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1Dihydroartemisinin is an inhibitor of ovarian cancer cell growth显示文摘瞄准:调查 dihydroartemisinin (DHA ) 的反癌症活动,在人的卵巢的癌症房间的一块面板的反疟疾药 artemisinin 的衍生物排队。方法: 房间生长被 MTT 生存能力试金决定。Apoptosis 和房间周期前进被 DNA 破碎胶化电气泳动,流动 cytometry 试金,和 TUNEL 试金评估;蛋白质和 mRNA 表示被西方的弄污和 RT-PCR 试金分析。结果:Artemisininand 它的衍生物包括 artesunate, arteether, artemether, arteannuin,和 DHA,在人的卵巢的癌症细胞的 exhibitanticancer 生长活动。在他们之中, DHA 在禁止房间生长是最有效的。卵巢的癌症房间线是更敏感的(5-10-fold ) 到与正常相比的 DHA 治疗,卵巢的房间排队。在微臼齿的剂量层次的 DHA 展出剂量 -- 在卵巢的癌症房间的 andtime 依赖的 cytotoxicity 排队。而且, DHA 导致了 apoptosis 和 G2cell 周期拘捕,由 Bcl-xL 和 Bcl-2 和 Bax 和 Bad.Conclusion 的增加的减少伴随了:有希望的结果第一次证明 DHA 禁止人的卵巢的癌症房间的生长。房间生长, apoptosis 正式就职,和 G2 拘捕在卵巢的癌症的临床的治疗作为可能的反癌症药为 DHA 的进一步的研究在 vitro 证据提供的卵巢的癌症的选择抑制。Yang JIAO Chun-min GE Qing-hui MENG Jian-ping CAO Jian TONG Sai-jun FAN 2007Acta Pharmacologica Sinica2007,28,7:39
2Resveratrol Induces Apoptosis and Autophagy in T-cell Acute Lymphoblastic Leukemia Cells by Inhibiting Akt/mTOR and Activating p38-MAPK显示文摘Objective To explore the effects of resveratrol-induced apoptosis and autophagy in T-cell acute lymphoblastic leukemia(T-ALL) cells and potential molecular mechanisms. Methods The anti-proliferation effect of resveratrol-induced, apoptosis and autophagy on T-ALL cells were detected by using MTT test, immunofluorescence, electronic microscope, and flow cytometry, respectively. Western blotting was performed for detecting changes of apoptosis-associated proteins, cell cycle regulatory proteins and state of activation of Akt, mTOR, p70S6K, 4E-BP1, and p38-MAPK. Results Resveratrol inhibited the proliferation and induced apoptosis and autophagy in T-ALL cells in a dose and time-dependent manner. It also induced cell cycle arrest at G0/G1 phase via up regulating cyclin-dependent kinase(CDK) inhibitors p21 and p27 and down regulating cyclin A and cyclin D1. Western blotting revealed that resveratrol significantly decreased the expression of antiapoptotic proteins(Mcl-1 and Bcl-2) and increased the expression of proapoptotic proteins(Bax, Bim, and Bad), and induced cleaved-caspase-3 in a time-dependent manner. Significant increase in ratio of LC3-II/LC3-I and Beclin 1 was also detected. Furthermore, resveratrol induced significant dephosphorylation of Akt, mTOR, p70S6K, and 4E-BP1, but enhanced specific phosphorylation of p38-MAPK which could be blocked by SB203580. When autophagy was suppressed by 3-MA, apoptosis in T-ALL cells induced by resveratrol was enhanced.Conclusion Our findings have suggested that resveratrol induces cell cycle arrest,apoptosis,and autophagy in T-ALL cells through inhibiting Akt/mTOR/p70S6K/4E-BP1 and activating p38-MAPK signaling pathways.Autophagy might play a role as a self-defense mechanism in T-ALL cells treated by resveratrol.Therefore,the reasonable inhibition of autophagy in T-ALL cells may serve as a promising strategy for resveratrol induced apoptosis and can be used as adjuvant chemotherapy for T-ALL.GE Jiao LIU Yan LI Qiang GUO Xia GU Ling MA Zhi Gui ZHU Yi Ping 2013Biomedical and Environmental Sciences2013,26,11:38
3Adenovirus-mediated expression of Tob1 sensitizes breast cancer cells to ionizing radiation显示文摘瞄准:调查 Tob1 基因的效果, ErbB2/B-cell 易位 Ggene (TOB/BTG ) 家庭的 Transducing 分子的一个成员,由在一个人在放射敏感度上使用 Tob1 的调停侵入人体气管粘膜的病菌的表示,乳癌房间衬里 MDA-MB-231。方法:房间幸存被 clonogenic 试金决定。Apoptosis 被 DNA 破碎胶化电气泳动和终端 deoxynucleotidyl 评估调停 transferase 的刻痕结束标记试金。蛋白质表示被西方的污点试金分析, DNA 修理被主人房间复活试金测量。结果:我们证明有 Ad5-Tob1 的照耀前治疗显著地增加了放射敏感度,伴随 apoptosis 的增加的正式就职和 DNA 损坏修理的压抑。而且, Ad5-Tob1-mediated 放射敏感度相关与起来 pro-apoptotic 蛋白质 Bax 的规定并且下面几 DNA 双海滨裂缝修理蛋白质,包括的 DNA 依赖的蛋白质家族 ases, Ku70 和 Ku80 的规定,和 X-ray-sensitive 互补组织 4。结论:作为新收音机抗体, Tob1 是在经由增加 apoptosis 并且压制 DNA 修理的乳癌的放射疗法的一个新目标。Yang JIAO Chun-min GE Qing-hui MENG Jian-ping CAO Jian TONG Sai-jun FAN 2007Acta Pharmacologica Sinica2007,28,10:12
