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| 1 | Tuning oxygen vacancies in two-dimensional iron-cobalt oxide nanosheets through hydrogenation for enhanced oxygen evolution activity显示文摘 | Linzhou Zhuang Yi Jia Tianwei He Aijun Du Xuecheng Yan Lei Ge Zhonghua Zhu Xiangdong Yao | 2018 | Nano Research2018，11，6： | 10 |
| 2 | Comparative Genome Analysis of Scutellaria baicalensis and Scutellaria barbata Reveals the Evolution of Active Flavonoid Biosynthesis显示文摘Scutellaria baicalensis(S.baicalensis)and Scutellaria barbata(S.barbata)are common medicinal plants of the Lamiaceae family.Both produce specific flavonoid compounds,including baicalein,scutellarein,norwogonin,and wogonin,as well as their glycosides,which exhibit antioxidant and antitumor activities.Here,we report chromosome-level genome assemblies of S.baicalensis and S.barbata with quantitative chromosomal variation(2 n=18 and 2 n=26,respectively).The divergence of S.baicalensis and S.barbata occurred far earlier than previously reported,and a whole-genome duplication(WGD)event was identified.The insertion of long terminal repeat elements after speciation might be responsible for the observed chromosomal expansion and rearrangement.Comparative genome analysis of the congeneric species revealed the species-specific evolution of chrysin and apigenin biosynthetic genes,such as the S.baicalensis-specific tandem duplication of genes encoding phenylalanine ammonia lyase and chalcone synthase,and the S.barbata-specific duplication of genes encoding 4-Co A ligase.In addition,the paralogous duplication,colinearity,and expression diversity of CYP82 D subfamily members revealed the functional divergence of genes encoding flavone hydroxylase between S.baicalensis and S.barbata.Analyzing these Scutellaria genomes reveals the common and species-specific evolution of flavone biosynthetic genes.Thus,these findings would facilitate the development of molecular breeding and studies of biosynthesis and regulation of bioactive compounds. | Zhichao Xu Ranran Gao Xiangdong Pu Rong Xu Jiyong Wang Sihao Zheng Yan Zeng Jun Chen Chunnian He Jingyuan Song | 2020 | Genomics, Proteomics & Bioinformatics2020，18，3： | 10 |
| 3 | PandaX: a liquid xenon dark matter experiment at CJPL显示文摘PandaX is a large liquid-xenon detector experiment usable for direct dark-matter detection and 136Xe double-beta decay search.The central vessel was designed to accommodate a staged target volume increase from initially 120 kg(stage I)to 0.5 t(stage II)and eventually to a multi-ton scale.The experiment is located in the Jinping Deep-Underground Laboratory in Sichuan,China.The detector operates in dual-phase mode,allowing detection of both prompt scintillation,and ionization charge through proportional scintillation.In this paper a detailed description of the stage I detector design and performance as well as results established during the commissioning phase are presented. | CAO XiGuang CHEN Xun CHEN YunHua CUI XiangYi FANG DeQing FU ChangBo GIBONI Karl L. GONG HaoWei GUO GuoDong HE Ming HU Jie HUANG XingTao JI XiangDong JU YongLin LI ShaoLi LIN Qing LIU HuaXuan LIU JiangLai LIU Xiang LORENZON Wolfgang MA YuGang MAO YaJun NI KaiXuan PUSHKIN Kirill REN XiangXiang SCHUBNELL Michael SHEN ManBing SHI YuJie STEPHENSON Scott TAN AnDi TARLé Greg WANG HongWei WANG JiMing WANG Meng WANG XuMing WANG Zhou WEI YueHuan WU ShiYong XIAO MengJiao XIAO Xiang XIE PengWei YE Tao YOU YingHui ZEN XiongHui ZHANG Hua ZHANG Tao ZHAO HaiYing ZHAO Li ZHOU XiaoPeng ZHU ZhongHua | 2014 | Science China(Physics,Mechanics & Astronomy)2014，57，8： | 9 |
| 4 | Wheat genomic study for genetic improvement of traits in China显示文摘Bread wheat(Triticum aestivum L.)is a major crop that feeds 40%of the world’s population.Over the past several decades,advances in genomics have led to tremendous achievements in understanding the origin and domestication of wheat,and the genetic basis of agronomically important traits,which promote the breeding of elite varieties.In this review,we focus on progress that has been made in genomic research and genetic improvement of traits such as grain yield,end-use traits,flowering regulation,nutrient use efficiency,and biotic and abiotic stress responses,and various breeding strategies that contributed mainly by Chinese scientists.Functional genomic research in wheat is entering a new era with the availability of multiple reference wheat genome assemblies and the development of cutting-edge technologies such as precise genome editing tools,highthroughput phenotyping