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| 1 | 针对患者利益的机器学习和人工智能研究:在透明性、可重复性、伦理和有效性等方面的20个关键问题显示文摘机器学习(ML)、人工智能(AI)和其他现代统计方法正为利用先前尚未开发且极速增长的数据资源提供新的机会,以期让患者获益。尽管目前正在进行许多有前景的研究,特别是在图像方面,但就文献整体而言还缺乏透明度、对可重复性清晰的阐述、对潜在伦理问题的探究,以及对有效性的明确验证。这些问题的存在有许多原因,其中最重要的一点(为此我们提供了初步解决方案)就是当前缺乏针对ML和AI的最佳实践指南。我们认为从事研究的跨学科团队和应用ML/AI影响健康的项目,将因解决有关透明度、可重复性、伦理和有效性(TREE)的一系列问题而受益。这里提出的20个关键问题为研究团队提供了一个研究设计、实施和报告框架;帮助编辑和同行评审专家评估文献的贡献;让患者、临床医生和政策制定者评估新发现可能会给患者带来的获益。 | Sebastian Vollmer Bilal A Mateen Gergo Bohner Franz J Kirdly Rayid Ghani Pall Jonsson Sarah Cumbers Adrian Jonas Katherine S L McAllister Puja Myles David Granger Mark Birse Richard Branson Karel G M Moons Gary S Collins John P A Chris Holmes Harry Hemingwayp 李峰(译) 徐磊(校) 赵邑(校) | 2020 | 英国医学杂志中文版2020，23，9： | 5 |
| 2 | Eosinophilic esophagitis: Updated consensus recommendations for children and adults显示文摘 | Chris A. Liacouras Glenn T. Furuta Ikuo Hirano Dan Atkins Stephen E. Attwood Peter A. Bonis A. Wesley Burks Mirna Chehade Margaret H. Collins Evan S. Dellon Ranjan Dohil Gary W. Falk Nirmala Gonsalves Sandeep K. Gupta David A. Katzka Alfredo J. Lucendo Jo | 2011 | The Journal of Allergy and Clinical Immunology2011，，1： | 3 |
| 3 | Nitinol Stent Implantation Versus Balloon Angioplasty for Lesions in the Superficial Femoral Artery and Proximal Popliteal Artery: Twelve-Month Results From the RESILIENT Randomized Trial显示文摘 | John R. Laird Barry T. Katzen Dierk Scheinert Johannes Lammer Jeffrey Carpenter Maurice Buchbinder Rajesh Dave Gary Ansel Alexandra Lansky Ecaterina Cristea Tyrone J. Collins Jeffrey Goldstein Michael R. Jaff | 2010 | Circulation: Cardiovascular Interventions2010，，： | 2 |
| 4 | Acute Heart Failure Syndromes: Emergency Department Presentation, Treatment, and Disposition: Current Approaches and Future Aims: A Scientific Statement From the American Heart Association显示文摘 | Neal L. Weintraub Sean P. Collins Peter S. Pang Phillip D. Levy Allen S. Anderson Cynthia Arslanian-Engoren W. Brian Gibler James K. McCord Mark B. Parshall Gary S. Francis Mihai Gheorghiade | 2010 | Circulation2010，，： | 1 |
| 5 | Eosinophilic esophagitis: Updated consensus recommendations for children and adults显示文摘 | Chris A. Liacouras Glenn T. Furuta Ikuo Hirano Dan Atkins Stephen E. Attwood Peter A. Bonis A. Wesley Burks Mirna Chehade Margaret H. Collins Evan S. Dellon Ranjan Dohil Gary W. Falk Nirmala Gonsalves Sandeep K. Gupta David A. Katzka Alfredo J. Lucendo Jo | 2011 | The Journal of Allergy and Clinical Immunology2011，，1： | 1 |
| 6 | Place and provision of palliative care for children with progressive cancer:a study by the paediatric oncology nurses‘ forum/united kingdom children' s cancer study group palliative care working group显示文摘 | Vickers Jan Thompson Anne Collins Gary S | 2007 | Journal of Clinical Oncology2007，25，28： | 1 |
| 7 | Comparing gel permeation chromatography and ultrafiltration for the molecular weight characterization of aquatic organic matter显示文摘 | Gary L Amy Michael R Collins | 1987 | JAWWA1987，，： | 1 |
| 8 | Molecular weight distribution, carboxylic acidity and humic substances content of aquatic organic matter: implications for removal during water treatment显示文摘 | Michael R Collins Gary L Amy | 1986 | Environ Sci Technol1986，20，10： | 1 |
| 9 | Molecular weight distribution,carboxylic acidity,and humic substances content of aquatic organic matter:implications for removal during water treatment显示文摘 | Gary L Amy Cornellus Steelink | 1986 | Environ Sci Technol1986，20，： | 1 |