4Bartonella Species Detected in the Plateau Pikas(Ochotona curzoiae) from Qinghai Plateau in China显示文摘Bartonella 种类能感染许多哺乳动物的主人并且在人引起许多疾病,但是在那里有不是在 Ochotonidae 的 Bartonella 感染的报告。这是第一研究在 Qinghai 高原在高原一种短耳野兔检测 Bartonella,提供为对在这个区域的人的 Bartonella 感染的风险评价的基线数据。我们与 18.99% 的积极的率在 Qinghai 的 Binggou 和 Maixiu 区域从 79 只一种短耳野兔获得了 15 Bartonella 紧张。基于基因定序的 Bartonella 柠檬酸盐 synthase (gltA ) 的种系发生的分析,大多数紧张是仔细与 B 有关。taylorii (3/15 ) 和 B。grahamii (12/15 ) 。后者是在人的病原的紧张。我们的结果建议相应预防和控制策略应该在 Qinghai 省被考虑。RAO Hua Xiang YU Juan GUO Peng MA Yong Cheng LIU Qi Yong JIAO Ming MA Zhong Wen GE Hua WANG Chun Xiang SONG Xiu Ping SHI Yan LI Dong Mei 2015Biomedical and Environmental Sciences2015,28,9:8
5Hydrogen-rich saline protects against hepatic injury induced by ischemia-reperfusion and laparoscopic hepatectomy in swine显示文摘Background: Hydrogen-rich saline(HRS) has antioxidative, anti-inflammatory and anti-apoptotic properties. We investigated the effects of hydrogen on hepatic ischemia-reperfusion(I/R) and laparoscopic hepatectomy in swine. Methods: Twenty-one healthy Bama miniature pigs were randomly divided into the sham group, ischemia-reperfusion injury(IRI) group, HRS-5(5 m L/kg) group, and HRS-10(10 m L/kg) group. HRS was injected through the portal vein 10 min before reperfusion and at postoperative day 1, 2 and 3. The roles of HRS on oxidative stress, inflammatory response and liver regeneration were studied. Results: Compared with the IRI group, HRS treatment attenuated oxidative stress by increasing catalase activity and reducing myeloperoxidase. White blood cells in the HRS-10 group were reduced compared with the IRI group( P < 0.01). In the HRS-10 group, interleukin-1 beta, interleukin-6 and tumor necrosis factor alpha, C-reactive protein and cortisol were downregulated, whereas interleukin-10 was upregulated. In addition, HRS attenuated endothelial cell injury and promoted the secretion of angiogenic cytokines, including vascular endothelial growth factor, angiopoietin-1 and angiopoietin-2. HRS elevated the levels of hepatocyte growth factor, Cyclin D1, proliferating cell nuclear antigen, Ki-67 and reduced the secretion of transforming growth factor-beta. Conclusions: HRS treatment may exert a protective effect against I/R and hepatectomy-induced hepatic damage by reducing oxidative stress, suppressing the inflammatory response and promoting liver regeneration.Yan-Song Ge Qian-Zhen Zhang Hui Li Ge Bai Zhi-Hui Jiao Hong-Bin Wang 2019Hepatobiliary & Pancreatic Diseases International2019,18,1:8
6Spatial pattern of grassland aboveground biomass and its environmental controls in the Eurasian steppe显示文摘Vegetation biomass is an important component of terrestrial ecosystem carbon stocks. Grasslands are one of the most widespread biomes worldwideplaying an important role in global carbon cycling. Thereforestudying spatial patterns of biomass and their correlations to environment in grasslands is fundamental to quantifying terrestrial carbon budgets. The Eurasian steppean important part of global grasslandsis the largest and relatively well preserved grassland in the world. In this studywe analyzed the spatial pattern of aboveground biomass(AGB)and correlations of AGB to its environment in the Eurasian steppe by meta-analysis. AGB data used in this study were derived from the harvesting method and were obtained from three data sources(literatureglobal NPP database at the Oak Ridge National Laboratory Distributed Active Archive Center(ORNL)some data provided by other researchers). Our results demonstrated that:(1) as for the Eurasian steppe overallthe spatial variation in AGB exhibited significant horizontal and vertical zonality. In detailAGB showed an inverted parabola curve with the latitude and with the elevationwhile a parabola curve with the longitude. In additionthe spatial pattern of AGB had marked horizontal zonality in the Black Sea-Kazakhstan steppe subregion and the Mongolian Plateau steppe subregionwhile horizontal and vertical zonality in the Tibetan Plateau alpine steppe subregion.