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    题名 作者 年代 出处 被引量
12019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W 2020中华高血压杂志2020,28,3:516
2Assessment of the uncertainties in temperature change in China during the last century显示文摘We have used the China Homogenized Historic Temperature dataset and some long-term station series of the neighbor countries from CRUTEM3,a 5°×5° gridded dataset of monthly mean temperature since 1900,to provide a 107-year record of surface temperature trends and variability.We derived a comprehensive set of uncertainty estimates to accompany the data:measurement and sampling errors,uncertainties in temperature bias estimates,and uncertainties arising from limited observational coverage on large-scale averages have all been estimated.We reanalysed the temperature changes during the period of record.The best estimates of trends for 1900-2006 with uncertainties at 95% confidence range are about 0.09±0.017°C/decade for the year as a whole,and 0.14±0.021°C/decade,0.11±0.021°C/decade,0.04±0.017°C/decade,and 0.07±0.017°C/decade for winter,spring,summer and autumn respectively.For 1954-2006,the trends for annual,winter,spring,summer and autumn are:0.26±0.032°C/decade,0.35±0.046°C/decade,0.25±0.051°C/decade,0.16±0.037°C/decade and 0.22±0.055°C/decade.Winter saw the most significant warming trend in both 1900-2006 and 1954-2006,while during the most recent period(the satellite era,1979-2006),all the seasons show similar warming trends:0.45±0.13°C/decade,0.51±0.11°C/decade,0.52±0.16°C/decade,0.37±0.10°C/decade and 0.50±0.16°C/decade for annual,winter,spring,summer and autumn.Trends arising from urbanization have been evaluated as less than 5% of the total warming trend for 1951-2001,so this bias was not removed.LI QingXiang DONG WenJie LI Wei GAO XiaoRong JONES P KENNEDY J PARKER D 2010Chinese Science Bulletin2010,55,19:26
3烟酰胺磷酸核糖基转移酶促进肺血管重塑,是肺动脉高压的治疗靶点显示文摘肺动脉高压(pulmonary arterial hypertension,PAH)是一种严重的进行性疾病,其标志之一是肺血管重塑。烟酰胺磷酸核糖基转移酶(nicotinamide phosphoribosyl transferase,NAMPT)是调节细胞内烟酰胺腺嘌呤二核苷酸水平、细胞氧化还原状态,调节组蛋白脱乙酰酶,促进细胞增殖和抑制凋亡的一种细胞酶。研究人员假设NAMPT可促进肺血管重塑,Chen J Sysol JR Singla S Zhao S Yamamura A Valdez-Jasso D Abbasi T Shioura KM Sahni S Reddy V Sridhar A Gao H Torres J Camp SM Tang H Ye SQ Comhair S Dweik R Hassoun P Yuan JX Garcia JG Machado RF 刘莉 叶鹏 2017中华高血压杂志2017,25,2:10
4Adipocyte iron regulates adiponectin and insulin sensitivity显示文摘Gabrielsen J Scott Gao Yan Simcox Judith A Huang Jingyu Thorup David Jones Deborah Cooksey Robert C Gabrielsen David Adams Ted D Hunt Steven C Hopkins Paul N Cefalu William T McClain Donald A 2012EN2012,,10:2
5A high-sensitivity quantitative PCR platform 显示文摘DeGraves F J Gao D Kaltenboeck B 2003BioTechniques2003,34,:1
6A framework to integrate design knowledge reuse and requirements management in engineering design显示文摘BAXTER D GAO J CASE K 2008Robotics and Computer-lntegrated Manufacturing2008,24,4:1
7Association of NFKBIA polymorphism with colorectal cancer risk and prognosis in Swedish and Chinese populations显示文摘Gao J Pfeifer D He i J 2007Scand J Gastroenterol2007,42,3:1
8Phase-contrast imaging of weakly absorbing materials using hard x-rays显示文摘Davis T J Gao D 1995Nature1995,373,:1
9Method of formation classification while drilling with PDC bits显示文摘GAO D ZHANG H WANG J 1998Acta Optica Sinica1998,18,1:1
10Screening for anti-lipase prop- erties of 37 traditional Chinese medicinal herbs显示文摘Zheng C D Duan Y Q Gao J M 2010J Chin Med Assoc2010,73,6:1
11Influence of thermal loading on the dynamic response of thin-walled struc- ture under thermo-acoustic loading 显示文摘Sha Y D Gao Z J Xu F 2011Applied Me- chanics and Materials2011,,23:1
12TSC1 and TSC2 tumor suppres-sors antagonize insulin signaling in cell growth 显示文摘GAO X PAN D J 2001Genes Dev2001,15,:1
13Capability of SPOT XS Data in Pro- ducing Detailed Land Cover Maps at the Urban-rural Periphery显示文摘Gao J Skillcorn D 1998International Journal of Remote Sensing1998,19,15:1
14Genetic control of rice plant architecture under domestication 显示文摘Jin J Huang W Gao J Yang J Shi M Zhu M Luo D Lin H 2008Nature Genetics2008,40,11:1
15Cyclovirobuxine D induces autophagy-associated cell death via the Akt/m TOR pathway in MCF-7 human breast cancer cells显示文摘Lu J Sun D Gao S 2014J Pharmacol Sci2014,125,1:1
16Kaempferol and quercetin isolated from Euonymus alatus improve glucose uptake of 3T3-L1 cells without adipogenesis activity显示文摘FANG X GAO J ZHU D 2008Life Sci2008,,:1
17Indentation size effects in crystalline materials: a law for strain gradient plasticity显示文摘Nix W D Gao H J 1998J Mech Phys Solids1998,46,3:1
18Solution conformation of brazzein by 1H nuclear magnetic resonance:resonance assignent and secondary structure 显示文摘 Dia J X Ming D 1999International Journal of Biological Macromolecules1999,24,:1
19The effects of pre-oxidation and thin Y2 03 coating on the selective oxidation of Cr18-Nig- Ti steel 显示文摘Ma J He Y D Wang D R Gao W 2004Materials Letters2004,58,5:1
20Nasopharyngeal carcinoma treated by radical radiotherapy alone: ten year experience of a single institution显示文摘Yi J L Gao L Huang X D 2006Int J Radiat Oncol Biol Phys2006,65,1:1
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