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| 1 | Paradoxical reduction of cerebral blood flow after acetazolamide loading:a hemodynamic and metabolic study with ^(15)O PET显示文摘Paradoxical reduction of cerebral blood flow(CBF)after administration of the vasodilator acetazolamide is the most severe stage of cerebrovascular reactivity failure and is often associated with an increased oxygen extraction fraction(OEF).In this study,we aimed to reveal the mechanism underlying this phenomenon by focusing on the ratio of CBF to cerebral blood volume(CBV)as a marker of regional cerebral perfusion pressure(CPP).In 37patients with unilateral internal carotid or middle cerebral arterial(MCA)steno-occlusive disease and8 normal controls,the baseline CBF(CBF_b),CBV,OEF,cerebral oxygen metabolic rate(CMRO_2),and CBF after acetazolamide loading in the anterior and posterior MCA territories were measured by^(15)O positron emission tomography.Paradoxical CBF_b reduction was found in 28 of 74 regions(18of 37 patients)in the ipsilateral hemisphere.High CBF_b(>47.6 mL/100 mL/min,n=7)was associated with normal CBF_b/CBV,increased CBV,decreased OEF,and normal CMRO_2.Low CBF_b(<31.8 mL/100mL/min,n=9)was associated with decreased CBF_b/CBV,increased CBV,increased OEF,and decreased CMRO_2.These findings demonstrated that paradoxical CBF reduction is not always associated with reduction of CPP,but partly includes highCBF_b regions with normal CPP,which has not been described in previous studies. | Tadashi Watabe Eku Shimosegawa Hiroki Kato Kayako Isohashi Mana Ishibashi Mitsuaki Tatsumi Kazuo Kitagawa Toshiyuki Fujinaka Toshiki Yoshimine Jun Hatazawa | 2014 | Neuroscience Bulletin2014，30，5： | 3 |
| 2 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017，25，5： | 2 |
| 3 | Expression of MMP-9 in mesangial cells and its changes in anti-GBM glomerulonephritis in WKY rats显示文摘 | Kuroda T Yoshida Y Kamiie J Kovalenko P Nameta M Fujinaka H Yaoita E Endo T Ishizuka S Nakabayashi K Yamada A Nagasawa T Yamamoto T | 2004 | Clin Exp Nephrol2004，8，： | 1 |
| 4 | Genetic mapping of the QTL affecting body weight in chickens using a F2 family 显示文摘 | Tatsuda T Fujinaka K | 2001 | British Poultry Science2001，42，： | 1 |
| 5 | Effectiveness of local cooling and lidocaine administration for prevention of pain upon injection of propofol显示文摘 | Terada N Takubo I Fujinaka W | 2014 | Masui2014，63，8： | 1 |
| 6 | Effectiveness of local cooling and lidocaine administration for prevention of pain upon injection of propofol显示文摘 | Terada N Takubo I Fujinaka W | 2014 | Masui2014，63，8： | 1 |
| 7 | Cuprous oxide-indium-tin oxide thin film photovoltaic cells显示文摘 | BEREZIN A A | 1983 | J Appl Phys1983，54，： | 1 |
| 8 | Bill Classification by Using the LVQ Method显示文摘 | TOSHIHISA Kosaka SIGERU Omatu TORU Fujinaka | 2001 | International Joint Conference on Neural Networks2001，5，： | 1 |
| 9 | Joining of Bi-2223 sintered bulk using superconductors paste显示文摘 | Haseyama S Fujinaka N Yoshizama S | 2001 | Physica C2001，356，： | 1 |
| 10 | Genetic mapping of a body weight trait in chicken显示文摘 | TATSUDA K FUJINAKA K YAMASAKI T | 2000 | Animal Science Journal2000，71，2： | 1 |
| 11 | Genetic mapping of the QTL affecting body weight in chickens using a F2 family显示文摘 | TATSUDA K FUJINAKA K | 2001 | British Poultry Science2001，42，3： | 1 |
| 12 | Expression and localization of insulin-like growth factor binding proteins in normal and proteinuric kidney glomeruli显示文摘 | Fujinaka H Katsuyama K Yamamoto K | 2010 | Nephrology2010，15，7： | 1 |
| 13 | Suppression of anti-glomeruar basement membrane nephritis by administration of anti-monocyte chemoattractant protein-1 antibody in WKY rats显示文摘 | Fujinaka H Yamamoto T Takeya M | 1997 | J Am Soc Nephrol1997，8，7： | 1 |
| 14 | A case of caesarean section in a patient with myasthenia gravis:crisis was successfully avoided by preoperative plasmapheresis 显示文摘 | Kuroda K Fujinaka W Takatori M | 2009 | Masui2009，58，11： | 1 |
| 15 | Protein kinase C-zeta activation markedly enhances β-cell proliferation: an essential role in growth factor mediated β-cell mitogenesis显示文摘 | Vasavada RC Wang L Fujinaka Y | 2007 | Diabetes2007，56，： | 1 |
| 16 | Genetic mapping of the QTL affecting body weight in chickens using a F2 family显示文摘 | Fujinaka K | 2001 | British Poultry Sci2001，42，： | 1 |
| 17 | Protein kinase C-zeta activation markedly enhances beta-cell proliferation:an essential role in growth factor mediated beta-cell mitogenesis显示文摘 | VASAVADA R C WANG L FUJINAKA Y | 2007 | Diabetes2007，56，11： | 1 |
| 18 | Expression ofthe chem- okine fractalkine ( FKN/CX3CL1 ) by podocytes in normal and proteinuric rat kidney glomerulus 显示文摘 | Katsuyama K Fujinaka H Yamamoto K | 2009 | Nephron Expe Nephrol2009，113，2： | 1 |
| 19 | Expression of MMP-9 in mesangial cells and its changes in anti-GBM glomerulonephritis in WKY rats显示文摘 | Tadahide Kuroda Yutaka Yoshida Junichi Kamiie Pavel Kovalenko Masaaki Nameta Hidehiko Fujinaka Eishin Yaoita Tetsuya Endo Shunji Ishizuka Kimimasa Nakabayashi Akira Yamada Toshihiko Nagasawa Tadashi Yamamoto | 2004 | Journal of Clinical and Experimental Nephrology2004，，3： | 1 |
| 20 | FANCJ expression pre- dicts the response to 5-Fluorouracil-Based Chemotherapy in MLH1 - proficient colorectal cancer显示文摘 | Nakanishi R Kitao H Fujinaka Y | 2012 | Ann Surg Oncol2012，19，11： | 1 |
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