(2) Of the examined environmental variablesthe spatial variation of AGB was related to mean annual precipitation(MAP)mean annual temperature(MAT)mean annual solar radiation(MAR)soil Gravel contentsoil p H and soil organic content(SOC) at the depth of 0–30 cm. NeverthelessMAP dominated spatial patterns of AGB in the Eurasian steppe and its three subregions.(3) A Gaussian function was found between AGB and MAP in the Eurasian steppe overallwhich was primarily determined by unique patterns of grasslands and environment in the Tibetan Plateau. AGB was significantly positively related to MAP in the Black Sea-Kazakhstan steppe subregion(elevation < 3000 m)the Mongolian Plateau steppe subregion(elevation < 3000 m) and the surface(elevation ≥ 4800 m) of the Tibetan Plateau. Neverthelessthe spatial variation in AGB exhibited a Gaussian function curve with the increasing MAP in the east and southeast margins(elevation < 4800 m) of the Tibetan Plateau. This study provided more knowledge of spatial patterns of AGB and their environmental controls in grasslands than previous studies only conducted in local regions like the Inner Mongolian temperate grasslandthe Tibetan Plateau alpine grasslandetc.JIAO Cuicui YU Guirui HE Nianpeng MA Anna GE Jianping HU Zhongmin 2017Journal of Geographical Sciences2017,27,1:7
7Influence of heme oxygenase-1 gene transfer on the viability and function of rat islets in in vitro culture显示文摘AIM: To investigate the influence of heme oxygenase-1 (HO-1) gene transfer on the viability and function of cultured rat islets in vitro. METHODS: Islets were isolated from the pancreata of Sprague-Dawley rats by intraductal collagenase diges- tion, and purified by discontinuous Ficoll density gradient centrifugation. Purified rat islets were transfected with adenoviral vectors containing human HO-1 gene (Ad- HO-1) or enhanced green fluorescent protein gene (Ad- EGFP), and then cultured for seven days. Transfection was confirmed by fluorescence microscopy and Western blot. Islet viability was evaluated by acridine orange/ propidium iodide fluorescent staining. Glucose-stimulated insulin release was detected using insulin radioimmuno- assay kits and was used to assess the function of islets. Stimulation index (SI) was calculated by dividing the insulin release upon high glucose stimulation by the insulin release upon low glucose stimulation. RESULTS: After seven days culture, the viability of cultured rat islets decreased significantly (92% ± 6% vs 52% ± 13%, P < 0.05), and glucose-stimulated insulin release also decreased significantly (6.47 ± 0.55 mIU/ L/30IEQ vs 4.57 ± 0.40 mIU/L/30IEQ, 14.93 ± 1.17 mIU/L/30IEQ vs 9.63 ± 0.71 mIU/L/30IEQ, P < 0.05). Transfection of rat islets with adenoviral vectors at an MOI of 20 was efficient, and did not impair islet function. At 7 d post-transfection, the viability of Ad-HO-1 transfected islets was higher than that of control islets(71% ± 15% vs 52% ± 13%, P < 0.05). There was no significant difference in insulin release upon low glucose stimulation (2.8 mmol/L) among Ad-HO-1 transfected group, Ad-EGFP transfected group, and control group (P > 0.05), while when stimulated by high glucose (16.7 mmol/L) solution, insulin release in Ad-HO-1 transfected group was significantly higher than that in Ad-EGFP transfected group and control group, respectively (12.50 ± 2.17 mIU/L/30IEQ vs 8.87 ± 0.65 mIU/L/30IEQ; 12.50 ± 2.17 mIU/L/30IEQ vs 9.63 ± 0.71 mIU/L/30IEQ, P < 0.05). The SI of Ad-HO-1 transfected group was also significantly higher than that of Ad-EGFP transfected group and control group, respectively (2.21 ± 0.02 vs 2.08 ± 0.05; 2.21 ± 0.02 vs 2.11 ± 0.03, P < 0.05). CONCLUSION: The viability and function of rat islets decrease over time in in vitro culture, and heme oxygenase-1 gene transfer could improve the viability and function of cultured rat islets.Xiao-Bo Chen Yong-Xiang Li Yang Jiao Wei-Ping Dong Ge Li Jing Chen Jian-Ming Tan 2007World Journal of Gastroenterology2007,13,7:6