| 10 | Contribution of Stent Underexpansion to Recurrence After Sirolimus-Eluting Stent Implantation for In-Stent Restenosis显示文摘 | Kenichi Fujii Gary S. Mintz Yoshio Kobayashi Stéphane G. Carlier Hideo Takebayashi Takenori Yasuda Issam Moussa George Dangas Roxana Mehran Alexandra J. Lansky Arlene Reyes Edward Kreps Michael Collins Antonio Colombo Gregg W. Stone Paul S. Teirstein Mart | 2004 | Circulation: Journal of the American Heart Association2004，，9： | 1 |
| 11 | Nonalcoholic Fatty Liver Disease (NAFLD) among H/V-Infected Persons 显示文摘 | Nancy Crum-Cianflone Angelica Dilay Gary Collins | 2009 | J Acquit Immune Defie Syndr2009，50，5： | 1 |
| 12 | Stent underexpansion and residual reference segment stenosis are related to stent thrombosis after sirolimus-eluting stent implantation显示文摘 | Kenichi Fujii Stéphane G. Carlier Gary S. Mintz Yi-ming Yang Issam Moussa Giora Weisz George Dangas Roxana Mehran Alexandra J. Lansky Edward M. Kreps Michael Collins Gregg W. Stone Jeffrey W. Moses Martin B. Leon | 2005 | Journal of the American College of Cardiology2005，，7： | 1 |
| 13 | Seasonal variation in blood pressure and its relationship with outdoor temperature in 10 diverse regions of China: the China Kadoorie Biobank显示文摘 | Sarah Lewington Liming Li Paul Sherliker Yu Guo Iona Millwood Zheng Bian Gary Whitlock Ling Yang Rory Collins Junshi Chen Xianping Wu Shaojie Wang Yihe Hu Li Jiang Liqiu Yang Ben Lacey Richard Peto Zhengming Chen | 2012 | Journal of Hypertension2012，，7： | 1 |
| 14 | Nitinol Stent Implantation Versus Balloon Angioplasty for Lesions in the Superficial Femoral Artery and Proximal Popliteal Artery: Twelve-Month Results From the RESILIENT Randomized Trial显示文摘 | John R. Laird Barry T. Katzen Dierk Scheinert Johannes Lammer Jeffrey Carpenter Maurice Buchbinder Rajesh Dave Gary Ansel Alexandra Lansky Ecaterina Cristea Tyrone J. Collins Jeffrey Goldstein Michael R. Jaff | 2010 | Circulation: Cardiovascular Interventions2010，，3： | 1 |
| 15 | Vascular remodeling and plaque composition between focal and diffuse coronary lesions assessed by intravascular ultrasound显示文摘 | Kenichi Fujii Gary S. Mintz Yoshio Kobayashi Stéphane G. Carlier Hideo Takebayashi David Jacoboff Takenori Yasuda Issam Moussa George Dangas Roxana Mehran Alexandra J. Lansky Arlene Reyes Edward Kreps Michael Collins Gregg W. Stone Martin B. Leon Jeffrey | 2004 | The American Journal of Cardiology2004，，8： | 1 |
| 16 | Intravascular ultrasound assessment of the incidence and predictors of edge dissections and intramural hematomas after drug-eluting stent implantation显示文摘Objective We used intravascular ultrasound (IVUS) to assess incidence, predictors, morphology, and angiographic findings of edge dissections and intramural hematomas after drug-eluting stent (DES) implantation. Methods We studied 887 patients with 1 045 non-in-stent restenosis lesions in 977 native arteries undergoing DES implantation with IVUS imaging, and compared the dissected stent end to the non-dissected stent end. Results Eighty-two dissections were detected; 51.2% (42/82) involved the proximal and 48.8% (40/82) the distal stent edge. When compared to the non-dissected stent end, residual plaque area [(8.0±4.3) mm2 vs (5.2±3.0) mm2, P<0.01], plaque burden [(52±12)% vs (36±15)%, P<0.01], plaque eccentricity (8.4±5.5 vs 4.0±3.4, P<0.01), and stent edge symmetry (1.17±0.11 vs 1.14±0.08, P=0.02) were larger; plaque burden≥50% was more frequent (62% vs 17%, P<0.01) and calcium deposits (52.5% vs 35.6%, P=0.03) more common; and the lumen/stent area (0.86±0.16 vs 1.02±0.18, P<0.01) was smaller in the stent dissected end. Independent predictors of stent edge dissection were residual plaque