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| 1 | Elevated basal intestinal mucosal cytokine levels in asymptomatic first-degree relatives of patients with Crohn's disease显示文摘AIM To determine levels of cytokines incolonic mucosa of asymptomatic first degreerelatives of Crohn’s disease patients.METHODS Cytokines(Interleukin(IL)1-Beta,IL-2,IL-5 and IL-8)were measured using ELISAin biopsy samples of normal looking colonicmucosa of first degree relatives of Crohn’sdisease patients(n = 9)and from normalcontrols(n = 10)with no family history ofCrohn’s disease.RESULTS Asymptomatic first degree relativesof patients with Crohn’s disease had significantlyhigher levels of basal intestinal mucosalcytokines(IL-2,IL-5 and IL-8)than normalcontrols.Whether these increased cytokinelevels serve as phenotypic markers for a geneticpredisposition to developing Crohns diseaselater on,or whether they indicate early(pre-clinical)damage has yet to be further defined.CONCLUSION Asymptomatic first degreerelatives of Crohn’s disease patients have higherlevels of cytokines in their normal-lookingintestinal mucosa compared to normal controls,This supports the hypothesis that increasedcytokines may be a cause or an early event inthe inflammatory cascade of Crohns disease andare not merely a result of the inflammatoryprocess. | Indaram AVK Nandi S Weissman S Lam S Bailey B Blumstein M Greenberg R Bank S | 2000 | World Journal of Gastroenterology2000，6，1： | 8 |
| 2 | 金刚石中的冰-Ⅶ相包裹体:来自地球深部地幔的含水流体证据显示文摘水在地球内部不同圈层的存在形态、分布、含量以及全球水循环一直以来都是固体地球科学研究的前沿热点问题之一。冰-Ⅶ相作为水的一种高压相,目前已经被国际矿物学会认定为一种新矿物。 | Tschauner O Huang S Greenberg E Prakapenka V B Rossman G R Shen A H Zhang D Newville M Lanzirotti A Tait K 张宝华 | 2018 | 矿物岩石地球化学通报2018，37，6： | 4 |
| 3 | Accuracy of biometric formulae for intraocular lens power calculation in a teaching hospital显示文摘AIM: To evaluate the accuracy of three commonly used biometric formulae across different axial lengths(ALs) at one United States Veterans Affairs teaching hospital.METHODS: A retrospective chart review was conducted from November 2013 to May 2018. One eye of each patient who underwent cataract surgery with a monofocal intraocular lens(IOL) was included. The range of postoperative follow-up period was from 3 wk to 4 mo. The Holladay 2, Barrett Universal II, and Hill-Radial Basis Function(Hill-RBF) formulae were used to predict the postoperative refraction for all cataract surgeries. For each formula, we calculated the prediction errors [including mean absolute prediction error(MAE)] and the percentage of eyes within ±0.25 diopter(D) and ±0.5 D of predicted refraction. We performed subgroup analyses for short(AL<22.0 mm), medium(AL 22.0-25.0 mm), and long eyes(AL>25.0 mm).RESULTS: A total of 1131 patients were screened, and 909 met the inclusion criteria. Resident ophthalmologists were the primary surgeons in 710(78.1%) cases. We found no statistically significant difference in predictive accuracy among the three formulae over the entire AL range or in the short, medium, and long eye subgroups. Across the entire AL range, the Hill-RBF formula resulted in the lowest MAE(0.384 D) and the highest percentage of eyes with postoperative refraction within ±0.25 D(42.7%) and ±0.5 D(75.5%) of predicted. All three formulae had the highest MAEs(>0.5 D) and lowest percentage within ±0.5 D of predicted refraction(<55%) in short eyes.CONCLUSION: In cataract surgery patients at our teaching hospital, three commonly used biometric formulae demonstrate similar refractive accuracy across all ALs. Short eyes pose the greatest challenge to predicting postoperative refractive error. | Kevin S Tang Elaine M Tran Allison J Chen David R Rivera Jorge J Rivera Paul B Greenberg | 2020 | International Journal of Ophthalmology(English edition)2020，13，1： | 3 |
