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| 1 | Identification of Hercynian shoshonitic intrusive rocks in central Hainan Island and its geotectonic implications显示文摘An identification has been made of some shoshonitic intrusive rocks in central Hainan Island recently. These rocks are K-rich (K2O=2.9%―5.1%, K2O/Na2O=0.95―2.12), distinctly enriched in LILE and LREE, strongly depleted in Nb, Ta, and moder- ately depleted in Sr and Ti, with (87Sr/86Sr)i = 0.70859―0.71425 and ε Nd(t) = (?2.77―?7.49). They were derived from an EMⅡ-type mantle source. The enrichment process is related to metasomatism of depleted mantle caused by a great amount of fluid-melt released from oceanic crust and terri- genous sediments at great depth (eclogite facies) during the subduction of the South China plate under the Indochina-South China Sea plate in the Carbon- iferous–Early Permian. A SHRIMP U-Pb zircon dating yields a crystallization age of 272±7 Ma for the sho- shonitic intrusions, which is coeval with the strongly peraluminous granites found in central Hainan Island. These two kinds of rocks generally possess syn-intrusion ductile deformation structures. Thus they are considered to have been generated during the early stage (syn-thrust phase) of a post-collisional event. The primary magma of shoshonitic rocks was produced at a depth > 80 km by decompression- dehydration melting of previously enriched litho- spheric mantle wedge, phlogopite-bearing garnet peridotite, which was in turn caused by the break-off of a descendent slab and upwelling of a hot as- thenosphere. The rising of melts was accompaniedby crustal contamination and crystallization fractiona- tion (AFC). Combining with other related data, it is proposed that the southwards subduction and amal- gamation of the South China plate with the Indo- China-South China Sea plate took place at ca. 287- 278 Ma, which was a part of the convergence proc- ess of the Pangea supercontinent. The suture zone was probably located along the line of Song Ma-Beibu Gulf-north margin of the Yunkai Moun- tains-Wuyi Mountains. | XIE Caifu ZHU Jinchu DING Shijiang ZHANG Yeming FU Tai'an LI Zhihong | 2006 | Chinese Science Bulletin2006，51，20： | 17 |
| 2 | Application of next-generation sequencing technology to precision medicine in cancer: joint consensus of the Tumor Biomarker Committee of the Chinese Society of Clinical Oncology显示文摘Next-generation sequencing(NGS) technology is capable of sequencing millions or billions of DNA molecules simultaneously.Therefore, it represents a promising tool for the analysis of molecular targets for the initial diagnosis of disease, monitoring of disease progression, and identifying the mechanism of drug resistance. On behalf of the Tumor Biomarker Committee of the Chinese Society of Clinical Oncology(CSCO) and the China Actionable Genome Consortium(CAGC), the present expert group hereby proposes advisory guidelines on clinical applications of NGS technology for the analysis of cancer driver genes for precision cancer therapy. This group comprises an assembly of laboratory cancer geneticists, clinical oncologists, bioinformaticians,pathologists, and other professionals. After multiple rounds of discussions and revisions, the expert group has reached a preliminary consensus on the need of NGS in clinical diagnosis, its regulation, and compliance standards in clinical sample collection. Moreover, it has prepared NGS criteria, the sequencing standard operation procedure(SOP), data analysis, report, and NGS platform certification and validation. | Xuchao Zhang Zhiyong Liang Shengyue Wang Shun Lu Yong Song Ying Cheng Jianming Ying Weiping Liu Yingyong Hou Yangqiu Li Yi Liu Jun Hou Xiufeng Liu Jianyong Shao Yanhong Tai Zheng Wang Li Fu Hui Li Xiaojun Zhou Hua Bai Mengzhao Wang You Lu Jinji Yang Wenzhao Zhong Qing Zhou Xuening Yang Jie Wang Cheng Huang Xiaoqing Liu Xiaoyan Zhou Shirong Zhang Hongxia Tian Yu Chen Ruibao Ren Ning Liao Chunyan Wu Zhongzheng Zhu Hongming Pan Yanhong Gu Liwei Wang Yunpeng Liu Suzhan Zhang Tianshu Liu Gong Chen Zhimin Shao Binghe Xu Qingyuan Zhang Ruihua Xu Lin Shen Yilong Wu | 2019 | Cancer Biology & Medicine2019，16，1： | 14 |