eccentricity (OR=1.3, P<0.01) and residual plaque burden≥50% (OR=7.3, P<0.01). Intramural hematomas occurred in 34.1% (28/82) of dissections.Independent predictors of intramural hematomas were plaque eccentricity (OR=1.4, P=0.005), plaque burden≥50% (OR=7.1, P=0.02), and mean lumen diameter to stent diameter ratio (OR=0.37, P=0.04).Concluslon IVUS identified edge dissections after 9.4% of DES implantations. Residual plaque eccentricity and significant plaque burden predicted coronary stent edge dissections. Dissections in less diseased reference segments with an arc of normal vessel wall (greater plaque eccentricity) more often evolved into an intramural hematoma. | Gary S.Mintz Stéphane G.Carlier Jose de Ribamar Costa Jr Koichi Sano Joanna Lui Giora Weisz Issam Moussa George D.Dangas Roxana Mehran Edward M.Kreps Michael Collins Gregg W.Stone Jeffrey W.Moses GE Junbo Martin B.Leon | 2007 | 上海医学2007，30，S1： | 0 |
| 17 | 星际探索 卓瑞尔天文台“第一道光”射电天文馆显示文摘“第一道光”射电天文馆由建筑事务所Hassell设计。该项目建成开放后,世界各地的访客在著名的卓瑞尔天文台的参观体验得到很大提升,他们将射电天文学理论,转化成了迷人的星际探索。作为这块场地上最大的公共建筑,展馆的设计以捕捉太空爱好者的好奇心为主旨,引发人们科学探索的欲望,在广袤无垠太空收获天文学的发现。 | Julian Gitsham Gary Collins Adam Atraktzi Oliver Kampshoff Sarah Willats Clive Lewis Kaja Swiezewska Trang Dao David Brown(摄影) | 2023 | 室内设计与装修2023，，6： | 0 |
| 18 | Assessment of inconclusive left main coronary lesions: lessons from an intravascular ultrasound study显示文摘Objective Angiographic assessment of a left main coronary artery (LMCA) stenosis is often difficult and unreliable. Intravascular ultrasound (IVUS) assessment of absolute lumen dimensions has been shown to correlate with fractional flow reserve (FFR) and to predict clinical outcome in patients with a LMCA stenosis. Methods During 21 months period (October, 2004 to July, 2006), 153 patients (Ostial lesions, n=47; Non-ostial lesion, n=106) underwent IVUS evaluation specifically to assess the severity of an angiographically inconclusive LMCA narrowing. IVUS analysis included plaque morphology; external elastic membrane (EEM), lumen, plaque cross-sectional areas (CSA), plaque burden (plaque CSA/ EEM) and remodeling index (lesion EEM CSA/reference EEM CSA). Results Overall, minimum lumen area (MLA) and diameter (MLD) and plaque burden measured 8.2 mm2, 2.6 mm, and 59.3 %, respectively. An MLA<6.0 mm2 (which has been shown to correlate with a FFR <0.75) was seen 41.5% in ostial lesions and 44.5% in non-ostial lesions. In particular, ostial LMCA lesions had a larger MLA and a smaller plaque burden than non-ostial lesions (Table). Conclusions Patients referred for LMCA evaluation commonly have insignificant narrowing. Negative remodeling was prominent at the LMCA ostium. These patients deserve IVUS assessment before revascularization. | Gary S.Mintz Stéphane G.Carlier Jose de Ribamar Costa Jr Koichi Sano Joanna Lui Giora Weisz Issam Moussa George D.Dangas Roxana Mehran Edward M.Kreps Michael Collins Gregg W.Stone Jeffrey W.Moses Junbo Ge Martin B.Leon | 2007 | 上海医学2007，30，S1： | 0 |
| 19 | Volumetric intravascular ultrasound comparisons of drug-eluting stent thrombosis and in-stent restenosis显示文摘Objectives We compared intravascular ultrasound (IVUS) findings of drug-eluting stent (DES)-treated lesions that developed stent thrombosis versus in-stent restenosis (ISR) to identify underlying mechanical differences. Methods IVUS findings in 15 post-DES thrombosis patients were compared with 45 matched ISR patients who had no evidence of stent thrombosis. Results Minimum stent area [MSA, (3.7±0.8) mm2 vs (4.9±1.8) mm2, P=0.01], minimum stent diameter [(1.9±0.3) mm vs (2.3±0.4) mm, P=0.005], mean