colonoscopy with histological proof of histiocyte infiltration of the lamina propria. The clinical and endoscopic findings of this unique case, to our knowledge, were never described before, so were the features of the gastrointestinal involvement in this disease. | Gil Ben-yaakov Daniela Munteanu Ignacio Sztarkier Alexer Fich Doron Schwartz | 2014 | World Journal of Gastroenterology2014，20，25： | 3 |
| 6 | High on food: the interaction between the neural circuits for feeding and for reward显示文摘饥饿,主要在精力由缺乏开始了,导致寻求的食物和吸入。然而,向食物的开车是不仅由生理的需要调整了,而且被从食物的摄取导出的快乐激发,特别地好吃的食物。因此,喂被看作包含在喂电路和报酬电路的 homeostatic 之间的综合通讯的适应激发的行为。一个喂的事件的开始和结束被许多 neuronal 信号,和不适应的粘性在几乎任何东西指示网络的部件可以导致病理学的吃的混乱的开发。在这评论,我们将总结在大脑的喂的电路和报酬电路怎么交往的最近的理解。我们将强调在视下丘和 mesolimbic 多巴胺系统之间的通讯并且为这块地加亮复杂性,差异,待研究的问题和未来方向。 | Jing-Jing Liu Diptendu Mukherjee Doron Haritan Bogna Ignatowska-Jankowska Ji Liu Ami Citri Zhiping P. Pang | 2015 | Frontiers in Biology2015，10，2： | 3 |
| 7 | Combination of corticosteroids and 5-aminosalicylates or corticosteroids alone for patients with moderate-severe active ulcerative colitis:A global survey of physicians'practice显示文摘AIM To examine treatment decisions of gastroenterologists regarding the choice of prescribing 5-aminosalycilates(5ASA) with corticosteroids(CS) versus corticosteroids alone for patients with active ulcerative colitis(UC). METHODS A cross-sectional questionnaire exploring physicians' attitude toward 5ASA + CS combination therapy vs CS alone was developed and validated. The questionnaire was distributed to gastroenterology experts in twelve countries in five continents. Respondents' agreement with stated treatment choices were assessed by standardized Likert scale. Background professional characteristics of respondents were analyzed for correlation with responses. RESULTS Six hundred and sixty-four questionnaires were distributed and 349 received(52.6% response rate). Of 340 eligible respondents, 221(65%) would continue 5ASA in a patient hospitalized for intravenous CS treatment due to a moderate-severe UC flare, while 108(32%) would stop the 5ASA(P < 0.001), and 11(3%) are undecided. Similarly, 62% would continue 5ASA in an out-patient starting oral CS. However, only 140/340(41%) would proactively start 5ASA in a hospitalized patient not receiving 5ASA before admission. Most(94%) physicians consider the safety profile of 5ASA as very good. Only 52% consider them inexpensive, 35% perceive them to be expensive and 12% are undecided. On multi-variable analysis, less years of practice and perception of a plausible additive mechanistic effect of 5ASA + CS were positively associated with the decision to continue 5ASA with CS. CONCLUSION Despite the absence of data supporting its benefit, most gastroenterologists endorse combination of 5ASA + CS for patients with active moderate-to-severe UC. Randomized controlled trials are needed to assess if 5ASA confer any benefit for these patients. | Shomron Ben-Horin Jane M Andrews Konstantinos H Katsanos Florian Rieder Flavio Steinwurz Konstantinos Karmiris Jae Hee Cheon Gordon William Moran Monica Cesarini Christian D Stone Doron Schwartz Marijana Protic Xavier Roblin Giulia Roda Min-Hu Chen Ofir Har-Noy Charles N Bernstein | 2017 | World Journal of Gastroenterology2017，23，16： | 3 |
| 8 | A Variational Framework for Retinex显示文摘 | Ron Kimmel Michael Elad Doron Shaked Renato Keshet Irwin Sobel | 2003 | International Journal of Computer Vision2003，，1： | 3 |
