|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Ovicidal and repellent activities of botanical extracts against Culex quinquefasciatus,Aedes aegypti and Anopheles stephensi(Diptera:Culicidae)显示文摘Objective:To determine the ovicidal and repellent activities of methanol leaf extract of Ervatamia coronaria(E.coronaria) and Caeslpinia pulckerrima(C.pulcherrima) against Culex quinquefasciatus(Cx.quinquefasciatus),Aedes aegypti(Ae.aegypti) and Anopheles stephensi(An. stephensi).Methods:The ovicidal activity was determined against three mosquito species at various concentrations ranging from 50-450 ppm under the laboratory conditions.The hatch rates were assessed 48 h after treatment.The repellent efficacy was determined against three mosquito species at three concentrations viz.,1.0,2.5 and 5.0 mg/cm under the laboratory conditions. Results:The crude extract of E.coronaria exerted zero hatchability(100%mortality) at 250.200 and 150 ppm for Cx.quinqitefasciatus,Ae.aegypti and An.stephensi,respectively.The crude extract of C.pulchenima exerted zero hatchability(100%mortality) at 375.300 and 225 ppm for Cx.quinquefasciatus,Ae.aegypti and An.Stephensi,respectively.The methanol extract of E. coronaria found to be more repellenct than C.pukherrima extract.A higher concentration of 5.0 mg/cm^2 provided 100%protection up to 150.180 and 210 min against Cx.quinquefasciatus,Ae. aegypti and An.stephensi,respectively.The results clearly showed that repellent activity was dose dependent.Conclusions:From the results it can be concluded the crude extracts of E.coronaria and C.pukherrima are an excellent potential for controlling Cx.quinquefasciatus,Ae.aegypti and An.stephensi mosquitoes. | Govindarajan M Mathivanan T Elumalai K Krishnappa K Anandan A | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，1： | 17 |
| 2 | Mosquito larvicidal and ovicidal properties of Eclipta alba(L.) Hassk(Asteraceae) against chikungunya vector,Aedes aegypti(Linn.)(Diptera:Culicidae)显示文摘Objective:The present study deals with the investigation of larvicidal and ovicidal activities of benzene,hexane,ethyl acetate,methanol and chloroform leaf extract of Eclipta alba(E.alba) against dengue vector,Aedes aegypti(Ae.Aegypti).Methods:Twenty five earlyⅢinstar larvae of Ae.aegypti was exposed to various concentrations(50-300 ppm) and was assayed in the laboratory by using the protocol of WHO 2005;the 24 h LC50 values of the E.alba leaf extract was determined by Probit analysis.For ovicidal activity,slightly modified method of Su and Mulla was performed.The ovicidal activity was determined against Ae.aegypti to various concentrations ranging from 100-350 ppm under the laboratory conditions.The egg hatch rates were assessed 48 h post treatment.Results:The LC50 values of benzene,hexane,ethyl acetate,methanol and chloroform extract of E.alba against early third instar larvae of Ae.aegypti were 151.38,165.10, 154.88,127.64 and 146.28 ppm,respectively.Maximum larvicidal activity was observed in the methanol extract followed by chloroform,benzene,ethyl acetate and hexane extract.No mortality was observed in control.Among five solvent tested the methanol extract was found to be most effective for ovicidal activity against Ae.aegypti.The methanol extracts exerted 100%mortality (zero hatchability) at 300 ppm.Conclusions:From the results it can be concluded the crude extract of E.alba was an excellent potential for controlling Ae.aegypti mosquito. | M Govindarajan P Karuppannan | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，1： | 10 |
| 3 | Chemical composition and larvicidal activity of leaf essential oil from Clausena anisata (Willd.) Hook.f.ex Benth (Rutaceae) against three mosquito species显示文摘Objective:To determine the mosquito larvicidal activity of leaf essential oil and their chemical constituents from Clausena anisata(C.anisata)(Willd.) Hook.f.ex Benth.against Culex quinquefasciatus,Aedes aegypti and Anopheles Stephensi.Methods:Essential oil was obtained by hydro-distillation and the chemical composition of the leaf essential oil was analyzed using gas chromatography—mass spectrometry.The mosquitoes were reared in the vector control laboratory and twenty lateⅢinstar larvae of three mosquito species were exposed to based on the wide range and narrow range tests,essential oil was tested at 50.100.150,200 and 250 ppm and each compound was tested at various concentration(5-75 ppm) and were assayed in the laboratory by using the protocol of WHO 2005:the 24 h LC50 values of the C.anisata leaf essential oil and their major compounds were determined following Probit analysis.Results:The oil contained were mainlyβ-pinene(32.8%),sabinene(28.3%),germacrene-D(12.7%),estragole (6.4%) and linalool(5.9%).The essential oil from the leaves of C.anisata exhibited significant larvicidal activity,with 24 h LC50 values of 140.96,130.19 and 119.59 ppm.respectively.The five pure constituents extracted from the C.anisata leaf essential oil were also tested individually against three mosquito larvae.The LC50 values ofβ-pinene,sabinene,germacrene-D,estragole and linalool appeared to be most effective against Anopheles stephensi(LC50-23.17,19.67,16.95. 