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| 1 | 沉积物粒径趋势与海洋沉积动力学显示文摘沉积物粒度数据除可用来识别沉积环境的类型或判定物质运动方式之外,还可用于海洋环境中沉积物输运方向的研究,即将沉积物净输运方向与粒度参数的空间变化(粒径趋势)相联系。利用粒径趋势分析,可根据粒度参数的平面分布图式定义粒径趋势矢量,进而将趋势矢量转换为沉积物净输运图像。粒径趋势分析的基本假设是,沿着净输运方向,某种粒径趋势出现的概率远高于其在别的方向上出现的概率。初步研究表明这个假设是成立的,但今后还需要从物理原理上说明粒径趋势与颗粒态物质运动的关系,从水槽实验和数学模型实验入手,进一步完善这一分析方法。以促进粒度特征研究乃至颗粒态物质动力学的进步。 | 高抒 Michael Collins | 1998 | 中国科学基金1998，12，4： | 59 |
| 2 | The hypoxia-inducible factor-1α activates ectopic production of fibroblast growth factor 23 in tumor-induced osteomalacia显示文摘Tumor-induced osteomalacia(TIO) is a rare paraneoplastic syndrome in which ectopic production of fibroblast growth factor 23(FGF23) by non-malignant mesenchymal tumors causes phosphate wasting and bone fractures. Recent studies have implicated the hypoxia-inducible factor-1α(HIF-1α) in other phosphate wasting disorders caused by elevated FGF23, including X-linked hypophosphatemic rickets and autosomal dominant hypophosphatemia. Here we provide evidence that HIF-1α mediates aberrant FGF23 in TIO by transcriptionally activating its promoter. Immunohistochemical studies in phosphaturic mesenchymal tumors resected from patients with documented TIO showed that HIF-1α and FGF23 were co-localized in spindleshaped cells adjacent to blood vessels. Cultured tumor tissue produced high levels of intact FGF23 and demonstrated increased expression of HIF-1α protein. Transfection of MC3T3-E1 and Saos-2 cells with a HIF-1α expression construct induced the activity of a FGF23 reporter construct. Prior treatment of tumor organ cultures with HIF-1α inhibitors decreased HIF-1α and FGF23 protein accumulation and inhibited HIF-1α-induced luciferase reporter activity in transfected cells. Chromatin immunoprecipitation assays confirmed binding to a HIF-1α consensus sequence within the proximal FGF23 promoter, which was eliminated by treatment with a HIF-1α inhibitor. These results show for the first time that HIF-1α is a direct transcriptional activator of FGF23 and suggest that upregulation of HIF-1α activity in TIO contributes to the aberrant FGF23 production in these patients. | Qian Zhang Michele Doucet Ryan E Tomlinson Xiaobin Han L Darryl Quarles Michael T Collins Thomas L Clemens | 2016 | Bone Research2016，4，2： | 6 |
| 3 | Positron emission tomography scanning in the evaluation of hepatocellular carcinoma显示文摘 | M.Akram Khan Connie S Combs Elizabeth M Brunt Val J Lowe Michael K Wolverson Harvey Solomon Brian T Collins Adrian M.Di Bisceglie | 2000 | Journal of Hepatology2000，，5： | 2 |
| 4 | An approach for greenway suitability analysis显示文摘 | William Miller Michael G. Collins Frederick R. Steiner Edward Cook | 1998 | Landscape and Urban Planning1998，，2： | 2 |
| 5 | Nitinol Stent Implantation Versus Balloon Angioplasty for Lesions in the Superficial Femoral Artery and Proximal Popliteal Artery: Twelve-Month Results From the RESILIENT Randomized Trial显示文摘 | John R. Laird Barry T. Katzen Dierk Scheinert Johannes Lammer Jeffrey Carpenter Maurice Buchbinder Rajesh Dave Gary Ansel Alexandra Lansky Ecaterina Cristea Tyrone J. Collins Jeffrey Goldstein Michael R. Jaff | 2010 | Circulation: Cardiovascular Interventions2010，，： | 2 |
| 6 | The Information of Historical Cost Earnings Relative to Supplemental Reserve-Based Accounting Data in the Extractive Petroleum Industry显示文摘 | B Michael Doran Daniel W Collins Dan S Dhaliwal | 1988 | The Accounting Review1988，63，3： | 1 |
| 7 | Where is Shear Reinforcement Required? Review of Research Results and Design Procedures显示文摘 | Collins Michael P Bentz Evan C Sherwood Edward G | 2008 | ACI Structural Journal2008，，5： | 1 |
| 8 | A practical method for calculating largest Lyapunov exponents from small data sets显示文摘 | Rosenstein Michael T Collins De | 1993 | Phys D1993，65，12： | 1 |
