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| 1 | Characteristics of Twin Lamellar Structure in Magnesium Alloy during Room Temperature Dynamic Plastic Deformation显示文摘The microstructures of the as-rolled magnesium alloy subjected to dynamic plastic deformation along the rolling direction have been investigated.Mostly one {1012} twin variant or a twin variant pair is activated in a grain,leading to a parallel {1012} twin lamellar structure.At the stage of twinning-dominated deformation(ε<~8%),lamellar thickness decreases significantly with strain,from 5.55 to 2.49μm.The evolution of lamellar thickness during deformation is directly related to {1012} twin activity.When plastic strain is greater than ~8%,the twin lamellar structure disappears because the volume fraction of twins almost saturates at a value of ~90%. | Chao Lou Xiyan Zhang Gaolin Duan Jian Tu Qing Liu | 2014 | Journal of Materials Science & Technology2014，30，1： | 5 |
| 2 | Selective conversion of biomass-derived furfuryl alcohol into n-butyl levulinate over sulfonic acid functionalized TiO_(2) nanotubes显示文摘Sulfonic acid functionalized titanate nanotubes were prepared by the sulphonation reaction of hydrothermally synthesized TiO_(2) nanotubes(TNTs) using chlorosulfonic acid as the sulfating agent.The as-prepared catalysts were characterized by fourier transform infrared(FT-IR)spectroscopy,transmission electron microscopy(TEM),scanning electron microscopy-energy dispersive X-ray spectroscopy(SEM-EDX),Xray diffraction(XRD) analysis,thermogravimetry-differential thermal gravimetry(TG-DTG) and X-ray photoelectron spectroscopy(XPS)techniques.The characterization results revealed that the catalysts retained the tubular structure of the TNTs and possessed a large number of active sulfonic acid sites.The catalytic performance of the catalysts for the synthesis of n-butyl levulinate was investigated via the alcoholysis of biomass-derived furfuryl alcohol under atmospheric pressure.The effects of the reaction factors such as the catalyst dosage,reaction time,and temperature on the alcoholysis of the furfuryl alcohol were systematically studied.Under mild conditions,about 79.9% yield of n-butyl levulinate was achieved.In addition,the catalysts showed a stable catalytic performance after four consecutive cycles.Furthermore,no leaching of the active species was observed during the hot filtration testing,which can be attributed to the covalently linked –SO_(3)H groups on the TNTs surface.In addition,the opened tubular nanostructure of the catalyst and the introduced strong Br?nsted acid sites exhibited synergistic effects,which facilitated the selective conversion of the furfuryl alcohol to butyl levulinate. | Shuolin Zhou Jinhua Lai Xianxiang Liu Geng Huang Gaolin You Qiong Xu Dulin Yin | 2022 | Green Energy & Environment2022，7，2： | 3 |
| 3 | Extensively Drug-Resistant(XDR)Salmonella Typhi Outbreak by Waterborne Infection——Beijing Municipality,China,January-February 2022显示文摘Summary What is already known about this topic?Typhoid fever remains a major public health problem in developing countries.Waterborne typhoid fever affects an estimated 27 million people worldwide each year.Decades of indiscriminate antibiotic usage has driven the emergence and spread of multidrug-resistant(MDR)and even extensively drug-resistant(XDR)Salmonella Typhi(S.Typhi)strains. | Yu Wang Dan Lu Yingying Jin Huanxin Wang Bing Lyu Xin Zhang Ying Huang Gaolin Shu Baiwei Liu Changying Lin Hao Zhao Mingqiang Zhao Lingyu Shen Zhiyong Gao Daitao Zhang Quanyi Wang Mei Qu Lei Jia | 2022 | China CDC weekly2022，4，12： | 1 |
| 4 | Effects of artificial grassland establishment on soil nutrients and carbon properties in a black-soil-type degraded grassland显示文摘 | Gaolin Wu Zhenheng Liu Lei Zhang | 2010 | Plant Soil2010，333，： | 1 |
| 5 | The effect of laser scanning path on microstructures and mechanical properties of laser solid formed nickel-base superalloy Inconel 718显示文摘 | Fencheng Liu Xin Lin Chunping Huang Menghua Song Gaolin Yang Jing Chen Weidong Huang | 2010 | Journal of Alloys and Compounds2010，，： | 1 |
