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| 1 | Re-Os dating of gold-bearing arsenopyrite of the Maoling gold deposit,Liaoning Province,Northeast China and its geological significance显示文摘The Maoling gold deposit, one of the large gold deposits in eastern Liaoning Province, NE China, is an ar- senopyrite-disseminated gold deposit with a resource of ap- proximately 25 t Au and an average Au grade of 3.2 g/t. Six arsenopyrites closely related to Au mineralization of the Maoling gold deposit are dated by Re-Os technique and de- fine a Re-Os isochron with an age of 2316±140 Ma, which suggests that the deposit was formed in the Paleoproterozoic era rather than in the Indosinian period as some early re- searchers suggested. High initial 187Os/188Os ratio of 1.32±0.48 indicates a crustal derivation of the ore-forming material of the deposit, which may be derived from rocks of the Gaixian formation of the Liaohe Group. Furthermore, the result also implies that the age of the Gaixian Formation in the Maoling district is older than 2316±140 Ma. | YU Gang YANG Gang CHEN Jiangfeng QU Wenjun DU Andao HE Wei | 2005 | Chinese Science Bulletin2005，50，14： | 12 |
| 2 | Optimizing ultrasensitive single electron magnetometer based on nitrogen-vacancy center in diamond显示文摘The measurement of the weak magnetic field in nanoscale resolution and at room temperature is always a significant topic in biological, physical, and material science. Such detection can be used to decide the characterization of the samples, such as cells, materials, and so on. Nitrogen-vacancy (NV) center in diamond has been proved to be able to detect a magnetic field with nano Tesla sensitivity and nanometer resolution at room temperature. Here we experimentally demonstrate an optimized NV center based single electron magnetometer in a commercial diamond and under a home-built optically detected magnetic resonance (ODMR) microscope. With current technology, we change the optically detected time window to get a better signal to noise ratio, and use dynamical decoupling to increase the slope of magnetic field amplitude versus fluorescence signal. By employing the 8-pulse XY-4 dynamical decoupling sequence we achieve a sensitivity of 18.9 nT (Hz)(1/2) , which is 1.7 times better than spin echo. We also propose a NV center based scanning diamond microscope for electron and nuclear spins detection as well as nanoscale magnetic resonance imaging. If it is realized, the NV center based magnetometry will have wide application in the future. | WANG PengFei JU ChenYong SHI FaZhan DU JiangFeng | 2013 | Chinese Science Bulletin2013，58，24： | 5 |
| 3 | Blocking of the PD-1/PD-L1 interaction by a novel cyclic peptide inhibitor for cancer immunotherapy显示文摘The interaction of PD-1/PD-L1 allows tumor cells to escape from immune surveillance.Clinical success of the antibody drugs has proven that blockade of PD-1/PD-L1 pathway is a promising strategy for cancer immunotherapy.Here,we developed a cyclic peptide C8 by using Ph.D.-C7 C phage display technology.C8 showed high binding affinity with h PD-1 and could effectively interfere the interaction of PD-1/PD-L1.Furthermore,C8 could stimulate CD8^(+)T cell activation in human peripheral blood mononuclear cells(PBMCs).We also observed that C8 could suppress tumor growth in CT26 and B16-OVA,as well as anti-PD-1 antibody resistant B16 mouse model.CD8^(+)T cells infiltration significantly increased in tumor microenvironment,and IFN-γsecretion by CD8^(+)T cells in draining lymph nodes also increased.Simultaneously,we exploited T cells depletion models and confirmed that C8 exerted anti-tumor effects via activating CD8^(+)T cells dependent manner.The interaction model of C8 with h PD-1 was simulated and confirmed by alanine scanning.In conclusion,C8 shows anti-tumor capability by blockade of PD-1/PD-L1 interaction,and C8 may provide an alternative candidate for cancer immunotherapy. | Wenjie Zhai Xiuman Zhou Mingxia Zhai Wanqiong Li Yunhui Ran Yixuan Sun Jiangfeng Du Wenshan Zhao Lingxiao Xing Yuanming Qi Yanfeng Gao | 2021 | Science China(Life Sciences)2021，64，4： | 5 |
