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| 1 | High-density SNP-based genetic maps for the parents of an outcrossed and a selfed tetraploid garden rose cross, inferred from admixed progeny using the 68k rose SNP array显示文摘Dense genetic maps create a base for QTL analysis of important traits and future implementation of marker-assisted breeding.In tetraploid rose,the existing linkage maps include<300 markers to cover 28 linkage groups(4 homologous sets of 7 chromosomes).Here we used the 68k WagRhSNP Axiom single-nucleotide polymorphism(SNP)array for rose,in combination with SNP dosage calling at the tetraploid level,to genotype offspring from the garden rose cultivar‘Red New Dawn’.The offspring proved to be not from a single bi-parental cross.In rose breeding,crosses with unintended parents occur regularly.We developed a strategy to separate progeny into putative populations,even while one of the parents was unknown,using principle component analysis on pairwise genetic distances based on sets of selected SNP markers that were homozygous,and therefore uninformative for one parent.One of the inferred populations was consistent with self-fertilization of‘Red New Dawn’.Subsequently,linkage maps were generated for a bi-parental and a self-pollinated population with‘Red New Dawn’as the common maternal parent.The densest map,for the selfed parent,had 1929 SNP markers on 25 linkage groups,covering 1765.5 cM at an average marker distance of 0.9 cM.Synteny with the strawberry(Fragaria vesca)genome was extensive.Rose ICM1 corresponded to F.vesca pseudochromosome 7(Fv7),ICM4 to Fv4,ICM5 to Fv3,ICM6 to Fv2 and ICM7 to Fv5.Rose ICM2 corresponded to parts of F.vesca pseudochromosomes 1 and 6,whereas ICM3 is syntenic to the remainder of Fv6. | Mirjana Vukosavljev Paul Arens Roeland E Voorrips Wendy P C van't Westende G D Esselink Peter M Bourke Peter Cox W Eric van de Weg Richard G F Visser Chris Maliepaard Marinus J M Smulders | 2016 | Horticulture Research2016，3，1： | 6 |
| 2 | Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): a multicentre, randomised trial显示文摘 | David Sebag-Montefiore Richard J Stephens Robert Steele John Monson Robert Grieve Subhash Khanna Phil Quirke Jean Couture Catherine de Metz Arthur Sun Myint Eric Bessell Gareth Griffiths Lindsay C Thompson Mahesh Parmar | 2009 | The Lancet2009，，9666： | 5 |
| 3 | Axitinib plus gemcitabine versus placebo plus gemcitabine in patients with advanced pancreatic adenocarcinoma: a double-blind randomised phase 3 study显示文摘 | Hedy L Kindler Tatsuya Ioka Dirk J Richel Jaafar Bennouna Richard Létourneau Takuji Okusaka Akihiro Funakoshi Junji Furuse Young Suk Park Shinichi Ohkawa Gregory M Springett Harpreet S Wasan Peter C Trask Paul Bycott Alejandro D Ricart Sinil Kim Eric Van | 2011 | Lancet Oncology2011，，3： | 4 |
| 4 | Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial显示文摘 | Paul Y Kwo Eric J Lawitz Jonathan McCone Eugene R Schiff John M Vierling David Pound Mitchell N Davis Joseph S Galati Stuart C Gordon Natarajan Ravendhran Lorenzo Rossaro Frank H Anderson Ira M Jacobson Raymond Rubin Kenneth Koury Lisa D Pedicone Clifford | 2010 | The Lancet2010，，9742： | 3 |
| 5 | Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): a multicentre, randomised trial显示文摘 | David Sebag-Montefiore Richard J Stephens Robert Steele John Monson Robert Grieve Subhash Khanna Phil Quirke Jean Couture Catherine de Metz Arthur Sun Myint Eric Bessell Gareth Griffiths Lindsay C Thompson Mahesh Parmar | 2009 | The Lancet2009，，9666： | 3 |
