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| 1 | Lower time limit on the UHPM rock exhumation: Discovery of eclogite pebbles in the Late Jurassic conglomerates from the northern foot of the Dabie Mountains, eastern China显示文摘Eclogite pebbles are first discovered in late Jurassic conglomerates of the Fenghuangtai Formation from the northern foot of the Dabie Mountains, eastern China. The eclogite shows relatively strong retrograde metamor-phism. The major remnant minerals are garnet, phengite, quartz, rutile, clinozoisite, fingerprint(or worm)-form sym-plectite and pseudomorphic enclosure of coesite in garnet. End-member components of the garnet mainly made up of grossular (27.7%-37.8%), almandinc (45.5%-49.0%) and pyrope (12.3%-25.7%). End-member components of the pyrope is less than 30%, i.e. equivalent to C type eclogite. Si-cations of the phengite are 3.44-3.54 p.f.u. (taking O=11as standard). It is estimated that the pressures are 2.5-3.2 GPa, the temperatures are 600-900℃. Discovery of the eclogite pebbles in the late Jurassic conglomerates from the northern foot of the Dabie Mountains suggests that the HP-UHP metamorphic rocks of the Dabie Mountains, which were formed in Triassic, had been exposed to the surface in | Daoxuan Wang Yin Liu Shuangying Li Fuquan Jin | 2002 | Chinese Science Bulletin2002，47，3： | 19 |
| 2 | Analysis of Typical Automakers’ Strategies for Meeting the Dual-Credit Regulations Regarding CAFC and NEVs显示文摘The parallel corporate average fuel consumption(CAFC)and new energy vehicle(NEV)credit schemes that have been introduced by the Ministry of Industry and Information Technology of China is an innovative attempt to simultaneously regulate conventional gasoline vehicles(CGVs)and NEVs in the passenger vehicle sector that is expected to function as a long-term management mechanism for CGVs to be more energy-efficient and NEVs to be well-promoted.This will have a significant impact on trends in China’s automotive industry and automakers’business decisions.Taking the cases of four typical automakers with different levels of average fuel economy in their CGVs and advanced NEV production,scenario analysis has been applied to generate these automakers’alternatives in relation to compliance with the dual-credit regulations in force from 2017 to 2020 based on the Interim Measures on the Joint Management of CAFC and NEV Credits(Draft).These automakers’alternative approaches to compliance are compared.Further,in view of the financial losses as a result of halted production if they fail to comply,the values of CAFC and NEV credits and corresponding influencing factors are analyzed from the automakers’perspective.Finally,the most cost-effective compliance strategies for these automakers are summarized and suggested improvements in the regulations are proposed for the government. | Yue Wang Fuquan Zhao Yinshuo Yuan Han Hao Zongwei Liu | 2018 | Automotive Innovation2018，1，1： | 14 |
| 3 | Abating transport GHG emissions by hydrogen fuel cell vehicles: Chances for the developing world显示文摘 | Han HAO Zhexuan MU Zongwei LIU Fuquan ZHAO | 2018 | Frontiers in Energy2018，12，3： | 12 |
| 4 | Radiotherapy in combination with systemic therapies for brain metastases:current status and progress显示文摘Brain metastases(BMs)are the most common cause of intracranial neoplasms in adults with poor prognosis.Most BMs originate from lung cancer,breast cancer,or melanoma.Radiotherapy(RT),including whole brain radiotherapy(WBRT)and stereotactic radiation surgery(SRS),has been widely explored and is considered a mainstay anticancer treatment for BMs.Over the past decade,the advent of novel systemic therapies has revolutionized the treatment of BMs.In this context,there is a strong rationale for using a combination of treatments based on RT,with the aim of achieving both local disease control and extracranial disease control.This review focuses on describing the latest progress in RT as well as the synergistic effects of the optimal combinations of RT and systemic treatment modalities for BMs,to provide perspectives on current treatments. | Lei Liu Wanqi Chen Ruopeng Zhang Yuekun Wang Penghao Liu Xin Lian Fuquan Zhang Yu Wang Wenbin Ma | 2020 | Cancer Biology & Medicine2020，17，4： | 5 |
