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| 1 | Cotton GhBAK1 Mediates Verticillium Wilt Resistance and Cell Death显示文摘导致病毒的基因 silencing (VIGS ) 由将他们的表示击倒为单个基因的功能的分析提供一条强大的途径。我们采用了这条途径把在对 Verticillium 抵抗的棉花的基因功能枯萎,世界范围的大多数破坏疾病之一。我们这里证明高度有效的 VIGS 在与部分抵抗引起线(CA4002 ) 到 Verticillium 的一朵棉花被获得枯萎,并且 GhMKK2 和 GhVe1 为它的抵抗被要求到 Verticillium 枯萎。Arabidopsis AtBAK1/SERK3,在工厂疾病抵抗的一个中央管理者,与五个成员,一起属于体的 embryogenesis 受体 kinases (SERK ) 的一个亚科 AtSERK1 到 AtSERK5。二 BAK1 orthologs 和一 SERK1 ortholog 在棉花染色体被识别。重要地, GhBAK1 为 CA4002 抵抗被要求到 Verticillium 枯萎。令人惊讶地, GhBAK1 的 silencing 是足够的触发在棉花伴有反应的氧种类的生产的房间死亡。这结果从 AtBAK1 和 AtSERK4 在房间死亡控制在玩冗余的函数的 Arabidopsis 是不同的。显然,而 AtSERK4/5 是在 Arabidopsis 的最新发展的基因,棉花仅仅发展了 SERK1 和 BAK1。我们的研究在 Verticillium 显示 BAK1 的功能的重要性枯萎抵抗并且在不同植物种类建议 SERK 家庭成员的动态进化。 | Xiquan Gao Fangjun Li Maoying Li Ali S.Kianinejad Jane K.Dever Terry A.Wheeler Zhaohu Li Ping He Libo Shan | 2013 | Journal of Integrative Plant Biology2013，55，7： | 13 |
| 2 | Electrochemical performance of Ti_(3)C_(2)supercapacitors in KOH electrolyte显示文摘Two-dimensional(2D)carbide Ti_(3)C_(2)was synthesized by exfoliating Ti_(3)AlC_(2)in HF solution and used for supercapacitive performance investigation in 3 M KOH electrolyte.The specific surface area(SSA)of as-synthesized Ti_(3)C_(2)was 22.35 m^(2)/g.Ti_(3)C_(2)-based supercapacitor electrodes exhibited good energy storage ability and had a volumetric capacitance 119.8 F/cm^(3)at the current density of 2.5 A/g.Moreover,the addition of carbon black into Ti_(3)C_(2)powders greatly improved the performance of Ti_(3)C_(2)-based capacitors because carbon black restrained the preferred orientation of 2D Ti_(3)C_(2),providing fast ion transport channels,and in turn,decreasing electrical resistance from 16.7Ωto 3.5Ω. | Yupeng GAO Libo WANG Zhengyang LI Yafei ZHANG Baolin XING Chuanxiang ZHANG Aiguo ZHOU | 2015 | Journal of Advanced Ceramics2015，4，2： | 10 |
| 3 | Efficient Synthesis of Graphene Nanoribbons Sonochemically Cut from Graphene Sheets显示文摘We report a facile approach to synthesize narrow and long graphene nanoribbons (GNRs) by sonochemically cutting chemically derived graphene sheets (GSs). The yield of GNRs can reach ~5 wt% of the starting GSs. The resulting GNRs are several micrometers in length, with ~75% being single-layer, and ~40% being narrower than 20 nm in width. A chemical tailoring mechanism involving oxygen-unzipping of GSs under sonochemical conditions is proposed on the basis of experimental observations and previously reported theoretical calculations;it is suggested that the formation and distribution of line faults on graphite oxide and GSs play crucial roles in the formation of GNRs. These results open up the possibilities of the large-scale synthesis and various technological applications of GNRs. | Zhong-Shuai Wu Wencai Ren Libo Gao Bilu Liu Jinping Zhao Hui-Ming Cheng | 2010 | Nano Research2010，3，1： | 10 |
| 4 | Diallyl trisulfide induces apoptosis and inhibits proliferation of A549 cells in vitro and in vivo显示文摘肺癌症是在整个世界的癌症相关的死亡的领先的原因。在最近的年里,肺的腺癌在频率超过了有鳞的房间癌并且是在许多国家的肺癌症的占优势的形式。流行病学的调查显示出在消费和死亡从许多癌症评估的大蒜(瞀或蒜之类 sativum ) 之间的一种反的关系。Diallyl trisulfide (DATS ) 是导出大蒜的混合物之一(是也知道:organosulfer 混合物,振荡) 。DATS 能导致 apoptosis 并且禁止许多癌症细胞线的生长。我们的学习证明 DATS 导致的 apoptotic 事件是通过导致了 Bax/Bcl-2 和 caspase-3, -8, 和 -9 的活动的比率的起来规定的 anti-apoptotic Bcl-2 的重要减少的线粒体依赖者 caspase 串联。最后, DATS 导致了 apoptosis 并且在一个集中依赖者和时间依赖者举止禁止了增长。由与 A549 异种皮移植建立女 BALB/c 裸体老鼠的一个动物模特儿,没有与控制组相比引起重量损失或任何另外的副作用,而且,我们在裸体老鼠发现 DATS 的那口头的 gavage A549 异种皮移植的显著地延迟的生长。在 vitro 并且在 vivo 的所有证据建议 DATS 能是理想的反癌症药。 | Wenjun Li Hui Tian Lin Li Shuhai Li Weiming Yue Zhitao Chen Lei Qi Wensi Hu Yingchao Zhu Bin Hao Cun Gao Libo Si Fei Gao | 2012 | Acta Biochimica et Biophysica Sinica2012，44，7： | 6 |