| 6 | Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): a multicentre, randomised trial显示文摘 | David Sebag-Montefiore Richard J Stephens Robert Steele John Monson Robert Grieve Subhash Khanna Phil Quirke Jean Couture Catherine de Metz Arthur Sun Myint Eric Bessell Gareth Griffiths Lindsay C Thompson Mahesh Parmar | 2009 | The Lancet . 2009 (9666)2009，，9666： | 3 |
| 7 | Stereotactic body radiation therapy for management of spinal metastases in patients without spinal cord compression: a phase 1–2 trial显示文摘 | Xin Shelley Wang Laurence D Rhines Almon S Shiu James N Yang Ugur Selek Ibrahima Gning Ping Liu Pamela K Allen Syed S Azeem Paul D Brown Hadley J Sharp David C Weksberg Charles S Cleeland Eric L Chang | 2012 | Lancet Oncology2012，，4： | 2 |
| 8 | Characterization of tryp- tic casein phosphopeptides prepared under industrially relevant conditions显示文摘 | Adamson N J Reynolds Eric C | 1995 | Biotechnology and Bioengineering1995，45，3： | 1 |
| 9 | Development of a rapid automated influenza A, influenza B, and respiratory syncytial virus A/B multiplex real-time RT-PCR assay and its use during the 2009 H1N1 swine origin influenza virus epidemic in Milwaukee, Wisconsin显示文摘 | Eric T B Lisa A J Sue C K | 2010 | J Mol Diagn2010，12，： | 1 |
| 10 | Stress induced shift of the Curie point in epitaxial PbTiO3 thin films显示文摘 | GEORGE A ROSSETTI J ERIC C | 1991 | Appl Phy Lett1991，59，20： | 1 |
| 11 | Prevalence of colonic adenomas in average risk asymptomatic patients on daily aspirin显示文摘 | Nancy J Meier Shailesh C Kadakia | 1999 | Gastrointest Endosc1999，49，4： | 1 |
| 12 | Predictors of systolic and diastolic improvement in patients with dilated cardiomyopathy treated with metoprolol 显示文摘 | ERIC J E CHRISTIAN M H RICHARD C | 1995 | J Am coll cardiol1995，25，1： | 1 |
| 13 | The heat capacities of titanium sfiici6es TisSi3,TiSi and TiSi2 显示文摘 | Shilpa A Eric J C Sergei Z | | Journal of Aoys and Compounds0，314，： | 1 |
| 14 | An overview of existing methods and recent advances in sequential Monte Carlo显示文摘 | OLIVIER C SIMON J G ERIC M | 2007 | Proceedings of the IEEE2007，95，5： | 1 |
| 15 | An overview of existing methods and recent advances in sequential Monte Carlo显示文摘 | OLIVIER C SIMON J G ERIC M | 2007 | Proceedings of the IEEE2007，95，5： | 1 |
| 16 | Stress induced shift of the Curie point in epitaxial PbTiO3 thin films显示文摘 | GEORGE A ROSSETTI J ERIC C | 1991 | Appl Phy Lett1991，59，20： | 1 |
| 17 | A rise of ploidy level induces the expression of apomixis in Paspalum notatum 显示文摘 | Quarin C L Francisco E Eric J | 2001 | Sex Plant Reprod2001，13，5： | 1 |
| 18 | Pre concentration of benzalkonium chloride using sodium dodecyl sulfate attached to a strong anion exchange resin显示文摘 | KYLE A J ELIZABETH G V ERIC D C | 1999 | Functional Polymers1999，40，： | 1 |
| 19 | Dy∶YAG phosphor coating using the solution precursor plasma spray process显示文摘 | DIAN Y C ERIC H J MICHAEL W R | 2009 | Journal of the American Ceramic Society2009，92，1： | 1 |
| 20 | Electropolymerization of ferrocene bis-amide derivatives: a possible route to an electrochemical sensory device显示文摘 | Moutet J C Eric S A Ungureanu M | 1996 | Electroanal Chem1996，410，1： | 1 |
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