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| 1 | Pattern of latest tectonic motion and its dynamics for active blocks in Sichuan-Yunnan region, China显示文摘Based on the concept of 'active blocks' and spatial distribution of historical earthquakes with surface ruptures as well as major and subordinate active faults. The Sichuan-Yunnan region can be divided into four first-order blocks. They are the Markam block (I), the Sichuan-Yunnan rhombic block (II), Baoshan-Pu'er block (III), and Mizhina-Ximeng block (IV). Cut by sub-ordinate NE-trending active faults, the Sichuan-Yunnan rhombic block (II) can be further divided into two sub-blocks: the northwestern Sichuan sub-block (II1) and the middle Yunnan sub-block (II2), while the Baoshan- Pu'er block (III) can be further divided into three sub-blocks: Baoshan sub-block (III1), Jinggu sub-block (III2), and Mengla sub-block (III3). A quantitative study of offset landforms is carried out and the basic types of active faults and their long-term slip rates along the major boundaries of active blocks of different orders in the Sichuan-Yunnan region are determined, through slip vector analysis, the motion states of the active blocks are clarified and the deformation coordination on the block margins is discussed. It is suggested that the tectonic motion of the blocks in this region is a complex or superimposition of three basic types of motions: southeastward sliding, rotating on vertical axis, and uplifting. The Markam block (I), the northwestern Sichuan sub-block (II1), and middle Yunnan sub-block (II2) have a southeastward horizontal sliding rate of 1-5 mm/a, clockwise rotating angular rate of 1.4-4(/Ma, and uplifting rate of about 1 mm/a. The Baoshan-Pu'er (III) and Mizhina-Ximeng (IV) blocks have also been extensively clockwise rotated. This pattern of motion is a strain response to the collision between the Indian and Eurasian plates and the localized deformation and differential slip on the block margins associated with the northward motion of the Indian Plate. Because a set of transverse thrusts between the blocks absorbs and transforms some components of eastward or southeastward sliding motion, the eastward escape or extrusion of the Tibetan Plateau is limited as 'imbricated thrusting transformation-limited extrusion model'. | XU Xiwei (徐锡伟) WEN Xueze (闻学泽) ZHENG Rongzhang (郑荣章) MA Wentao (马文涛) SONG Fangming (宋方敏) YU Guihua (于贵华) | 2003 | Science China Earth Sciences2003，46，z2： | 127 |
| 2 | Discovery of the Longriba Fault Zone in Eastern Bayan Har Block, China and its tectonic implication显示文摘Re-measured GPS data have recently revealed that a broad NE trending dextral shear zone exists in the eastern Bayan Har block about 200 km northwest of the Longmenshan thrust on the eastern margin of the Qinghai-Tibet Plateau. The strain rate along this shear zone may reach up to 4-6 mm/a. Our interpretation of satellite images and field observations indicate that this dextral shear zone corresponds to a newly generated NE trending Longriba fault zone that has been ignored before. The northeast segment of the Longriba fault zone consists of two subparallel N54°±5°E trending branch faults about 30 km apart, and late Quaternary offset landforms are well developed along the strands of these two branch faults. The northern branch fault, the Longriqu fault, has relatively large reverse component, while the southern branch fault, the Maoergai fault, is a pure right-lateral strike slip fault. According to vector synthesizing principle, the average right-lateral strike slip rate along the Longriba fault zone in the late Quaternary is calculated to be 5.4±2.0 mm/a, the vertical slip rate to be 0.7 mm/a, and the rate of crustal shortening to be 0.55 mm/a. The discovery of the Longriba fault zone may provide a new insight into the tectonics and dynamics of the eastern margin of the Qinghai-Tibet Plateau. Taken the Longriba fault zone as a boundary, the Bayan Har block is divided into two sub-blocks: the Ahba sub-block in the west and the Longmenshan sub-block in the east. The shortening and uplifting of the Longmenshan sub-block as a whole reflects that both the Longmenshan thrust and Longriba fault zone are subordinated to a back propagated nappe tectonic system that was formed during the southeastward motion of the Bayan Har block owing to intense resistance of the South China block. This nappe tectonic system has become a boundary tectonic type of an active block supporting crustal deformation along the eastern margin of the Qinghai-Tibet Plateau from late Cenozoic till now. The Longriba fault zone is just an active fault zone newly-generated in late Quaternary along this tectonic system. | XU XiWei WEN XueZe CHEN GuiHua YU GuiHua | 2008 | Science China Earth Sciences2008，51，9： | 46 |
