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1Interaction between the gut microbiome and mucosal immune system显示文摘The gut microbiota, the largest symbiotic ecosystem with the host, has been shown to play important roles in maintaining intestinal homeostasis. Dysbiosis of the gut microbiome is caused by the imbalance between the commensal and pathogenic microbiomes. The commensal microbiome regulates the maturation of the mucosal immune system, while the pathogenic microbiome causes immunity dysfunction, resulting in disease development.The gut mucosal immune system, which consists of lymph nodes, lamina propria and epithelial cells, constitutes a protective barrier for the integrity of the intestinal tract. The composition of the gut microbiota is under the surveillance of the normal mucosal immune system. Inflammation, which is caused by abnormal immune responses,influences the balance of the gut microbiome, resulting in intestinal diseases. In this review, we briefly outlined the interaction between the gut microbiota and the immune system and provided a reference for future studies.Na Shi Na Li Xinwang Duan Haitao Niu 2017Military Medical Research2017,4,3:65
22018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents显示文摘Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up.Cheng Wang Yaqi Li Ying Liao Hong Tian Min Huang Xiangyu Dong Lin Shi Jinghui Sun Hongfang Jin Junbao Du Jindou An Jie Chen Mingwu Chen Qi Chen Sun Chen Yonghong Chen Zhi Chen Adolphus Kai-tung Chau Junbao Du Zhongdong Du Junkai Duan Hongyu Duan Xiangyu Dong Lin Feng Lijun Fu Fangqi Gong Yonghao Gui Ling Han Zhenhui Han Bing He Zhixu He Xiufen Hu Yimin Hua Guoying Huang Min Huang Ping Huang Yujuan Huang Hongfang Jin Mei Jin Bo Li Fen Li Tao Li Xiaohui Li Xiaoyan Liu Yan Li Haitao Lv Tiewei Lv Zipu Li Luyi Ma Silin Pan Yusheng Pang Hua Peng Yuming Qin Jie Shen Lin Shi Kun Sun Jinghui Sun Hong Tian Jie Tian Cheng Wang Hong Wang Lei Wang Jinju Wang Wendi Wang Yuli Wang Rongzhou Wu Tianhe Xia Yanyan Xiao Chunhong Xie Yanlin Xing Zhenyu Xiong Baoyuan Xu Yi Xu Hui Yan Shiwei Yang Qijian Yi Xia Yu Xianyi Yu Yue Yuan Hongyan Zhang Huili Zhang Li Zhang Qingyou Zhang Xi Zhang Yanmin Zhang Zhiwei Zhang Cuifen Zhao Bin Zhou Hua Zhu 2018Science Bulletin2018,63,23:54
3Development of SSR markers from ESTs of gramineous species and their chromosome location on wheat显示文摘407,663 的一个总数表示了小麦,大麦,玉米,米饭,和蜀黍的顺序标签(EST ) ,从 GenBank/dbEST 获得了,被用来寻找简单顺序重复(SSR ) 。10,253 EST-SSRs 的一个总数,说明了 2.52% 所有 EST,被识别。用教材首相 5.0, 1367 EST-SSR 教材对被设计,哪个 715 与高质量被综合。 715 教材对在五庄稼在一样的 PCR 条件,和有效教材对下面在小麦,米饭,玉米,棉花,和大豆上被测试是 500 (69.93%), 383 (53.57%), 452 (63.22%), 357 (49.93%),并且 388 (56.27%)分别地。这显示了在扩及远距离的种类之间的 EST-SSR 标记的高可转移性。另外,有 240 loci 的 139 EST-SSR 教材对在由使用小麦的中国春天 nulli-tetrasomic 线的所有 21 个小麦染色体上是局部性的。Linzhi Li Junjun Wang Ying Guo Fangshan Jiang Yunfeng Xu Yingying Wang Haitao Pan Guanzhu Han Ruijun Li Sishen Li 2008Progress in Natural Science:Materials International2008,18,12:25
4Barometric altimetry system as virtual constellation applied in CAPS显示文摘This work describes the barometric altimetry as virtual constellation applied to the Chinese Area Positioning System (CAPS), which uses the transponders of communication satellites to transfer navigation messages to users. Barometric altimetry depends on the relationship of air pressure varying with altitude in the Earth’s atmosphere. Once the air pressure at a location is measured the site altitude can be found. This method is able to enhance and improve the availability of three-dimensional positioning. The difficulty is that the relation between barometric pressure and altitude is variable in different areas and under various weather conditions. Hence, in order to obtain higher accuracy, we need to acquire the real-time air pressure corresponding to an altimetric region’s reference height. On the other hand, the altimetry method will be applied to satellite navigation