11.01,35.17 ppm) followed by Aedes aegypti(LC50-27.69,21.20,18.76,12.70,38.64 ppm) and Culex quinquefasciatus(LC50-32.23,25.01.21.28,14.01,42.28).Conclusions:The essential oil of C. anisata contains five major compounds and has remarkable larvicidal properties,which may be considered as a potent source for the production of natural larvicides. | Marimuthu Govindarajan | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，11： | 9 |
| 4 | Larvicidal and ovicidal activity of Cassia fistula Linn. leaf extract against filarial and malarial vector mosquitoes显示文摘 | M. Govindarajan A. Jebanesan T. Pushpanathan | 2008 | Parasitology Research2008，，2： | 8 |
| 5 | Metastasis in renal cell carcinoma:Biology and implications for therapy显示文摘Although multiple advances have been made in systemic therapy for renal cell carcinoma(RCC),metastatic RCC remains incurable.In the current review,we focus on the underlying biology of RCC and plausible mechanisms of metastasis.We further outline evolving strategies to combat metastasis through adjuvant therapy.Finally,we discuss clinical patterns of metastasis in RCC and how distinct systemic therapy approaches may be considered based on the anatomic location of metastasis. | Jun Gong Manuel Caitano Maia Nazli Dizman Ameish Govindarajan Sumanta K.Pal | 2016 | Asian Journal of Urology2016，3，4： | 7 |
| 6 | Larvicidal and repellent activities of Sida acuta Burm.F.(Family:Malvaceae) against three important vector mosquitoes显示文摘Objective:To determine the larvicidal and repellent activities of Sida acuta Burm.F.(Family: Malvaceae)extract against Culex quinquefasciatus,Aedes aegypti and Anopheles stephensi. Methods:Twenty five late III instar larve of three mosquito species were exposed to various concentrations(15-90 mg/L) and were assayed in the laboratory by using the protocol of WHO 2005:the 24 h LC50 values of the Sida acuta leaf extract was determined following Probit analysis. The repellent efficacy was determined against three mosquito species at three concentrations viz.,1.0,2.5 and 5.0 mg/cm2 under the laboratory conditions.Results:Results showed varying degree of larvicidal activity of crude extract of Sida acuta against three important mosquitoes with LC50 values ranging between 38 to 48 mg/L.The crude extract had strong repellent action against three species of mosquitoes as it provided 100%protection against Anopheles stephensi for 180 min followed by Aedes aegypti(150 min) and Culex quinquefasciatus(120 min).Conclusions: From the results it can be concluded the crude extract of Sida acuta was an excellent potential for controlling Culex quinquefasciatus,Aedes aegypti and Anopleles stephensi mosquitoes. | Marimuthu Govindarajan | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，9： | 7 |
| 7 | Evaluation of Andrographis paniculata Burm.f.(Family.Acanthaceae) extracts against Culex quinquefasciatus(Say.) and Aedes aegypti(Linn.)(Diptera:Culicidae)显示文摘Objective:To investigate the larvicidal and ovicidal efficacy of different extracts of Andrographis paniculata(A.paniculata) against Culex quinquefasciatus(Cx.quinquefasciatus) Say and Aedes aegypti(Ae.aegypti ) L(Diptera:Culicidae).Methods:Larvicidal efficacy of the crude leaf extracts of A.paniculata with five different solvents like benzene,hexane,ethyl acetate, methanol and chloroform was tested against the early third instar larvae of Cx.quinquefasciatus and Ae.aegypti.The ovicidal activity was determined against two mosquito species to various concentrations ranging from 50-300 ppm under the laboratory conditions.Results:The benzene, hexane,ethyl acetate,methanol and chloroform leaf extract of A.paniculata was found to be more effective against Cx.quinquefasciatus than Ae.aegypti.The LC50 values were 112.19,137.48, 118.67,102.05,91.20 ppm and 119.58,146.34,124.24,110.12,99.54 ppm respectively.Among five tested solvent,methanol and ethyl acetate crude extract was found to be most effective for ovicidal activity against two mosquito species.The extract of methanol and ethyl acetate exerted 100%mortality at 200 ppm against Cx.quinquefasciatus and at 250 ppm against Ae.aegypti. Conclusions:From the results it can be concluded the crude extract of A.paniculata was a potential for controlling Cx.quinquefasciatus and Ae.aegypti mosquitoes. | Marimuthu Govindarajan | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，3： | 6 |
