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| 1 | Variations of mitochondrial D-loop region plus downstream gene 1 2S rRNA-tRNA^(phe) and gastric carcinomas显示文摘AIM: To explore the instabilities, polymorphisms and other variations of mitochondrial D-loop region and downstream gene 12S rRNA-tRNAPhe in gastric cancers, and to study their relationship with gastric cancer.METHODS: Three adjacent regions (D-loop, tRNAphe and 12S rRNA) were detected for instabilities, polymorphisms and other variations via PCR amplification followed by direct DNA sequencing in 22 matched gastric cancerous tissues and para-cancerous normal tissues.RESULTS: PolyC or (CA)n instabilities were detected in 13/22(59.1%) gastric cancers and 9/22(40.9 %) in the control (P>0.05). There existed 2/12(16.7%) and 6/10(60%)alterations of 12S rR NA-tRNAphe in well differentiated gastric cancers and poorly differentiated ones, respectively(P0.05).Some new variations were found, among which np 318 and np 321 C-T transitions in D-loop region were two of the five bases for H-strand replication primer. Np 523 AC-deletion and np 527 C-T transition occurred at mtTF1 binding site (mtTFBS), which were associated with the transcription of downstream mitochondrial genome. Seven samples showed the np 16 182 polyC instabilities, five of which simultaneously showed np 16 189 T-C transitions.CONCLUSION: There is no statistic significance of instabilities and polymorphisms in mitochondrial D-loop region between gastric cancerous and para-cancerous normal tissues, which suggests that the instability might relate to heredity or be dependent on aging. There is asignificant correlation between differentiation degree of gastric cancer and variant frequencies of 12S rRNA-tRNAphe. The poorly differentiated gastric cancers are more prone to 12S rRNAtRNAphe variations, or gastric cancers with 12S rRNA-tRNAphe variations are more likely to be poorly differentiated, np 16189 T-C transition may be one of the important reasons for polyC instability in gastric cancer. | Cheng-BoHan FanLi Yu-JieZhao Jia-MingMa Dong-YingWu Yu-KuiZhang YanXin | 2003 | World Journal of Gastroenterology2003，9，9： | 20 |
| 2 | Cloud model-based analysis of regional sustainable water resource utilization schemes显示文摘Given the adverse effects of current water shortages,low utilization and imbalance between the supply and demand,and other status quo problems relating to social economic development,the construction industry and agriculture,a cloud model was applied to a water resource system using five sustainable water resource utilization schemes for Kiamusze,Heilongjiang Province,as an example.This research changes the qualitative description of the concept language into a quantitative analysis of an evaluation indicator.A cloud model-based analytical method for regional sustainable water resource utilization schemes was proposed,and the sustainable grades of the water resources were calculated.The research results showed that,in addition to the natural continuation of such schemes,the development trends of four new schemes achieved the sustainable utilization of water resources,and thus,the sustainable water resource utilization was optimized.However,when the open-source,throttle,comprehensive and coordination schemes were subjected to the optimum applicability analysis,based on the limiting factors in different periods,resource availability and long-term development,decision-making regarding the best solution in different periods better ensures sustainable development in Kiamusze.The research results provide a significant theoretical basis for the formulation of scientific and reasonable sustainable water resource utilization strategies in Kiamusze. | Fu Qiang Meng Fanxiang Li Tianxiao Liu Dong Gong Fanli Amgad Osman Li Yutong | 2016 | International Journal of Agricultural and Biological Engineering2016，9，5： | 4 |