system, but the greatest difficulty lies in how to get the real-time air pressure value at the reference height in the broad areas overlaid by satellite navigation. We propose an innovational method to solve this problem. It is to collect the real-time air pressures and temperatures of the 1860 known-altitude weather observatories over China and around via satellite communication and to carry out time extrapolation forecast uniformly. To reduce data quantity, we first partition the data and encode them and then broadcast these information via navigation message to CAPS users’ receivers. Upon the interpolations being done in receivers, the reference air pressure and temperature at the receiver’s nearby place is derived. Lastly, combing with the receiver-observed real air pressure and temperature, the site’s altitude can be determined. The work is presented in the following aspects: the calculation principle, formulae, data collection, encoding, prediction, interpolation method, navigation message transmission together with errors causes and analyses. The advantages and shortcomings of the technique are discussed at the end.AI GuoXiang SHENG PeiXuan DU JinLin ZHENG YongGuang CAI XianDe WU HaiTao HU YongHui HUA Yu LI XiaoHui 2009Science China(Physics,Mechanics & Astronomy)2009,52,3:22
5The principle of the positioning system based on communication satellites显示文摘It is a long dream to realize the communication and navigation functionality in a satellite system in the world. This paper introduces how to establish the system, a positioning system based on communication satellites called Chinese Area Positioning System (CAPS). Instead of the typical navigation satellites, the communication satellites are configured firstly to transfer navigation signals from ground stations, and can be used to obtain service of the positioning, velocity and time, and to achieve the function of navigation and positioning. Some key technique issues should be first solved; they include the accuracy position determination and orbit prediction of the communication satellites, the measur- ing and calculation of transfer time of the signals, the carrier frequency drift in communication satellite signal transfer, how to improve the geometrical configuration of the constellation in the system, and the integration of navigation & communication. Several innovative methods are developed to make the new system have full functions of navigation and communication. Based on the development of crucial techniques and methods, the CAPS demonstration system has been designed and developed. Four communication satellites in the geosynchronous orbit (GEO) located at 87.5°E, 110.5°E, 134°E, 142°E and barometric altimetry are used in the CAPS system. The GEO satellites located at 134°E and 142°E are decommissioned GEO (DGEO) satellites. C-band is used as the navigation band. Dual frequency at C1=4143.15 MHz and C2=3826.02 MHz as well as dual codes with standard code (CA code and precision code (P code)) are adopted. The ground segment consists of five ground stations; the master station is in Lintong, Xi’an. The ground stations take a lot of responsibilities, including monitor and management of the operation of all system components, determination of the satellite position and prediction of the satellite orbit, accomplishment of the virtual atomic clock measurement, transmission and receiving navigation signals to and from each satellite. In the north, the south, the east, the west and the center of Chinese main land, the function of CAPS demonstration system is checked and measured. In cars and on board the system is also checked and measured. The results are as follow: CA-code, horizontal positioning accuracy, 15-25 m (1σ), vertical, 1-3 m; P-code, horizontal positioning accuracy, 8-10 m (1σ), vertical, 1-3 m; velocity accuracy, CA-code, 0.13-0.30 m/s, P-code, 0.15-0.17 m/s; time accuracy, CA-code, 160 ns, P-code, 13 ns; determination accuracy of orbit ≤2 m. About 20 million US $ and two years are spent for the development of demonstration. A complete CAPS system is now being established.AI GuoXiang SHI HuLi WU HaiTao LI ZhiGang GUO Ji 2009Science China(Physics,Mechanics & Astronomy)2009,52,3:21
