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| 1 | Insight-HXMT observations of the first binary neutron star merger GW170817显示文摘Finding the electromagnetic(EM) counterpart of binary compact star merger, especially the binary neutron star(BNS) merger,is critically important for gravitational wave(GW) astronomy, cosmology and fundamental physics. On Aug. 17, 2017,Advanced LIGO and Fermi/GBM independently triggered the first BNS merger, GW170817, and its high energy EM counterpart,GRB 170817 A, respectively, resulting in a global observation campaign covering gamma-ray, X-ray, UV, optical, IR, radio as well as neutrinos. The High Energy X-ray telescope(HE) onboard Insight-HXMT(Hard X-ray Modulation Telescope) is the unique high-energy gamma-ray telescope that monitored the entire GW localization area and especially the optical counterpart(SSS17 a/AT2017 gfo) with very large collection area(~1000 cm^2) and microsecond time resolution in 0.2-5 MeV. In addition,Insight-HXMT quickly implemented a Target of Opportunity(ToO) observation to scan the GW localization area for potential X-ray emission from the GW source. Although Insight-HXMT did not detect any significant high energy(0.2-5 MeV) radiation from GW170817, its observation helped to confirm the unexpected weak and soft nature of GRB 170817 A. Meanwhile,Insight-HXMT/HE provides one of the most stringent constraints(~10^(-7) to 10^(-6) erg/cm^2/s) for both GRB170817 A and any other possible precursor or extended emissions in 0.2-5 MeV, which help us to better understand the properties of EM radiation from this BNS merger. Therefore the observation of Insight-HXMT constitutes an important chapter in the full context of multi-wavelength and multi-messenger observation of this historical GW event. | TiPei Li ShaoLin Xiong ShuangNan Zhang FangJun Lu LiMing Song XueLei Cao Zhi Chang Gang Chen Li Chen TianXiang Chen Yong Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong YuanYuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao CongZhan Liu GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge OU JinLu Qu Na Sai Liang Sun Yin Tan Lian Tao WenHui Tao YouLi Tuo GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BoBing WU Mei Wu GuangCheng Xiao He Xu YuPeng Xu LinLi Yan JiaWei Yang Sheng Yang YanJi Yang AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang Shu Zhang Tong Zhang Wei Zhang WanChang Zhang WenZhao Zhang Yi Zhang Yue Zhang YiFei Zhang YongJie Zhang Zhao Zhang ZiLiang Zhang HaiSheng Zhao JianLing Zhao XiaoFan Zhao ShiJie Zheng Yue Zhu YuXuan Zhu ChangLin Zou | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，3： | 12 |
| 2 | Development of Human in vitro Brain-blood Barrier Model from Induced Pluripotent Stem Cell-derived Endothelial Cells to Predict the in vivo Permeability of Drugs显示文摘An in vitro blood-brain barrier(BBB) model is critical for enabling rapid screening of the BBB permeability of the drugs targeting on the central nervous system.Though many models have been developed, their reproducibility and renewability remain a challenge. Furthermore, drug transport data from many of the models do not correlate well with the data for in vivo BBB drug transport.Induced-pluripotent stem cell(i PSC) technology provides reproducible cell resources for in vitro BBB modeling.Here, we generated a human in vitro BBB model by differentiating the human i PSC(hi PSC) line GM25256 into brain endothelial-type cells. The model displayed BBB characteristics including tight junction proteins(ZO-1,claudin-5, and occludin) and endothelial markers(von Willebrand factor and Ulex), as well as high transendothelial electrical resistance(TEER)(1560 X.cm2±230 X.cm2) and c-GTPase activity. Co-culture with primary rat astrocytes significantly increased the TEER of the model(2970 X.cm2 to 4185 X.cm2). RNAseq analysis confirmed the expression of key BBB-related genes in the hi PSC-derived endothelial cells in comparison with primary human brain microvascular endothelial