| 6 | Laser solid forming Zr-based bulk metallic glass显示文摘 | Gaolin Yang Xin Lin Fencheng Liu Qiao Hu Liang Ma Jinfu Li Weidong Huang | 2011 | Intermetallics2011，，： | 1 |
| 7 | Effect of fencingand grazing on a Kobresia-dominated meadow in the Qinghai- Tibetan Plateau 显示文摘 | WU Gaolin DU Guozhen LIU Zhenheng | 2009 | Plant and Soil2009，319，12： | 1 |
| 8 | Microstructure and residual stress of laser rapid formed Inconel 718 nickel-base superalloy显示文摘 | Fencheng Liu Xin Lin Gaolin Yang Menghua Song Jing Chen Weidong Huang | 2010 | Optics and Laser Technology2010，，： | 1 |
| 9 | Rho kinase mediates transforming growth factor-β1-induced vasculogenic mimicry formation: involvement of the epithelial-mesenchymal transition and cancer stemness activity显示文摘Vasculogenic mimicry(VM),a newly defined pattern of tumor blood supply,has been identified in several malignant tumors,including hepatocellular carcinoma(HCC).Rho kinase(ROCK)plays an important role in various types of cancers.However,whether ROCK participates in transforming growth factor-β1(TGF-β1)-induced VM formation is unclear.Here,we evaluated the role of ROCK in TGF-β1-induced VM formation in HCC.Our findings showed that the TGF-β1/ROCK signaling pathway is involved in VM formation by inducing the epithelial-mesenchymal transition.Furthermore,TGF-^1 and ROCK were found to play distinct roles in the cancer stem cell phenotype during VM formation.These results provide insights into potential antitumor therapies for inhibiting VM by targeting the TGF-pi/ROCK signaling pathway in HCC. | Xue Zhang Jigang Zhang Heming Zhou Gaolin Liu Qin Li | 2020 | Acta Biochimica et Biophysica Sinica2020，52，4： | 1 |
| 10 | Effects of artificial grassland establishment on soil nutrients and carbon properties in a black-soil-type degraded grassland显示文摘 | Wu Gaolin Liu Zhenheng Zhang Lei | 2010 | Plant and Soil2010，333，12： | 1 |
| 11 | Scheme of Optical Fiber Temperature Sensor Employing Deep-Grooved Process Optimization显示文摘优化采用深沟的过程的光纤维温度传感器,一个新奇计划被建议。由有希望的公司制作了<潜水艇class=“ a-plus-plus ”> 2 激光照耀系统与高精确基于二维的扫描机械化了舞台,新奇深沟的光纤维温度传感器与它传播变细的温度敏感被获得上层的马槽搬运了的 0.107 dB/of 从进中间和更低的对流层在的极的更低的平流层的充满臭氧的空气中间纬度,并且在那里增加了臭氧集中。在 COL 的成熟阶段期间,同温层的空气逆时针方向被搬运进对流层。向后的轨道模型被用来在它的妈柼 ? 柼期间在 COL 以内发现空气的来源区域集体吗?? | Yu LIU Cong LIU Gaolin XIANG Ruijie WANG Yibing WANG Lei Xiang Linzhi WU Song LIU | 2015 | Photonic Sensors2015，5，1： | 1 |
| 12 | Recrystallization and Its Influence on Microstructures and Mechanical Properties of Laser Solid Formed Nickel Base Superalloy Ineonel 718 显示文摘 | Liu Fencheng Lin Xin Yang Gaolin | 2011 | Rare Metals2011，30，1： | 1 |
| 13 | Microstructure and residual stress of laser rapid formed Inconel 718 nikel-base superalloy 显示文摘 | Liu Fencheng Lin Xin Gaolin Yang | 2011 | Optics & Laser Technology2011，43，： | 1 |
| 14 | Laser solid forming Zr-based bulk metallic glass显示文摘 | Gaolin Yang Xin Lin Fencheng Liu Qiao Hu Liang Ma Jinfu Li Weidong Huang | 2011 | Intermetallics2011，，： | 1 |
| 15 | Micro- structure and residual stress of laser rapid formed Inconel 718 nickel-base superalloy 显示文摘 | Liu Fencheng Lin Xin Yang Gaolin | 2011 | Optics & Laser Technology2011，43，： | 1 |
| 16 | 3D printed porous titanium filled with mineralized UV-responsive chitosan hydrogel promotes cell proliferation and osteogenesis in vitro显示文摘The modification of 3D printed porous titanium(Ti),especially for the internal pore structure,is critical and has received more attention to promoting its osteogenesis for clinical use.Ultra-violet(UV)responsive chitosan(CSMA),as an injectable filling material,was firstly incorporated into porous Ti,and then CSMA was in-situ mineralized by carbon oxide(CO_(2))diffusion(CSMA/CaCO_(3)).Their physical-chemical and biological properties were investigated in vitro.CaCO_(3) crystals within CSMA hydrogels were successfully deposited into pores of porous Ti,which exhibited favorable biocompatibility.Ti implants filled with CSMA/CaCO_(3) promoted adhesion and proliferation of bone mesenchymal stem cells(BMSCs).Moreover,Ti implant filled CSMA/CaCO_(3) hydrogels could increase alkaline phosphatase(ALP)activities,up-regulate osteopontin(OPN)and osteocalcin(OCN)expression levels,and enhance extracellular mineralization.3D printed porous Ti filled with mineralized UV-responsive chitosan hydrogel could promote proliferation and osteogenesis of BMSCs,and have great potential for the modification of porous Ti implants in bone tissue engineering. | Jiazhao Yang Fan Liu Changshun Zhou Hejie Li Gaolin Yang Shiyuan Fang In-Seop Lee Yi Liu Hao Bai Cen Chen | 2023 | Journal of Materials Science & Technology2023，，11： | 0 |