6Characterization of drug responses of mini patient-derived xenografts in mice for predicting cancer patient clinical therapeutic response显示文摘Background:Patient-derived organoids and xenografts(PDXs)have emerged as powerful models in functional diag-nostics with high predictive power for anticancer drug response.However,limitations such as engraftment failure and time-consuming for establishing and expanding PDX models followed by testing drug efficacy,and inability to subject to systemic drug administration for ex vivo organoid culture hinder realistic and fast decision-making in selecting the right therapeutics in the clinic.The present study aimed to develop an advanced PDX model,namely MiniPDX,for rapidly testing drug efficacy to strengthen its value in personalized cancer treatment.Methods:We developed a rapid in vivo drug sensitivity assay,OncoVee®MiniPDX,for screening clinically relevant regimens for cancer.In this model,patient-derived tumor cells were arrayed within hollow fiber capsules,implanted subcutaneously into mice and cultured for 7 days.The cellular activity morphology and pharmacokinetics were systematically evaluated.MiniPDX performance(sensitivity,specificity,positive and negative predictive values)was examined using PDX as the reference.Drug responses were examined by tumor cell growth inhibition rate and tumor growth inhibition rate in PDX models and MiniPDX assays respectively.The results from MiniPDX were also used to evaluate its predictive power for clinical outcomes.Results:Morphological and histopathological features of tumor cells within the MiniPDX capsules matched those both in PDX models and in original tumors.Drug responses in the PDX tumor graft assays correlated well with those in the corresponding MiniPDX assays using 26 PDX models generated from patients,including 14 gastric cancer,10 lung cancer and 2 pancreatic cancer.The positive predictive value of MiniPDX was 92%,and the negative predictive value was 81%with a sensitivity of 80%and a specificity of 93%.Through expanding to clinical tumor samples,Min-iPDX assay showed potential of wide clinical application.Conclusions:Fast in vivo MiniPDX assay based on capsule implantation was developed-to assess drug responses of both PDX tumor grafts and clinical cancer specimens.The high correlation between drug responses of paired MiniPDX and PDX tumor graft assay,as well as translational data suggest that MiniPDX assay is an advanced tool for personalized cancer treatment.Feifei Zhang Wenjie Wang Yuan Long Hui Liu Jijun Cheng Lin Guo Rongyu Li Chao Meng Shan Yu Qingchuan Zhao Shun Lu Lili Wang Haitao Wang Danyi Wen 2018Cancer Communications2018,38,1:20
7Real-world fuel efficiency and exhaust emissions of light-duty diesel vehicles and their correlation with road conditions显示文摘The real-world fuel efficiency and exhaust emission profiles of CO, HC and NOx for light-duty diesel vehicles were investigated. Using a portable emissions measurement system, 16 diesel taxies were tested on different roads in Macao and the data were normalized with the vehicle specific power bin method. The 11 Toyota Corolla diesel taxies have very good fuel economy of (5.9 ± 0.6) L/100 km, while other five diesel taxies showed relatively high values at (8.5 ± 1.7) L/100 km due to the variation in transmission systems and emission control strategies. Compared to similar Corolla gasoline models, the diesel cars confirmed an advantage of ca. 20% higher fuel efficiency. HC and CO emissions of all the 16 taxies are quite low, with the average at (0.05 ± 0.02) g/km and (0.38 ± 0.15) g/km, respectively. The average NOx emission factor of