| 4 | 14-day triple, 5-day concomitant, and 10-day sequential therapies for Helicobacter pylori infection in seven Latin American sites: a randomised trial显示文摘 | E Robert Greenberg Garnet L Anderson Douglas R Morgan Javier Torres William D Chey Luis Eduardo Bravo Ricardo L Dominguez Catterina Ferreccio Rolando Herrero Eduardo C Lazcano-Ponce María Mercedes Meza-Montenegro Rodolfo Pe?a Edgar M Pe?a Eduardo Salazar- | 2011 | The Lancet2011，，9790： | 2 |
| 5 | Habitability of Europa's crust:The role of tidal-tectonic processes显示文摘 | Greenberg R Geissler P Tufts B R | 2000 | Journal of Geophysics Research2000，105，17： | 1 |
| 6 | Transcription-dependent and-independent control of neuronal survival by the PI3K-Akt signaling pathway显示文摘 | Brunet A Datta S R Greenberg M E | 2001 | Curr Opin Neurobiol2001，11，3： | 1 |
| 7 | Hypernatrem hospital- ized patients显示文摘 | Palevsrnky PM Bhagrath R Greenberg A | 1996 | Ann Int Med1996，124，2： | 1 |
| 8 | Cytoreductive surgeryand intraperitoneal hyperthermic chemotherapy in peritoneal car-cinomatosis显示文摘 | Nesher E Greenberg R Avital S | 2007 | Isr Med Assoc J2007，9，11： | 1 |
| 9 | Pervaporation of trace chlorinated organics from water through irradiated polyethylene membrane 显示文摘 | Lee G T Krovvidi K R Greenberg D B | 1989 | J Membrane Sci1989，47，： | 1 |
| 10 | Real-time measurement of inorganic fouling of RO desalination membranes using ultrasonic time-domain reflectometry 显示文摘 | Mairal A P Greenberg A R | 1999 | Journal of Membrane Science1999，159，： | 1 |
| 11 | Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAX-AHF): a randomised, placebo-controlled trial显示文摘 | John R Teerlink Gad Cotter Beth A Davison G Michael Felker Gerasimos Filippatos Barry H Greenberg Piotr Ponikowski Elaine Unemori Adriaan A Voors Kirkwood F Adams Maria I Dorobantu Liliana R Grinfeld Guillaume Jondeau Alon Marmor Josep Masip Peter S Pang | 2013 | The Lancet . 2013 (9860)2013，，9860： | 1 |
| 12 | 388 EKB-569: a new irreversible inhibitor of epidermal growth factor receptor tyrsine kinase for the treatment of cancer显示文摘 | Discafani C Wang YF Tsou HR Overbeek EG Nilakantan R | 2000 | Clin Cancer Res2000，，： | 1 |
| 13 | Alert for perioperative visual loss:an unusual presentation of an orbital haemangioma during spinal surgery显示文摘 | Greenberg R Tymms A | 2003 | Anaesth Intensive Care2003，31，6： | 1 |
| 14 | Management of breast fibroadenomas显示文摘 | Greenberg R Skomiek Y Kaplan O | 1998 | J Gen Intem Med1998，13，9： | 1 |
| 15 | Diagnostic accuracy of CT angiography and CT perfusion for cerebral vasospasm:a meta-analysis显示文摘 | Greenberg ED Gold R Reichman M | 2010 | AJNR Am J Neuroradiol2010，31，： | 1 |
| 16 | Pregnancy outcome of women exposed to azathioprine during pregnancy显示文摘 | Goldstein LH Dolinsky G Greenberg R | 2007 | Birth Defects Res A Clin Mol Teratol2007，79，： | 1 |
| 17 | Vasopressin for refractory hypotension in extremely low birth weight neonates显示文摘 | Bidegain M Greenberg R Simmons C | | 0，，03： | 1 |
| 18 | The effect of WS2 nanoparticles on friction reduction in various lubrication regimes显示文摘 | Greenberg R Halperin G Etsion I | 2004 | Tribology Letters2004，17，2： | 1 |
| 19 | The endovascttlar management of visceral artery aneurysms and pseudoaneurysms显示文摘 | Tulsyan N Kashyap V Greenberg R | 2007 | J Vase Surg2007，45，： | 1 |
| 20 | Posaconazole as salvage therapy for zygomycosis 显示文摘 | GREENBERG R MULLANE K VAN BURIK J-A | 2006 | Antimicrob Ag Chemother2006，50，1： | 1 |
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