| 4 | Detection of radio-frequency field with a single spin in diamond显示文摘Detection of a.c. magnetic field is consequential for many developments in physical and biological sciences,and various designs of magnetometer have been proposed recently. However, the large size of sensor and the extreme measurement conditions required strongly limit their application. It remains a challenge to reconstruct the vector of a.c. field with nanoscale spatial resolution using a single spin under ambient conditions. In this work, we choose the radio-frequency(RF) field as a typical case and realize the measurement of RF field based on a nitrogen-vacancy(NV)center in diamond. We build a solid sensor through measuring the effect of RF field on NV electron spin energy levels and the transition between them. Both of the phase and amplitude(including the transverse and longitudinal components) are measured by this new approach. | Ying Liu Fei Kong Fazhan Shi Jiangfeng Du | 2016 | Science Bulletin2016，61，14： | 4 |
| 5 | Dynamical decoupling of electron spins in phosphorus-doped silicon显示文摘Quantum coherence is an important enabling feature underpinning quantum computation. However, because of couplings with its noisy surrounding environment, qubits suffer from the decoherence effects. The dynamical decoupling (DD) technique uses pulse-induced qubit flips to effectively mitigate couplings between qubits and environment. Optimal DD eliminates dephasing up to a given order with the minimum number of pulses. In this paper, we first introduce our recent work on prolonging electron spin coherence in γ-irradiated malonic acid crystals and analyze different decoherence mechanisms in this solid system. Then we focus on electron spin relaxation properties in another system, phosphorous-doped silicon (Si:P) crystals. These properties have been investigated by pulse electron paramagnetic resonance (EPR). We also investigate the performance of the dynamical decoupling technique on this system. Using 8-pulse periodic DD, the coherence time can be extended to 296 μs compared with 112 μs with one-pulse control. | RONG Xing WANG Ya YANG JiaHui ZHU JinXian XU WanJie FENG PengBo WEN XuJie SU JiHu DU JiangFeng | 2011 | Chinese Science Bulletin2011，56，7： | 4 |
| 6 | Synthesis and characterization of BiFeO_3 nanotube arrays and Y-junction BiFeO_3 nanotubes显示文摘Multiferroic BiFeO3 (BFO) nanotube arrays (~100 nm in diameter and ~50 μm in length) were synthesized by the sol-gel method utilizing the anodic aluminum oxide (AAO) membrane technique. The micro-structure and chemical components of the BFO nanotubes were investigated using scanning electron microscopy (SEM), transmission electron microscopy (TEM) and X-ray photoelectron spectrometer (XPS). The BFO nanotubes exhibited polycrystalline microstructures. The novel Y-junction BFO nano-tubes were simultaneously fabricated. | LI ChunYang LIU Bing ZHAO JianPo WANG JiangFeng HU BinBin DU ZuLiang | 2009 | Chinese Science Bulletin2009，54，5： | 3 |
| 7 | Prediction of sorghum miRNAs and their targets with computational methods显示文摘microRNAs 是 21-nt 的一个班在 post-transcriptional 起关键作用的长、非编码、最新识别的 RNA 基因规定。他们的目标涉及各种各样的生物过程,包括开发,新陈代谢,和压力反应。尽管很多 miRNAs 在许多种类被报导了,在蜀黍的 miRNAs 的报告是有限的。基于 genomic 调查顺序(GSS ) 和 microRNA (miRNA ) 使用相同搜索第二等的结构, 17 新 miRNAs 的一个总数在这个工作被识别。他们被发现在 11 个 miRNA 家庭之中不均匀的分布式。一些 miRNA 基因在多重地点并且在超过一 genomic 上下文被发现。大多数 miRNAs 在一样的王国以内被保存,但是我们在蜀黍发现 sbi-miR127 和 sbi-miR466 与 H 显示出保存。现代人并且 M。musculus 分别地。经由联机软件 miRU 的那些 17 新 miRNAs 的分析证明他们可能调整 64 目标基因,其大多数涉及 RNA 处理,新陈代谢,房间周期,蛋白质降级,压力反应和交通。11 个 miRNA 家庭中的至少 7 个指向在新陈代谢和压力反应是必要的蛋白质,包括 NADPH 细胞色素 P450 reductase, nucleoside diphosphate kinase 和 superoxide dismutase,建议 miRNAs 起在生物过程的一个必要作用。 | DU JiangFeng WU YongJun FANG XiaoFeng CAO JunXia ZHAO Liang TAO ShiHeng | 2010 | Chinese Science Bulletin2010，55，13： | 2 |