8Dynamic model for sucking process of pneumatic cutting-type safflower harvest device显示文摘This study proposed a method using negative pressure sucking the petals adhered around cones.The structural parameters of the sucking device affect the flow-field distribution in the negative-pressure air chamber.In order to improve the harvesting efficiency and quality of the pneumatic cutting-type safflower harvest device,a dynamic model was established and the safflower petals upwind area were measured.According to the test,the size parameters of the thornless Yumin safflower were as follows:the average necking diameter was 6.30 mm,the average capitulum diameter was 20.89 mm and the average petal length was 22.39 mm.The measured maximum frontal area of the safflower petal was 11-40 mm2.Secondly,the required negative pressure power that resulted in the rise of safflower petals was calculated.In general,when the suction of the negative pressure reaches 9.8 m/s,the safflower petals can be sucked successfully.The simulation of the flow field in the suction mouth indicated that the streamlined suction mouth was beneficial in reducing resistance and the test results of high-speed photography showed that the aforementioned condition could improve the efficiency of the upright safflower.And the test verified that the rate of the unshaped petals in the cylindrical air tunnel was low and the efficiency of carding and shaping under negative pressure was considerably better in wet petals than in dry ones.Results of the upright safflower petal experiment were consistent with the theoretical analysis and simulation conclusion,and indicated the precision of the dynamic model and suction flower mouth orifice-shaped simulation analysis.Ge Yun Zhang Lixin Qian Ying Jiao Xiaopan Chen Yuanbo 2016International Journal of Agricultural and Biological Engineering2016,9,5:6
9Aircraft-on-ground path following control by dynamical adaptive backstepping显示文摘The necessity of improving the air traffic and reducing the aviation emissions drives to investigate automatic steering for aircraft to effectively roll on the ground. This paper addresses the path following control problem of aircraft-on-ground and focuses on the task that the aircraft is required to follow the desired path on the runway by nose wheel automatic steering. The proposed approach is based on dynamical adaptive backstepping so that the system model does not have to be transformed into a canonical triangular form which is necessary in conventional backstepping design. This adaptive controller performs well despite the lack of information on the aerodynamic load and the tire cornering stiffness parameters. Simulation results clearly demonstrate the advantages and effectiveness of the proposed approach.Chen Bihua Jiao Zongxia Shuzhi Sam Ge 2013Chinese Journal of Aeronautics2013,26,3:5
10Processing,Quality,Safety,and Acceptance of Meat Analogue Products显示文摘Rapid global population growth has caused an increasing need for products containing protein.Meat products are the most common high-protein food source,but impact the environment,cause animal welfare issues,and raise public health concerns.Consumer health and food safety are paramount to the food industry.Both the scientists and food industry are actively seeking plant proteins to substitute for animal-sourced proteins.Plant proteins have a well-balanced amino acid composition,and exhibit great potential for replacing meat via the development of healthy,high-protein,low-saturated fat,cholesterol-free,and nutritionally similar meat-like products.Generally,meat analogue formulations are specially designed and processing conditions are optimized to obtain the texture and bite of real animal meat.This article focuses on plant-based meat analogues,and covers aspects regarding processing,products,quality,and nutritional and structural modifications.Product safety consciousness and consumer acceptance are also discussed.Challenges and perspectives for future research concerning nonmeat products are presented.Cuixia Sun Jiao Ge Jun He Renyou Gan Yapeng Fang 2021Engineering2021,7,5:4