| 3 | Parameters of Coseismic Reverse- and Oblique-Slip Surface Ruptures of the 2008 Wenchuan Earthquake,Eastern Tibetan Plateau显示文摘在 2008 年 5 月 12 日, M w 7.9 Wenchuan 地震破裂了同时,, Longmenshan 的中间的片断插入了的 Beichuan, Pengguan 和 Xiaoyudong 差错在西藏的高原的东方边缘系上带子。领域调查抑制与 Wenchuan 地震有关的表面破裂模式,长度和偏移量。Beichuan 差错有趋势 NE 有 240 km 的全部的长度的权利侧面的反向的破裂。重估产出 6.5 ±的最大的垂直偏移量 0.5 m 和 4.9 ±的最大的权利侧面的偏移量为它的北片断的 0.5 m,它最大的偏移量被发现;最大的垂直偏移量是 6.2 ±为它的南部的片断的 0.5 m。Pengguan 差错有趋势 NE 纯反向的破裂与大约 3.5 m 的最大的垂直偏移量长的大约 72 km。Xiaoyudong 差错有在 Beichuan 和 Pengguan 之间长的大约 7 km 指责的 NW 惹人注目的左侧面的反向的破裂,与 3.4 m 的最大的垂直偏移量和 3.5 m 的左侧面的偏移量。多重 co 地震的表面破裂的这个模式在之中最近的大地震和礼品最复杂大得多的危险比如果他们个别地破裂了。破裂长度最长因为反向的指责事件曾经报导了。 | XU Xiwei YU Guihua CHEN Guihua RAN Yongkang LI Chenxia CHEN Yuegau CHANG Chungpai | 2009 | Acta Geologica Sinica(English Edition)2009，83，4： | 30 |
| 4 | Conductive polymers for stretchable supercapacitors显示文摘Stretchable energy storage devices,maintaining the capability of steady operation under large mechanical strain,have become increasing more important with the development of stretchable electronic devices.Stretchable supercapacitors(SSCs),with high power density,modest energy density,and superior mechanical properties are regarded as one of the most promising power supplies to stretchable electronic devices.Conductive polymers,such as polyaniline(PANI),polypyrrole(PPy),polythiophene(PTh)and poly(3,4-ehtylenedioxythiophene)(PEDOT),are among the well-studied electroactive materials for the construction of SSCs because of their high specific theoretical capacity,excellent electrochemical activity,light weight,and high flexibility.Much effort has been devoted to developing stretchable,conductive polymer-based SSCs with different device structures,such as sandwich-type and fiber-shaped type SSCs.This review summarizes the material and structural design for con ductive polymer-based SSCs and discusses the challenge and importa nt di recti ons in this emergi ng field. | Yaqun Wang Yu Ding Xuelin Guo Guihua Yu | 2019 | Nano Research2019，12，9： | 16 |
| 5 | Evaluating efficacy of screening for upper gastrointestinal cancer in China:a study protocol for a randomized controlled trial显示文摘Objective: To evaluate the efficacy and feasibility of screening procedure for upper gastrointestinal cancer in both high-risk and non-high-risk areas in China.Setting: Seven cities/counties, representing three economical-geographical regions(Eastern, Central and Western) in China, were selected as screening centers: three in high-risk areas and four in non-high-risk areas.Participants: Villages/communities in these seven centers regarded as clusters were randomly assigned to either intervention group(screening by endoscopic examination) or control group(with normal community care) in a 1:1ratio stratified by each center. Eligible participants are local residents aged 40–69 years in the selected villages/communities with no history of cancer or endoscopic examination in the latest 3 years who are mentally and physically competent. Those who are not willing to take endoscopic examination or are unwilling to sign the consent form are excluded from the study. Totally 140,000 participants will be enrolled.Interventions: In high-risk areas of upper gastrointestinal cancer, all subjects in screening group will be screened by endoscopy. In non-high-risk areas, 30% of the subjects in screening group, identified through a survey,will be screened by endoscopy.Primary and secondary outcome measures: The primary outcome is the mortality caused by upper gastrointestinal cancer. The secondary outcomes include detection rate, incidence rate, survival rate, and clinical stage distribution. Additional data on quality of life and cost-effectiveness