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| 1 | A study of miRNAs targets prediction and experimental validation显示文摘microRNAs(miRNAs)are 20–24 nucleotide(nt)RNAs that regulate eukaryotic gene expression post-transcriptionally by the degradation or translational inhibition of their target messenger RNAs(mRNAs).To identify miRNA target genes will help a lot by understanding their biological functions.Sophisticated computational approaches for miRNA target prediction,and effective biological techniques for validating these targets now play a central role in elucidating their functions.Owing to the imperfect complementarity of animal miRNAs with their targets,it is difficult to judge the accuracy of the prediction.Complexity of regulation by miRNA-mediated targets at protein and mRNAs levels has made it more challenging to identify the targets.To date,only a few miRNAs targets are confirmed.In this article,we review the methods of miRNA target prediction and the experimental validation for their corresponding mRNA targets in animals. | Yong Huang Quan Zou Haitai Song Fei Song Ligang Wang Guozheng Zhang Xingjia Shen | 2010 | Protein & Cell2010，1，11： | 7 |
| 2 | Coastal evolution of Yancheng, northern Jiangsu, China since the mid-Holocene based on the Landsat MSS imagery显示文摘自从 1970 年代,遥感图象为海岸线变化的描述和分析提供了新信息,特别集中于短 timescale 变化。基于 Landsat 女士形象,这份报纸集中于 Yancheng 的海岸线进化,北江苏,中国自从 mid-Holocene。一幅斑马条纹图象,能揭示 Yancheng 的古老的沿海的进化,从 Landsat 被提取女士图象。基于提取黑白人的条纹, 19 件表面沉积样品被恢复并且分析了认出这些条纹的沉积特征。它证明最,沙和淤泥的沙样品出现在白条纹上,当淤泥和淤泥的泥土样品在黑条纹上时。沙、泥泞的沉积在 Yancheng 沿海的平原上介绍一个轮流出现的分发模式。一张历史的海岸线地图根据 paleo 沿海的沙障碍和 paleo 海岸线的以前的研究成就被画,并且在斑马条纹图象上被附加。提取斑马条纹的趋势与历史的海岸线一致,并且它应该是 Yancheng 海岸线进化的标志。根据黑白人的条纹和以前的研究结果的十个集合,我们把 Yancheng 沿海的进化的前进划分了成三个阶段(即,早稳定的阶段( 6500 一BP广告 1128 ),快速的免职阶段(广告 11281855 )和调整阶段(广告1855礼品))。黑白人的条纹的十个集合在 Yancheng 沿海的平原上作为海岸线进化的典型模式被识别。 | KANG Yanyan XIA Fei DING Xianrong ZHANG Changkuan CHENG Ligang GE Xiaoping Jennifer GLASS | 2013 | Journal of Geographical Sciences2013，23，5： | 2 |
| 3 | The discovery of nanometer fringes in laser self-mixing interference显示文摘 | Ligang Fei Shulian Zhang | 2006 | Optics Communications2006，，1： | 2 |
| 4 | Experimental study on effects of moisture content on combustion characteristics of simulated municipal solid wastes in a fixed bed 显示文摘 | Liang Ligang Sun Rui Fei Jun | 2008 | Bioresource Technology2008，99，15： | 1 |
| 5 | Pay-it-forward gonorrhea and chlamydia testing among men who have sex with men in China:a study protocol for a three-arm cluster randomized controlled trial显示文摘Background:Gonorrhea and chlamydia testing rates are poor among Chinese men who have sex with men(MSM).A quasi-experimental study suggested that a pay-it-forward strategy increased dual gonorrhea/chlamydia testing among MSM.Pay-it-forward offers an individual a gift(e.g.,a free test)and then asks the same person if they would like to give a gift to another person.This article reports the protocol of a randomized controlled trial to evaluate dual gonorrhea/chlamydia test uptake and other outcomes among MSM in three arms-a pay-it-forward arm,a pay-what-you-want arm,and a standard of care arm.Methods:Three hundred MSM will be recruited at three HIV testing sites in Guangzhou and Beijing.Testing sites include two hospital-based MSM sexually transmitted diseases clinics and one MSM community-based organization.Eligible participants will be born biologically male,aged 16 years or older,reporting previous anal sex with another man,having never participated in the pay-it-forward program,without previous gonorrhea and chlamydia testing in the past 12 months,and residing in China.Following a cluster randomized design,every cluster of ten participants will be randomly allocated into one of three arms:(1)a pay-it-forward arm in which men are offered free gonorrhea and chlamydia testing and then asked whether they would like to donate('pay it forward')toward testing for future testers;(2)a pay-what-you-want arm in which men are offered free testing and told to decide how much to pay after receiving the test;(3)a standard of care arm in which men can pay the full price for dual gonorrhoea and chlamydia testing.The primary outcome is dual gonorrhoea/chlamydia testing as verified by administrative records.Secondary outcomes include incremental cost per test,incremental cost per diagnosis,community connectedness,and social cohesion.Primary outcome will be calculated for each arm using intention-to-treat and compared using one-sided 