| 3 | Correlation between BRAF^(V600E) mutation and clinicopathological features in pediatric papillary thyroid carcinoma显示文摘In adults, the presence of the BRAF^(V600E) mutation in papillary thyroid cancer(PTC) has been demonstrated to be strongly associated with aggressive cancer-cell characteristics and poor patient prognosis. In contrast, the frequency of this mutation in pediatric PTC has undergone limited study, and the few available estimates range from 0 to 63%. Furthermore, the role of the BRAF^(V600E) mutation in pediatric PTC is controversial; thus, the present study aimed to investigate the prevalence and role of the BRAF^(V600E) mutation in48 pediatric patients with PTC, aged 3–13 years. Of these patients, 41 were diagnosed with classic PTC, five were found to have a follicular variant of PTC, and two to exhibit a diffuse sclerosing PTC variant. The BRAF^(V600E) mutation was identified to be present in 35.4% of the 48 analyzed patients, and in 41.5% of the patients diagnosed with classical PTC. Furthermore, the presence of the BRAF^(V600E) mutation was found to be associated with a patient age at diagnosis of less than ten years(P=0.011), the performance of a thyroidectomy(P=0.03), exhibited tumor multifocality(P=0.02) and/or extra-thyroidal invasion(P=0.003), and both a low MACIS(Metastases, Age, Completeness of resection, Invasion, Size)(P=0.036) and AMES(Age, Metastasis, Extent of tumor,Size)(P=0.001)score. Together, these data suggest that the presence of the BRAF^(V600E) mutation may be negatively correlated with partial aggressive clinicopathological features of pediatric PTC. | Jiangqiao Geng Huanmin Wang Yuanhu Liu Jun Tai Yaqiong Jin Jie Zhang Lejian He Libing Fu Hong Qin Yingluan Song Jinzhu Su Aiying Zhang Xin Wen Yongli Guo Xin Ni | 2017 | Science China(Life Sciences)2017，60，7： | 9 |
| 4 | Image denoising and deblurring: non-convex regularization, inverse diffusion and shock filter显示文摘A large number of applications in image processing and computer vision depend on image quality. In this paper, main concerns are image denoising and deblurring simultaneously in a restoration task by three types of methodologies: non-convex regularization, inverse diffusion and shock filter. We discuss their relations in the context of image deblurring: the inverse diffusion implied by the non-convex regularization, and the superior ability of deblurring edge of the shock filter to that of the inverse diffusion, both in 1D and 2D cases. Finally, we propose a region-based adaptive anisotropic diffusion with shock filter method, which shows advantages of deblurring edges, denoising and smoothing contours in experiments, compared with some related methods. Therein an idea of 'divide and rule' is introduced. | FU ShuJun 1,2,3 , ZHANG CaiMing 2 & TAI XueCheng 3,4 1 School of Mathematics, Shandong University, Jinan 250100, China 2 School of Computer Science and Technology, Shandong University, Jinan 250101, China 3 School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 639798, Singapore 4 Department of Mathematics, University of Bergen, Bergen 5008, Norway | 2011 | Science China(Information Sciences)2011，54，6： | 8 |