| 8 | Computational prediction and experimental verification of miRNAs in Panicum miliaceum L.显示文摘MicroRNAs (miRNAs) are a class of non-coding RNAs that play critical roles in post-transcriptional regulation. Their target genes are involved in a variety of biological processes such as development, metabolism, and stress response. Panicum miliaceum L. (Panicum) is an important grain crop, but, until now, no miRNAs have been identified in this plant. Using a homology search based on expressed sequence tag (EST) analysis and miRNA precursor secondary structure, a total of 43 new miRNAs were identified. The miRNAs were found to be unevenly distributed among 11 miRNA families. Target analysis using the plant small RNA target analysis server psRNATarget showed that the newly identified miRNAs can potentially regulate 68 target genes. Ten of the 11 miRNA families were annotated as involved in RNA regulation, suggesting they may play an essential role in post-transcriptional regulation in Panicum. Selected miRNAs representing eight of the families were verified by northern blotting, indicating that the prediction method that we used to identify the miRNAs was effective. | WU YongJun DU JiangFeng WANG XiaoLong FANG XiaoFeng SHAN WeiXing LIANG ZongSuo | 2012 | Science China(Life Sciences)2012，55，9： | 2 |
| 9 | Linear and nonlinear optical absorption coefficients and refractive index changes in asymmetrical Gaussian potential quantum wells with applied electric field显示文摘 | Aixin Guo Jiangfeng Du | 2013 | Superlattices and Microstructures2013，，： | 2 |
| 10 | 3D structural modeling integrated with seismic attribute and petrophysical evaluation for hydrocarbon prospecting at the Dhulian Oilfield,Pakistan显示文摘Surface and deep subsurface geological structural trends,stratigraphic features,and reservoir characteristics play important roles in assessment of hydrocarbon potential.Here,an approach that integrates digital elevation modelling,seismic interpretation,seismic attributes,three-dimensional(3D)geological structural modeling predicated on seismic data interpretation,and petrophysical analysis is presented to visualize and analyze reservoir structural trends and determine residual hydrocarbon potential.The digital elevation model is utilized to provide verifiable predictions of the Dhulian surface structure.Seismic interpretation of synthetic seismograms use two-way time and depth contour models to perform a representative 3D reservoir geological structure evaluation.Based on Petrel structural modeling efficiency,reservoir development indexes,such as the true 3D structural trends,slope,geometry type,depth,and possibility of hydrocarbon prospects,were calculated for the Eocene limestone Chorgali,upper Paleocene limestone Lockhart,early Permian arkosic sandstone Warcha,and Precambrian Salt Range formations.Trace envelope,instantaneous frequency,and average energy attribute analyses were utilized to resolve the spatial predictions of the subsurface structure,formation extrusion,and reflector continuity.We evaluated the average porosity,permeability,net to gross ratio,water saturation,and hydrocarbon saturation of early Eocene limestone and upper Paleocene limestone based on the qualitative interpretation of well log data.In summary,this integrated study validates 3D stratigraphic structural trends and fault networks,facilitates the residual hydrocarbon potential estimates,and reveals that the Dhulian area has a NE to SW(fold axis)thrust-bounded salt cored anticline structure,which substantiates the presence of tectonic compression.The thrust faults have fold axes trending from ENE to WSW,and the petrophysical analysis shows that the mapped reservoir is of good quality and has essential hydrocarbon potential,which can be exploited economically. | Umair KHAN Baoyi ZHANG Jiangfeng DU Zhengwen JIANG | 2021 | Frontiers of Earth Science2021，15，3： | 2 |