11Experimental Study on Turbulent Structure of Humid Air Flame in a Bluff-body Burner显示文摘The main objective of the present experimental study is to analyze the turbulent structure in humid airnon-premixed flame, and determine the effect of humidity on the flow field and the flame stability limit in turbulentnon-premixed flame. Particle Image Velocimetry (PIV) is used to capture the instantaneous appearance ofvortex structures and obtain the quantitative velocity field. The distributions of Reynolds shear stress, mean androot-mean squared fluctuating (rms) velocities are examined to get insight into the effect of fuel-to-air velocity ratioon velocity flow field. The results show that with steam addition, the air-driven vortex in the bluff-body wakeis thinner; the biggest peaks of rms velocity and Reynolds shear stress are lower; the distance between the peaksof rms velocity on the sides of centerline reduces. Besides these, the flame stability is affected. Both central fuelpenetration limit and partially quenching limit reduce with steam addition.Bing Ge Shu-Sheng Zang Pei-qing Guo School of Mechanical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China 800, Dong Chuan Road, Shanghai, China. Zip: 200240 2009Journal of Thermal Science2009,18,2:4
12FOULING DETECTION IN FOOD VESSELS USING INTERDIGITAL LAMB WAVE TRANSDUCER显示文摘Lamb waves are used to detect fouling in food vessels. The propagation of the Lamb waves in plates exhibits many modes and dispersion characteristics, which have great influence on fouling detection. The relative distribution of the in-plane and out-of-plane displacement of the mode across the thickness of the plate will determine the sensitivity of the mode to a particular loading condition. By considering the dispersion and multi-mode characteristics of guided waves, an interdigital polyvinylidene fluoride (PVDF) transducer is designed to realize the mode selection of guided waves, and a single a0 mode is used for guided wave detection. Fouling detection experiments are conducted in the laboratory using epoxy adhesive on a thin plate. Using the interdigital PVDF transducer, three fouled areas are detected. Using one of the time-frequency analysis methods, the waveforms are further processed. This also demonstrates the validity of this method of fouling detection.JIAO Jingpin GE Haiyan WU Bin HE Cunfu 2007Chinese Journal of Mechanical Engineering2007,20,1:4
13The Shenzhen Declaration on Plant Sciences Uniting plant sciences and society to build a green, sustainable Earth显示文摘Peter R. Crane Song Ge De-Yuan Hong Hong-Wen Huang Gen-Lin Jiao Sandra Knapp W. John Kress Harold Mooney Peter H. Raven Jun Wen Wei-Hua Wu Huan-Ming Yang Wei-Hua Zhu Yu-Xian Zhu 2017Journal of Systematics and Evolution2017,55,5:3
14A versatile photodetector assisted by photovoltaic and bolometric effects显示文摘The advent of low-dimensional materials with peculiar structure and superb band properties provides a new canonical form for the development of photodetectors.However,the limited exploitation of basic properties makes it difficult for devices to stand out.Here,we demonstrate a hybrid heterostructure with ultrathin vanadium dioxide film and molybdenum ditelluride nanoflake.Vanadium dioxide is a classical semiconductor with a narrow bandgap,a high temperature coefficient of resistance,and phase transformation.Molybdenum ditelluride,a typical two-dimensional