the 11 Corolla taxies is (0.56 ± 0.17) g/km, about three times higher than their gasoline counterparts. Two of the three Hyundai Sonata taxies, configured with exhaust gas recirculation (EGR) + diesel oxidation catalyst (DOC) emission control strategies, indicated significantly higher NO2 emissions and NO2/NOx ratios than other diesel taxies and consequently trigger a concern of possibly adverse impacts on ozone pollution in urban areas with this technology combination. A clear and similar pattern for fuel consumption and for each of the three gaseous pollutant emissions with various road conditions was identified. To save energy and mitigate CO2 emissions as well as other gaseous pollutant emissions in urban area, traffic planning also needs improvement.Jingnan Hu Ye Wu Zhishi Wang Zhenhua Li Yu Zhou Haitao Wang Xiaofeng Bao Jiming Hao 2012Journal of Environmental Sciences2012,24,5:14
8The Qitai radio telescope显示文摘This study presents a general outline of the Qitai radio telescope(QTT)project.Qitai,the site of the telescope,is a county of Xinjiang Uygur Autonomous Region of China,located in the east Tianshan Mountains at an elevation of about 1800 m.The QTT is a fully steerable,Gregorian-type telescope with a standard parabolic main reflector of 110 m diameter.The QTT has adopted an umbrella support,homology-symmetric lightweight design.The main reflector is active so that the deformation caused by gravity can be corrected.The structural design aims to ultimately allow high-sensitivity observations from 150 MHz up to115 GHz.To satisfy the requirements for early scientific goals,the QTTwill be equipped with ultra-wideband receivers and large field-of-view multi-beam receivers.A multi-function signal-processing system based on RFSo C and GPU processor chips will be developed.These will enable the QTT to operate in pulsar,spectral line,continuum and Very Long Baseline Interferometer(VLBI)observing modes.Electromagnetic compatibility(EMC)and radio frequency interference(RFI)control techniques are adopted throughout the system design.The QTT will form a world-class observational platform for the detection of lowfrequency(nano Hertz)gravitational waves through pulsar timing array(PTA)techniques,pulsar surveys,the discovery of binary black-hole systems,and exploring dark matter and the origin of life in the universe.The QTT will also play an important role in improving the Chinese and international VLBI networks,allowing high-sensitivity and high-resolution observations of the nuclei of distant galaxies and gravitational lensing systems.Deep astrometric observations will also contribute to improving the accuracy of the celestial reference frame.Potentially,the QTT will be able to support future space activities such as planetary exploration in the solar system and to contribute to the search for extraterrestrial intelligence.Na Wang Qian Xu Jun Ma Zhiyong Liu Qi Liu Hailong Zhang Xin Pei Maozheng Chen Richard N.Manchester Kejia Lee Xingwu Zheng Hans J.Kärcher Wulin Zhao Hongwei Li Dongwei Li Martin Süss Matthias Reichert Zhongyi Zhu Congsi Wang Mingshuai Li Rui Li Ning Li Guljaina Kazezkhan Wenming Yan Gang Wu Lang Cui Ming Zhang Haitao Li 2023Science China(Physics,Mechanics & Astronomy)2023,66,8:14
9Estimation of ammonia nitrogen load from nonpoint sources in the Xitiao River catchment, China显示文摘Ammonia nitrogen (NH4+-N) is one of the three main forms of total nitrogen (TN). Most studies have estimated the load of TN from nonpoint sources instead of one specific form. The relationship between land use and concentrations of NH4+-N in runoff was analyzed using the hydraulic analysis functions of a Geographic Information Systems (GIS), and the annual loads of NH4+-N in the Xitiao River catchment were estimated according to model results. The results suggested that the calculated annual loads of NH4+-N agreed well with the observed ones, which was a good example demonstrating that it was possible to estimate the pollutant loads from nonpoint sources without enough monitoring data. Results also showed that the concentrations of NH4+-N in river waters of forest and arable land in the study area were 0.16 and 0.39 mg/L, respectively. The total nonpoint source load of NH4+-N from 1995 to 2001 (except 1998 and 2000) varied between 2,098 and 7,992 tons/year in the Xitiao River catchment.Tao LIANG Zhongyi CHONG 2008Journal of Environmental Sciences2008,20,10:13