cells,including P-glycoprotein(Pgp) and breast cancer resistant protein(BCRP). Drug transport assays for nine CNS compounds showed that the permeability of non-Pgp/BCRP and Pgp/BCRP substrates across the model was strongly correlated with rodent in situ brain perfusion data for these compounds(R2= 0.982 and R2= 0.9973,respectively), demonstrating the functionality of the drug transporters in the model. Thus, this model may be used to rapidly screen CNS compounds, to predict the in vivo BBB permeability of these compounds and to study the biology of the BBB. | Yuan Li Xueying Sun Houfu Liu Liang Huang Guofeng Meng Yu Ding Wenji Su Jiaqi Lu Sophie Gong Georg C.Terstappen Ru Zhang Wandong Zhang | 2019 | Neuroscience Bulletin2019，35，6： | 3 |
| 3 | One step method of structure engineering porous graphitic carbon nitride for efficient visible-light photocatalytic reduction of Cr(Ⅵ)显示文摘Porous g-C_(3)N_(4)nanosheets(PCN)were prepared by the nickel-assisted one-step thermal polymerization method.Hydrogen(H2)which was produced by the reaction between nickel(Ni)foam and ammonia(NH3)defined the structure and properties of PCN.During the formation of PCN,the participation of H2 not only enhanced the spacing between layers but also boosted the specific surface area that more active sites were exposed.Additionally,H2 promoted pores formation in the nanosheets,which was beneficial to the transfer of photons through lamellar structure and improved the absorption efficiency of visible light.Remarkably,the obtained PCN possessed better Cr(Ⅵ)photocatalytic reduction efficiency than pure g-C_(3)N_(4).The reaction rate constant(k)of PCN(0.013 min-1)was approximately twice that of bare g-C_(3)N_(4)(0.007 min-1).Furthermore,the effects of original pH and concentration of Cr(Ⅵ)-containing solution on re moval efficiency of Cr(Ⅵ)were explored.A possible photocatalytic mecha nism was proposed based on the experiments of radical scavengers and photoelectrochemical characterizations. | Xueru Chen Yin Zhang Dashui Yuan Wu Huang Jing Ding Hui Wan Wei-Lin Dai Guofeng Guan | 2021 | Journal of Materials Science & Technology2021，，12： | 3 |
| 4 | Overview to the Hard X-ray Modulation Telescope (Insight-HXMT) Satellite显示文摘As China’s first X-ray astronomical satellite, the Hard X-ray Modulation Telescope (HXMT), which was dubbed as Insight-HXMT after the launch on June 15, 2017, is a wide-band(1-250 ke V) slat-collimator-based X-ray astronomy satellite with the capability of all-sky monitoring in 0.2-3 Me V. It was designed to perform pointing, scanning and gamma-ray burst(GRB)observations and, based on the Direct Demodulation Method (DDM), the image of the scanned sky region can be reconstructed.Here we give an overview of the mission and its progresses, including payload, core sciences, ground calibration/facility, ground segment, data archive, software, in-orbit performance, calibration, background model, observations and some preliminary results. | Shuang-Nan Zhang TiPei Li FangJun Lu LiMing Song YuPeng X u CongZhan Liu Yong Chen XueLei Cao QingCui Bu Zhi Chang Gang Chen Li Chen TianXiang Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong Yuan Yuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan Can Gungor ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge Ou JinLu Qu Na Sai RenCheng Shang GuoHong Shen Liang Sun Ying Tan Lian Tao YouLi Tuo Chen Wang ChunQin Wang GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BaiYang Wu BoBing Wu Mei Wu GuangCheng Xiao ShaoLin Xiong LinLi Yan JiaWei Yang Sheng Yang YanJi Yang QiBin Yi Bin Yuan AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang ShenYi Zhangs Shu Zhang Tong Zhang WanChang Zhang Wei Zhang WenZhao Zhang Yi Zhang YiFei Zhang YongJie Zhang Yue Zhang Zhao Zhang Zhi Zhang ZiLiang Zhang HaiSheng Zhao XiaoFan Zhao ShiJie Zheng JianFeng Zhou YuXuan Zhu Yue Zhu RenLin Zhuang | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，4： | 2 |