material,is often used to construct optoelectronic devices.The heterostructure can realize three different functional modes:(i)the p-n junction exhibits ultrasensitive detection(450 nm-2μm)with a dark current down to 0.2 pA and a response time of 17μs,(ii)the Schottky junction works stably under extreme conditions such as a high temperature of 400 K,and(iii)the bolometer shows ultrabroad spectrum detection exceeding 10μm.The flexible switching between the three modes makes the heterostructure a potential candidate for next-generation photodetectors from visible to longwave infrared radiation(LWIR).This type of photodetector combines versatile detection modes,shedding light on the hybrid application of novel and traditional materials,and is a prototype of advanced optoelectronic devices.Wei Jiang Tan Zheng Binmin Wu Hanxue Jiao Xudong Wang Yan Chen Xiaoyu Zhang Meng Peng Hailu Wang Tie Lin Hong Shen Jun Ge Weida Hu Xiaofeng Xu Xiangjian Meng Junhao Chu Jianlu Wang 2020Light(Science & Applications)2020,9,1:3
15Estimation of Aqueous Solubility (-lgS_w) of All Polychlorinated Biphenyl (PCB) Congeners by Density Functional Theory and Position of Cl Substitution (NPCS) Method显示文摘Optimization calculations of 209 polychlorinated biphenyls (PCBs) were carried out at the B3LYP/6-31G* level. It was found that there is significant correlation between the Cl substitution position and some structural parameters. Consequently, Cl substitution positions were taken as theoretical descriptors to establish a novel QSPR model for predicting –lgS_w of all PCB congeners. The model achieved in this work contains four variables, of which r2 = 0.9527, q2 = 0.9490 and SD = 0.25 with large t values. In addition, the variation inflation factors (VIFs) of variables in this model are all less than 5.0, suggesting high accuracy of the –lgS_w predicting model. And the results of cross-validation test and method validation also show that the model exhibits optimum stability and better predictive capability than that from the AM1 method.WEI Xiao-Yan GE Zhi-Gang WANG Zun-Yao XU Jiao 2007Chinese Journal of Structural Chemistry2007,26,5:3
16Development of catalytic combustion and CO_(2)capture and conversion technology显示文摘Changes are needed to improve the efficiency and lower the CO_(2)emissions of traditional coal-fired power generation,which is the main source of global CO_(2)emissions.The integrated gasification fuel cell(IGFC)process,which combines coal gasification and high-temperature fuel cells,was proposed in 2017 to improve the efficiency of coal-based power generation and reduce CO_(2)emissions.Supported by the National Key R&D Program of China,the IGFC for nearzero CO_(2)emissions program was enacted with the goal of achieving near-zero CO_(2)emissions based on(1)catalytic combustion of the flue gas from solid oxide fuel cell(SOFC)stacks and(2)CO_(2)conversion using solid oxide electrolysis cells(SOECs).In this work,we investigated a kW-level catalytic combustion burner and SOEC stack,evaluated the electrochemical performance of the SOEC stack in H2O electrolysis and H2O/CO_(2)co-electrolysis,and established a multiscale and multi-physical coupling simulation model of SOFCs and SOECs.The process developed in this work paves the way for the demonstration and deployment of IGFC technology in the future.Zhibin Yang Ze Lei Ben Ge Xingyu Xiong Yiqian Jin Kui Jiao Fanglin Chen Suping Peng 2021International Journal of Coal Science & Technology2021,8,3:3