10Prediction of pathological nodal stage of locally advanced rectal cancer by collective features of multiple lymph nodes in magnetic resonance images before and after neoadjuvant chemoradiotherapy显示文摘Objective:To predict pathological nodal stage of locally advanced rectal cancer by a radiomic method that uses collective features of multiple lymph nodes(LNs)in magnetic resonance images before and after neoadjuvant chemoradiotherapy(NCRT).Methods:A total of 215 patients were included in this study and chronologically divided into the discovery cohort(n=143)and validation cohort(n=72).In total,2,931 pre-NCRT LNs and 1,520 post-NCRT LNs were delineated from all visible rectal LNs in magnetic resonance images.Geometric,first-order and texture features were extracted from each LN before and after NCRT.Collective features are defined as the maximum,minimum,mean,median value and standard deviation of each feature from all delineated LNs of each participant.LN-model is constructed from collective LN features by logistic regression model with L1 regularization to predict pathological nodal stage(ypN0 or ypN+).Tumor-model is constructed from tumor features for comparison by using DeLong test.Results:The LN-model selects 7 features from 412 LN features,and the tumor-model selects 7 features from 82 tumor features.The area under the receiver operating characteristic curve(AUC)of LN-model in the discovery cohort is 0.818[95%confidence interval(95%CI):0.745-0.878],significantly(Z=2.09,P=0.037)larger than 0.685(95%CI:0.602-0.760)of the tumor-model.The AUC of LN-model in validation cohort is 0.812(95%CI:0.703-0.895),significantly(Z=3.106,P=0.002)larger than 0.517(95%CI:0.396-0.636)of the tumor-model.Conclusions:The usage of collective features from all visible rectal LNs performs better than the usage of tumor features for the prediction of pathological nodal stage of locally advanced rectal cancer.Haitao Zhu Xiaoyan Zhang Xiaoting Li Yanjie Shi Huici Zhu Yingshi Sun 2019Chinese Journal of Cancer Research2019,31,6:13
11Species-dependent neuropathology in transgenic SOD' aigs显示文摘Huaqiang Yang Guohao Wang Haitao Sun Runzhe Shu Tao Liu Chuan-En Wang Zhaoming Liu Yu Zhao Bentian Zhao Zhen Ouyang Dongshan Yang Jiao Huang Yueling Zhou Shihua Li Xiaodan Jiang Zhicheng Xiao Xiao-Jiang Li Liangxue Lai 2014Cell Research2014,24,4:13
12A survey on applications of semi-tensor product method in engineering显示文摘Semi-tensor product(STP) of matrices has attracted more and more attention from both control theory and engineering in the last two decades. This paper presents a comprehensive survey on the applications of STP method in engineering. Firstly, some preliminary results on STP method are recalled.Secondly, some applications of STP method in engineering, including gene regulation, power system, wireless communication, smart grid, information security, combustion engine and vehicle control, are reviewed.Finally, some potential applications of STP method are predicted.Haitao LI Guodong ZHAO Min MENG June FENG 2018Science China(Information Sciences)2018,61,1:12