| 11 | Pulse-width-induced polarization enhancement of optically pumped N-V electron spin in diamond显示文摘The nitrogen-vacancy(N-V)center in diamond is a widely used platform for quantum information processing and sensing.The electron-spin state of the N-V center could be initialized,read out optically,and manipulated by resonate microwave fields.In this work,we analyze the dependence of electron-spin initialization on widths of laser pulses.We build a numerical model to simulate this process and to verify the simulation results in experiments.Both simulations and experiments reveal that shorter laser pulses are helpful to the electron-spin polarization.We therefore propose to use extremely short laser pulses for electron-spin initialization.In this new scheme,the spin-state contrast could be improved about 10%in experiments by using laser pulses as short as 4 ns in width.Furthermore,we provide a mechanism to explain this effect,which is due to the occupation time in the meta-stable spin-singlet states of the N-V center.Our new scheme is applicable in a broad range of N-V-based applications in the future. | YUMENG SONG YU TIAN ZHIYI HU FEIFEI ZHOU TENGTENG XING DAWEI LU BING CHEN YA WANG NANYANG XU JIANGFENG DU | 2020 | Photonics Research2020，8，8： | 1 |
| 12 | Entanglement playing a dominating role in quantum games 显示文摘 | Jiangfeng Du Xiaodong Xu Hui Li | 2001 | Physics Letters A2001，289，12： | 1 |
| 13 | Experimental realization of the quantum games on a computer显示文摘 | Jiangfeng Du Hui Li Xiaodong Xu | 2002 | Physical Re- view Letters2002，88，13： | 1 |
| 14 | A research on current collapse ofGaN HEMTs under DC high voltage显示文摘 | Long Fei Du Jiangfeng Luo Qian | | 0，，1： | 1 |
| 15 | Experimental demonstration of nonlinear quantum metrology with optimal quantum state显示文摘Nonlinear quantum metrology may exhibit better precision scalings. For example, the uncertainty of an estimated phase may scale as ??∝1/(N^2) under quadratic phase accumulation, which is 1/N times smaller than the linear counterpart, where N is probe number. Here, we experimentally demonstrate the nonlinear quantum metrology by using a spin-I(I > 1/2) nuclear magnetic resonance(NMR) ensemble that can be mapped into a system of N=2I spin-1/2 particles and the quadratic interaction can be utilized for the quadratic phase accumulation. Our experimental results show that the phase uncertainty can scale as ??∝1/(N^2-1)by optimizing the input states, when N is an odd number. In addition, the interferometric measurement with quadratic interaction provides a new way for estimating the quadrupolar coupling strength in an NMR system. Our system may be further extended to exotic nonlinear quantum metrology with higher order many-body interactions. | Xinfang Nie Jiahao Huang Zhaokai Li Wenqiang Zheng Chaohong Lee Xinhua Peng Jiangfeng Du | 2018 | Science Bulletin2018，63，8： | 1 |
| 16 | Experimental implementation of the quantum random-walk algorithm显示文摘 | Du Jiangfeng Li Hui Xu Xiaodong | 2003 | Physical Review A2003，67，4： | 1 |