| 5 | Flexible Waterproof Piezoresistive Pressure Sensors with Wide Linear Working Range Based on Conductive Fabrics显示文摘Developing flexible sensors with high working performance holds intense interest for diverse applications in leveraging the Internet-of-things(IoT)infrastructures.For flexible piezoresistive sensors,traditionally most efforts are focused on tailoring the sensing materials to enhance the contact resistance variation for improving the sensitivity and working range,and it,however,remains challenging to simultaneously achieve flexible sensor with a linear working range over a high-pressure region(>100 kPa)and keep a reliable sensitivity.Herein,we devised a laserengraved silver-coated fabric as'soft'sensor electrode material to markedly advance the flexible sensor's linear working range to a level of 800 kPa with a high sensitivity of 6.4 kPa^-1 yet a fast response time of only 4 ms as well as long-time durability,which was rarely reported before.The integrated sensor successfully routed the wireless signal of pulse rate to the portable smartphone,further demonstrating its potential as a reliable electronic.Along with the rationally building the electrode instead of merely focusing on sensing materials capable of significantly improving the sensor's performance,we expect that this design concept and sensor system could potentially pave the way for developing more advanced wearable electronics in the future. | Hongcheng Xu Libo Gao Yuejiao Wang Ke Cao Xinkang Hu Liang Wang Meng Mu Min Liu Haiyan Zhang Weidong Wang Yang Lu | 2020 | Nano-Micro Letters2020，12，11： | 4 |
| 6 | Clinical data analysis reveals the role of OGR1 (GPR68) in head and neck squamous cancer显示文摘Background:Head and neck squamous cancer(HNSC)frequently occurs in the clinic.Revealing the role of the genes that correlate with cancer cell outgrowth will contribute to potential treatment target identification and tumor inhibition.Methods:The gene expression profiles and gene ontology of the proton-sensing G-protein-coupled receptor OGR1 were analyzed using the TCGA(The Cancer Genome Atlas)database.The effects of sex,age,race,and degree of malignancy on HNSC were investigated,and the survival times of HNSC patients with high or low/medium expression levels of OGR1 were compared.Methylation of the OGR1 promoter CpG sites was also investigated and OGR1-related genes were analyzed using gene set enrichment analysis.Results:OGR1 is overexpressed in HNSC patients.However,compared with the low/median expression group,the high OGR1 expression group did not have different survival rates.The OGR1 expression level differed across sex,age,race,and degree of malignancy,while the methylation of the OGR1 promoter CpG sites was maintained at a similar level.Gene set enrichment analysis revealed that OGR1 was positively correlated with head and neck cancer,cisplatin resistance,hypoxia,angiogenesis,cell migration,and TGF-β.Conclusion:The expression of OGR1 correlated with HNSC progression and survival and thus can serve as a potential treatment target and prognostic marker. | Wenlong Zhang Yong Han Weisha Li Lin Cao Libo Yan Chuan Qin Ran Gao | 2020 | Animal Models and Experimental Medicine2020，3，1： | 2 |
| 7 | Cotton Gh BAK 1 Mediates Verticillium Wilt Resistance and Cell Death显示文摘 | Xiquan Gao Fangjun Li Maoying Li Ali S. Kianinejad Jane K. Dever Terry A. Wheeler Zhaohu Li Ping He Libo Shan | 2013 | J Integr Plant Biol2013，，7： | 2 |
| 8 | miR-24-3p promotes colon cancer progression by targeting ING1显示文摘Dear Editor,Activation or upregulation of oncogenes and/or loss of function or downregulation of tumour suppressors are central to the processes involved in the transformation from normal colonic mucosa to malignant tumours.Inhibitor of growth 1(ING1)has been functionally linked to cell cycle arrest,apoptosis and chromatin remodelling. | Zhiying Gao Likun Zhou Shiyu Hua Huan Wu Laizhi Luo Libo Li Shuping Wang Yanqing Liu Zhen Zhou Xi Chen | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 2 |
