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| 1 | Protolith ages and timing of peak and retrograde metamorphism of the high-pressure granulites in the Shandong Peninsula,eastern North China Craton显示文摘高压(HP ) granulites 广泛地在 tonalite-trondhjemite-granodiorite (TTG ) 以内作为被外国领地包围的土地发生在山东半岛的早前寒武纪的变形地下室的片麻岩,北方中国 Craton (NCC ) 的东南部分。基于阴极射线发光(CL ) ,激光拉曼光谱学并且在原处标明日期的 U-Pb,我们从 HP granulites 描绘锆石并且组织他们进三种主要类型:继承(magmatic ) 锆石, HP 变形锆石并且后退锆石。有清楚或弱定义的 magmatic zoning 的继承锆石包含 29152890 妈和 27632510 妈的磷灰石,和 207Pb/206Pb 年龄的包括,与在太古代地下室的二个 magmatic 事件相关。同类的 HP 变形锆石包括石榴石, clinopyroxene,斜长石,石英,金红石和磷灰石包含高压的变态的索引矿物质,并且产出在 1900 和 1850 妈之间的 207Pb/206Pb 年龄,标记预定山峰 HP granulite 外形变态。retrograde 锆石包含 orthopyroxene,斜长石,石英,磷灰石和闪石的包括,并且在三个组之中产出 18401820 妈的最年轻的 207Pb/206Pb 年龄,我们它相关到媒介到低压的 granulite 外形后退变态。数据在这研究介绍了建议中央的 subduction -- 并且降低他们在 Palaeoproterozoic (19001850 妈) 期间受到 HP granulite 外形变态的外壳深度的 Neoarchean magmatic protoliths。随后, HP granulites 是到上面的外壳层次的 exhumated,并且被媒介套印到低压的 granulite 和角闪岩外形后退在 ca 的事件。1840820 妈。 | Pinghua Liu Fulai Liu Hong Yang Fang Wang Jianhui Liu | 2012 | Geoscience Frontiers2012，3，6： | 19 |
| 2 | Microstructure, biodegradation, antibacterial and mechanical properties of ZK60-Cu alloys prepared by selective laser melting technique显示文摘Magnesium(Mg) alloys are receiving increasing attention for body implants owing to their good biocompatibility and biodegradability. However, they often suffer from bacterial infections on account of their insufficient antibacterial ability. In this study, ZK60-x Cu(x = 0, 0.2, 0.4, 0.6 and 0.8 wt%) alloys were prepared by selective laser melting(SLM) with alloying copper(Cu) to enhance their antibacterial ability.Results showed that ZK60-Cu alloys exhibited strong antibacterial ability due to combination of release of Cu ions and alkaline environment which could kill bacteria by destroying cellular membrane structure,denaturing enzymes and inhibiting deoxyribonucleic acid(DNA) replication. In addition, their compressive strength increased due to grain refinement and uniformly dispersing of short-bar shaped MgZnCu phases. Moreover, ZK60-Cu alloys also exhibited good cytocompatibility. In summary, ZK60-Cu alloys with antibacterial ability may be promising implants for biomedical applications. | Cijun Shuai Long Liu Mingchun Zhao Pei Feng Youwen Yang Wang Guo Chengde Gao Fulai Yuan | 2018 | Journal of Materials Science & Technology2018，34，10： | 12 |
| 3 | A kernel learning framework for domain adaptation learning显示文摘Domain adaptation learning(DAL) methods have shown promising results by utilizing labeled samples from the source(or auxiliary) domain(s) to learn a robust classifier for the target domain which has a few or even no labeled samples.However,there exist several key issues which need to be addressed in the state-of-theart DAL methods such as sufficient and effective distribution discrepancy metric learning,effective kernel space learning,and multiple source domains transfer learning,etc.Aiming at the mentioned-above issues,in this paper,we propose a unified kernel learning framework for domain adaptation learning and its effective extension based on multiple kernel learning(MKL) schema,regularized by the proposed new minimum distribution distance metric criterion which minimizes both the distribution mean discrepancy and the distribution scatter discrepancy between source and target domains,into which many existing kernel methods(like support vector machine(SVM),v-SVM,and least-square SVM) can be readily incorporated.Our framework,referred to as kernel learning for domain adaptation learning(KLDAL),simultaneously learns an optimal kernel space and a robust classifier by minimizing both the structural risk functional and the distribution discrepancy between different domains.Moreover,we extend the framework KLDAL to multiple kernel learning framework referred to as MKLDAL.Under the KLDAL or MKLDAL framework,we also propose three effective formulations called KLDAL-SVM or MKLDAL-SVM with respect to SVM and its variant μ-KLDALSVM or μ-MKLDALSVM with respect to v-SVM,and KLDAL-LSSVM or MKLDAL-LSSVM with respect to the least-square SVM,respectively.Comprehensive experiments on real-world data sets verify the outperformed or comparable effectiveness of the proposed frameworks. | TAO JianWen CHUNG FuLai WANG ShiTong | 2012 | Science China(Information Sciences)2012，55，9： | 10 |
