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| 1 | Lentinan prolonged survival in patients with gastric cancer receiving S-1-based chemotherapy显示文摘AIM:To examine whether administration of lentinan,purifiedβ-1,3-glucan,can prolong survival in advanced gastric cancer patients receiving S-1-based chemotherapy.METHODS:Since 2004,78 patients with metastatic or recurrent gastric cancer have received S-1-based chemotherapy as first-line treatment.Survival,side effects,and the ratio of granulocytes/lymphocytes(G/L ratio)were compared between 2 groups of patients who received chemo-immunotherapy using lentinan and chemotherapy alone.RESULTS:Median overall survival was significantly longer in the former group than in the latter group[689 d(95%CI:431-2339 d)vs 565 d(95%CI:323-662 d),P=0.0406].In addition,the G/L ratio in patients who received lentinan was maintained around or below 2,which was significantly lower than that in patients who received chemotherapy alone(P<0.001).CONCLUSION:Chemo-immunotherapy with lentinan offers a significant advantage over S-1-based chemotherapy alone in terms of survival in patients with advanced gastric cancer. | Kenji Ina Ryuichi Furuta Takae Kataoka Satoshi Kayukawa Takashi Yoshida Takaya Miwa Yoshitaka Yamamura Yuuki Takeuchi | 2011 | World Journal of Clinical Oncology2011，2，10： | 10 |
| 2 | Inverted Meckel's diverticulum preoperatively diagnosed using double-balloon enteroscopy显示文摘An inverted Meckel's diverticulum is a rare gastrointestinal congenital anomaly that is difficult to diagnose prior to surgery and presents with anemia, abdominal pain, or intussusception. Here, we report the case of 57-year-old men with an inverted Meckel's diverticulum, who was preoperatively diagnosed using doubleballoon enteroscopy. He had repeatedly experienced epigastric pain for 2 mo. Ultrasonography and computed tomography showed intestinal wall thickening in the pelvis. Double-balloon enteroscopy via the anal route was performed for further examination, which demonstrated an approximately 8-cm, sausage-shaped, submucosal tumor located approximately 80 cm proximal to the ileocecal valve. A small depressed erosion was observed at the tip of this lesion. Forceps biopsy revealed heterotopic gastric mucosa. Thus, the patient was diagnosed with an inverted Meckel's diverticulum, and single-incision laparoscopic surgery was performed. This case suggests that an inverted Meckel's diverticulum should be considered as a differential diagnosis for a submucosal tumor in the ileum. Balloon-assisted enteroscopy with forceps biopsy facilitate a precise diagnosis of this condition. | Kosuke Takagaki Satoshi Osawa Tatsuhiro Ito Moriya Iwaizumi Yasushi Hamaya Hiroe Tsukui Takahisa Furuta Hidetoshi Wada Satoshi Baba Ken Sugimoto | 2016 | World Journal of Gastroenterology2016，22，17： | 2 |
| 3 | Ability of Rabeprazole to Prevent Gastric Mucosal Damage From Clopidogrel and Low Doses of Aspirin Depends on CYP2C19 Genotype显示文摘 | Takahiro Uotani Mitsushige Sugimoto Masafumi Nishino Chise Kodaira Mihoko Yamade Shu Sahara Takanori Yamada Satoshi Osawa Ken Sugimoto Tatsuo Tanaka Kazuo Umemura Hiroshi Watanabe Hiroaki Miyajima Takahisa Furuta | 2012 | Clinical Gastroenterology and Hepatology2012，，8： | 2 |
| 4 | Tuberous sclerosis patient with neuroendocrine carcinoma of the esophagogastric junction:A case report显示文摘BACKGROUND Tuberous sclerosis complex(TSC)is a rare inherited disease with non-cancerous tumor growths in the skin,brain,kidneys,heart,and lungs.The co-occurrence of neuroendocrine neoplasm(NEN)with TSC is even rarer.There have been few reports on the relationship between TSC and neuroendocrine tumors(NETs),and fewer on the relationship between TSC and neuroendocrine carcinoma(NEC),a subtype of NEN.This is the first reported case of NEC occurring at the esophagogastric junction in a patient with TSC.CASE SUMMARY A 46-year-old woman visiting our hospital for the treatment of TSC was admitted to the emergency department with tarry stools and dizziness.Computed tomography scans revealed thickness of the gastric cardia,multiple metastatic lesions of the liver,and enlarged lymph nodes near the lesser curvature of the stomach.Esophagogastroduodenoscopy revealed a type 3 tumor located from the esophagogastric junction to the fundus,and the pathological diagnosis by biopsy was NEC.The patient was treated with seven courses of cisplatin+irinotecan,followed by eight courses of ramucirumab+nab-paclitaxel,one course of nivolumab,and two courses of S-1+oxaliplatin.Twenty-three months after the first treatment,the patient died because of disease progression and deterioration of the general condition.CONCLUSION This case of NEC occurring in a patient with TSC indicates a difference in the occurrence of NETs and NECs. | Natsuki Ishida Takahiro Miyazu Satoshi Tamura Satoshi Suzuki Shinya Tani Mihoko Yamade Moriya Iwaizumi Satoshi Osawa Yasushi Hamaya Kazuya Shinmura Haruhiko Sugimura Katsutoshi Miura Takahisa Furuta Ken Sugimoto | 2020 | World Journal of Gastroenterology2020，26，45： | 2 |