platforms,sequencing-based cloning strategies,high-efficiency genetic transformation systems,and speed-breeding facilities.These insights will further extend our understanding of the molecular mechanisms and regulatory networks underlying agronomic traits and facilitate the breeding process,ultimately contributing to more sustainable agriculture in China and throughout the world. | Jun Xiao Bao Liu Yingyin Yao Zifeng Guo Haiyan Jia Lingrang Kong Aimin Zhang Wujun Ma Zhongfu Ni Shengbao Xu Fei Lu Yuannian Jiao Wuyun Yang Xuelei Lin Silong Sun Zefu Lu Lifeng Gao Guangyao Zhao Shuanghe Cao Qian Chen Kunpu Zhang Mengcheng Wang Meng Wang Zhaorong Hu Weilong Guo Guoqiang Li Xin Ma Junming Li Fangpu Han Xiangdong Fu Zhengqiang Ma Daowen Wang Xueyong Zhang Hong-Qing Ling Guangmin Xia Yiping Tong Zhiyong Liu Zhonghu He Jizeng Jia Kang Chong | 2022 | Science China(Life Sciences)2022，65，9： | 9 |
| 5 | Permian integrative stratigraphy and timescale of China显示文摘A series of global major geological and biological events occurred during the Permian Period. Establishing a highresolution stratigraphic and temporal framework is essential to understand their cause-effect relationship. The official International timescale of the Permian System consists of three series(i.e., Cisuralian, Guadalupian and Lopingian in ascending order) and nine stages. In China, the Permian System is composed of three series(Chuanshanian, Yansingian and Lopingian) and eight stages, of which the subdivisions and definitions of the Chuanshanian and Yangsingian series are very different from the Cisuralian and Guadalupian series. The Permian Period spanned ~47 Myr. Its base is defined by the First Appearance Datum(FAD) of the conodont Streptognathodus isolatus at Aidaralash, Kazakhstan with an interpolated absolute age 298.9±0.15 Ma at Usolka, southern Urals, Russia. Its top equals the base of the Triassic System and is defined by the FAD of the conodont Hindeodus parvus at Meishan D section, southeast China with an interpolated absolute age 251.902±0.024 Ma. Thirty-five conodont, 23 fusulinid, 17 radiolarian and 20 ammonoid zones are established for the Permian in China, of which the Guadalupian and Lopingian conodont zones have been served as the standard for international correlation. The Permian δ13 Ccarbtrend indicates that it is characterized by a rapid negative shift of 3–5‰ at the end of the Changhsingian, which can be used for global correlation of the end-Permian mass extinction interval, but δ13 Ccarbrecords from all other intervals may have more or less suffered subsequent diagenetic alteration or represented regional or local signatures only. Permian δ18 Oapatitestudies suggest that an icehouse stage dominated the time interval from the late Carboniferous to Kungurian(late Cisuralian). However, paleoclimate began to ameriolate during the late Kungurian and gradually shifted into a greenhouse-dominated stage during the Guadalupian.The Changhsingian was a relatively cool stage, followed by a globally-recognizable rapid temperature rise of 8–10°C at the very end of the Changhsingian. The87 Sr/86 Sr ratio trend shows that their values at the beginning of the Permian were between 0.70800,then gradually decreased to the late Capitanian minimum 0.70680–0.70690, followed by a persistent increase until the end of the Permian with the value 0.70708. Magenetostratigraphy suggests two distinct stages separated by the Illawarra Reversal in the middle Wordian, of which the lower is the reverse polarity Kiaman Superchron and the upper is the mixed-polarity Illawarra Superchron. The end-Guadalupian(or pre-Lopingian) biological crisis occurred during the late Capitanian, when faunal changeovers of different fossil groups had different paces, but generally experienced a relatively long time from the Jinogondolella altudensis Zone until the earliest Wuchiapingian. The end-Permian mass extinction was a catastrophic event that is best constrained at the Meishan section, which occurred at 251.941±0.037 Ma and persisted no more than 61±48 kyr. After the major pulse at Bed 25, the extinction patterns are displayed differently in different sections. The global end-Guadalupian regression is manifested between the conodont Jinogondolella xuanhanensis and Clarkina dukouensis zones and the endChanghsingian transgression began in the Hindeodus changxingensis-Clarkina zhejiangensis Zone. The Permian Period is also characterized by strong faunal provincialism in general, which resulted in difficulties in inter-continental and inter-regional correlation of both marine and terrestrial systems. | Shuzhong SHEN Hua ZHANG Yichun ZHANG Dongxun YUAN Bo CHEN Weihong HE Lin MU Wei LIN Wenqian WANG Jun CHEN Qiong WU Changqun CAO Yue WANG Xiangdong WANG | 2019 | Science China Earth Sciences2019，62，1： | 9 |