| 4 | Development and utilization of a new chemically-induced soybean library with a high mutation density显示文摘Mutagenized populations have provided important materials for introducing variation and identifying gene function in plants. In this study, an ethyl methanesulfonate(EMS)-induced soybean(Glycine max) population,consisting of 21,600 independent M_2 lines, was developed.Over 1,000 M_(4(5))families, with diverse abnormal phenotypes for seed composition, seed shape, plant morphology and maturity that are stably expressed across different environments and generations were identified. Phenotypic analysis of the population led to the identification of a yellow pigmentation mutant, gyl, that displayed significantly decreased chlorophyll(Chl) content and abnormal chloroplast development. Sequence analysis showed that gyl is allelic to Minn Gold, where a different single nucleotide polymorphism variation in the Mg-chelatase subunit gene(ChlI1a) results in golden yellow leaves. A cleaved amplified polymorphic sequence marker was developed and may be applied to marker-assisted selection for the golden yellow phenotype in soybean breeding. We show that the newly developed soybean EMS mutant population has potential for functional genomics research and genetic improvement in soybean. | Zhongfeng Li Lingxue Jiang Yansong Ma Zhongyan Wei Huilong Hong Zhangxiong Liu Jinhui Lei Ying Liu Rongxia Guan Yong Guo Longguo Jin Lijuan Zhang Yinghui Li Yulong Ren Wei He Ming Liu Nang Myint Phyu Sin Htwe Lin Liu Bingfu Guo Jian Song Bing Tan Guifeng Liu Maiquan Li Xianli Zhang Bo Liu Xuehui Shi Sining Han Sunan Hua Fulai Zhou Lili Yu Yanfei Li Shuang Wang Jun Wang Ruzhen Chang Lijuan Qiu | 2017 | Journal of Integrative Plant Biology2017，59，1： | 6 |
| 5 | A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor显示文摘Glucagon-like peptides(GLP-1 and GLP-2)are two proglucagon-derived intestinal hormones that mediate distinct physiological functions through two related receptors(GLP-1R and GLP-2R)which are important drug targets for metabolic disorders and Crohn's disease,respectively.Despite great progress in GLP-1 R structure determination,our understanding on the differences of peptide binding and signal transduction between these two receptors remains elusive.Here we report the electron microscopy structure of the human GLP-2R in complex with GLP-2 and a Gs heterotrimer.To accommodate GLP-2 rather than GLP-1,GLP-2R fine-tunes the conformations of the extracellular parts of transmembrane helices(TMs)1,5,7 and extracellular loop 1(ECL1).In contrast to GLP-1,the N-terminal histidine of GLP-2 penetrates into the receptor core with a unique orientation.The middle region of GLP-2 engages with TM1 and TM7 more extensively than with ECL2,and the GLP-2 C-terminus closely attaches to ECL1,which is the most protruded among 9 class B G protein-coupled receptors(GPCRs).Functional studies revealed that the above three segments of GLP-2 are essential for GLP-2 recognition and receptor activation,especially the middle region.These results provide new insights into the molecular basis of ligand specificity in class B GPCRs and may facilitate the development of more specific therapeutics. | Wen Sun Li-Nan Chen Qingtong Zhou Li-Hua Zhao Dehua Yang Huibing Zhang Zhaotong Cong Dan-Dan Shen Fenghui Zhao Fulai Zhou Xiaoqing Cai Yan Chen Yan Zhou Sarina Gadgaard Wijnand JCvan der Velden Suwen Zhao Yi Jiang Mette MRosenkilde HEric Xu Yan Zhang Ming-Wei Wang | 2020 | Cell Research2020，30，12： | 4 |