| 3 | The Syntax, Semantics and Pragmatics of 'lian…dou'显示文摘This article treats the chunk‘lian…dou’an a complex conjunction on the ground that the sentence that follows the sentence in which the chunk ‘lian…dou’occurs is often incomplete.The interpretation of the incomplete sentence,or the sentence fragment,calls for the restoration of the elided constituents by reconstruction.Moreover,the proposition expressed by the sentence fragment is entailed by the proposition expressed by the sentence in which the chunk‘lian…dou’occurs.Following Montague’s rule-to-rule hypothesis,we can take the entailment inherent in the whole construction as the syntactic reflex in its semantics.Since the entailment is obviously induced by the chunk‘lian…dou’,we treat it as a complex conjunction.Section 1 demonstrates that the sentence that follows the sentence in which the chunk‘lian…dou’occurs is not independent and in many ways is similar to the ‘ruguo…(name)’construction.Section 2 develops a scalar model based on Fillmore et al (1988)for the semantic interpretation of the construction,and gives an account of a variety of ‘lian…dou’sentences.Section 3 addresses the pragmatic aspect of the construction.It also argues that the first proposition conjoined by ‘lian…dou’itself has the function of simultaneously meeting the Gricean Maxims of Relevance,Quality and Quantity,thus making the verbalization of the second proposition unnecessary. | 方立 FanLi | 2002 | 暨南大学华文学院学报2002，，4： | 2 |
| 4 | Research and development of a novel subunit vaccine for the currently circulating pseudorabies virus variant in China显示文摘Pseudorabies(PR)is a devastating viral disease which leads to fatal encephalitis and respiratory disorders in pigs.Commercial gE-deleted live pseudorabies virus(PRV)vaccine has been widely used to control this disease in China.However,the new-emerging variants of PRV compromises the protection provided by current vaccines and lead to the outbreak of PR in vaccinated pig herds.Several killed and live vaccine candidates based on current PRV variants have been reported to be effective to control the disease.A subunit vaccine based on gB protein,one major PRV glycoprotein which elicits strong humoral and cellular immune responses,however,was never evaluated for protection against the current circulating PRV variants.In this study,full-length PRV gB protein was successfully expressed in baculovirus/insect cells in the soluble format and was tested on 3-week-old piglets as a subunit vaccine.Compared with unvaccinated pigs,the gB-vaccinated pigs developed specific antibody-mediated responses and were protected from the virulent PRV HN1201 challenge.All vaccinated pigs survived without showing any PRV-specific respiratory and neurological signs,but all unvaccinated pigs died within 7 days after HN1201 challenge.Hence,this novel gB-based vaccine could be applied as an effective subunit vaccine to control PRV variant in China. | Yuzhou WANG Tongyan WANG He YAN Fanli YANG Linghua GUO Qingyuan YANG Xule HU Feifei TAN Yan XIAO Xiangdong LI Kegong TIAN | 2015 | Frontiers of Agricultural Science and Engineering2015，2，3： | 2 |
| 5 | Interleukin-17 Signaling in Inflammatory, Kupffer Cells, and Hepatic Stellate Cells Exacerbates Liver Fibrosis in Mice显示文摘 | Fanli Meng Kai Wang Tomonori Aoyama Sergei I. Grivennikov YongHan Paik David Scholten Min Cong Keiko Iwaisako Xiao Liu Mingjun Zhang Christoph H. ?sterreicher Felix Stickel Klaus Ley David A. Brenner Tatiana Kisseleva | 2012 | Gastroenterology2012，，3： | 1 |
| 6 | Near infrared electrochromism of lutetium phthalocyanine显示文摘 | Zhang Jidong Lu Fanli Huang Haichao | 2005 | Synthetic Met-als2005，148，： | 1 |
| 7 | A three-dimensional hierarchical CdO nanostructure: Preparation and its improved gas-diffusing performance in gas sensor显示文摘 | Xiangqian Fu Jinyun Liu Tianli Han Xiaoman Zhang Fanli Meng Jinhuai Liu | 2013 | Sensors & Actuators: B Chemical2013，，： | 1 |
| 8 | The application of macroporous adsorption resin in the purification of the traditional Chinese medicine compound显示文摘 | CongMM(从毛勉) ShengFB(盛方标) FanLY(范鲁雁) | 2009 | 安徽医药2009，13，： | 1 |
| 9 | Metal oxide nanostructures and their gas sensing properties: A review 显示文摘 | Sun Yufeng Liu Shaobo Meng Fanli | 2012 | Sensors2012，12，3： | 1 |
| 10 | Gas Sensing Behavior of a Single Tin Dioxide Sensor under Dynamic Temperature Modulation显示文摘 | Huang Xingjiu Meng Fanli Pi Zongxin et al | 2004 | Sensors and Actuators B2004，99，23： | 1 |