| 5 | Newly Discovered Native Gold and Bismuth in the Cihai Iron-Cobalt Deposit, Eastern Tianshan, Northwest China显示文摘The Cihai iron-cobalt deposit is located in the southern part of the eastern Tianshan ironpolymetallic metallogenic belt. Anomalous native gold and bismuth have been newly identified in Cinan mining section of the Cihai deposit. Ore formation in the deposit can be divided into three stages based on geological and petrographical observations:(I) skarn, with the main mineral assemblage being garnet-pyroxene-magnetite;(II) retrograde alteration, forming the main iron ores and including massive magnetite, native gold, native bismuth, and cobalt-bearing minerals, with the main mineral assemblage being ilvaite-magnetite-native gold-native bismuth; and(III) quartz-calcitesulfide assemblage that contains quartz, calcite, pyrrhotite, cobaltite, and safflorite. Native gold mainly coexists with native bismuth, and they are paragenetically related. The temperature of initial skarn formation was higher than 340℃, and then subsequently decreased to ~312℃ and ~266℃. The temperature of the hydrothermal fluid during the iron ore depositional event was higher than the melting point of native bismuth(271℃), and native bismuth melt scavenged gold in the hydrothermal fluid, forming a Bi-Au melt. As the temperature decreased, the Bi-Au melt was decomposed into native gold and native bismuth. The native gold and native bismuth identified during this study can provide a scientific basis for prospecting and exploration for both gold- and bismuth-bearing deposits in the Cihai mining area. The gold mineralization in Cihai is a part of the Early Permian Cu-Ni-Au-Fe polymetallic ore-forming event, and its discovery has implications for the resource potential of other iron skarn deposits in the eastern Tianshan. | ZHENG Jiahao MAO Jingwen YANG Fuquan CHAI Fengmei LIU Feng | 2016 | Acta Geologica Sinica(English Edition)2016，90，3： | 5 |
| 6 | Improving the cycle stability of FeCl3-graphite intercalation compounds by polar Fe2O3 trapping in lithium-ion batteries显示文摘FeCI3-intercalated graphite intercalation compounds (GICs) with high reversible capacity and high volumetric energy density are attractive anode material alternatives of commercial graphite. However, the rapid capacity decay, which was induced by chloride dissolution and shuttling issues, hindered their practical application. To address this problem, here, we introduce flake-like Fe2O3 species with inherently polar surface on the edge of FeCl3 -intercalated GICs through microwave-assisted transformation of a fraction of FeCl3 component. Theoretical simulations and physical/electrochemical studies demonstrate that the introduced Fe2O3 component can afford sufficient polar active sites for chemically bonding the soluble FeCl3 and LiCl species based on the polar-polar interaction mechanism, further inhibiting the outward diffusion of the chlorides and immobilizing them within the GIC material. In a lithium ion cell, the FeCl3 -intercalated GIC with a suitable Fe2O3 content shows remarkably improved cycling stability with a high reversible capacity of 1,041 mAh·g^-1 at a current density of 200 mA·g^-1. Capacity retention of 91 % is achieved at a high current density of 1,000 mA·g^-1 over 300 cycles. This work opens up the new prospect for immobilizing chlorides by introducing inorganic species in GIC for long-cycle electrochemical batteries. | Zheng Li Chengzhi Zhang Fei Han Fuquan Zhang Dianwu Zhou Shaohua Xu Hongbo Liu Xuanke Li Jinshui Liu | 2019 | Nano Research2019，12，8： | 4 |