| 9 | A Randomized, Double-Blind, Placebo-Controlled Trial of Fluticasone Propionate for Pediatric Eosinophilic Esophagitis显示文摘 | Michael R. Konikoff Richard J. Noel Carine Blanchard Cassie Kirby Sean C. Jameson Bridget K. Buckmeier Rachel Akers Mitchell B. Cohen Margaret H. Collins Amal H. Assa’ad Seema S. Aceves Philip E. Putnam Marc E. Rothenberg | 2006 | Gastroenterology2006，，： | 1 |
| 10 | A practical method for calculating largest Lyapunovexponents from small data sets显示文摘 | Rosenstein Michael T Collins James J Luca Carlo J De | 1993 | Physica D: Nonlinear Phenomena1993，65，12： | 1 |
| 11 | Dry deposition of gaseous elemental mercury to plants and soils using mercury stable isotopes in a controlled environment显示文摘 | Andrew P. Rutter James J. Schauer Martin M. Shafer Joel E. Creswell Michael R. Olson Michael Robinson Ryan M. Collins Andrew M. Parman Tanya L. Katzman Justin L. Mallek | 2010 | Atmospheric Environment2010，，4： | 1 |
| 12 | Long-term effects of continuing adjuvant tamoxifen to 10 years versus stopping at 5 years after diagnosis of oestrogen receptor-positive breast cancer: ATLAS, a randomised trial显示文摘 | Christina Davies Hongchao Pan Jon Godwin Richard Gray Rodrigo Arriagada Vinod Raina Mirta Abraham Victor Hugo Medeiros Alencar Atef Badran Xavier Bonfill Joan Bradbury Michael Clarke Rory Collins Susan R Davis Antonella Delmestri John F Forbes Peiman Hadd | 2012 | The Lancet2012，，： | 1 |
| 13 | Strut-and-tie models for the design of pile caps: an experimental study 显示文摘 | Perry Adebar Daniel Kuchma Michael P Collins | 1990 | ACI Structural Journal1990，87，1： | 1 |
| 14 | Application of the CALIOP layer product to evaluate the vertical distribution of aerosols estimated by global models: AeroCom phase I results显示文摘 | Koffi Brigitte Schulz Michael Bréon Francois-Marie Griesfeller Jan Winker David Balkanski Yves Bauer Susanne Berntsen Terje Chin Mian Collins William D. Dentener Frank Diehl Thomas Easter Richard Ghan Steven Ginoux Paul Gong Sunling Horowi | 2012 | EN2012，，1： | 1 |
| 15 | An energy - conserving parabolic equation for elastic media显示文摘 | MICHAEL D COLLINS | 1993 | JASA1993，94，： | 1 |
| 16 | Fecal Water as a Non-Invasive Biomarker in Nutritional Intervention: Comparison of Preparation Methods and Refinement of Different Endpoints显示文摘 | Annett Klinder Pernilla C. Karlsson Yvonne Clune Roisin Hughes Michael Glei Joseph J. Rafter Ian Rowland John K. Collins Beatrice L. Pool-Zobel | 2007 | Nutrition and Cancer2007，，2： | 1 |
| 17 | CARD15 gene mutations and risk for early surgery in pediatric-onset Crohn’s disease显示文摘 | Subra Kugathasan Nicole Collins Karen Maresso Raymond G. Hoffmann Michael Stephens Steven L. Werlin Colin Rudolph Ulrich Broeckel | 2004 | Clinical Gastroenterology and Hepatology2004，，11： | 1 |
| 18 | A study of the role of ion–molecule chemistry in the formation of sporadic sodium layers显示文摘 | Stephen C. Collins John M.C. Plane Michael C. Kelley Timothy G. Wright Pavel Soldán Timothy J. Kane Andrew J. Gerrard Brent W. Grime Rosie J. Rollason Jonathan S. Friedman Sixto A. González Qihou Zhou Michael P. Sulzer Craig A. Tepley | 2002 | Journal of Atmospheric and Solar-Terrestrial Physics2002，，7： | 1 |
| 19 | Head-driven statistical models for natural language parsing 显示文摘 | Collins Michael | 2003 | Computational linguistics2003，29，4： | 1 |
| 20 | Myeloid Differentiation Primary Response Protein 88 Couples Reverse Cholesterol Transport to Inflammation显示文摘 | Kathleen A. Smoak Jim J. Aloor Jennifer Madenspacher B. Alex Merrick Jennifer B. Collins Xuewei Zhu Giorgio Cavigiolio Michael N. Oda John S. Parks Michael B. Fessler | 2010 | Cell Metabolism2010，，： | 1 |
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