| 6 | The evolution of microstructure and texture of AZ80 Mg alloy cup-shaped pieces processed by rotating backward extrusion显示文摘This study proposed an effective plastic deformation technique,rotating backward extrusion(RBE),for producing high performance AZ80 magnesium alloy cup-shaped pieces.The RBE process was carried on the Gleeble-3500 test machine at 653 K,and the conventional backward extrusion(CBE)was also conducted for comparison.A detailed microstructure analysis was performed using the optical microscopy(OM)and electron back-scatter diffraction(EBSD).The results shown that the equivalent strain and deformation uniformity of the cup pieces could be substantially increased by the RBE process compared with the CBE process.Furthermore,the RBE process could significantly improve the grain refining capacity and the proportion of dynamic recrystallization(DRX),of which the maximum reduction of grain size was 88.60%,and the maximum increase of DRX proportion was 55.30%in the cup bottom.The main deformation mechanism of the RBE process was the discontinuous DRX(DDRX),while the continuous DRX(CDRX)was also occurred in the cup transition.Compared with the CBE sample,the texture of the cup bottom was weakened for the RBE sample.The microhardness value of the RBE sample was higher than that of the CBE sample,which can be attributed to the grain refinement strengthening. | Xin Che Qiang Wang Beibei Dong Mu Meng Zhi Gao Kai Liu Jin Ma Fulai Yang Zhiming Zhang | 2021 | Journal of Magnesium and Alloys2021，9，5： | 4 |
| 7 | Depositional Age, Provenance Characteristics and Tectonic Setting of the Ailaoshan Group in the Southwestern South China Block显示文摘The depositional and metamorphic ages and provenances of the Ailaoshan(ALS) Group in the Ailaoshan-Red River(ALS-RR) shear zone, southwestern South China Block(SCB), were investigated to constrain the tectonic history of the southwestern SCB. In this study, we use petrology, geochemical analysis, zircon cathodoluminescence imaging and UPb geochronology to analyse samples of quartzite, garnet-bearing two-mica schist and metapelite. The age spectra of detrital zircon grains from these metasediments show two dominant age peaks at 550–424 Ma and 876–730 Ma and two subordinate peaks at 970–955 Ma and ~2450 Ma. The youngest peak, corresponding to the early Palaeozoic, accounts for more than 20% of the total dates and constrains the deposition of the ALS Group to the Palaeozoic rather than the Palaeoproterozoic as traditionally thought. Moreover, two peaks of metamorphic ages corresponding to the Permo-Triassic and Cenozoic were also identified, and these ages document the tectonothermal events associated with the Indosinian collision between the Indochina Block and the SCB and the Himalayan collision between the Indian and Asian plates. Geochemical data suggest that the provenances of the ALS Group were dominated by continental arc and recycled metasedimentary rocks. The comparison of probability density distribution plots of the detrital zircon U-Pb age data indicates that the Neoproterozoic detritus in the ALS Group was probably derived from the arc-related Neoproterozoic intrusive bodies in the northwestern and southwestern SCB. Furthermore, the early Palaeozoic detritus might have been sourced from eroded early Palaeozoic strata and magmatic plutons in Cathaysia and volcanic rocks in the western Indochina Block. | JI Lei LIU Fulai WANG Fang TIAN Zhonghua | 2019 | Acta Geologica Sinica(English Edition)2019，93，6： | 4 |
| 8 | Effect of volatile oil from Blumea Balsamifera(L.) DC. leaves on wound healing in mice显示文摘OBJECTIVE: To assess the effectiveness of violateoil from Blumea Balsamifera(L.) DC. leaves(BB oil)on wound healing in mice.METHODS: Undiluted BB oil and its diluted solutions with olive oil to 1/5 and 1/10 to yield BB oil1/5and BB oil1/10 were applied to the wounded skin before wound healing conditions were assessed by healing rate, histopathology, and contents of collagen, hydroxyproline, and Neuropeptide Substance P(SP). All above results were compared with the efficacies of the control, pure olive oil, basic fibroblast growth factor(BFGF), and cream of Jing Wan Hong(JWH).RESULTS: BB oil1/5and BB oil1/10 improved wound contraction and closure. Histopathology study further confirmed a desirable histological organization of wound tissues. BB oil1/5and BB oil1/10 reduced the number of inflammatory cells, increased wound-healing rates, and significantly increased the hydroxyproline content. Both BB oil1/5and BB oil1/10 improved formation of collagen, and reduced the frequency of fibroblasts. Moreover, BB oil1/5and BB oil1/10 markedly promoted SP expression. However, undiluted BB oil may induce skin thickening and hardening, inhibite collagen synthesis and delay complete skin wound healing.CONCLUSION: The BB oil1/5and BB oil1/10 promoted capillary regeneration, blood circulation, collagen deposition, granular tissue formation, epithelial deposition, and wound contraction. The mechanism underlying the action might be related to induction of SP secretion, and the proliferation and differentiation of mesenchymal cells. | Yuxin Pang Dan Wang Xuan Hu Hui Wang Wanjin Fu Zuowang Fan Xiaolu Chen Fulai Yu | 2014 | Journal of Traditional Chinese Medicine2014，34，6： | 2 |