| 8 | Larvicidal and repellent properties of some essential oils against Culex tritaeniorhynchus Giles and Anopheles subpictus Grassi(Diptera:Culicidae)显示文摘Objective:To investigate the larvicidal and repellent properties of essential oils from various parts of four plant species Cymbopogan citrates,Cinnamomum zeylanicum,Rosmarinus of ficinalis and Zingiber of ficinale against Culex tritaeniorhynchus(Cx.tritaeniorhynchus) and Anopheles subpictus(An.subpktus).Methods:Essential oils were obtained by hydro-distillation method.The mosquitoes were reared in the vector control laboratory and twenty five late third ins tar larvae of Cx.tritaeniorhynchus and An.subpictus were exposed to based on the wide range and narrow range test,essential oil tested at various concentrations ranging from 25 to 250 ppm.The larval mortality was observed after 24 h under the laboratory conditions.The repellent efficacy was determined against two mosquito species at three concentrations viz., 1.0,2.5 and 5.0 mg/cm2 under laboratory conditions.Results:Results showed all the four plant essential oil produced significant larval mortality against two mosquito species.However,the highest larvicidal activity was observed in the essential oil from Zingiber of ficinale against Cx. tritaeniorhynchus and An.subpktus with the LC50 and LC90 values as 98.83,57.98 ppm and 186.55, 104.23 ppm,respectively.All the four essential oil shows significant repellency against Cx. tritaeniorhynchus than An.subpktus.Among four essential oil tested the highest repellency was observed in Zingiber of ficinale,a higher concentration of 5.0 mg/cm2 provided 100%protection up to 150 and 180 min against Cx.tritaeniorhynchus and An.subpktus,respectively.Conclusions: In this work,it can be concluded that four essential oils which were distilled from Cymbopogan citrates,Cinnamomum zeylanicum,Rosmarinus of ficinalis and Zingiber of ficinale showed promising larvicidal and repellent agent against Cx.tritaeniorhynchus and An.subpktus. | Marimuthu Govindarajan | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，2： | 5 |
| 9 | Mosquito adulticidal and repellent activities of botanical extracts against malarial vector,Anopheles stephensi Liston(Diptera:Culicidae)显示文摘To determine the adulticidal and repellent activities of different solvent leaf extracts of Eclipta alba(E.alba) and Andrographis paniculata(A.paniculata) against malarial vector, Anopheles stephensi(An.stephensi)Mathods:Adultieidal efficacy of the crude leaf extracts of E.alba and.1.paniculata with five different solvents like benzene,hexane.ethyl acetate. methanol and chloroform was tested against the five to six dav old adult female mosquitoes of An.stephensi.The adult mortality was observed after 24 h under the laboratory conditions.The repellent efficacy was determined against An,stephensi mosquito species at three concentrations viz.,1.0,2.5 and 5.0 mg/cm2 under laboratory conditions.Results:Among the tested solvents the maximum efficacy was observed in the methanol extract.The LC50 and LC90 values of E.alba and A.paniculata against adults of An.stephensi were 150.36.130.19 ppm and 285.22.244.16 ppm. respectively.No mortality was obsened in controls.The chi-square values were significant at P<0.05 lev el.Methanol extract of E.alba and A.paniculata was produce maximum repellency against An.stephensi.Conclusions:From the results it can be concluded the crude extract of E. nihil and A.paniculata was an excellent potential for controlling An.stephensi mosquitoes. | Marimuthu Govindarajan Rajamohan Sivakumar | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，12： | 4 |
| 10 | Biliary atresia: Where do we stand now?显示文摘The pathway from clinical suspicion to establishing the diagnosis of biliary atresia in a child with jaundice is a daunting task. However, investigations available help to point towards the correct diagnosis in reasonable time frame. Imaging by Sonography has identified several parameters which can be of utility in the diagnostic work up. Comparison of Sonography with imaging by Nuclear medicine can bring out the significant differences and also help in appropriate imaging. The battery of Biochemical tests, available currently, enable better understanding of the line-up of investigations in a given child with neonatal cholestasis. Management protocols enable standardized care with optimal outcome. The place of surgical management in biliary atresia is undisputed, although Kasai procedure and primary liver transplantation have been pitted against each other. This article functions as a platform to bring forth the various dimensions of biliary atresia. | Krishna Kumar Govindarajan | 2016 | World Journal of Hepatology2016，8，36： | 4 |
