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| 1 | Sessile serrated adenomas:Demographic,endoscopic and pathological characteristics显示文摘AIM:To study the demographic and endoscopic characteristics of patients with sessile serrated adenoma(SSA) in a single center.METHODS:Patients with SSA were identified by review of the pathology database of Mayo Clinic Arizona from 2005 to 2007.A retrospective chart review was performed to extract data on demographics,polyp characteristics,presence of synchronous adenomatous polyps or cancer,polypectomy methods,and related complications.RESULTS:One hundred and seventy-one(2.9%) of all patients undergoing colonoscopy had a total of 226 SSAs.The mean(SE) size of the SSAs was 8.1(0.4) mm;42% of SSAs were ≤ 5 mm,and 69% were ≤ 9 mm.Fifty-one per cent of SSAs were located in the cecum or ascending colon.Approximately half of the patients had synchronous polyps of other histological types,including hyperplastic and adenomatous polyps.Synchronous adenocarcinoma was present in seven(4%) cases.Ninety-seven percent of polyps were removed by colonoscopy.CONCLUSION:Among patients with colon polyps,2.9% were found to have SSAs.Most of the SSAs were located in the right side and were safely managed by colonoscopy. | Suryakanth R Gurudu Russell I Heigh Giovanni De Petris Evelyn G Heigh Jonathan A Leighton Shabana F Pasha Isaac B Malagon Ananya Das | 2010 | World Journal of Gastroenterology2010，16，27： | 7 |
| 2 | Capsule endoscopy in suspected small bowel Crohn's disease:Economic impact of disease diagnosis and treatment显示文摘AIM: To model clinical and economic benef its of capsule endoscopy (CE) compared to ileo-colonoscopy and small bowel follow-through (SBFT) for evaluation of suspected Crohn’s disease (CD). METHODS: Using decision analytic modeling, total and yearly costs of diagnostic work-up for suspected CD were calculated, including procedure-related adverse events, hospitalizations, off ice visits, and medications. The model compared CE to SBFT following ileo-colonoscopy and secondarily compared CE to SBFT for initial evaluation. RESULTS: Aggregate charges for newly diagnosed, medically managed patients are approximately $8295. Patients requiring aggressive medical management costs are $29 508; requiring hospitalization, $49 074. At sensitivity > 98.7% and specifi city of > 86.4%, CE is less costly than SBFT. CONCLUSION: Costs of CE for diagnostic evaluationof suspected CD is comparable to SBFT and may be used immediately following ileo-colonoscopy. | Jonathan A Leighton Ian M Gralnek Randel E Richner Michael J Lacey Frank J Papatheofanis | 2009 | World Journal of Gastroenterology2009，15，45： | 5 |
| 3 | Nat Med:靶向两分子或有助于彻底治愈白血病显示文摘科学家在癌细胞内发现两个信号蛋白能够让癌细胞抵抗化疗。研究表明阻断这两种蛋白能够增强化疗对人类白血病小鼠模型的治疗效果。相关研究结果发表在国际学术期刊NatureMedicine上。研究人员发现在治疗中阻断c-Fos和Dusp1这两个蛋白能够治愈一些受激酶驱动且抵抗治疗的白血病和实体瘤。 | Meenu Kesarwani, Zachary Kincaid, Ahmed Gomaa, Erika Huber, Sara Rohrabaugh, Zain Siddiqui, Muhammad F Bouso, Kakajan Komurov, James C Mulloy, Jose A Cancelas, H Leighton Grimes Mohammad Azam Tahir Latif Ming Xu H Leighton Grimes Mohammad Azam | 2017 | 现代生物医学进展2017，17，17： | 4 |
| 4 | Relapse of Inflammatory Bowel Disease Associated With Use of Nonsteroidal Anti-Inflammatory Drugs显示文摘 | Angela M. Meyer Nizar N. Ramzan Russell I. Heigh Jonathan A. Leighton | 2006 | Digestive Diseases and Sciences2006，，： | 3 |
| 5 | Secure Spread Spectrum Watermarking for Multimedia显示文摘 | Cox I J Kilian J Leighton F T | | 0，，： | 3 |
| 6 | Epidural Labor Analgesia and the Incidence of Cesarean Delivery for Dystocia显示文摘 | Steven T. Fogel Jaye M. Shyken Barbara L. Leighton Jeffery S. Mormol James S. Smeltzer | 1998 | Anesthesia & Analgesia1998，，1： | 3 |
| 7 | ASGE guideline: the role of endoscopy in the surveillance of premalignant conditions of the upper GI tract显示文摘 | William K. Hirota Marc J. Zuckerman Douglas G. Adler Raquel E. Davila James Egan Jonathan A. Leighton Waqar A. Qureshi Elizabeth Rajan Robert Fanelli Jo Wheeler-Harbaugh Todd H. Baron Douglas O. Faigel | 2006 | Gastrointestinal Endoscopy2006，，4： | 2 |