17Efficacy of hybrid minimally invasive esophagectomy vs open esophagectomy for esophageal cancer: A meta-analysis显示文摘BACKGROUND The first line treatment regimen for esophageal cancer is still surgical resection and the choice of surgical scheme depends on surgeon.Now the efficacy comparison of hybrid minimally invasive esophagectomy(HMIE)and open esophagectomy(OE)is still controversial.AIM To compare the perioperative and postoperative outcomes of HMIE and OE in patients with esophageal cancer.METHODS PubMed,EMBASE,and Cochrane Library databases were searched for related articles.The odds ratio(OR)or standard mean difference(SMD)with a 95%confidence interval(CI)was used to evaluate the effectiveness of HMIE and OE.RESULTS Seventeen studies including a total of 2397 patients were selected.HMIE was significantly associated with less blood loss(SMD=-0.43,95%CI:-0.66,-0.20;P=0.0002)and lower incidence of pulmonary complications(OR=0.72,95%CI:0.57,0.90;P=0.004).No significant differences were seen in the lymph node yield(SMD=0.11,95%CI:-0.08,0.30;P=0.26),operation time(SMD=0.24,95%CI:-0.14,0.61;P=0.22),total complications rate(OR=0.68,95%CI:0.46,0.99;P=0.05),cardiac complication rate(OR=0.91,95%CI:0.62,1.34;P=0.64),anastomotic leak rate(OR=0.95,95%CI:0.67,1.35;P=0.78),duration of intensive care unit stay(SMD=-0.01,95%CI:-0.21,0.19;P=0.93),duration of hospital stay(SMD=-0.13,95%CI:-0.28,0.01;P=0.08),and total mortality rates(OR=0.70,95%CI:0.47,1.06;P=0.09)between the two treatment groups.CONCLUSION Compared with the OE,HMIE shows less blood loss and pulmonary complications.However,further studies are necessary to evaluate the long-term oncologic outcomes of HMIE.Jiao Yang Ling Chen Ke Ge Jian-Le Yang 2019World Journal of Gastrointestinal Oncology2019,11,11:3
18Chartrenoline, a novel alkaloid isolated from a marine Streptomyces chartreusis NA02069显示文摘A novel alkaloid, chartrenoline(1), featuring an unusual 6/6/5/5-tetracyclic nucleus, was isolated from a marine Streptomyces chartreusis NA02069. The structure of 1 including its absolute configurations was established by extensive analyses of its high resolution mass, NMR and single-crystal X-ray diffraction data. A plausible biosynthetic pathway for chartrenoline(1) is proposed.Chengli Liu Chenglong Yang Yingjie Zeng Jing Shi Lingyu Li Wei Li Ruihua Jiao Renxiang Tan Huiming Ge 2019Chinese Chemical Letters2019,30,1:3
19Formation of adiabatic shear band and deformation mechanisms during warm compression of Ti–6Al–4V alloy显示文摘Adiabatic shear band(ASB) was narrow region where softening occurred and concentrated plastic deformation took place. In present study, the effects of height reduction and deformation temperature on ASB were investigated by means of optical microscopy(OM) and scanning electron microscopy(SEM). And the deformation mechanisms within the shear band were discussed thoroughly with the help of transmission electron microscopy(TEM). There is a critical strain for the formation of ASB during warm compression of Ti–6Al–4V alloy. The width of ASB increases with height reduction increasing. Elongated alpha grains within shear band grow up with deformation temperature increasing. Some ultrafine grains that confirm the occurrence of dynamic recrystallization are observed within shear band during warm compression of Ti–6Al–4V alloy.Jiao Luo Lin-Feng Wang Miao-Quan Li Chang-Jian Ge Xiao-Xiao Ma Yong-Ting Yang 2016Rare Metals2016,35,8:3
20A NEW TECHNIQUE—ELECTROMAGNETIC CENTRIFUGAL CASTING PROCESS显示文摘A new technique of centrifugal casting under electromagnetic field was firstly proposedand investigated.Taking a heat resisting alloy steel 25Cr20Ni and an Al-Cu alloyas examples,products,though their length,diameter and wall thickness are varied,re-vealed so superior macrostructures that the mechanical properties are much improved incomparison with conventional centrifugal casting.GE Yunlong YANG Yuansheng JIAO Yuning HU Zhuangqi Institute of Metal Research,Academia Sinica,Shenyang,ChinaGAO Yunyan JIA Guanglin Northeast University of Technology,Shenyang,China associate professor,Institute of Low Energy Nuclear Physics,Beijing Normal University,Beijing,100875,China 1993Acta Metallurgica Sinica(English Letters)1993,6,11:2
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