| 11 | Interleukin-17 Signaling in Inflammatory, Kupffer Cells, and Hepatic Stellate Cells Exacerbates Liver Fibrosis in Mice显示文摘 | Fanli Meng Kai Wang Tomonori Aoyama Sergei I. Grivennikov YongHan Paik David Scholten Min Cong Keiko Iwaisako Xiao Liu Mingjun Zhang Christoph H. ?sterreicher Felix Stickel Klaus Ley David A. Brenner Tatiana Kisseleva | 2012 | Gastroenterology2012，，3： | 1 |
| 12 | Novel capacitive sensor: Fabrication from carbon nanotube arrays and sensing property characterization显示文摘 | Yan Chen Fanli Meng Minqiang Li Jinhuai Liu | 2009 | Sensors & Actuators: B Chemical2009，，2： | 1 |
| 13 | Stndy of Influencing Factors of Dynamic Measurenaents Based on SnO2 Gas Sensor显示文摘 | Yufeng Stm Xingjiu Hnang Fanli Meng Jinhuai Liu | 2004 | Seusors2004，4，： | 1 |
| 14 | Catalyst-free growth of one-dimensional ZnO nanostructures on SiO 2 substrate and in situ investigation of their H 2 sensing properties显示文摘 | Xiaoguang San Guosheng Wang Bing Liang Yinmin Song Shangyao Gao Jinsong Zhang Fanli Meng | 2015 | Journal of Alloys and Compounds2015，，： | 1 |
| 15 | Interlaced nanoflake-assembled flower-like hierarchical ZnO microspheres prepared by bisolvents and their sensing properties to ethanol显示文摘 | Fanli Meng Sheng Ge Yong Jia Bai Sun Yufeng Sun Chen Wang Hao Wu Zhen Jin Minqiang Li | 2015 | Journal of Alloys and Compounds2015，，： | 1 |
| 16 | Study on resonance frequency of thermoacoustic resonance pipes显示文摘For calculating the resonance frequency of practical resonance pipes more precisely, two methods are presented, which are the method of acoustic pressure simulation and the method of minimum point of standing wave. Both methods are based on the theoretical simulation of the acoustic pressure distribution in the pipe and the relation between the minimum point position of the standing wave and the acoustic impedances of the pipe terminations. It is demonstrated that both methods can calculate the resonance frequency of a pipe more precisely by considering the effect of the acoustic resistances of both terminations of the pipe. Therefore both methods presented are more useful in acoustic research fields in which the resonance frequency of a pipe must be controlled strictly. In addition, both methods can get the same calculation results despite of their different ways. The method of the minimum point of standing wave is more convenient, nevertheless the method of acoustic pressure simulation can derive the resonance frequency and the distribution of the acoustic pressure in the pipe simultaneously. | FANLi WANGBenren JINTao ZHANGShuyi | 2005 | Chinese Journal of Acoustics2005，24，1： | 1 |
| 17 | Crystal structure of SARS-CoV-2 nsp10/nsp162′-O-methylase and its implication on antiviral drug design显示文摘Dear Editor,The unexpected outbreak of a novel human coronavirus infection has imposed great threat to public health.Thus far,this newly-identified virus has spread to 215 countries and territories,infected more than 3.5 million people,and caused over 240,000 deaths worldwide.1 Although intensified countermeasures have been implemented globally to control the virus infection,the pandemic is still surging with a daily increase in infection case of over 65,000 ever since April 1st 2020.1 No prophylactic vaccines or clinical drugs are currently available to prevent or treat the disease,namely coronavirus disease 2019(COVID-19). | Sheng Lin Hua Chen Fei Ye Zimin Chen Fanli Yang Yue Zheng Yu Cao Jingxin Qiao Shengyong Yang Guangwen Lu | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 1 |
| 18 | Flower-like hierarchical structures consisting of porous single-crystalline ZnO nanosheets and their gas sensing properties to volatile organic compounds (VOCs)显示文摘 | Fanli Meng Nannan Hou Sheng Ge Bai Sun Zhen Jin Wei Shen Lingtao Kong Zheng Guo Yufeng Sun Hao Wu Chen Wang Minqiang Li | 2014 | Journal of Alloys and Compounds2014，，： | 1 |
| 19 | Gas sensing behavior of a single tin dioxide sensor under dynamic temperature modulation显示文摘 | Huang Xingjiu Meng Fanli Pi Zongxin | 2004 | Sensors and Actuators B2004，99，23： | 1 |
| 20 | Synthesis and gas sensing properties of hierarchical meso-macroporous SnO 2 for detection of indoor air pollutants显示文摘 | Huihua Li Fanli Meng Jinyun Liu Yufeng Sun Zhen Jin Lingtao Kong Yanjiao Hu Jinhuai Liu | 2012 | Sensors & Actuators: B. Chemical2012，，： | 1 |
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