| 8 | A multicenter, prospective, randomized comparison of a novel signal transmission capsule endoscope to an existing capsule endoscope显示文摘 | Eric H. Choi Klaus Mergener Carol Semrad Laurel Fisher David R. Cave Milan Dodig Carol Burke Jonathan A. Leighton David Kastenberg Peter Simpson James Sul Kanishka Bhattacharya Roger Charles Lauren Gerson Luke Weber Glenn Eisen Warren Reidel John J. Vargo | 2013 | Gastrointestinal Endoscopy2013，，2： | 2 |
| 9 | Double Balloon Enteroscopy Detects Small Bowel Mass Lesions Missed by Capsule Endoscopy显示文摘 | Andrew Ross Shahab Mehdizadeh Jeffrey Tokar Jonathan A. Leighton Ahmad Kamal Ann Chen Drew Schembre Gary Chen Kenneth Binmoeller Richard Kozarek Irving Waxman Charles Dye Lauren Gerson M. Edwyn Harrison Oleh Haluszka Simon Lo Carol Semrad | 2008 | Digestive Diseases and Sciences2008，，8： | 2 |
| 10 | What is the learning curve associated with double-balloon enteroscopy? Technical details and early experience in 6 U.S. tertiary care centers <ce:link locator='fx1'/>显示文摘 | Shahab Mehdizadeh Andrew Ross Lauren Gerson Jonathan Leighton Ann Chen Drew Schembre Gary Chen Carol Semrad Ahmad Kamal Edwyn M. Harrison Kenneth Binmoeller Irving Waxman Richard Kozarek Simon K. Lo | 2006 | Gastrointestinal Endoscopy2006，，5： | 2 |
| 11 | ASGE Guideline: the role of endoscopy in the patient with lower-GI bleeding显示文摘 | Raquel E. Davila Elizabeth Rajan Douglas G. Adler James Egan William K. Hirota Jonathan A. Leighton Waqar Qureshi Marc J. Zuckerman Robert Fanelli Jo Wheeler-Harbaugh Todd H. Baron Douglas O. Faigel | 2005 | Gastrointestinal Endoscopy2005，，： | 2 |
| 12 | Secure spread spectrum watermarking for multimedia显示文摘 | Cox I J Kilian J Leighton F T | 1997 | IEEE Trans on Image Processing1997，6，12： | 2 |
| 13 | Capsule Endoscopy in Patients with Implantable Electromedical Devices is Safe显示文摘 | Lucinda A. Harris Stephanie L. Hansel Elizabeth Rajan Komandoor Srivathsan Robert Rea Michael D. Crowell David E. Fleischer Shabana F. Pasha Suryakanth R. Gurudu Russell I. Heigh Arthur D. Shiff Janice K. Post Jonathan A. Leighton Hsu Heng Yen | 2013 | Gastroenterology Research and Practice2013，，： | 2 |
| 14 | Complications Associated With Double Balloon Enteroscopy at Nine US Centers显示文摘 | Lauren B. Gerson Jeffrey Tokar Michael Chiorean Simon Lo G. Anton Decker David Cave Doumit BouHaidar Daniel Mishkin Charles Dye Oleh Haluszka Jonathan A. Leighton Alvin Zfass Carol Semrad | 2009 | Clinical Gastroenterology and Hepatology2009，，11： | 2 |
| 15 | Double-Balloon Enteroscopy and Capsule Endoscopy Have Comparable Diagnostic Yield in Small-Bowel Disease: A Meta-Analysis显示文摘 | Shabana F. Pasha Jonathan A. Leighton Ananya Das M. Edwyn Harrison G. Anton Decker David E. Fleischer Virender K. Sharma | 2008 | Clinical Gastroenterology and Hepatology2008，，6： | 2 |
| 16 | Secure spread spectrum watermarking for multimedia显示文摘 | Cox I J Kilian J Leighton T Shamoon T | | 0，，： | 2 |
| 17 | Secure spread spectrum watermarking for multimedia显示文摘 | Cox I J Kilian J Leighton F T | 1997 | IEEE Trans on Image Processing1997，6，12： | 2 |
| 18 | Agile patency system eliminates risk of capsule retention in patients with known intestinal strictures who undergo capsule endoscopy显示文摘 | Juan M. Herrerias Jonathan A. Leighton Guido Costamagna Anthony Infantolino Rami Eliakim Doron Fischer David T. Rubin Howard D. Manten Eitan Scapa Douglas R. Morgan Ari J. Bergwerk Binyamin Koslowsky Samuel N. Adler | 2008 | Gastrointestinal Endoscopy2008，，6： | 2 |
| 19 | Double-Balloon Enteroscopy and Capsule Endoscopy Have Comparable Diagnostic Yield in Small-Bowel Disease: A Meta-Analysis显示文摘 | Shabana F. Pasha Jonathan A. Leighton Ananya Das M. Edwyn Harrison G. Anton Decker David E. Fleischer Virender K. Sharma | 2008 | Clinical Gastroenterology and Hepatology2008，，6： | 2 |
| 20 | Secure spread spectrum watermarking for multimedia显示文摘 | COX I J KILLIAN J LEIGHTON T | | 0，，12： | 2 |
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