13Satellite virtual atomic clock with pseudorange difference function显示文摘Satellite atomic clocks are the basis of GPS for the control of time and frequency of navigation signals. In the Chinese Area Positioning System (CAPS), a satellite navigation system without the satellite atomic clocks onboard is successfully developed. Thus, the method of time synchronization based on satellite atomic clocks in GPS is not suitable. Satellite virtual atomic clocks are used to implement satellite navigation. With the satellite virtual atomic clocks, the time at which the signals are transmitted from the ground can be delayed into the time that the signals are transmitted from the satellites and the pseudorange measuring can be fulfilled as in GPS. Satellite virtual atomic clocks can implement the navigation, make a pseudorange difference, remove the ephemeris error, and improve the accuracy of navigation positioning. They not only provide a navigation system without satellite clocks, but also a navigation system with pseudorange difference.LI XiaoHui WU HaiTao BIAN YuJing WANG DanNi 2009Science China(Physics,Mechanics & Astronomy)2009,52,3:11
14Hybrid hierarchy storage system in MilkyWay-2 supercomputer显示文摘Weixia XU Yutong LU Qiong LI Enqiang ZHOU Zhenlong SONG Yong DONG Wei ZHANG Dengping WEI Xiaoming ZHANG Haitao CHEN Jianying XING Yuan YUAN 2014Frontiers of Computer Science2014,8,3:11
15Carbon-nitrogen/graphene composite as metal-free electrocatalyst for the oxygen reduction reaction显示文摘Sheet-like carbon-nitrogen (CNx)/graphene composites with a high content of nitrogen (x≤0.15) was prepared by the carbonization of polypyrrole (PPy)/reduced-graphene-oxide (rGO) composite at 600-800°C. We used rGO instead of graphene oxide (GO) sheets as a template and a substrate to immobilize PPy since the PPy/GO composite agglomerates easily because of the dehydration of excess oxygen-containing groups on the GO sheets during the drying process. The dried PPy/rGO intermediate and its derived CNx/graphene products retain their high dispersion and loose-powder features. The as-prepared CNx/graphene composites have a total nitrogen content of about 10 at% and their nitrogen state is mainly of pyridinic and graphitic type. CNx/graphene composites exhibit excellent performance for the oxygen reduction reaction (ORR) in terms of electrocatalytic activity, stability and immunity towards methanol crossover and CO poisoning, suggesting their potential as metal-free electrocatalysts for the ORR.MA YanWen ZHANG LingRong LIJuanJuan NI HaiTao LI Meng ZHANG JinLei FENG XiaoMiao FAN QuLi HU Zheng HUANG Wei 2011Chinese Science Bulletin2011,56,33:11
16Ultrafast fiber lasers mode-locked by two-dimensional materials:review and prospect显示文摘The year 2019 marks the 10th anniversary of the first report of ultrafast fiber laser mode-locked by graphene.This result has had an important impact on ultrafast laser optics and continues to offer new horizons.Herein,we mainly review the linear and nonlinear photonic properties of two-dimensional(2D)materials,as well as their nonlinear applications in efficient passive mode-locking devices and ultrafast fiber lasers.Initial works and significant progress in this field,as well as new insights and challenges of 2D materials for ultrafast fiber lasers,are reviewed and analyzed.TIAN JIANG KE YIN CONG WANG JIE YOU HAO OUYANG RUNLIN MIAO CHENXI ZHANG KE WEI HAN LI HAITAO CHEN RENYAN ZHANG XIN ZHENG ZHONGJIE XU XIANGAI CHENG HAN ZHANG 2020Photonics Research2020,8,1:11
17Two kinds of optimal controls for probabilistic mix-valued logical dynamic networks显示文摘This paper addresses two kinds of optimal control problems of probabilistic mix-valued logical control networks by using the semi-tensor product of matrices,and presents a number of new results on the optimal finite-horizon control and the first-passage model based control problems,respectively.Firstly,the probabilistic mix-valued logical control network is expressed in an algebraic form by the semi-tensor product method,based on which the optimal finite-horizon control problem is studied and a new algorithm for choosing a sequence of control actions is established to minimize a given cost functional over finite steps.Secondly,the first-passage model of probabilistic mix-valued logical networks is given and a new algorithm for designing the optimal control scheme is proposed to maximize the corresponding probability criterion.Finally,an illustrative example is studied to support our new results/algorithms.LIU ZhenBin WANG YuZhen LI HaiTao 2014Science China(Information Sciences)2014,57,5:11