| 5 | A case of small bowel adenocarcinoma in a patient with Crohn’s disease detected by PET/CT and double-balloon enteroscopy显示文摘Small bowel adenocarcinoma (SBA) in patients with Crohn’s disease (CD) is quite rare, difficult to diagnose without surgery, and has a poor prognosis. Here, we report a 48-year-old man with SBA and a 21-year history of CD who was diagnosed by a combination of positron emission tomography/computed tomography (PET/CT) and double-balloon enteroscopy (DBE). Since the age of 27 years, the patient had been treated for ileal CD and was referred to our hospital with persistent melena. Multiple hepatic tumors were found by CT. PET/CT detected an accumulation spot in the small bowel. DBE revealed an ulcerative tumor in the ileum about 100 cm from the ileocecal valve. An endoscopic forceps biopsy specimen showed poorly differentiated adenocarcinoma. There were some longitudinal ulcer scars near the tumor, and the chronic inflammation inthe small bowel appeared to be associated with the cancer development. Previous reports suggest the risk of SBA in patients with CD is higher than in the overall population. Since early diagnosis is extremely difficult in these cases, novel techniques, such as PET/CT and DBE, may be expected to help in making a preoperative diagnosis of the development of SBA in CD. | Chise Kodaira Satoshi Osawa Chihiro Mochizuki Yoshihiko Sato Masafumi Nishino Takanori Yamada Yasuhiro Takayanagi Kosuke Takagaki Ken Sugimoto Shigeru Kanaoka Takahisa Furuta Mutsuhiro Ikuma | 2009 | World Journal of Gastroenterology2009，15，14： | 2 |
| 6 | Catalytic action of sulfated tin oxide for etherification and esterification in comparison with sulfated zirconia显示文摘 | Satoshi Furuta Hiromi Matsuhashi Kazushi Arata | 2004 | Applied Catalysis A:General2004，269，18： | 1 |
| 7 | Biodiesel fuel production with solid superacid catalysis in fixed bed reactor under atmospheric pressure 显示文摘 | Satoshi Furuta Himmi Matsuhashi Kazushi Arata | 2004 | Catalysis Communications2004，5，12： | 1 |
| 8 | Sitafloxacin‐based third‐line rescue regimens for H elicobacter pylori infection in J apan显示文摘 | Takahisa Furuta Mitsushige Sugimoto Chise Kodaira Masafumi Nishino Mihoko Yamade Takahiro Uotani Shu Sahara Hitomi Ichikawa Takanori Yamada Satoshi Osawa Ken Sugimoto Hiroshi Watanabe Kazuo Umemura | 2014 | J Gastroenterol Hepatol2014，，3： | 1 |
| 9 | Biodiesel fuel production with solid superacid catalysis in fixed bed reactor under atmospheric pressure 显示文摘 | Furuta Satoshi Matsuhashi Hiromi Arata Kazushi | 2004 | Catalysis Communications2004，5，12： | 1 |
| 10 | Catalytic action of sulfated tin oxide for etherification and esterification in comparison with sulfated zirconia显示文摘 | Satoshi Furuta Hiromi Matsuhashi Kazushi Arata | 2004 | Applied Catalysis A:General2004，269，： | 1 |
| 11 | Biodiesel fuel production with solid amorphous-zirconia catalysis in fixed bed reactor显示文摘 | Satoshi Furuta Hiromi Matsuhashi Kazushi Arata | 2006 | Biomass and Bioenergy2006，，： | 1 |
| 12 | Biodie- sel fuel production with solid superacid catalysis in fixed bed reactor under atmospheric pressure 显示文摘 | Satoshi Furuta Hiremi Matsuhashi Kazushi Arata | 2004 | Catalysis Communications2004，5，12： | 1 |
| 13 | Biodiesel fuel production with solid amorphous-zirconia catalysis in fixed bed reactor显示文摘 | Furuta Satoshi Matsuhashi Hiromi Arata Kazushi | 2006 | Biomass and Bioenergy2006，30，10： | 1 |
| 14 | Biodiesel Fuel Production with Solid Superacid Catalysis in Fixed Bed Reactor under Atmospheric Pressure显示文摘 | Satoshi Furuta Hiromi Matsuhashi | 2004 | Catalysis Communications2004，5，： | 1 |
| 15 | Catalytic action of sulfated tin oxide for etherification and esterification in comparison with sulfated zirconia显示文摘 | Satoshi Furuta Hiromi Matsuhashi Kazushi Arata | 2004 | Applied Catalysis A General2004，，1： | 1 |
| 16 | Clinical characteristics of Japanese patients with eosinophilic esophagitis and eosinophilic gastroenteritis显示文摘 | Yoshikazu Kinoshita Kenji Furuta Norihisa Ishimaura Shunji Ishihara Shuichi Sato Riruke Maruyama Shuichi Ohara Takayuki Matsumoto Choitsu Sakamoto Toshiyuki Matsui Satoshi Ishikawa Tsutomu Chiba | 2013 | Journal of Gastroenterology2013，，3： | 1 |
| 17 | Biodiesel fuel production with solid superacid catalysis in fixed bed reactor under atmospheric pressure显示文摘 | Furuta Satoshi Matsuhashi Hiromi Arata Kazushi | 2004 | Catalysis Communications2004，，5： | 1 |
| 18 | Catalytic action of sulfated tin oxide for etherification and esterification in comparison with sulfated zirconia显示文摘 | Satoshi Furuta Hiromi Matsuhashi Kazushi Arata | 2004 | Applied Catalysis A:General2004，269，12： | 1 |
| 19 | Debittering of enzymatic hydrolysates using an aminopeptidase from the edible basidiomycete gribla frondosa 显示文摘 | Toshikazu N Satoshi Y Michio Furuta | 2002 | Journal of Bioscience and Bioengineer2002，93，1： | 1 |
| 20 | Biodiesel fuel production with solid superacid catalysis in fixed bed reactor under atmospheric pressure 显示文摘 | Furuta Satoshi Matsuhashi Hiromi Arata Kazushi | 2005 | Catalysis Communications2005，5，12： | 1 |
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