will also be collected to answer important questions regarding screening effects.Conclusions: Screening strategy evaluated in those areas with positive findings may be promoted nationally and applied to the majority of Chinese people. On the other hand, negative findings will provide scientific evidence for abandoning a test and shifting resources elsewhere.Trial registration: The study has been registered with the Protocol Registration System in Chinese Clinical Trial Registry. | wanqing chen hongmei zeng ru chen ruyi xia zhixun yang changfa xia rongshou zheng wenqiang wei guihua zhuang xueqin yu jie he | 2017 | Chinese Journal of Cancer Research2017，29，4： | 11 |
| 6 | High-Resolution Genome-wide Association Study Identifies Genomic Regions and Candidate Genes for Important Agronomic Traits in Wheat显示文摘Wheat(Triticum aestivum)is a major staple food crop worldwide.Genetic dissection of important agronomic traits is essential for continuous improvement of wheat yield to meet the demand of the world's growing population.We conducted a large-scale genome-wide association study(GWAS)using a panel of 768 wheat cultivars that were genotyped with 327609 single-nucleotide polymorphisms generated by genotyping-by-sequencing and detected 395 quantitative trait loci(QTLs)for 12 traits under 7 environments.Among them,273 QTLs were delimited to≤1.0-Mb intervals and 7 of them are either known genes(Rht-D,Vrn-B1,and Vrn-D1)that have been cloned or known QTLs(TaGA2ox8,APO1,TaSus1-7B,and Rht12)that were previously mapped.Eight putative candidate genes were identified for three QTLs that enhance spike seed setting and grain size using gene expression data and were validated in three bi-parental populations.Protein sequence analysis identified 33 putative wheat orthologs that have high identity with rice genes in QTLs affecting similar traits.Large r^2 values for additive effects observed among the QTLs for most traits indicated that the phenotypes of these identified QTLs were highly predictable.Results from this study demonstrated that significantly increasing GWAS population size and marker density greatly improves detection and identification of candidate genes underlying a QTL,solidifying the foundation for large-scale QTL fine mapping,candidate gene validation,and developing functional markers for genomics-based breeding in wheat. | Yunlong Pang Chunxia Liu Danfeng Wang Paul St.Amand Amy Bernardo Wenhui Li Fang He Linzhi Li Liming Wang Xiufang Yuan Lei Dong Yu Su Huirui Zhang Meng Zhao Yunlong Liangi Hongze Jia Xitong Shen Yue Lu Hongming Jiang Yuye Wu Anfei Li Honggang Wang Lingrang Kong Guihua Bai Shubing Liu | 2020 | Molecular Plant2020，13，9： | 8 |
| 7 | Landslides and Slope Fissures Triggered by the April 14,2010 Yushu Earthquake, China显示文摘On April 14, 2010 at 07:49 (Beijing time), a catastrophic earthquake with MS7.1 occurred at the central Qinghai-Tibetan Plateau. The epicenter was located at Yushu county, Qinghai Province, China. A total of 2036 landslides were determined from visual interpretation of aerial photographs and high resolution remote sensing images, and verified by selected field investigations. These landslides covered a total area of about 1.194km2. Characteristics and failure mechanisms of these landslides are listed in this paper, including the fact that the spatial distribution of these landslides is controlled by co-seismic main surface fault ruptures. Most of the landslides were small scale, causing rather less hazards, and often occurring close to each other. The landslides were of various types, including mainly disrupted landslides and rock falls in shallows and also deep-seated landslides, liquefaction induced landslides, and compound landslides. In addition to strong ground shaking, which is the direct landslide triggering factor, geological, topographical, and human activity also have impact on the occurrence of earthquake triggered landslides. In this paper, five types of failure mechanisms related to the landslides are presented, namely, the excavated toes of slopes accompanied by strong ground shaking; surface water infiltration accompanied by strong ground shaking; co-seismic fault slipping accompanied by strong ground shaking; only strong ground shaking; and