| 5 | Effects of nano-sized Ag reinforcing particulates on the microstructure of Sn-0.7Cu solder joints显示文摘Composite solders were prepared by mechanically dispersing different volumes of nano-sized Ag particles into the Sn-0.7Cu eutectic solder. The effects of Ag particle addition on the microstructure of Sn-0.7Cu solder joints were investigated. Besides, the effects of isothermal aging on the microstructural evolution in the interfacial intermetallic compound (IMC) layer of the Sn-0.7Cu solder and the composite solder reinforced with 1vol% Ag particles were analyzed, respectively. Experimental results indicate that the growth rate of the interfacial IMC layer in the Ag particles reinforced composite solder joint is much lower than that in the Sn-0.7Cu solder joint during isothermal aging. The Ag particles reinforced composite solder joint exhibits much lower layer-growth coefficient for the growth of the IMC layer than the corresponding solder joint. | Feng Tai Fu Guo Zhi-dong Xia Yong-ping Lei Yao-wu Shi | 2009 | International Journal of Minerals,Metallurgy and Materials2009，16，6： | 4 |
| 6 | The effect of polymerization conditions on crystalline of polybutene-1 catalyzed by metallocene catalyst显示文摘Polybutene-1 was synthesized stereoselectively with the precursorη5-(pentamethyl-cyclopentadienyl) tribenzyloxide titanium (Cp*Ti(OBz)3) and methylaluminoxane (MAO). The effects of polymerization conditions, trimethyl alumina (TMA) content in MAO and temperature on the crystalline and molecular weight of the products, and catalytic activity were investigated. The structural properties of the polybutene-1 were characterized with 13C NMR and WAXD. | Qi Gu Huang Ya Ping Sheng Kun Xue Deng Li Fu Ma Yi Xian Wu Wan Tai Yang | 2007 | Chinese Chemical Letters2007，18，2： | 3 |
| 7 | Effects of particle size on the mechanical properties of particle-reinforced Sn-Ag composite solder joint显示文摘Particulate size has significant influenced on the mechanical properties of particle-reinforced composite solder joints. In this current research, Cu or Ni reinforcement particles were mechanically added to the Sn-3.5Ag eutectic solder, and the effects of the particle size on the mechanical properties of particle-reinforced composite solder joint were systematically studied. This investigation touched on how mechanical properties of the solder joints are affected by particles size. A quantitative formula was set up to correlate the mechanical property of the solder joint with particle size in different processing conditions. Besides, the fracture mechanism of the composite solder joint was analyzed. | TAI Feng GUO Fu | 2009 | Science China(Technological Sciences)2009，52，1： | 2 |
| 8 | Aerobic oxidation of benzylic aldehydes to acids catalyzed by iron (Ⅲ) meso-tetraphenylporphyrin chloride under ambient conditions显示文摘Highly efficient aerobic oxidation of benzylic aldehydes to the corresponding acids catalyzed by iron (Ⅲ) meso-tetraphe- nylporphyrin chloride (Fe(TPP)Cl) under ambient conditions was developed.The catalyst has been proved to be an excellent catalyst for the system in the presence of molecular oxygen and isobutryaldehyde at room temperature. | Xian Tai Zhou Hong Bing Ji Qiu Lan Yuan Jian Chang Xu Li Xia Pei Le Fu Wang | 2007 | Chinese Chemical Letters2007，18，8： | 2 |