stent area [(5.2±0.8) mm2 vs (7.2±2.1) mm2, P<0.01], and both focal [MSA/reference lumen area, (54.7±15.9)% vs (75.0±20.1)%, P=0.001] and diffuse stent expansion [mean stent area/reference lumen area, (76.6±23.0)% vs (110.3±23.3)%, P<0.01] were significantly smaller in the stent thrombosis group (vs the ISR group). An MSA <4.0 mm2 (73.3% vs 35.6%, P=0.01) or <5.0 mm2 (86.7% vs 53.3%, P=0.02) was more often found in the stent thrombosis group (vs the ISR group). The MSA site occurred more frequently in the proximal stent segment within the stent thrombosis group compared to the ISR group (60% vs 24.4%, P=0.01). There were no differences in edge dissection, stent fracture, or stent-vessel wall malapposition between the two groups. Independent predictors of stent thrombosis were diffuse stent expansion (OR=1.5, P=0.03) and proximal location of the MSA site (OR=12.7, P=0.04). Conclusion DES-treated lesions that develop thrombosis or restenosis are often underexpanded. Underexpansion appears to be more severe in DES-thrombosis lesions. Lesions with diffuse underexpansion and a proximal (vs distal) underexpanded MSA site are more predisposed to thrombus formation than ISR. | Gary S.Mintz Stéphane G.Carlier Jose de Ribamar Costa Jr Koichi Sano Joanna Lui Giora Weisz Issam Moussa George D.Dangas Roxana Mehran Edward M.Kreps Michael Collins Gregg W.Stone Jeffrey W.Moses GE Junbo Martin B.Leon | 2007 | 上海医学2007，30，S1： | 0 |
| 20 | Effect of airplane transport of donor livers on post-liver transplantation survival显示文摘AIM To evaluate the effect of long haul airplane transport of donor livers on post-transplant outcomes. METHODS A retrospective cohort study of patients who received a liver transplantation was performed in Perth, Australia from 1992 to 2012. Donor and recipient characteristics information were extracted from Western Australian liver transplantation service database. Patients were followed up for a mean of six years. Patient and graft survival were evaluated and compared between patients who received a local donor liver and those who received an airplane transported donor liver. Predictors of survival were determined by univariate and multivariate analysis using cox regression.RESULTS One hundred and ninety-three patients received alocal donor liver and 93 patients received an airplane transported donor liver. Airplane transported livers had a significantly lower alanine transaminase(mean: 45 U/L vs 84 U/L, P = 0.035), higher donor risk index(mean: 1.88 vs 1.42, P < 0.001) and longer cold ischemic time(CIT)(mean: 10.1 h vs 6.4 h, P < 0.001). There was a weak correlation between CIT and transport distance(r2 = 0.29, P < 0.001). Mean follow up was six years and 93 patients had graft failure. Multivariate analysis found only airplane transport retained significance for graft loss(HR = 1.92, 95%CI: 1.16-3.17). One year graft survival was 0.88 for those with a local liver and was 0.71 for those with an airplane transported liver. One year graft loss was due to primary graft non-function or associated with preservation injury in 20.8% of recipients of an airplane transported liver compared with 4.6% in those with a local liver(P = 0.027). CONCLUSION Airplane transport of donor livers was independently associated with reduced graft survival following liver transplantation. | Yi Huang Gerry MacQuillan Leon A Adams George Garas Megan Collins Albert Nwaba Linjun Mou Max K Bulsara Luc Delriviere Gary P Jeffrey | 2016 | World Journal of Gastroenterology2016，22，41： | 0 |
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