95%confidence intervals with a margin of 20%increase defined as superiority.Discussion:This study will examine the pay-it-forward strategy in comparison to the standard of care in improving test uptake for gonorrhea and chlamydia.We will leverage the cluster randomized controlled trial to provide scientific evidence on the potential effect of pay-it-forward.Findings from this study will shed light on novel intervention methods for increasing preventive health service utilization and innovate ways to finance it among communities.Trial registration:ClinicalTrials.gov,NCT03741725.Registered on 12 November 2018. | Tiange P.Zhang Fan Yang Weiming Tang Marcus Alexander Laura Forastiere Navin Kumar Katherine Li Fei Zou Ligang Yang Guodong Mi Yehua Wang Wenting Huang Amy Lee Weizan Zhu Peter Vickerman Dan Wu Bin Yang Nicholas A.Christakis Joseph D.Tucker | 2019 | Infectious Diseases of Poverty2019，8，4： | 1 |
| 6 | Experimental study on effects of moisture content on combustion characteristics of simulated municipal solid wastes in a fixed bed显示文摘 | Ligang Liang Rui Sun Jun Fei Shaohua Wu Xiang Liu Kui Dai Na Yao | 2007 | Bioresource Technology2007，，15： | 1 |
| 7 | Measurement of small intracavity phase anisotropy in a laser based on optical feedback显示文摘 | Ligang Fei Yan Li Xiaobin Zong Shulian Zhang | 2005 | Optics Communications2005，，1： | 1 |
| 8 | Intrusion-detection model integrating anomaly with misuse for space information network显示文摘In recent years,following the development of space commutation,space information has become a critical part in space information network and will play a very significant role in winning future information war.A space information network with characteristics such as complex structure,special communication requirement,long delay,dependence on remote maintenance,and fragile ecological environment contains enormous security risks.Therefore,ensuring space information network safety is important.Intrusion-detection model as an important part of a network security system becomes a hot issue in space network security.We propose an intrusion-detection method that integrates anomaly with misuse,which supports automatic updates from a remote ground,and design a distributed intrusion-detection model of space information network. | SHE Chundong MA Yaqi JIA Luting FEI Ligang KOU Baohua | 2016 | Journal of Communications and Information Networks2016，1，3： | 1 |
| 9 | Growth characteristics of Suaeda salsa under different soil salinity gradients in controlled experiments显示文摘Xinjiang is the province with the largest saline-alkali land in China.The growth of halophytes will be stressed when their salt content reaches the threshold.In this study,the pot experiments were conducted and Suaeda salsa,a typical halophyte,was selected as the object to explore the relationship between growth characteristics and salt content under different soil salinity gradients.Salinity gradients were set according to the maximum soil salinity in the current years of Ebinur Lake Wetland National Nature Reserve(ELWNNR).They were classified using the following threshold values:≤2 g/kg(Control Group),10 g/kg,20 g/kg,30 g/kg,and 40 g/kg.The original spectrum,trilateral position and growth characteristics were used as indexes for analysis.With the increase of soil salt content,the red edge shift occurs first,followed by the blue edge shift.The position of yellow edge,green peak and blue edge were not sensitive to the change of soil salinity.This indicates that the red edge is the best indicator for evaluating plant growth.Compared with the Control Group,when the salt content is less than 10 g/kg,the growth status of plant seems not significantly affected.However,plant growth begins to be stressed when the salt content increases to 20 g/kg,which is a turning point for plant health.The increase of soil salt content can inhibit chlorophyll synthesis and plant growth.Plants begin to die when the salt content reaches 40 g/kg.Therefore,40 g/kg could be regarded as the critical point of salt content which inhibits plant growth.The study also shows that the relationship between plant-height change rate and soil salt content is the most significant,indicating that the plant-height change rate is significantly impacted by soil salt content. | Fei Zhang Yun Chen Jie Yuan Ligang Ma Changjiang Liu | 2021 | International Journal of Agricultural and Biological Engineering2021，14，5： | 0 |
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