delayed occurrence of landslides due to snow melt or rainfall infiltration at sites where slopes were weakened by co-seismic ground shaking. Besides the main co-seismic surface ruptures, slope fissures were also delineated from visual interpretation of aerial photographs in high resolution. A total of 4814 slope fissures, with a total length up to 77.1km, were finally mapped. These slope fissures are mainly distributed on the slopes located at the southeastern end of the main co-seismic surface rupture zone, an area subject to strong compression during the earthquake. | Xu Chong Xu Xiwei Yu Guihua | 2013 | Earthquake Research in China2013，27，1： | 4 |
| 8 | A mini review on two-dimensional nanomaterial assembly显示文摘Two-dimensional(2D)nanomaterials have attracted a great deal of attention since the discovery of graphene in 2004,due to their intriguing physicochemical properties and wide-ranging applications in catalysis,energy-related devices,electronics and optoelectronics.To maximize the potential of 2D nanomaterials for their technological applications,controlled assembly of 2D nanobulding blocks into integrated systems is critically needed.This mini review summarizes the reported strategies of 2D materials-based assembly into integrated functional nanostructures,from in-situ assembly method to post-synthesis assembly.The applications of 2D assembled integrated structures are also covered,especially in the areas of energy,electronics and sensing,and we conclude with discussion on the remaining challenges and potential directions in this emerging field. | Zhiwei Fang Qiyu Xing Desiree Fernandez Xiao Zhang Guihua Yu | 2020 | Nano Research2020，13，5： | 4 |
| 9 | Engineering Hydrogels for Efficient Solar Desalination and Water Purification显示文摘CONSPECTUS:Safe and adequate water is a global challenge due to the growing population and pollution in the wake of natural disasters.Access to clean water is a cornerstone for the further development of our modern society.Solar-powered desalination and water purification have attracted much research attention due to the high solar-to-thermal conversion efficiency and ease of implementation in multiple scales,from compact,stand-alone devices for individual households to large,centralized dimensions for communities.Nevertheless,the generation of water vapor at low temperatures below the boiling point is usually a slow process under natural sunlight.The production rate of clean water relies on the efficiencies of solar energy conversion and utilization,which can be enhanced in two directions:systems optimization and materials innovation.Starting from bottom heating and volumetric heating,interfacial evaporation has been adopted recently to systematically reduce energy loss by localizing heat near the evaporation surface using photothermal materials.Meanwhile,carbonaceous materials,narrow bandgap semiconductors,and polymers with different structures were designed to achieve thermal management and water transport.In this Account,we highlight the recent progress of hydrogels as a highly tunable material platform for solar-powered desalination and water purification.We begin by introducing how gelation chemistry endows hydrogels with desirable properties and multiscale tunability from molecular to macroscopic levels.Then,we review three major strategies to promote efficient solar-to-vapor conversion in terms of reducing water evaporation enthalpy,optimizing heat distribution,and tailoring the evaporation surface.First,by selecting polymeric backbones with hydratable functional groups,the water state in hydrogels can be regulated to facilitate intermediate water,which has a lower evaporation enthalpy compared to that of the bulk water.This polymer−water interaction can be further tuned during synthesis and post-treatment.Second,light-absorbing additives within hydrogels should not only convert solar energy to heat effectively but also confine the heat near the evaporative surfaces.Third,since water molecules are encapsulated in the polymer network of hydrogels,the surface of the hydrogel becomes the evaporation front of liquid water.Hence,tailoring the surface topography and wettability of hydrogels has important effects on the evaporation rate.Next,we discuss key functions that endow hydrogel evaporators with excellent desalination and purification performances,including anti-salt-fouling property for stable and long-term desalination,as well as easy integration of functional materials to remove other contaminants,such as heavy metal ions and organic dyes,for greater distillate quality.Last,existing challenges and future opportunities in both fundamental studies and practical implementation of the hydrogel-based solar water purification systems are discussed. | Youhong Guo Guihua Yu | 2021 | Accounts of Materials Research2021，2，5： | 4 |
