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| 1 | Aluminum potassium sulfate and tannic acid sclerotherapy for Goligher Grades Ⅱ and Ⅲ hemorrhoids: Results from a multicenter study显示文摘AIM: To show that aluminum potassium sulfate and tannic acid(ALTA) sclerotherapy has a high success rate for Grade Ⅱ and Ⅲ hemorrhoids.METHODS: This study was based on the clinical data of 604 patients with hemorrhoids who underwent ALTA sclerotherapy between January 2009 and February 2015. The objective of this study was to assess the efficacy of this treatment for Grades Ⅱ and Ⅲ hemorrhoids. Preoperative and postoperative symptoms, complications and success rate were all assessed retrospectively. Follow-up consisted of a simple questionnaire, physical examination and an anoscopy. Patients were followed-up at one day, one week, two weeks, one month, one year, two years, three years, four years and five years after the ALTA sclerotherapy.RESULTS: One hundred and sixty-nine patients were diagnosed with Grade Ⅱ hemorrhoids and 435 patients were diagnosed with Grade Ⅲ hemorrhoids. The one year, three year and five year cumulative success rates of ALTA sclerotherapy for Grades Ⅱ and Ⅲ hemo-rrhoids were 95.9% and 93.1%; 89.3% and 83.7%; and 89.3% and 78.2%, respectively. No significant differences were observed in the cumulative success rates after ALTA sclerotherapy between Grades Ⅱ and Ⅲ hemorrhoids(P = 0.09). There were forty-seven post-operative complications(low grade fever; anal pain; urinary retention; rectal ulcer; and others). No serious or life-threatening complications occurred and all cases improved through conservative treatment. At univariate analysis there were no predictive factors of failure.CONCLUSION: ALTA sclerotherapy has had a high success rate for Grade Ⅱ and Ⅲ hemorrhoids during five years of post-operative treatment. However, additional studies are needed to evaluate the efficacy of this ALTA sclerotherapy in the management of hemorrhoidal disease. | Hidenori Miyamoto Takenori Hada Gentaro Ishiyama Yoshito Ono Hideo Watanabe | 2016 | World Journal of Hepatology2016，8，20： | 10 |
| 2 | Autoimmune pancreatitis with IgG4-positive plasma cell infiltration in salivary glands and biliary tract显示文摘A 62-year-old male was referred to our hospital because of liver dysfunction, diffuse pancreatic swelling, and trachelophyma. At admission, the patient was free of pain.Physical examination showed enlarged and palpable bilateral submandibular masses, but no palpable mass or organomegaly in the abdomen. Laboratory findings were as follows: total protein 90 g/L with γ-globulin of 37.3% (33 g/L), total bilirubin 4 mg/L, aspartate aminotransferase 39 IU/L, alanine aminotransferase 67 IU/L, γ-glutamyl transpeptidase 1 647 IU/L, and amylase 135 IU/L. Autoantibodies were negative, and tumor markers were within the normal range. Serum IgG4 level was markedly elevated (18 900 mg/L). Computed tomography (CT) showed diffuse swelling of the pancreas and dilatation of both common and intra-hepatic bile ducts. Endoscopic retrograde pancreatography (ERP) revealed diffuse irregular and narrow main pancreatic duct and stenosis of the lower common bile duct. Biopsy specimens from the pancreas, salivary gland and liver showed marked periductal IgG4-positive plasma cell infiltration with fibrosis. We considered this patient to be autoimmune pancreatitis (AIP) with fibrosclerosis of the salivary gland and biliary tract, prescribed prednisolone at an initial dose of 40 mg/d. Three months later, the laboratory data improved almost to normal. Abdominal CT reflected prominent improvement in the pancreatic lesion. Swelling of the salivary gland also improved. At present, the patient is on 10 mg/d of prednisolone without recurrence of the pancreatitis. We present here a case of AIP with fibrosclerosis of salivary gland and biliary tract. | Masashi Taguchi Gentaro Aridome Shintaro Abe Keiichiro Kume Mitsuo Tashiro Mitsuyoshi Yamamoto Yasuyuki Kihara Hayato Nakamura Makoto Otsuki | 2005 | World Journal of Gastroenterology2005，11，35： | 5 |
| 3 | Anal cushion lifting method is a novel radical management strategy for hemorrhoids that does not involve excision or cause postoperative anal complications显示文摘AIM: To describe the anal cushion lifting(ACL) method with preliminary clinical results. METHODS: Between January to September 2007, 127 patients who received ACL method for hemorrhoid was investigated with informed consent. In this study, three surgeons who specialized in anorectal surgery performed the procedures. Patients with grade two or more severe hemorrhoids according to Goligher's classification were considered to be indicated for surgery. The patients were given the choice to undergo either the ACL method or theligation and excision method. ACL method is an original technique for managing hemorrhoids without excision. After dissecting the anal cushion from the internal sphincter muscle, the anal cushion was lifted to oral side and ligated at the proper position. Clinical characteristics and outcomes of patients were recorded including complications