18Near-field surface movement during the Wenchuan M_s8.0 earthquake measured by high-rate GPS显示文摘Based on high-rate (1 Hz) GPS data from the Sichuan GPS Continuous Observation Network on the footwall of the Longmenshan Fault, we have characterized the near-field surface movement process during the 5.12 Wenchuan Earthquake. Results show that the maximum deformation near the fault is larger than the deformation set. Stations on the northern segment of the fault moved towards the epicenter first, and then turned toward the vertical orientation of the fault. Deformation of stations on the southern segment is smaller and recovered. The initial motion at all of the stations was downward followed by periodic up and down movements. Comparing the displacement from high-rate GPS and accelerograph data, we can see that they are consistent prior to the arrival of the principal shock, but afterwards a 10 cm difference is found, even though they are synchronized and in phase. More work is yet to be done to explain this. This is the first time that actual the real near-field surface movements of an earth- quake of M >7.0 have been determined in china. These measurements are therefore of high value for studies of surface rupture processes and the analysis of seismic wave travels paths in this region.YIN HaiTao ZHANG PeiZhen GAN WeiJun WANG Min LIAO Hua LI XiaoJun LI Jie XIAO GenRu 2010Chinese Science Bulletin2010,55,23:11
19Plant HP1 protein ADCP1 links multivalent H3K9 methylation readout to heterochromatin formation显示文摘Heterochromatin Protein 1 (HP1) recognizes histone H3 lysine 9 methylation (H3K9me) through its conserved chromodomain and maintains heterochromatin from fission yeast to mammals. However, in Arabidopsis, Like Heterochromatin Protein 1 (LHP1) recognizes and colocalizes genome-wide with H3K27me3, and is the functional homolog of Polycomb protein. This raises the question whether genuine HP1 homologs exist in plants. Here, we report on the discovery of ADCP1, a plant-specific triple tandem Agenet protein, as a multivalent H3K9me reader in Arabidopsis, and establish that ADCP1 is essential for heterochromatin formation and transposon silencing through modulating H3K9 and DNA methylation levels. Structural studies revealed the molecular basis underlying H3K9me-specific recognition by tandem Agenet of ADCP1. Similar to human HP1α and fly HP1a, ADCP1 mediates heterochromatin phase separation. Our results demonstrate that despite its distinct domain compositions, ADCP1 convergently evolves as an HP1-equivalent protein in plants to regulate heterochromatin formation.Shuai Zhao Lingling Cheng Yifei Gao Baichao Zhang Xiangdong Zheng Liang Wang Pilong Li Qianwen Sun Haitao Li 2019Cell Research2019,29,1:10
20Distribution, geochemistry and age of the Millennium eruptives of Changbaishan volcano, Northeast China - A review显示文摘大爆炸暴烈的爆发产生为识别火山的来源提供有利条件的广泛的地区性的 tephra 存款,比较一个区域的沉积阶层并且决定他们的年龄。tephra 层,叫作 B-Tm,由 Changbaishan 火山的千年爆发产生了,广泛地在东北中国,日本, D.P.R 朝鲜,和俄国的附近沿海的区域被散布。它形成普遍东北亚洲人阶层的部分并且为建立一个等时的 stratigraphic 框架是重要的。然而,用这 tephra 层在时间的描述和联系阶层的 stratigraphic 关联上研究主要被集中在并且在日本附近。在东北中国,这 tephra 层很少被看见,它在 stratigraphic 关联的申请甚至更稀罕。更重要地,为远侧、近似的 tephras 的精确年龄的决心被辩论了,导致在它的环境影响的讨论的争吵。从这爆发通常发生在 1,012 和 1,004 cal 年 BP 之间的远侧、近似的 Changbaishan 灰表演的 Stratigraphic 记录。在在日本附近的 Changbaishan 灰和第四级的普遍的灰之间的 Geochemical 比较说明 Changbaishan 灰是从 rhyolitic 的一篇连续作文到 trachytic 和它到 CaO 的 FeO ^潜水艇 T ^的比率,这通常比 4 大,它能在全球当代的爆发之中被用作一个区分的标识符[出版摘要]Chunqing SUN Haitao YOU Jiaqi LIU Xin LI Jinliang GAO Shuangshuang CHEN 2014Frontiers of Earth Science2014,8,2:10
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