| 10 | Chemically Binding Scaffolded Anodes with 3D Graphene Architectures Realizing Fast and Stable Lithium Storage显示文摘Tree-dimensional(3D)graphene has emerged as an ideal platform to hybridize with electrochemically active materials for improved performances.However,for lithium storage,current anodic guests ofen exist in the form of nanoparticles,physically attached to graphene hosts,and therefore tend to detach from graphene matrices and aggregate into large congeries,causing considerable capacity fading upon repeated cycling.Herein,we develop a facile double-network hydrogel-enabled methodology for chemically binding anodic scafolds with 3D graphene architectures.Taking tin-based alloy anodes as an example,the doublenetwork hydrogel,containing interpenetrated cyano-bridged coordination polymer hydrogel and graphene oxide hydrogel,is directly converted to a physical-intertwined and chemical-bonded Sn−Ni alloy scafold and graphene architecture(Sn−Ni/G)dual framework.Te unique dual framework structure,with remarkable structural stability and charge-transport capability,enables the Sn−Ni/G anode to exhibit long-term cyclic life(701 mA h g^(−1) afer 200 cycles at 0.1 A g^(−1))and high rate performance(497 and 390 mA h g^(−1) at 1 and 2 A g^(−1),respectively).Tis work provides a new perspective towards chemically binding scafolded low-cost electrode and electrocatalyst materials with 3D graphene architectures for boosting energy storage and conversion. | Ping Wu Zhiwei Fang Anping Zhang Xiao Zhang Yawen Tang Yiming Zhou Guihua Yu | 2019 | Research2019，，1： | 4 |
| 11 | Synthesis and Tumor Cytotoxicity of Novel N-Substituted Glucosamine-bearing Oleanolic Acid Derivatives显示文摘 | REN Li LIU Yang YU Guihua GAO Yuan LIU Xin WANG Bo DENG Xiaonan CHENG Maosheng | 2014 | Chemical Research in Chinese Universities2014，30，4： | 3 |
| 12 | Impact of warm mesoscale eddy on tropical cyclone intensity显示文摘The spatial-temporal patterns of tropical cyclone(TC) intensity changes caused by the warm ocean mesoscale eddy(WOME) distribution are evaluated using two sets of idealized numerical experiments. The results show that the TC was intensified and weakened when a WOME was close to and far away from the TC center, respectively.The area where the WOME enhanced(weakened) TC intensity is called the inner(outer) area in this study.Amplitudes of the enhancement and weakening caused by the WOME in the inner and outer area decreased and increased over time, while the ranges of the inner and outer area diminished and expanded, respectively. The WOME in the inner area strengthened the secondary circulation of the TC, increased heat fluxes, strengthened the symmetry, and weakened the outer spiral rainband, which enhanced TC intensity. The effect was opposite if the WOME was in the outer area, and it weakened the TC intensity. The idealized simulation employed a stationary TC, and thus the results may only be applied to TCs with slow propagation. These findings can improve our understanding of the interactions between TC and the WOME and are helpful for improving TC intensity forecasting by considering the effect of the WOME in the outer areas. | Jia Sun Guihua Wang Xuejun Xiong Zhenli Hui Xiaomin Hu Zheng Ling Long Yu Guangbing Yang Yanliang Guo Xia Ju Liang Chen | 2020 | Acta Oceanologica Sinica2020，39，8： | 3 |
| 13 | Relative manifold based semi-supervised dimensionality reduction显示文摘 | Xianfa CAI Guihua WEN Jia WEI Zhiwen YU | 2014 | Frontiers of Computer Science2014，8，6： | 3 |