| 5 | Solid rocket motor propellant grain burnback simulation based on fast minimum distance function calculation and improved marching tetrahedron method显示文摘To efficiently compute arbitrary propellant grain evolution of the burning surface with uniform and non-uniform burning rate for solid rocket motor,a unified framework of burning surface regression simulation has been developed based on minimum distance function.In order to speed up the computation of the mini-mum distance between grid nodes of grain and the triangular mesh of burning surface,a fast distance querying method based on the equal size cube voxel structure was employed.An improved marching tetrahedron method based on piecewise linear approximation was carried out on second-order tetrahedral elements,achieved high-efficiency and adequate accuracy of burning surface extraction simultaneously.The cases of star grain,finocyl grain,and non-uniform tube grain were studied to verify the proposed method.The observed result indicates that the grain burnback computation method could realize the accurate simulation on unstructured tetrahedral mesh with a desirable performance on computational time. | Pengfei REN Hongbo WANG Guofeng ZHOU Jiani LI Qiang CAI Jiaquan YU Ya YUAN | 2021 | Chinese Journal of Aeronautics2021，34，4： | 2 |
| 6 | QoE-Oriented Resource Allocation for Multiuser-Multiservice Femtocell Networks显示文摘The pursuit of high data rate and assurance of quality of experience(QoE) for end users represent the main goals of future wireless communication systems.By introducing MOS(Mean Opinion Score) based assessment models for different types of applications,this paper proposed novel QoE-oriented radio resource allocation(RRA) algorithms for multiuser-multiservice femtocell networks.An optimal QoE-oriented RRA strategy is first analyzed using time-sharing method which is applicable to best effort applications.RRA algorithms based on the cross-layer architecture are then proposed for all types of applications by considering parameters extracted from different layers of networking protocols.In the proposed algorithms,a priority mechanism is employed to ensure fairness.Simulation results show that the proposed algorithms can significantly improve the overall perceived quality from the users' perspective in comparison with traditional Quality of Service(QoS)oriented algorithms. | YUAN Deyu SONG Mei TENG Yinglei MA Ding WANG Xiaojun LU Guofeng | 2015 | China Communications2015，12，10： | 2 |
| 7 | Contribution of Temperature Increase to Restrain the Transmission of COVID-19显示文摘The COVID-19 outbreak has already become a global pandemic and containing this rapid worldwide transmission is of great challenge.The impacts of temperature and humidity on the COVID-19 transmission rate are still under discussion.Here,we elucidated these relationships by utilizing two unique scenarios,repeated measurement and natural experiment,using the COVID-19 cases reported from January 23–February 21,2020,in China.The modeling results revealed that higher temperature was most strongly associated with decreased COVID-19 transmission at a lag time of 8 days.Relative humidity(RH)appeared to have only a slight effect.These findings were verified by assessing SARSCoV-2 infectivity under the relevant conditions of temperature(4C–37C)and RH(>40%).We concluded that temperature increase made an important,but not determined,contribution to restrain the COVID19 outbreak in China.It suggests that the emphasis of other effective controlling polices should be strictly implemented to restrain COVID19 transmission in cold seasons. | Mengyuan Ren Rongjuan Pei Bahabaike Jiangtulu Junxi Chen Tao Xue Guofeng Shen Xiaoru Yuan Kexin Li Changxin Lan Zhen Chen Xinwen Chen Yun Wang Xiaoqian Jia Zewu Li Audil Rashid Tippawan Prapamontol Xiuge Zhao Zhaomin Dong Yali Zhang Le Zhang Rongwei Ye Zhiwen Li Wuxiang Guan Bin Wang | 2021 | The Innovation2021，2，1： | 2 |
| 8 | Experimental study of a solar desalination system based on humidification- dehumidification process 显示文摘 | Yuan Guofeng Wang Zhifeng | 2011 | Desalination2011，277，13： | 1 |