| 11 | Codon bias and heterologous protein expression显示文摘 | Claes Gustafsson Sridhar Govindarajan Jeremy Minshull | 2004 | Trends in Biotechnology2004，，7： | 4 |
| 12 | Larvicidal efficacy of Cassia fistula Linn. leaf extract against Culex tritaeniorhynchus Giles and Anopheles subpictus Grassi (Diptera:Culicidae)显示文摘 | M Govindarajan R Sivakumar M Rajeswari | 2011 | Asian Pacific Journal of Tropical Disease2011，，4： | 3 |
| 13 | Mosquito larvicidal properties of Ficus henghalensis L.(Family:Moraceae) against Culex tritaeniorhynchus Giles and Anopheles subpictus Grassi(Diptera:Culicidae)显示文摘Objective:To determine the larvicidal efficacy of different solvent leaf extract of Ficus benghalensis(F.benghalensis) against Culex tritaeniorhynchus(Cx.tritaeniorhynchus) and Anopheles subpictus(An.subpictus).Methods:Twenty five early third instar larvae of Cx. tritaeniorhynchus and An.subpictus were exposed to various concentrations and were assayed in the laboratory by using the protocol of WHO 2005.The larval mortality was observed after 24 h of treatment.Results:Among three solvent extracts tested the maximum efficacy was observed in the methanol extract.The LC50 and LC90 values of F.benghalensis against early third instar of Cx. tritaeniorhynchus and An.subpictus were 100.88.159.76 ppm and 56.66.85.84 ppm.respectively. No mortality was observed in controls.The chi-square values were significant at P<0.05 level. Conclusions:From the results it can be concluded the crude extract of F.benghalensis was an excellent potential for controlling Cx.tritaeniorhynchus and Art.subpictus mosquito larvae. | M Govindarajan R Sivakumar A Amsath S Niraimathi | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，7： | 3 |
| 14 | The essential oil of Zingiber officinalis Linn (Zingiberaceae) as a mosquito larvicidal and repellent agent against the filarial vector Culex quinquefasciatus Say (Diptera: Culicidae)显示文摘 | Thambusamy Pushpanathan Arulsamy Jebanesan Marimuthu Govindarajan | 2008 | Parasitology Research2008，，6： | 2 |
| 15 | A brief review on experimental fluorosis显示文摘 | Ekambaram Perumal Vanaja Paul Vimal Govindarajan Lakshmikanthan Panneerselvam | 2013 | Toxicology Letters2013，，： | 2 |
| 16 | Reactive oxygen-induced carcinogenesis causes hypermethylation of p16(Ink4a) and activation of MAP kinase显示文摘 | Govindarajan B Klafter R Miller MS | 2002 | Mol Med2002，8，1： | 2 |
| 17 | Selectivity switch in transformation of CO2 from ethanol to methanol on Cu embedded in the defect carbon显示文摘The copper-based catalysts have been generally regarded as high-performance catalysts for CO_2 hydrogenation toward methanol,while the production of ethanol via C–C coupling on the copper-based catalysts is still challenging.Herein,we report a new catalyst where Cu nanoparticles are embedded in the carbon support with abundant defect sites,achieving a high selectivity for ethanol in the CO_2 hydrogenation.The experiments coupled with the theoretical studies show a clear map where carbon defects serve as anchor sites that can stabilize interfacial copper species,and interfacial Cu sites with low coordination numbers can adsorb two C_1 species and later convert them to a C_2 species via a hydrogenation-induced coupling reaction.Further adjacent Cu atoms of interfacial Cu sites can facilitate OH reduction reactions via the Cu–Cu bridge adsorption to assist the formation of ethanol.Especially,those specific active sites easily disappear in the reducing conditions and during the reaction,the major product can transform from ethanol to methanol. | Shuohao Li Govindarajan Saranya Mingyang Chen Yan Zhu | 2020 | Science China Chemistry2020，63，5： | 2 |
| 18 | Larvicidal and ovicidal activity of Cassia fistula Linn. leaf extract against filarial and malarial vector mosquitoes显示文摘 | M. Govindarajan A. Jebanesan T. Pushpanathan | 2008 | Parasitology Research2008，，2： | 2 |
| 19 | Studies on effect of Acalypha indica L. (Euphorbiaceae) leaf extracts on the malarial vector, Anopheles stephensi Liston (Diptera:Culicidae)显示文摘 | M. Govindarajan A. Jebanesan T. Pushpanathan K. Samidurai | 2008 | Parasitology Research2008，，3： | 2 |
| 20 | Percutaneous Irreversible Electroporation for Downstaging and Control of Unresectable Pancreatic Adenocarcinoma显示文摘 | Govindarajan Narayanan Peter J. Hosein Geetika Arora Katuzka J. Barbery Tatiana Froud Alan S. Livingstone Dido Franceschi Caio M. Rocha Lima Jose Yrizarry | 2012 | Journal of Vascular and Interventional Radiology2012，，12： | 2 |
您所在的机构暂未开通此部分的功能，请联系管理员