| 9 | Wireless capsule video endoscopy is a superior diagnostic tool in comparison to barium follow-through and computerized tomography in patients with suspected Crohn’s disease显示文摘 | Rami Eliakim Doron Fischer Alain Suissa Kamal Yassin Dalia Katz Nurit Guttman Michal Migdal | 2003 | European Journal of Gastroenterology & Hepatology2003，，4： | 3 |
| 10 | Liquid marbles containing petroleum and their properties显示文摘Liquid marbles(non-stick droplets) containing crude petroleum are reported.Liquid marbles were obtained by use of fluorinated decyl polyhedral oligomeric silsequioxane(FD-POSS) powder.Marbles containing crude petroleum remained stable on a broad diversity of solid and liquid supports.The effective surface tension of marbles filled with petroleum was established.The mechanism of friction of the marbles is discussed.Actuation of liquid marbles containing crude petroleum with an electric field is presented. | Edward Bormashenko Roman Pogreb Revital Balter Hadas Aharoni Doron Aurbach Vladimir Strelnikov | 2015 | Petroleum Science2015，12，2： | 2 |
| 11 | Potential mechanisms promoting restenosis in diabetic patients显示文摘 | Doron Aronson Zachary Bloomgarden Elliot J. Rayfield | 1996 | Journal of the American College of Cardiology1996，，3： | 2 |
| 12 | Hydrotropism: Root Bending Does Not Require Auxin Redistribution显示文摘 | Doron Shkolnik Gat Krieger Roye Nuriel Hillel Fromm | 2016 | Molecular Plant2016，9，5： | 2 |
| 13 | Ratio Analysis and Equity Valuation: From Research to Practice显示文摘 | Doron Nissim Stephen H. Penman | 2001 | Review of Accounting Studies2001，，1： | 2 |
| 14 | Management of ejaculatory disorders in infertile men显示文摘射精的机能障碍是可以沿着从早泄(PE )的连续统被分类的一个高度流行的临床的条件,通过延迟或推迟的射精(DE ) ,到完全的 anejaculation (AE ) 。后退射精(RE ) 表示在哪个射精的一个不同实体部分或完全被驱逐进膀胱。当 DE 和 PE 是在人和他们的搭挡之中的性不满的重要来源时,有这些混乱的病人在大多数情况中保留正常富饶。相反地,有 AE 和 RE 的人是不能的交付精子进女生殖道并且是因此显示的 subfertile。在考察他们联系到生育力的射精的混乱,因此,这份报纸将首先集中于 AE 和 RE 的诊断和管理。生理学,诊断策略,药理学治疗,和与 AE 和 RE 相关的程序的干预被讨论。 | Yagil Barazani Peter J Stahl Harris M Nagler Doron S Stember | 2012 | Asian Journal of Andrology2012，14，4： | 2 |
| 15 | Agile patency system eliminates risk of capsule retention in patients with known intestinal strictures who undergo capsule endoscopy显示文摘 | Juan M. Herrerias Jonathan A. Leighton Guido Costamagna Anthony Infantolino Rami Eliakim Doron Fischer David T. Rubin Howard D. Manten Eitan Scapa Douglas R. Morgan Ari J. Bergwerk Binyamin Koslowsky Samuel N. Adler | 2008 | Gastrointestinal Endoscopy2008，，6： | 2 |
| 16 | Probiotics for Prevention of Antibiotic-associated Diarrhea显示文摘 | Shira Idit Doron Patricia L. Hibberd Sherwood L. Gorbach | 2008 | Journal of Clinical Gastroenterology2008，，： | 2 |
| 17 | The effect of correction of mild anemia in severe, resistant congestive heart failure using subcutaneous erythropoietin and intravenous iron: a randomized controlled study显示文摘 | Donald S Silverberg Dov Wexler David Sheps Miriam Blum Gad Keren Ron Baruch Doron Schwartz Tatyana Yachnin Shoshana Steinbruch Itzhak Shapira Shlomo Laniado Adrian Iaina | 2001 | Journal of the American College of Cardiology2001，，7： | 2 |
| 18 | Coherent Wide-Band Processing for Arbitrary Array Geometry 显示文摘 | Doron M A Doron E Weissa J | 1993 | IEEE Trans on SP1993，41，5： | 1 |
| 19 | Capsule endoscopy: the localization system显示文摘 | Doron Fischer Reuven Schreiber Daphna Levi Rami Eliakim | 2004 | Gastrointestinal Endoscopy Clinics of North Americ2004，，1： | 1 |
| 20 | Probioties for prevention of an- tibiotic-associated diarrhea 显示文摘 | Doron SI Hibberd PL Gorbaeh SL | 2008 | J Clin Gastroenterol2008，42，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员