| 9 | Down-regulation of MTA1 protein leads to the inhibition of migration, invasion, and angiogenesis of non-small-cell lung cancer cell line显示文摘联系转移的蛋白质 1 (MTA1 ) 高表示在许多人的好攻击的肿瘤被检测了并且在象侵略,转移,和 angiogenesis 那样的恶意的生物行为起重要作用。然而,在调整 non-small-cell 肺癌症(NSCLC ) 的恶意的行为的 MTA1 蛋白质的特定的角色和机制房间仍然保持不清楚。阐明 MTA1 蛋白质的详细函数,我们下面调整在由在 vitro 的 RNA 干扰(RNAi ) 的 NSCLC 房间线的 MTA1 蛋白质表达式,并且发现 MTA1 蛋白质的下面规定显著地禁止了 95D 房间的移植和侵略潜力。进一步的研究表明 MTA1 蛋白质的下面规定显著地减少了矩阵 metalloproteinase-9 的活动,它能是为 95D 房间移植和侵略的抑制负责的机制。另外,试管形成试金证明 MTA1-siRNA 95D 房间的调节媒介导致的完全的试管的数字比 95D 房间的显著地小。这些调查结果证明那 MTA1 蛋白质在调整 95D 房间的迁居,侵略,和 angiogenesis 潜力起重要作用,由 RNAi 建议那条 MTA1 蛋白质下面规定可能是一条新奇治疗学的途径禁止 NSCLC 的前进。 | Shuhai Li Hui Tian Weiming Yue Lin Li Cun Gao Libo Si Wenjun Li Wensi Hu Lei Qi Ming Lu | 2013 | Acta Biochimica et Biophysica Sinica2013，45，2： | 2 |
| 10 | Enhancing stability by tuning element ratio in 2D transition metal chalcogenides显示文摘Two-dimensional(2D)transition metal chalcogenides(TMCs)are known to be susceptible to the atmosphere,which greatly obscures the intrinsic physical and chemical properties.The quantitative origin of the instability on the atomic scale has not been well investigated due to the lack of environmentally stable TMCs sample.Here,we find the stability of the grown TMCs is strongly relevant to their initial element ratios,and thus the stoichiometric bonded TMCs have favorable stability,benefitted from the TMCs with controllable chalcogenisation.In this study,the degree of structural degradation has been quantitatively defined by the reduced element ratio of chalcogen to metal through the time-dependent characterizations,and the non-stoichiometric ratios in TMCs reveal the atomic lattices with point defects like additive bonds or vacancies inside.This study not only provides a potential view to fabricate environmentally stable TMCs based devices,but also will bring an effective feasibility of stacking stable vertical heterostructures. | Zhenjia Zhou Tao Xu Chenxi Zhang Shisheng Li Jie Xu Litao Sun Libo Gao | 2021 | Nano Research2021，14，6： | 2 |
| 11 | Stereolithographic 3D Printing-Based Hierarchically Cellular Lattices for High-Performance Quasi-Solid Supercapacitor显示文摘3D printing-based supercapacitors have been extensively explored,yet the rigid rheological requirement for corresponding ink preparation significantly limits the manufacturing of true 3D architecture in achieving superior energy storage.We proposed the stereolithographic technique to fabricate the metallic composite lattices with octet-truss arrangement by using electroless plating and engineering the 3D hierarchically porous graphene onto the scaffolds to build the hierarchically cellular lattices in quasi-solid supercapacitor application.The supercapacitor device that is composed of composite lattices span several pore size orders from nm to mm holds promising behavior on the areal capacitance(57.75 mF cm-2),rate capability(70% retention,2-40 mA cm-2),and long lifespan(96% after 5000 cycles),as well as superior energy density of 0.008 mWh cm-2,which are comparable to the state-of-the-art carbon-based supercapacitor.By synergistically combining this facile stereolithographic 3D printing technology with the hierarchically porous graphene architecture,we provide a novel route of manufacturing energy storage device as well as new insight into building other high-performance functional electronics. | Jianzhe Xue Libo Gao Xinkang Hu Ke Cao Wenzhao Zhou Weidong Wang Yang Lu | 2019 | Nano-Micro Letters2019，11，3： | 2 |
| 12 | Three-dimensional flexible and conductive interconnected graphene networks grown by chemical vapour deposition显示文摘 | CHEN Zongping PEN Wencai GAO Libo | 2011 | Nature Materials2011，10，6： | 1 |
| 13 | Synthesis of High-quality Graphene with a Pre-determined Number of Layers显示文摘 | Wu Zhongshuai Ren Wencai Gao Libo | 2009 | Carbon2009，47，： | 1 |
| 14 | Graphene hydrogels deposited in nickel foams for high-rate electrochemical capacitors显示文摘 | CHEN Jongping REN Weneai GAO Libo | 2012 | Advanced Materials2012，2403，： | 1 |