| 6 | Review of research in internal-wave and internal-tide deposits of China显示文摘Study of internal-wave and internal-tide deposits is a very young research field in deep-water sedimentology. It has been just twenty years since the first example of internal-wave and internal-tide deposits was identified in the stratigraphic record. Since that time, Chinese scholars have made unremitting efforts and gained some significant research achievements in this field. This paper briefly outlines the history and main achievements of research of internal-wave and internal-tide deposits in China, describes depositional charac-teristics, sedimentary successions, types of lithofacies, and depositional models of internal-wave and internal-tide deposits identified mainly from ancient strata, and summarizes the existing problems in this research field. New advances in marine physics should be applied to research of the subject of internal-wave and internal-tide deposition, whereas the sedimentary characteristics of internal-wave and internal-tide deposits may be used to deduce the physical processes of their creation. Flume experiments on internal-wave and internal-tide deposition should also be put in practice as often as possible, so that the mechanisms of internal-wave and internal-tide deposition can be explored. | Gao Zhenzhong He Youbin Li Xiangdong Duan Taizhong | 2013 | Journal of Palaeogeography2013，2，1： | 9 |
| 7 | System reliability analysis for kinematic performance of planar mechanisms显示文摘Based on the reliability and mechanism kinematic accuracy theories, we propose a general methodology for system reliability analysis of kinematic performance of planar mechanisms. The loop closure equations are used to estimate the kinematic performance errors of planar mechanisms. Reliability and system reliability theories are introduced to develop the limit state functions (LSF) for failure of kinematic performance qualities. The statistical fourth moment method and the Edgeworth series technique are used on system reliability analysis for kinematic performance of planar mechanisms, which relax the restrictions of probability distribution of design variables. Finally, the practicality, efficiency and accuracy of the proposed method are demonstrated by numerical examples. | ZHANG YiMin HUANG XianZhen ZHANG XuFang HE XiangDong WEN BangChun | 2009 | Chinese Science Bulletin2009，54，14： | 9 |
| 8 | Organotin compounds in surface sediments from selected fishing ports along the Chinese coast显示文摘The concentrations and species of organotin compounds(OTCs) in 52 surface sediment samples from nine fishing ports along the Chinese coast were studied.Butyltins(BTs) and phenyltins(PhTs) were derivatized using sodium tetraethylborate(NaBEt 4) and determined by head-space solid-phase microextraction(HS-SPME) gas chromatography coupled with a flame photometric detector(GC-FPD).The concentrations of OTCs ranged from <3.6 to 194 ng(Sn) g-1 dry weight(dw) for monobutyltin(MBT),<2.3 to 41.5 ng(Sn) g-1 dw for dibutyltin(DBT),<0.7 to 86.0 ng(Sn) g-1 dw for tributyltin(TBT) and <5.1 to 66.1 ng(Sn) g-1 dw for monophenyltin(MPhT),respectively.The concentrations of diphenyltin(DPhT) and triphenyltin(TPhT) were below the limit of detection(LOD).BTs were the main species in the sediments except for the samples collected from Shazikou fishing port in Qingdao.The concentrations of MBT were higher than DBT and TBT.The concentrations of OTCs in the sediments varied widely among different sampling locations.The concentrations of BTs were much higher in the samples collected from fishing ports close to the South China Sea than those in coast of the East China Sea and the Yellow Sea.MPhT was prevalent in most sampling stations except for those in coast of the East China Sea.The environmental and ecotoxicological risks of TBT in most sediment samples were low. | ZHANG KeGang SHI JianBo HE Bin XU WeiHai LI XiangDong JIANG GuiBin | 2013 | Chinese Science Bulletin2013，58，2： | 7 |