| 7 | Electron-withdrawing functional ligand promotes CO2 reduction catalysis in single atom catalyst显示文摘Electrochemical carbon dioxide reduction reaction (CO2RR) powered by renewable electricity offers an attractive approach to reduce carbon emission and at the same time produce valuable chemicals/fuels.To design efficient CO2 reduction electrocatalyst,it is important to understand the structure-activity relationship.Herein,we design a series of single Co atoms electrocatalysts with well-defined active sites electronic structures,which exhibit outstanding CO2RR activity with controllable selectivity to CO.Experimental and density functional theory (DFT) calculation studies show that introducing nitro (amino) ligand next to single Co atom catalytic center with electron-withdrawing (electron-donating) capability favors (hinders) CO2 reduction catalysis.This work provides an in-depth understanding of how functional ligand affects the splitting of transition metal 3d electron orbital,thereby changing the electron transfer from transition metal active site to CO2,which is closely related to the Gibbs free energy of the rate-determining step (CO2+e^-+*→*CO2^-). | Xinyi Ren Song Liu Huicong Li Jie Ding Linghui Liu Zhichong Kuang Ling Li Hongbin Yang Fuquan Bai Yanqiang Huang Tao Zhang Bin Liu | 2020 | Science China Chemistry2020，63，12： | 3 |
| 8 | 雷公藤红素通过靶向核受体Nur77促进损伤线粒体自噬而抑制炎症反应显示文摘文章简介线粒体在细胞死亡、自噬、免疫和炎症中起着不可或缺的作用。前期研究发现,孤儿核受体Nur77通过靶向线粒体诱导细胞凋亡。本文报道了Nur77作为具有抗炎作用的雷公藤红素的直接靶点,介导雷公藤红素通过自噬清除损伤线粒体,抑制炎症反应而达到治疗炎症疾病包括肥胖症的功能。 | Mengjie Hu Qiang Luo Gulimiran Alitongbieke Shuyi Chong Chenting Xu Lei Xie Xiaohui Chen Duo Zhang Yuqi Zhou Zhaokai Wang Xiaohong Ye Lijun Cai Fang Zhang Huibin Chen Fuquan Jiang Hui Fang Shanjun Yang Jie Liu Maria T.Diaz-Meco Ying Su Hu Zhou Jorge Moscat Xiangzhi Lin 张晓坤 | 2018 | 科学新闻2018，0，4： | 3 |
| 9 | Effects of infusing milk precursors into the artery on rumen fermentation in lactating cows显示文摘This experiment was conducted to investigate the effects of infusing milk precursors into the external pudic artery on rumen fermentation in lactating dairy cows. Eight multiparous Holstein cows were randomly assigned to Group A(experimental group) and Group B(control group) with 4 cows each. A2×4 complex factor crossover design was used. Cows in Group A were fed corn straw as the only roughage, and cows in Group B were fed mixed roughage. The experiment was divided into two periods.In the first period, cows in Group A, received treatments: 1) a basal infusate as a control(CSC); 2) a milk fat precursor infusion including C16:0, C18:0, C18:1 c9, C18:2 c6, C18:3 n3, acetic acid(CSF); 3) a milk protein precursor infusion including 16 amino acids(CSA); 4) the mixed infusion of milk fat and protein precursors(CSFA). And meanwhile, cows in Group B were infused the basal infusate as a control group. In the second period, the cows in both Groups A and B were crossed over, which cows in Group A were named as Group B and the cows originally in Group B were in Group A. The experimental results showed that cows in experimental group had higher ruminal pH compared with the control, and ruminal pH in CSC, CSF, CSA were significantly higher than those in their respective control group(P < 0.05). The concentration of ammonia nitrogen(NH_3-N) was significantly higher in CSA and CSFA compared with Group B(P < 0.05). We also observed that the infusion of mixed amino acids significantly increased the bacterial protein(BCP) content in rumen(P < 0.05) and influenced the rumen acetic acid concentration as well as the acetic to propionic ratio(P < 0.05). Milk fat precursors infusion significantly affected butyric acid concentration(P < 0.05). In addition, the content of lipopolysaccharide(LPS) in CSA was significantly higher than that in the control group(P < 0.05). It is concluded that the milk precursors infused into external pudic artery caused feedback effects on ruminal fermentation under the corn straw roughage conditions. The milk protein precursor increased the ruminal pH, the contents of BCP and acetic acid, which adjust rumen fermentation and improve milk performance. | Xianjue Wang Changjin Ao Khas-Erdene Shuaiwang Liu Chen Bai Fuquan Zhang Ying Zhang Peng Gao | 2016 | Animal Nutrition2016，，2： | 3 |