| 15 | Clinical features and risk factors for post-partum depression in a large cohort of Chinese women with recurrent major depressive disorder显示文摘 | Tian Tian Yihan Li Dong Xie Yifeng Shen Jianer Ren Wenyuan Wu Chengbin Guan Zhen Zhang Danning Zhang Chengge Gao Xiaoming Zhang Jinbo Wu Hong Deng Gang Wang Yunshu Zhang Yun Shao Han Rong Zhaoyu Gan Yan Sun Bin Hu Jiyang Pan Yi Li Shufan Sun Libo Song Xue | 2011 | Journal of Affective Disorders2011，，3： | 1 |
| 16 | Recent developments in asphalt-aggregate separation technology for reclaimed asphalt pavement显示文摘Reclaimed asphalt pavement(RAP)has significant recycling value because it contains nonrenewable resources including asphalt and aggregate.However,thus far,only a small part of RAP materials can be used in the con-struction of recycled asphalt pavement,and the usage is regarded as a low-value utilization in the underlying layers.One of the most important reasons for this shortcoming is the problem of false particle size and pseudo gradation of RAP materials.Therefore,identifying suitable asphalt-aggregate separation technology is essential for improving the utilization of RAP materials in recycled asphalt mixture and enhancing the construction quality of recycled asphalt pavement.To address this,the paper performed a systematic review of asphalt-aggregate separation technologies for processing RAP materials and their prospects.Firstly,based on the composition of the asphalt mixture and the characteristics of RAP materials after aging,the key RAP separation technologies were proposed.Then,the concept,principle,and implementation methods of physical,chemical,and biological sep-aration methods of RAP materials were comprehensively analyzed.Moreover,the advantages and disadvantages of various separation technologies were discussed by comparing them with the related technologies in the petrochemical industry.The application prospects of various asphalt-aggregate separation methods for RAP materials can provide a reference for upgrading and expanding solid waste recycling technology for asphalt pavement. | Decheng Feng Jiwei Cao Libo Gao Junyan Yi | 2022 | Journal of Road Engineering2022，2，4： | 1 |
| 17 | Repeatedgrowth and bubbling transfer of graphene withmillimetre-size single-crystal grains using platinum 显示文摘 | Libo Gao Wencai Ren Huilong Xu Li Jin | 2012 | Nature Communications2012，，3： | 1 |
| 18 | SMND-309, a novel derivative of salvianolic acid B, protects rat brains ischemia and reperfusion injury by targeting the JAK2/STAT3 pathway显示文摘 | Haibo Zhu Libo Zou Jingwei Tian Guangying Du Yubai Gao | 2013 | European Journal of Pharmacology (-)2013，，1： | 1 |
| 19 | Clinical and epidemiological characteristics of a fatal case of avian influenza A H10N8 virus infection: a descriptive study显示文摘 | HaiYing Chen Hui Yuan Rongbao Gao Jinxiang Zhang Dayan Wang Ying Xiong GuoYin Fan Fan Yang Xiaodan Li Jianfang Zhou Shumei Zou Lei Yang Tao Chen Libo Dong Hong Bo Xiang Zhao Ye Zhang Yu Lan Tian Bai Jie Dong Qun Li ShiWen Wang YanPing Zhang Hui Li Tian Go | 2014 | The Lancet2014，，： | 1 |
| 20 | Application and Development of Biosensors显示文摘As a new kind of analytical instrument,the principles,types and characters of biosensors were discussed in this paper.A biosensor is usually composed of a recognition element of biological origin and a physicochemical transducer.The biological element is capable of sensing the presence,activity or concentration of a chemical analyse in solution.The sensing takes place either as a binding event or a biocatalytical event.These interactions produce a measurable change in a solution property,in which the transducer is converted into a quantifiable electrical signal.The principles,types and applications of biosensors in environmental inspection,food production,clinical medicine and military defense were reviewed,and the trends in research were predicated.Furthermore,an attempt had been made to describe the future development directions and prospects. | GAO Yuelin LI Jichang HUO Guicheng LIU Libo | 2008 | Journal of Northeast Agricultural University(English Edition)2008，15，2： | 1 |
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