| 9 | One-step fabrication of nitrogen-deficient carbon nitride through pyrolysis of melamine and 1,2,4-triazole for its enhanced photocatalytic degradation显示文摘The construction of defects in semiconductor photocatalysts,as a kind of modification methods,plays an indispensable role in the enhancement of the photocatalytic performance.Herein,nitrogen defects were successfully introduced into the framework of graphite carbon nitride(CN-T_(x))through thermal polymerization with melamine and 1,2,4-triazole as precursors.The existence of nitrogen defects in CN-T_(x) were confirmed to be located at the two-coordinated(N_(2c))C■N-C lattice sites,which resulted in the destruction of its planar structure and the initiation of n-π^(*)electron transition that greatly expanded the response range to visible light and improved the separation efficiency of photogenerated charge carrier.More significantly,CN-T_(x) could enhance photocatalytic water purification activity towards different kinds of pollutants.The photocatalytic rates of CN-T_(3) were estimated to be 2.54(tetracycline)and 2.31(2-hydroxynaphthalene)times higher than those of pristine g-C3N4.Furthermore,the possible photocatalytic degradation mechanism over CN-T_(x) photocatalyst was proposed by free radical trapping experiments combined with ERS characterization.This work provides an in-depth understanding of the important role of nitrogen defects in the electronic structure and chemical properties of g-C3N4 and its photocatalytic water purification performance. | Jing Ding Zongyuan Li Xueru Chen Yiwei Jiao Dashui Yuan Wei Du Hui Wan Guofeng Guan | 2021 | Green Chemical Engineering2021，2，3： | 1 |
| 10 | Experimental study of a solar desalination system based on humidification–dehumidification process显示文摘 | Guofeng Yuan Zhifeng Wang Hongyong Li Xing Li | 2011 | Desalination2011，，1： | 1 |
| 11 | Experimental study of as solar desalination system based on humidification-dehumidification proscess 显示文摘 | Yuan Guofeng Wang Zhifeng Li Hongyong | 2011 | Desalination2011，277，13： | 1 |
| 12 | Chemical compositions and reconstructed light extinction coefficients of particulate matter in a mega-city in the western Yangtze River Delta, China 显示文摘 | SHEN Guofeng XUE Miao YUAN Siyu | 2014 | Atmospheric Environment2014，83，： | 1 |
| 13 | Numerical and Experimental In- vestigation of Performance of the Liquid-Gas and Liquid Jet Pumps in Desalination Systems 显示文摘 | Yuan Guofeng Zhang Lixi | 2011 | Desalination2011，276，： | 1 |
| 14 | A new method of laser sheet imaging-based fire smoke detection 显示文摘 | Xueming Shu Hongyong Yuan Guofeng Su | 2006 | Journal of Fire Sciences2006，24，2： | 1 |
| 15 | Quantitative proteomic analysis of host responses triggered by Mycobacterium tuberculosis infection in human macrophage cells显示文摘 | Hua Li Sha Wei Yuan Fang Min Li Xia Li Zhe Li Jibin Zhang Guofeng Zhu Chuanyou Li Lijun Bi Guimin Zhang Dianbing Wang Xian-En Zhang | 2017 | Acta Biochimica et Biophysica Sinica2017，49，9： | 1 |
| 16 | In situ gas filter correlation photoacoustic co detection method for fire warning 显示文摘 | Chen Tao Su Guofeng Yuan Hongyong | 2005 | Sensors and Actuators B2005，109，2： | 1 |
| 17 | Application of 3D Visualization Technique in Tahe Oilfield显示文摘 | Yuan GuoFen Sun GuoFeng Zhang XunGuang | 2008 | Xinjiang Geology2008，18，2： | 1 |
| 18 | Experimental study of a solar desalination system based on humidification-dehumidification process显示文摘 | Yuan Guofeng Wang Zhifeng Li Hongyong | 2011 | Desalination2011，277，13： | 1 |
| 19 | In situ gas filter correlation: photoacoustic CO detection method for fire warning 显示文摘 | Chen Tao Su Guofeng Yuan Hongyong | 2005 | Sensors andAetuators B: Chemical2005，109，2： | 1 |
| 20 | Numerical and experimental investigation of performance of the liquid-gas and liquid jet pumps in desalination systems显示文摘 | YUAN Guofeng ZHANG Lixi ZHANG Hefei | 2011 | Desalination2011，276，： | 1 |
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