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| 1 | Football injuries of the ankle: A review of injury mechanisms, diagnosis and management显示文摘Football is the most popular sport worldwide and is associated with a high injury rate, most of which are the result of trauma from player contact. Ankle injuries are among the most commonly diagnosed injuries in the game. The result is reduced physical activity and endurance levels, lost game time, and considerable medical cost. Sports medicine professionals must employ the correct diagnostic tools and effective treatments and rehabilitation protocols to minimize the impact of these injuries on the player. This review examines the diagnosis, treatment, and postoperative rehabilitation for common football injuries of the ankle based on the clinical evidence provided in the current literature. | Raymond J Walls Keir A Ross Ethan J Fraser Christopher W Hodgkins Niall A Smyth Christopher J Egan James Calder John G Kennedy | 2016 | World Journal of Orthopedics2016，7，1： | 5 |
| 2 | MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressors显示文摘 | Liu Xi Sempere Lorenzo F Ouyang Haoxu Memoli Vincent A Andrew Angeline S Luo Yue Demidenko Eugene Korc Murray Shi Wei Preis Meir Dragnev Konstantin H Li Hua DiRenzo James Bak Mads Freemantle Sarah J Kauppinen Sakari Dmitrovsky Ethan | 2010 | Journal of Clinical Investigation2010，，4： | 3 |
| 3 | Low levels of high density lipoproteins in Turks, a population with elevated hepatic lipase:high density lipoprotein characterization and gender-specific effects of apolipoprotein E genotype显示文摘 | Mahley RW Pepin J Ethan PK | 2004 | J Lipiid Res2004，41，： | 1 |
| 4 | Abrogation of growth hormone secretion rescues fatty liver in mice with hepatocyte-specific deletion of JAK2显示文摘 | Sos Brandon C Harris Charles Nordstrom Sarah M Tran Jennifer L Balázs Mercedesz Caplazi Patrick Febbraio Maria Applegate Milana A B Wagner Kay-Uwe Weiss Ethan J | 2011 | Journal of Clinical Investigation2011，，4： | 1 |
| 5 | On estimating the exponent of power-law frequency distribution显示文摘 | Ethan P W Brian J E Jessica L G | 2008 | Ecology2008，89，4： | 1 |
| 6 | Mitochondrial H^sub 2^O^sub 2^ emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans显示文摘 | Anderson Ethan J Lustig Mary E Boyle Kristen E Woodlief Tracey L Kane Daniel A Lin Chien-Te Rice Jesse W Kang Li Rabinovitch Peter S Szeto Hazel H Houmard Joseph A Cortright Ronald N Wasserman David H Neufer P Darrell | 2009 | Journal of Clinical Investigation2009，，3： | 1 |
| 7 | Periprostatic administration of local anesthesia during transrectal ultrasound-guided biopsy of the prostate: a randomized, double-blind, placebo-controlled study显示文摘 | Andreas P Berger Ferdinand Frauscher Ethan J Halpern Robert Spranger Hannes Steiner Georg Bartsch Wolfgang Horninger | 2003 | Urology2003，，3： | 1 |
| 8 | National kidney foundation practice guidelines for chronic kidney disease显示文摘 | Levey AS Coresh J Ethan B | 2003 | Ann Intern Med2003，139，2： | 1 |
| 9 | Evalution of distributed recovery in large-scale storage system显示文摘 | Qin Xin Ethan L M Thomas J E | | 0，，： | 1 |
| 10 | Amplitude preservation of Radon- based multiple-removal filters 显示文摘 | Ethan J N Matthias G I | 2006 | Geophysics2006，71，5： | 1 |
| 11 | 显示文摘 | Ethan L G B | 1996 | Langmuir1996，12，： | 1 |
| 12 | Contrast-enhanced US of the prostate with sonazoid: comparison with whole-mount prostatectomy specimens in 12 patients显示文摘 | Ethan J Halpern Peter A McCue Anne K Aksnes | 2002 | Radiology2002，222，2： | 1 |
| 13 | Efficacy of botulinum tox- in A injection for neurogenic detrusor overactivity and urinary inconti- nence : a randomized, double-blind trim 显示文摘 | Herschorn S Gajewski J Ethans K | 2011 | J Urol2011，185，6： | 1 |
| 14 | Preoperative evaluation of living renal donors:comparison of CT angiography and MR angiography显示文摘 | Ethan J Halpern Donald G | 2000 | Radiology2000，216，2： | 1 |
| 15 | Efficacy of botulinum toxin A injection for neurogenic detrusor overactivity and urinary incontinence:a randomized, double- blind trial 显示文摘 | Herschorn S Gajewski J Ethans K | 2011 | The Journal of Urology2011，185，6： | 1 |
| 16 | Preoperative e valuation of living renal donocomparson of CT anography and MR anography 显示文摘 | Ethan J Halpem Donald G | 2000 | Radiology2000，216，2： | 1 |
| 17 | Efficacy of botulinum toxin A injection for neurogenic detrusor overactivity and urinary incontinence:a randomized,double-blind trial显示文摘 | Herschorn S Gajewski J Ethans K | | 0，，： | 1 |