| 17 | In situ Activatable Peptide-based Nanoprobes for Tumor Imaging显示文摘Owing to its excellent biological properties,peptide has been widely used in the design of nanoprobes capable of enhancing tumor imaging signals.In recent years,a number of peptide-based nanoprobes with strong loading capacity and great biocompatibility have been developed for precision tumor imaging by coupling peptide motifs with different imaging agents.It is worth noting that,compared with“always on”mode,the use of stimulus-mediated in situ activatable mode to design and control the self-assembly or nanostructure transformation of peptide-based nanoprobes in vivo can achieve the significant improvement of imaging efficiency.Herein,we summarize the recent progress of in situ activatable peptide-based nanoprobes for tumor imaging in diverse imaging modes,including magnetic resonance imaging(MRI),fluorescence imaging(FI),photoacoustic imaging(PAI),radionuclide imaging(RI)and multimodal imaging.Finally,we briefly prospect the challenges and potential development directions of this field. | LIU Zhiyu LIANG Gaolin ZHAN Wenjun | 2021 | Chemical Research in Chinese Universities2021，37，4： | 0 |
| 18 | Enzymatic self-assembly/disassembly turns “ON”/“OFF” the mimetic hydrolytic activity of histidine nanofibers显示文摘Mimetic enzymes are devised as alternates or supplements of natural enzymes in broad fields but regulating their activities in a switchable manner remains challenging.Herein,we proposed an enzymatic self-assembly/disassembly strategy to address this issue.A peptide molecule Nap FFEYIH(YH) was rationally designed which,after self-assembling into nanofibers,lined up the histidine moieties to form active hydrolysis centers for mimicking hydrolase activity.Enzymatic dephosphorylation of Nap FFEYp IH(Yp H) by alkaline phosphatase to yield YH also turned “ON” the hydrolase activity.In turn,phosphorylation of YH by phosphokinase epidermal growth factor receptor to yield Yp H disassembled the nanofibers and thus turned the activity “OFF”.As such,the “ON”/“OFF” of the mimetic hydrolase activities could be regulated under physiological conditions through ALP/EGFR-mediated self-assembly/disassembly of histidine nanofibers.This work provides a feasible strategy for the on-demand fabrication of artificial enzymes with controllable and superior activities. | Xianbao Sun Manli Wang Xiaoyang Liu Wenjun Zhan Guangqiong Xu Qiaochu Jiang Hai-Dong Xu Fuqiang Wang Gaolin Liang | 2024 | Science China Chemistry2024，67，2： | 0 |
| 19 | Highly lipophilic coumarin fluorophore with excimer-monomer transition property for lipid droplet imaging显示文摘Lipid droplet(LD) fluorescent imaging plays an important role in the detection of lipid-related diseases.Due to their poor photostability and low hydrophobicity of currently available LD imaging fluorophores,LD imaging is limited by its short imaging period and low imaging contrast. Herein, we reasonably designed a highly lipophilic compound Cou-Flu with excellent photostability and excimer-monomer transition property. It exhibited weak excimer emission in cytoplasm, but strong monomer emission in LDs,enabling high contrast LD imaging and LD movement tracing in cells. Zebrafish imaging study demonstrated that Cou-Flu was also suitable for in vivo LD detection with excellent sensitivity. We anticipate that Cou-Flu could be widely applied to understand LD-related intracellular activities and even LD-related diseases in the future. | Xiang Shi Ge Gao Xiaoyang Liu Lingling Xu Yu Deng Rui Wang Gaolin Liang | 2023 | Chinese Chemical Letters2023，34，3： | 0 |
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