| 10 | Carpel of cucumber (Cucumis sativus. L) male flowers maintains early primordia characteristics during organ development显示文摘Diclinism is not only an interesting natural phenomenon in plant kingdom, but also of significance in the yield of crops, e.g. cucumber and watermelon. Cucumber has been a model plant for studying the diclinism for decades. However, it is stili obscure how the carpel primordia of cucumber male flower undergo the developmental processes after the initiation of their development. By showing morphological alternation, metabolic activity, as well as CFL gene expression, the present study demonstrated that the carpel primordia of cucumber male flowers maintained the characteristics of primordium until anthesis, although it developed significantly slower than that of the female flowers. | YANG Lingling CHEN Min LIU Fuquan GENG Yi CHEN Chong LI Yiqin CAO Zongxun XU Zhihong BAI Shunong | 2000 | Chinese Science Bulletin2000，45，8： | 3 |
| 11 | Alisol B 23-acetate-induced HepG2 hepatoma cell death through mTOR signaling-initiated G_1 cell cycle arrest and apoptosis: A quantitative proteomic study显示文摘Objective: The present study aimed to investigate the molecular events in alisol B 23-acetate(ABA) cytotoxic activity against a liver cancer cell line.Methods: First, we employed a quantitative proteomics approach based on stable isotope labeling by amino acids in cell culture(SILAC) to identify the different proteins expressed in HepG2 liver cancer cells upon exposure to ABA. Next, bioinformatics analyses through DAVID and STRING on-line tools were used to predict the pathways involved. Finally, we applied functional validation including cell cycle analysis and Western blotting for apoptosis and mTOR pathway-related proteins to confirm the bioinformatics predictions.Results: We identified 330 different proteins with the SILAC-based quantitative proteomics approach. The bioinformatics analysis and the functional validation revealed that the mTOR pathway, ribosome biogenesis, cell cycle, and apoptosis pathways were differentially regulated by ABA. G1 cell cycle arrest, apoptosis and mTOR inhibition were confirmed.Conclusions: ABA, a potential mTOR inhibitor, induces the disruption of ribosomal biogenesis. It also affects the mTOR-MRP axis to cause G1 cell cycle arrest and finally leads to cancer cell apoptosis. | Ji Xia Qiang Luo Shengbin Huang Fuquan Jiang Lin Wang Guanghui Wang Jingjing Xie Jie Liu Yang Xu | 2019 | Chinese Journal of Cancer Research2019，31，2： | 2 |
| 12 | Comparative analysis by simulating and testing pole impact for hot stamping front crossbeam of automobile显示文摘Hot stamping 22MnB5 steel plate with ultra-high strength has been widely used for body structural members in consideration of automobile safety and lightweight.This paper presents a verification program of simulating and testing pole impact in order to verify if the front crossbeam reinforcement assembly can meet the design requirements,reduce the overall vehicle simulation and test cost and shorten the operation period.In the same condition,the simulation proved conforming to the design requirements;however,the bumper cracked at the impacting point in the course of pole impact test.The analysis of the crack by optical microscope,Vickers and scanning electron microscope indicates that mixture of ferrite,bainite and martensite was produced in the weld heat-affected zone of the 340/590DP tow hook holder and the 22MnB5 front crossbeam;therefore,their hardness and mechanical property were reduced obviously,so that they fractured when impacted.No welding process with continuous weld but spot welding or other bonding method may be employed for the reason that the capacity of the 22MnB5 steel plate in the weld heat-affected zone was reduced obviously. | Ma Fangwu Yao Zaiqi Liu Qiang Wang Xiaona Zhao Fuquan Li Fangfang Lin Jianping | 2012 | Engineering Sciences2012，10，6： | 2 |