| 9 | Appropriate choice of collision-induced dissociation energy for qualitative analysis of notoginsenosides based on liquid chromatography hybrid ion trap time-of-flight mass spectrometry显示文摘Liquid chromatography hybrid ion trap/time-of-flight mass spectrometry possesses both the MS^n ability of ion trap and the excellent resolution of a time-of-flight and has been widely used to identify drug metabolites and determine trace multi-components in natural products. Collision energy, one of the most important factors in acquiring MS^n information, could be set freely in the range of 10%–400%. Herein, notoginsenosides were chosen as model compounds to build a novel methodology for the collision energy optimization. Firstly, the fragmental patterns of the representatives for the authentic standards of protopanaxadiol-type and protopanaxatriol-type notoginsenosides were obtained based on accurate MS^2 and MS^3 measurements via liquid chromatography hybrid ion trap/time-of-flight mass spectrometry. The extracted ion chromatograms of characteristic product ions of notoginsenosides in Panax Notoginseng Extract were produced under a series of collision energies and compared to screen the optimum collision energies values for MS^2 and MS^3. The results demonstrated that the qualitative capability of liquid chromatography hybrid ion trap/time-of-flight mass spectrometry was greatly influenced by collision energies, and 50% of MS^2 collision energy was found to produce the highest collision-induced dissociation efficiency for notoginsenosides. Addtionally, the highest collision-induced dissociation efficiency appeared when the collision energy was set at 75% in the MS^3 stage. | WANG Guang-Ji FU Han-Xu XIAO Jing-Cheng YE Wei RAO Tai SHAO Yu-Hao KANG Dian XIE Lin LIANG Yan | 2016 | Chinese Journal of Natural Medicines2016，14，4： | 2 |
| 10 | Handle- aware isolines for scalable shape editing显示文摘 | Au O K C Fu H B Tai C L | 2007 | ACM Transactions on Graphics2007，26，3： | 1 |
| 11 | The microstrueture and phase equilibrium of new high performance high - entropy alloys 显示文摘 | Ker - Chang Hsieh Cheng - Fu Yu Wen - Tai Hsieh Wei - Ren Chiang Jin Son Ku Jiun -Hui Lai Chin -Pan T Chih Chao Yang | 2008 | Journal of Alloys and Compounds2008，，8： | 1 |
| 12 | Computational aero- acoustic analysis of a passenger car with a rear spoiler显示文摘 | Tsai C H Fu L M Tai C H | 2009 | Applied Mathematical Modelling2009，33，9： | 1 |
| 13 | LEAFY COTYLEDON1 Is a Key Regulator of Fatty Acid Biosynthesis in Arabidopsis1[W][OA]显示文摘 | Mu Jinye Tan Helin Zheng Qi Fu Fuyou Liang Yan Zhang Jian Yang Xiaohui Wang Tai Chong Kang Wang Xiu-Jie Zuo Jianru | 2008 | Plant Physiology2008，，2： | 1 |
| 14 | On Crossover Adjustment in Satellite Altimetry and Its Oceanographic Implications显示文摘 | TAI C K FU L L | 1986 | Journal of Geophysical Research1986，91，2： | 1 |
| 15 | Cancer therpy using a self-replicating RNA vaccine显示文摘 | Ying H Tai Z Zarks Rong Fu Wang | 1999 | Nature Medine1999，5，7： | 1 |
| 16 | Molecularly Imprinted Polymers on Chloromethyl Polystyrene Resin Prepared via RAFT Polymerization显示文摘Surface molecularly imprinted polymers (SMIP) was prepared via the reversible addition-fragmentation chain transfer (RAFT) polymerization on the chloromethyl polystyrene resin (CPR) in the presence of the template D-phenylalanine. The structure of SMIP was characterized by FTIR and SEM. The adsorption behavior of D-phenylalanine of SMIP was preliminarily investigated. | Zhen Xia DU Hong LIU Zhi Feng FU Wan Tai YANG | 2006 | Chinese Chemical Letters2006，17，4： | 1 |
| 17 | Handle-aware isolines for scalable shape editing 显示文摘 | Au O K C Fu H Tai C L | 2007 | ACM Transactions on Graphics2007，26，3： | 1 |
| 18 | How Chillers React to Building Loads显示文摘 | Work Tai Chan Fu Wing Yu | 2004 | ASHRAE Journal2004，，： | 1 |
| 19 | Process parameter optimization for MIMO plastic injection molding via soft computing显示文摘 | CHEN W C FU G L TAI P H DENG W J | 2009 | Expert Systems with Applications2009，36，2： | 1 |
| 20 | Factors associated with career deci- sion in Tai wan nursing students: a questionnaire survey显示文摘 | Hui LL Tai C Fu MC | 2006 | Int J Nursing Studies2006，43，5： | 1 |
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