| 14 | C.elegans-based screen identifies lysosome-damaging alkaloids that induce STAT3-dependent lysosomal cell death显示文摘Lysosomes are degradation and signaling centers within the cell,and their dysfunction impairs a wide variety of cellular processes.To understand the cellular effect of lysosome damage,we screened natural smallmolecule compounds that induce iysosomal abnormality using Caenorhabditis elegans (C.elegans)as a model system.A group of vobasinyl-ibogan type bisindole alkaloids (ervachinines A-D)were identified that caused lysosome enlargement in C.elegans macrophage-like cells.Intriguingly,these compounds triggered cell death in the germ line independently of the canonical apoptosis pathway.In mammalian cells, ervachinines A-D induced lysosomal enlargement and damage,leading to leakage of cathepsin proteases, inhibition of autophagosome degradation and necrotic cell death.Further analysis revealed that this ervachinine-induced lysosome damage and lysosomal cell death depended on STAT3 signaling,but not RIP1 or RIP3 signaling.These findings suggest that lysosomedamaging compounds are promising reagents for dissecting signaling mechanisms underlying lysosome homeostasis and lysosome-related human disorders. | Yang Li Yu Zhang Qiwen Gan Meng Xu Xiao Ding Guihua Tang Jingjing Liang Kai Liu Xuezhao Liu Xin Wang Lingli Guo Zhiyang Gao Xiaojiang Hao Chonglin Yang | 2018 | Protein & Cell2018，9，12： | 2 |
| 15 | Cellular prion protein released on exosomes from macrophages binds to Hsp70显示文摘Prion 疾病是传染、致命的 neurodegenerative 混乱。变换成 prion 蛋白质(PrPSc ) 的错误褶层 isoform 的细胞的 prion 蛋白质(PrPC ) 为 prion 疾病感染负责。免疫系统在从圆周便于 prion 感染的传播到中央神经系统起一个重要作用。巨噬细胞被认为与 PrPSc 的交通和复制联系了。那么,在巨噬细胞理解 PrPC trafficking 是重要的为 PrPSc 探索运输机制。这里,我们从 Ana-1 巨噬细胞房间线的文化媒介孤立 exosomes 并且由西方的弄污, immunoelectron 显微镜学,和 co-immunoprecipitation 在分泌 exosomes 由 exosomes 和和 Hsp70 的 PrPC 的相互作用调查了 PrPC trafficked。结果证明从巨噬细胞的文化媒介的孤立的泡被 exosomes 和讨厌的人 PrPC 描绘。并且 PrPC 在细胞内部的环境两个都跳了到 Hsp70 并且分泌了 exosomes。相反, PrPC 没与 exosomes, Tag101 和 Flotillin-1 的标记蛋白质有相互作用。这些结果建议在细胞外的空间在场的 PrPC 可能是通过从巨噬细胞的分泌 exosomes 的 externalized,并且 Hsp70 可以在经由分泌 exosomes 释放的 PrPC 的过程起作用。 | Guihua Wang Xiangmei Zhou Yu Bai Zhongqiu Zhang Deming Zhao | 2010 | Acta Biochimica et Biophysica Sinica2010，42，5： | 2 |
| 16 | Vertically aligned two-dimensional materials-based thick electrodes for scalable energy storage systems显示文摘Together with the blooming of portable smart devices and electric vehicles in the last decade,electrochemical energy storage(EES)devices capable of high-energy and high-power storage are urgently needed.Two-dimensional(2D)materials,benefiting from the short solid-state diffusion distance,are well recognized to possess excellent electrochemical performance.However,liquid diffusion,the rate-determining process in thick electrodes,is notably slow in 2D materials-based electrodes stemming from their stacking during electrode processing,which considerably limits their applications for high energy storage.To fully exploit intrinsic advantages of 2D materials for scalable energy storage devices,this review summarizes several important strategies,ranging from assembly to template methods,to fabricate vertically aligned 2D materials-based electrodes.We further discuss the advantages and challenges of these methods in terms of key features of thick electrodes and illustrate the design principles for high-energy/power devices. | Zhengyu Ju Xiao Zhang Jingyi Wu Guihua Yu | 2021 | Nano Research2021，14，10： | 1 |
| 17 | Improving the perform- ance of lithium-sulfur batteries by conductive polymer coating 显示文摘 | Yang Yuan Yu Guihua Cha J J | 2011 | ACS Nano2011，11，： | 1 |
| 18 | Parametric study and field synergy principle analysis of H-type finned tube bank with 10 rows 显示文摘 | Jin Yu Tang Guihua He Yaling Tao Wenquan | 2013 | International Journal of Heat and Mass Transfer2013，60，1： | 1 |
| 19 | Sustainable electrical energy storage through the ferrocene/ferrocenium redox reaction in aprotic electrolyte显示文摘 | Zhao Yu Ding Yu Song Jie Li Gang Dong Guangbin Goodenough John B Yu Guihua | 2014 | Angewandte Chemie International Edition2014，53，11： | 1 |
| 20 | A reversible Br2/Br-redox couple in the aqueous phase as a high-performance catholyte for alkali-ion batteries显示文摘 | Zhao Yu Ding Yu Song Jie Peng Lele Goodenough John B Yu Guihua | 2014 | Energy&Environmental Science2014，7，6： | 1 |
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