| 18 | Spatially correlated anomalous ^40Ar/^39Ar 'age' variations in biotites about a lithologic contact near Simplon Pass, Switzerland: A mechanistic explanation for excess Ar显示文摘 | Ethan F B Donald J D Paul R R | 2002 | Geochim et Cosmochim Acta2002，66，： | 1 |
| 19 | Do Not Resuscitate status as an independent risk factor for patients undergoing surgery for hip fracture显示文摘AIM To determine morbidity and mortality in this specific patient group and also to assess for any independent associations between Do Not Resuscitate(DNR) status and increased post-operative morbidity and mortality.METHODS We conducted a propensity score matched retrospective analysis using de-identified data from the American College of Surgeons' National Surgical Quality Improvement Project(ACS NSQIP) for all patients undergoing hip fracture surgery over a 7 year period in hospitals across the United States enrolled in ACS NSQIP with and without Do Not Resuscitate Status. We measured patient demographics including DNR status, co-morbidities, frailty and functional baseline, surgical and anaestheticprocedure data, post-operative morbidity/complications, length of stay, discharge destination and mortality.RESULTS Of 9218 patients meeting the inclusion criteria, 13.6% had a DNR status, 86.4% did not. Mortality was higher in the DNR status compared to the non-DNR group, at 15.3% vs 8.1% and propensity score matched multivariable analysis demonstrated that DNR status was independently associated with mortality(OR = 2.04, 95%CI: 1.46-2.86, P < 0.001). Additionally, analysis of the propensity score matched cohort demonstrated that DNR status was associated with a significant, but very small increased likelihood of post-operative complications(0.53 vs 0.43 complications per episode; OR = 1.21; 95%CI: 1.04-1.41, P = 0.004). Cardiopulmonary resuscitation and unplanned reintubation were significantly less likely in patients with DNR status.CONCLUSION Whilst DNR status patients had higher rates of postoperative complications and mortality, DNR status itself was not otherwise associated with increased morbidity. DNR status appears to increase 30-d mortality via ceilings of care in keeping with a DNR status, including withholding reintubation and cardiopulmonary resuscitation. | Ethan Y Brovman Andrew J Pisansky Anair Beverly Angela M Bader Richard D Urman | 2017 | World Journal of Orthopedics2017，8，12： | 1 |
| 20 | Paroxetine vs pregabalin for the management of neuropathic pain in multiple sclerosis显示文摘AIM: To compare the effectiveness and tolerability of paroxetine vs pregabalin for the management of multiple sclerosis(MS)-induced neuropathic pain(NPP).METHODS: A randomized, flexible-dose open-label 8-wk study involving 21 relapsing-remitting MS patients with MS-induced NPP was conducted to evaluate the effectiveness and tolerability of pregabalin versus paroxetine for pain management. The trial included a 3-wk dose titration phase followed by a 5-wk stable dose phase. Primary outcome measures included daily patient-reported pain intensity as measured using a 100 mm visual analogue scale(VAS pain) and daily impact of pain on daily activities(VAS impact). Hierarchical regression modeling was conducted on each outcome to determine if within person VAS trajectory for pain and impact differed across study groups, during 56 d follow-up. RESULTS: Attrition rates were significantly greater(P < 0.001) in the paroxetine versus pregabalin study group(70% vs 18.2%, respectively). Average study duration between study groups also significantly differed(P < 0.001). Paroxetine participants completed an average of 27.3 d of treatment vs 49.5 d in the pregabalin group, with the majority of patients withdrawing due to adverse events. Due to the high attrition rates in the paroxetine study arm, the investigators stopped the study prior to achieving complete recruitment. As such, no significant differences between pregabalin and paroxetine study arms were noted for the primary outcome measures(VAS pain, VAS impact). Comparative assessment of baseline patient characteristics also revealed no significant differences between the study arms. CONCLUSION: High attrition rates associated with paroxetine use suggest that it be used with caution for MS-induced NPP. Efficacy outcomes could not be assessed due to attrition. | Dana A Turcotte Malcolm Doupe Mahmoud Torabi Andrew J Gomori Karen Ethans Farid Esfahani Katie Galloway Michael P Namaka | 2014 | World Journal of Anesthesiology2014，3，2： | 1 |
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