after surgery. RESULTS: A total of 127 patients were enrolled. Their median age was 42(19-84) years, and 74.8% were female. In addition, more than 99% of the patients had grade 3 or worse hemorrhoids. The median followup period was 26(0-88) mo, and the median operative time was 15(4-30) min. After surgery, analgesics were used for a median period of three days(0-21). Pain control was achieved using extra-oral analgesic drugs, although some patients required intravenous injections of analgesic drugs. The median duration of the patients' postoperative hospital stay was 7(2-13) d. A total of 10 complications(7.9%) occurred. Bleeding was observed in one patient and was successfully controlled with manual compression. Urinary retention occurred in 6 patients, but it disappeared spontaneously in all cases. Recurrent hemorrhoids developed in 3 patients after 36, 47, and 61 mo, respectively. No anal stenosis or persistent anal pain occurred. CONCLUSION: We consider that the ACL method might be better than all other current methods for managing hemorrhoids. | Gentaro Ishiyama Toshihiko Nishidate Yuji Ishiyama Akihiko Nishio Ken Tarumi Maiko Kawamura Kenji Okita Toru Mizuguchi Mineko Fujimiya Koichi Hirata | 2015 | World Journal of Gastrointestinal Surgery2015，7，10： | 3 |
| 4 | Interleukin-lb stimulates the secretion of thymic stromal lymphopoietin (TSLP) from endometrioma stromal cells: possible involvement of TSEP in endometriosis显示文摘 | Yoko Urata Yutaka Osuga Gentaro Izumi | 2012 | Hum Reprod2012，27，10： | 1 |
| 5 | A model of neuro-mus- cule-skeletal system for anticipatory adjust- ment of human locomotion during obstacle avoidance显示文摘 | Hatze Gentaro Taga | 1988 | Biological Cybernetics1988，78，： | 1 |
| 6 | Toll‐like Receptors at the Maternal‐Fetal Interface in Normal Pregnancy and Pregnancy Complications显示文摘 | Kaori Koga Gentaro Izumi Gil Mor Tomoyuki Fujii Yutaka Osuga | 2014 | Am J Reprod Immunol2014，，2： | 1 |
| 7 | A model of the neuro-musculo-skeletalsystem for human locomotion显示文摘 | GENTARO T | 1995 | Biological Cybernetics1995，，73： | 1 |
| 8 | Importance of binding states between photosensitizing molecules and the TiO2 surface for efficiency in a dye-sensitized solar ceil显示文摘 | Kei M Gentaro K | 1995 | J Electroanalytical Chemistry1995，396，： | 1 |
| 9 | Migration of lens epithelial cells through haptic root of single-piece acrylic-foldable intraocular lens显示文摘 | Miho Sugita Satoshi Kato Gentaro Sugita Tetsuro Oshika | 2003 | American Journal of Ophthalmology2003，，2： | 1 |
| 10 | New approach to relieving pain and distress during high-dose-rate intracavitaly irradiation fon:ervical cancer 显示文摘 | Miho Wa|anabe Nemoto Natsuko Nozaki-Taguchi Gentaro Togasaki | 2015 | Brachytherapy2015，14，5： | 1 |
| 11 | A model of the neuro-musculo-skeletal system for anticipatory adjustment of human locomotion during obstacle avoidance显示文摘 | Gentaro Taga | 1998 | Biological Cybernetics1998，，1： | 1 |
| 12 | A model of the neuro-musculo-skeletal system for human locomotion显示文摘 | Gentaro Taga | 1995 | Biological Cybernetics1995，，2： | 1 |
| 13 | The Relationship Between the Anatomy of the Nuchal Ligament and Postoperative Axial Pain After Cervical Laminoplasty: Cadaver and Clinical Study显示文摘 | Atsushi Ono Yoshikazu Tonosaki Takuya Numasawa Kanichiro Wada Yoshihito Yamasaki Toshihiro Tanaka Gentaro Kumagai Shuichi Aburakawa Kazunari Takeuchi Toru Yokoyama Kazumasa Ueyama Yasuyuki Ishibashi Satoshi Toh | 2012 | Spine2012，，26： | 1 |
| 14 | Themolecular action and reg-ulation of the testis determining factors,SRY and Sox9显示文摘 | Harley V R ArksonM J Gentaro A | | 0，，04： | 1 |
| 15 | Fast volumepreserving free form deformation using multi-level optimization显示文摘 | Gentaro Hirota Renee Maheshwari Ming C Lin | 2000 | Computer-Aided Design2000，32，89： | 1 |
| 16 | Epidermal hyperpigmentation in non-syndromic solitary cafe-au-lait macules may be associated with increased secretion of endothelin-1 by lesional keratinocytes显示文摘 | Mutsumi Okazaki Kotaro Yoshimura Gentaro Uchida Yasutoshi Suzuki Yukie Kitano Kiyonori Harii | 2005 | Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery2005，，4： | 1 |
| 17 | The molecular action and regulation of the testis determining factors, SRY and Sox9 显示文摘 | HARLEY V R ARKSON M J GENTARO A | 2003 | Endocrine Reviews2003，24，4： | 1 |
| 18 | Activin-A is induced by interleukin-1β and tumor necrosis factor-α and enhances the mRNA expression of interleukin-6 and protease-activated receptor-2 and proliferation of stromal cells from endometrioma显示文摘 | Osamu Yoshino Gentaro Izumi Jia Shi Yutaka Osuga Yasushi Hirota Tetsuya Hirata Miyuki Harada Osamu Nishii Kaori Koga Yuji Taketani | 2011 | Fertility and Sterility2011，，1： | 1 |
| 19 | Importance of binding states between photosensitizing molecules and the TiO2 surface for efficiency in a dye-sensitized solar cell 显示文摘 | Kei Murakoshi Gentaro Kano Yuji Wada | 1995 | J Electroanal Chem1995，396，： | 1 |
| 20 | Development of Ethernet Terminal Adapter 显示文摘 | HARADA KEIJI OKAMOTO OSAMU FUNATSU GENTARO | 2002 | NTT Review2002，14，4： | 1 |
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