| 17 | Carrier-envelope phase locking of 5 fs amplified Ti:sapphire laser pulse at 1 kHz repetition rate显示文摘This paper reports the carrier-envelop phase (CEP) locking for the 5 fs re-compressed laser pulse generated from a chirped pulse amplified (CPA) Ti:sapphire laser at 1 kHz repetition rate. A phase locking feedback system with two loops was designed to control the fast fluctuation arising from the seeding laser and the slow fluctuation arising from the sub-mJ amplified pulse. The principle and structure of the phase control system, including the CEP detection, servo loop design and phase locking result, are analyzed. The experiment shows that our phase locking system can be well used to establish the stable phase locking of few-cycle amplified laser pulse, and the CEP variation of below 53 mrad (rms) was demonstrated during a locking period of more than 3 h. | DU Qiang ZHU JiangFeng TENG Hao YUN ChenXia WEI ZhiYi | 2008 | Chinese Science Bulletin2008，53，5： | 1 |
| 18 | Myosin 1D and the branched actin network control the condensation of p62 bodies显示文摘Biomolecular condensation driven by liquid-liquid phase separation(LLPS)is key to assembly of membraneless organelles in numerous crucial pathways.It is largely unknown how cellular structures or components spatiotemporally regulate LLPS and condensate formation.Here we reveal that cytoskeletal dynamics can control the condensation of p62 bodies comprising the autophagic adaptor p62/SQSTM1 and poly-ubiquitinated cargos.Branched actin networks are associated with p62 bodies and are required for their conden satio n.Myosi n 1D,a bran ched acti n-associated motor protein,drives coalesce nee of small nano scale p62 bodies into large micron-scale condensates along the branched actin network.Impairment of actin cytoskeletal networks compromises the condensation of p62 bodies and retards substrate degradation by autophagy in both cellular models and Myosin ID knockout mice.Coupling of LLPS scaffold to cytoskeleton systems may represent a general mechanism by which cells exert spatiotemporal control over phase condensation processes. | Xuezhao Feng Wanqing Du Mingrui Ding Wenkang Zhao Xirenayi Xirefu Meisheng Ma Yuhui Zhuang Xiaoyu Fu Jiangfeng Shen Jinpei Zhang Xiuying Lei Daxiao Sun Qing Xi Yiliyasi Aisa Qian Chenr Ying Li Wenjuan Wang Shanjin Huang Li Yu Pilong Li Na Mi | 2022 | Cell Research2022，32，7： | 1 |
| 19 | Os-Os Dating Of Copper And Molybdenum Deposits Along The Middle And Lower Reaches of The Yangtze River,China显示文摘 | Sun Weidong Xie Zhi Chen Jiangfeng Zhang Xun Chai Zifang Du Andao Zhao Junshen Zhang henghuo Zhou Taofa | 2003 | Economic Geology2003，98，： | 1 |
| 20 | Functional tumor imaging based on inorganic nanomaterials显示文摘Inorganic nanomaterials have attracted substantial research interest due to their unique intrinsic physicochemical properties.We highlighted recent advances in the applications of inorganic nanoparticles regarding their imaging efficacy, focusing on tumor-imaging nanomaterials such as metal-based and carbon-based nanomaterials and quantum dots. Inorganic nanoparticles gain excellent in vivo tumor-imaging functions based on their specific characteristics of strong near-infrared optical absorption and/or X-ray attenuation capability. The specific response signals from these novel nanomaterials can be captured using a series of imaging techniques, i.e., optical coherence tomography(OCT), X-ray computed tomography(CT) imaging, two-photon luminescence(TPL), photoacoustic tomography(PAT), magnetic resonance imaging(MRI), surface-enhanced Raman scattering(SERS) and positron emission tomography(PET). In this review, we summarized the rapid development of inorganic nanomaterial applications using these analysis techniques and discussed the related safety issues of these materials. | Jiangfeng Du Xiao Zhang Liang Yan Rui Chen | 2017 | Science China Chemistry2017，60，11： | 1 |
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