| 9 | Generalized fuzzy c-means clustering algorithm withimproved fuzzy partitions显示文摘 | ZHU LIN CHUNG FULAI WANG SHITONG | 2009 | IEEE Transactions on Systems Man and Cybernetics Part B:Cybernetics2009，39，3： | 1 |
| 10 | On minimum dis- tribution discrepancy support vector machine for domain adaotation显示文摘 | Tao Jianwen Chung Fulai Wang Shitong | 2012 | Pattern Recognition2012，45，11： | 1 |
| 11 | Kernel Density st,Kernel Methods,and Fast Learning in Large Data Sets显示文摘 | ang ShitongEimation Wang Jun Chun Fulai | 2014 | IEEE Transactions on Cybernetics2014，44，1： | 1 |
| 12 | Spatial differencing method for DOA estimation under the coexistence of both uncorrelated and coherent signals 显示文摘 | LIU Fulai WANG Jinkuan SUN Changyin | 2012 | IEEE Transactions on Antennas and Propagation2012，60，4： | 1 |
| 13 | On minimum class locality preserving variance support vector machine显示文摘 | WANG Xiaoming CHUNG Fulai WANG Shitong | 2010 | Patter recognition2010，43，8： | 1 |
| 14 | Theoretical choice of the optimal threshold for possibilistic linear model with noisy input显示文摘 | Ge Hongwei Chung Fulai Wang Shitong | 2008 | IEEE Transactions on Fuzzy Systems2008，16，4： | 1 |
| 15 | Kernel density esti- mation, kernel methods, and fast learning in large data sets显示文摘 | Wang Shitong Wang Jun Chnng Fulai | 2014 | IEEE Transactions on Cybernetics2014，44，1： | 1 |
| 16 | Genemlized fuzzy C-Means clustering algorithm with improved fuzzy partitions显示文摘 | Zhu Lin Chung Fulai Wang Shitong | 2009 | IEEE Transactions on Systerms Man and Cybernetics:Part B2009，39，3： | 1 |
| 17 | FRSDE:FastReduced Set Density Estimator Using Minimal Enclosing Ball显示文摘 | Deng Zhaohong Chung Fulai Wang Shitong | 2008 | Pattern Recognition2008，41，4： | 1 |
| 18 | Analysis of Volatile Components in Fresh Fruit of Morinda citrifolia L.from Different Origins Based on HS-SPME-GC/MS显示文摘[Objectives]This study was conducted to clarify the differences of volatile components in fresh fruit of Morinda citrifolia L.from different origins.[Methods]The method of HS-SPME-GC/MS detection was used to determine the volatile chemical components in fresh fruit of M.citrifolia.[Results]52,52 and 45 volatile components were identified from the fresh fruit of M.citrifolia from Xisha,Wanning and Haikou,respectively.Among them,the number and content of the identified esters were relatively high,mainly methyl caprylate,ethyl caprylate,4-pentenyl caproate,3-methylbuten-2-enyl caprylate,methyl caproate,and ethyl caproate.There were also fatty acids,alcohols,phenols,ketones,aldehydes and other substances.There were 33 common ingredients in the fruit from the three origins,mainly including caprylic acid,caproic acid,capric acid,methyl caprylate,ethyl caprylate,4-pentenyl caproate,3-methylbutene-2-enyl caprylate,methyl caproate,ethyl caproate,methyl caprate and hexyl caproate.[Conclusions]The types and contents of volatile components in fresh fruit of M.citrifolia from different origins were significantly different. | Dan WANG Qian JIANG Qinglong WANG Chao YUAN Maoyuan WANG Zuowang FAN Xiaolu CHEN Fulai YU | 2022 | Agricultural Biotechnology2022，11，4： | 1 |
| 19 | Blumeabalsamifera-A phyto- chemical and pharmacological review 显示文摘 | Pang Yuxin Wang Dan Yu Fulai | 2014 | Molecules2014，，19： | 1 |
| 20 | Multiple heat priming enhances thermo-tolerance to a later high temperature stress via improving subcellular antioxidant activities in wheat seedlings显示文摘 | Xiao Wang Jian Cai Fulai Liu Tingbo Dai Weixing Cao Bernd Wollenweber Dong Jiang | 2014 | Plant Physiology and Biochemistry2014，，： | 1 |
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