| 13 | Impact,Challenges and Prospect of Software-Defined Vehicles显示文摘Software-defined vehicles have been attracting increasing attentions owing to their impacts on the ecosystem of the automo-tive industry in terms of technologies,products,services and enterprise coopetition.Starting from the technology improve-ments of software-defined vehicles,this study systematically combs the impact of software-defined vehicles on the value ecology of automotive products and the automotive industrial pattern.Then,based on the current situation and demand of industrial development,the main challenges hindering the realization of software-defined vehicles are identified,including that traditional research and development models cannot adapt to the iterative demand of new automotive products;the transformation of enterprise capability faces multiple challenges;and many contradictions exist in the industrial division of labor.Finally,suggestions are put forward to address these challenges and provide decision-making recommendations for enterprises on strategy management. | Zongwei Liu Wang Zhang Fuquan Zhao | 2022 | Automotive Innovation2022，5，2： | 2 |
| 14 | Electron microscopy study of reaction layers between single-crystal WC particle and Ti–6Al–4V after laser melt injection显示文摘 | Liqun Li Dejian Liu Yanbin Chen Chunming Wang Fuquan Li | 2009 | Acta Materialia2009，，12： | 1 |
| 15 | WC p /Ti–6Al–4V graded metal matrix composites layer produced by laser melt injection显示文摘 | Yanbin Chen Dejian Liu Fuquan Li Liqun Li | 2008 | Surface & Coatings Technology2008，，19： | 1 |
| 16 | WCp/Fe metalmatrix composites produced by laser melt injection显示文摘 | LIU Dejian LI Liqun LI Fuquan | 2008 | Surface&Coatings Technology2008，202，9： | 1 |
| 17 | Research on plastic fender development and key technologies显示文摘Automotive lightweight and safety performance come into play as key technologies to promote competiveness, and average applied amount of automotive plastics has become a significant sign for automotive industrial development level of a country.Various performances of a vehicle with plastic automotive fenders are analyzed in the paper.The research is emphasized on sinking-resistance and pedestrian protection performance of the plastic fenders by studying plastics characteristics and simulation analysis.It offers references for engineering design in which both automotive lightweight and safety performance are achieved and well balanced. | Yang Hao Li Li Liu Qiang Yang Anzhi Ma Fangwu Zhao Fuquan Guo Yihui Song Leifeng | 2012 | Engineering Sciences2012，10，6： | 1 |
| 18 | WC~JFe metal matrix composites produced by laser melt injection 显示文摘 | Liu Dejian Li Liqun Li Fuquan | 2008 | Surface & Coatings Technology2008，202，： | 1 |
| 19 | Clustered DNA damage induced by protons radiation in plasmid DNA显示文摘Clustered DNA damage is considered as a critical type of lesions induced by ionizing radiation, which can be converted into the fatal or strong mutagenic complex double strand breaks (DSBs) during damage processing in the cells. The new data show that high energy protons produce more potentially lethal DSBs than low LET radiation. In this study, plasmid DNA were used to in-vestigate and re-evaluate the biological effects induced by the protons with the LET of ~3.6 keV/μm at the molecular level in vitro, including single strand breaks (SSBs), DSBs, isolated and clustered base damages. The results of complex DNA damage detections indicated that protons at the given LET value induce about 1.6 fold more non-DSB clustered DNA damages than the prompt DSB. The DNA damage yields by protons were greater than that by γ-rays, specifically by 6 fold for the isolated type of DNA damage and 14 fold for the clustered damage. Furthermore, the spectrum of damages was also demonstrated to be depended on the radiation quality, with protons producing more DSBs relative to clusters than do γ-rays. | SUI Li WANG Yu WANG Xiao KONG FuQuan LIU JianCheng ZHOU PingKun | 2013 | Chinese Science Bulletin2013，58，26： | 1 |
| 20 | The comparition of biological characteristics and multilineage differentiation of bone marrow and adipose derived Mesenchymal stem cells显示文摘 | Xishan Zhu Wei Shi Weiping Tai Fuquan Liu | 2012 | Cell and Tissue Research2012，，2： | 1 |
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