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| 1 | Intestinal dendritic cells in the pathogenesis of inflammatory bowel disease显示文摘The gastrointestinal tract harbors a large number and diverse array of commensal bacteria and is an important entry site for pathogens.For these reasons,the intestinal immune system is uniquely dedicated to protect against infections,while avoiding the development of destructive inflammatory responses to the microbiota.Several models have been proposed to explain how the immune system discriminates between,and appropriately responds to,commensal and pathogenic microorganisms.Dendritic cells(DCs)and regulatory T cells(Treg)are instrumental in maintaining immune homeostasis and tolerance in the gut.DCs are virtually omnipresent and are remarkably plastic,having the ability to adapt to the influences of the microenvironment.Different DC populations with partially overlapping phenotypic and functional properties have been described in different anatomical locations.DCs in the draining mesenteric lymph nodes,in the intestinal lamina propria and in Peyer's patches partake both in the control of intestinal inflammation and in the maintenance of gut tolerance.In this respect,gutresident DCs and macrophages exert tolerogenic functions as they regularly encounter and sense commensal bacteria.In contrast,migrating DC subsets that are recruited to the gut as a result of pathogenic insults initiate immune responses.Importantly,tolerogenic DCs act by promoting the differentiation and expansion of Treg cells that efficiently modulate gut inflammation,as shown both in preclinical models of colitis and in patients with inflammatory bowel disease(IBD).This article reviews the phenotypic and functional features of gut DC subsets and discusses the current evidence underpinning the DC contribution to the pathogenesis of the major clinical subtypes of human IBD.It also addresses the potential clinical benefit derived from DC targeting either in vivo or in vitro. | Sergio Rutella Franco Locatelli | 2011 | World Journal of Gastroenterology2011，17，33： | 13 |
| 2 | Mesenchymal Stem/Stromal Cells: A New ’’Cells as Drugs’’ Paradigm. Efficacy and Critical Aspects in Cell Therapy显示文摘 | Laura de Girolamo Enrico Lucarelli Giulio Alessandri Maria Antonietta Avanzini Maria Ester Bernardo Ettore Biagi Anna Teresa Brini Giovanna D’Amico Franca Fagioli Ivana Ferrero Franco Locatelli Rita Maccario Mario Marazzi Ornella Parolini Augusto Pessina | 2013 | Current Pharmaceutical Design2013，，： | 1 |
| 3 | Lung Ultrasound-Implemented Diagnosis of Acute Decompensated Heart Failure in the ED显示文摘 | Emanuele Pivetta Alberto Goffi Enrico Lupia Maria Tizzani Giulio Porrino Enrico Ferreri Giovanni Volpicelli Paolo Balzaretti Alessandra Banderali Antonello Iacobucci Stefania Locatelli Giovanna Casoli Michael B. Stone Milena M. Maule Ileana Baldi Franco M | 2015 | Chest2015，，： | 1 |
| 4 | Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study显示文摘 | Katarina Le Blanc Francesco Frassoni Lynne Ball Franco Locatelli Helene Roelofs Ian Lewis Edoardo Lanino Berit Sundberg Maria Ester Bernardo Mats Remberger Giorgio Dini R Maarten Egeler Andrea Bacigalupo Willem Fibbe Olle Ringdén | 2008 | The Lancet . 2008 (9624)2008，，： | 1 |
| 5 | Light chain deposition disease with renal involvement: clinical characteristics and prognostic factors显示文摘 | Claudio Pozzi Marco D’Amico Giovanni B Fogazzi Simona Curioni Franco Ferrario Sonia Pasquali Giacomo Quattrocchio Cristiana Rollino Siro Segagni Francesco Locatelli | 2003 | American Journal of Kidney Diseases2003，，6： | 1 |
| 6 | Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study显示文摘 | Katarina Le Blanc Francesco Frassoni Lynne Ball Franco Locatelli Helene Roelofs Ian Lewis Edoardo Lanino Berit Sundberg Maria Ester Bernardo Mats Remberger Giorgio Dini R Maarten Egeler Andrea Bacigalupo Willem Fibbe Olle Ringdén | 2008 | The Lancet2008，，9624： | 1 |
| 7 | T reg cells: Collection, processing, storage and clinical use显示文摘 | Nicola Daniele Maria Cristina Scerpa Fabiola Landi Maurizio Caniglia Massimino Jan Miele Franco Locatelli Giancarlo Isacchi Francesco Zinno | 2011 | Pathology - Research and Practice2011，，4： | 1 |
| 8 | Risk Factors and Severe Outcome in Thrombotic Microangiopathy After Allogeneic Hematopoietic Stem Cell Transplantation显示文摘 | Cornelio Uderzo Sonia Bonanomi Alessandro Busca Mila Renoldi Pierantonio Ferrari Massimo Iacobelli Giuseppe Morreale Edoardo Lanino Claudio Annaloro Aldo Della Volpe Paolo Alessandrino Daniela Longoni Franco Locatelli Haidi Sangalli Attilio Rovelli | 2006 | Transplantation2006，，： | 1 |
| 9 | The ectopic expression of the rice Osmyb4 gene in Arabidopsis increases tolerance to abiotic, environmental and biotic stresses显示文摘 | Candida Vannini Marcello Iriti Marcella Bracale Franca Locatelli Franco Faoro Paolo Croce Raul Pirona Antimo Di Maro Immacolata Coraggio Annamaria Genga | 2007 | Physiological and Molecular Plant Pathology2007，，1： | 1 |
| 10 | Analysis of risk factors influencing outcomes after cord blood transplantation in children with juvenile myelomonocytic leukemia: a EUROCORD, EBMT, EWOG-MDS, CIBMTR study显示文摘 | Franco Locatelli Alessandro Crotta Annalisa Ruggeri Mary Eapen John E. Wagner Margaret L. MacMillan Marco Zecca Joanne Kurtzberg Carmem Bonfim Ajay Vora Cristina Díaz de Heredia Lochie Teague Jerry Stein Tracey A. O’Brien Henrique Bittencourt Adrienne Mad | 2013 | Blood2013，，12： | 1 |
| 11 | Allogeneic Hematopoietic Stem Cell Transplantation May Restore Gluten Tolerance in Patients With Celiac Disease显示文摘 | Rachele Ciccocioppo Maria Ester Bernardo Maria Luisa Russo Alessandro Vanoli Carla Franco Myriam Martinetti Laura Catenacci Giovanna Giorgiani Marco Zecca Antonio Piralla Fausto Baldanti Franco Locatelli Gino Roberto Corazza | 2013 | Journal of Pediatric Gastroenterology and Nutrition2013，，4： | 1 |
| 12 | Reduced-Intensity Regimens in Allogeneic Hematopoietic Stem Cell Transplantation for Hemoglobinopathies显示文摘 | Franco Locatelli | 2006 | Hematology2006，，： | 1 |
| 13 | Health Staff Ready to Work without Borders显示文摘 | Franco Locatelli Sabina Tangerini Mattia Viano Chiara Schiavo Lisa Di Mascolo Alessia Montanari Laura Palmucci Marilena Bertini | 2018 | Journal of Health Science2018，6，5： | 0 |
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