| 9 | The biological effect of recombinant humanized collagen on damaged skin induced by UV-photoaging:An in vivo study显示文摘The application of medical devices to repair skin damage is clinically accepted and natural polymer enjoys an important role in this field,such as collagen or hyaluronic acid,etc.However,the biosafety and efficacy of these implants are still challenged.In this study,a skin damage animal model was prepared by UV-photoaging and recombinant humanized type Ⅲ collagen(rhCol Ⅲ)was applied as a bioactive material to implant in vivo to study its biological effect,comparing with saline and uncrosslinked hyaluronic acid(HA).Animal skin conditions were non-invasively and dynamically monitored during the 8 weeks experiment.Histological observation,specific gene expression and other molecular biological methods were applied by the end of the animal experiment.The results indicated that rhCol Ⅲ could alleviate the skin photoaging caused by UV radiation,including reduce the thickening of epidermis and dermis,increase the secretion of Collagen Ⅰ(Col Ⅰ)and Collagen Ⅲ(Col Ⅲ)and remodel of extracellular matrix(ECM).Although the cell-material interaction and mechanism need more investigation,the effect of rhCol Ⅲ on damaged skin was discussed from influence on cells,reconstruction of ECM,and stimulus of small biological molecules based on current results.In conclusion,our findings provided rigorous biosafety information of rhCol Ⅲ and approved its potential in skin repair and regeneration.Although enormous efforts still need to be made to achieve successful translation from bench to clinic,the recombinant humanized collagen showed superiorities from both safety and efficacy aspects. | Jing Wang He Qiu Yang Xu Yongli Gao Peijie Tan Rui Zhao Zhanhong Liu Yajun Tang Xiangdong Zhu Chongyun Bao Hang Wang Hai Lin Xingdong Zhang | 2022 | Bioactive Materials2022，7，5： | 7 |
| 10 | Dark matter direct search sensitivity of the PandaX-4T experiment显示文摘The Panda X-4T experiment, a 4-ton scale dark matter direct detection experiment, is being planned at the China Jinping Underground Laboratory. In this paper we present a simulation study of the expected background in this experiment. In a 2.8-ton fiducial mass and the signal region between 1-10 keV electron equivalent energy, the total electron recoil background is found to be 4.9 × 10^(-5) kg^(-1) d^(-1) keV^(-1). The nuclear recoil background in the same region is 2.8 × 10^(-7) kg^(-1) d^(-1) keV^(-1). With an exposure of 5.6 ton-years, the sensitivity of Panda X-4 T could reach a minimum spin-independent dark matter-nucleon cross section of 6 × 10^(-48) cm^2 at a dark matter mass of 40 Ge V/c^2. | HongGuang Zhang Abdusalam Abdukerim Wei Chen Xun Chen YunHua Chen XiangYi Cui BinBin Dong DeQing Fang ChangBo Fu Karl Giboni Franco Giuliani LinHui Gu XuYuan Guo ZhiFan Guo Ke Han ChangDa He ShengMing He Di Huang XingTao Huang Zhou Huang Peng Ji XiangDong Ji YongLin Ju ShaoLi Li Yao Li Heng Lin HuaXuan Liu JiangLai Liu YuGang Ma YaJun Mao KaiXiang Ni JinHua Ning XiangXiang Ren Fang Shi AnDi Tan AnQing Wang Cheng Wang HongWei Wang Meng Wang QiuHong Wang SiGuang Wang XiuLi Wang XuMing Wang Zhou Wang MengMeng Wu ShiYong Wu JingKai Xia MengJiao Xiao PengWei Xie BinBin Yan JiJun Yang Yong Yang ChunXu Yu JuMin Yuan JianFeng Yue Dan Zhang Tao Zhang Li Zhao QiBin Zheng JiFang Zhou Ning Zhou XiaoPeng Zhou | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，3： | 6 |
| 11 | Human movement monitoring and behavior recognition for intelligent sports using customizable and flexible triboelectric nanogenerator显示文摘Effective collection,recognition,and analysis of sports information is the key to intelligent sports,which can help athletes to improve their skills and formulate scientific training plans and competition strategies.At present,wearable electronic devices used for movement monitoring still have some limitations,such as high cost and energy consumption,incompatibility of suitable flexibility and personalized spatial structure,dissatisfactory data analysis methods,etc.In this work,a novel three-dimensionalprinted thermoplastic polyurethane is introduced as the elastic shell and friction layer,and it endows the proposed customizable and flexible triboelectric nanogenerator(CF-TENG)with personalized spatial structure and robust correlation to external pressure.In practical application,it exhibits highly sensitive responses to the joint-bending motion of the finger,wrist,or elbow.Furthermore,a pressure-sensing insole and smart ski pole based on CF-TENG are manufactured to build a comprehensive sports monitoring system to transmit the athletes’motion information from feet and hands through the plantar pressure distribution and ski pole action.To recognize the movement status,the self-developed automatic peak recognition algorithm(P-Find)and machine learning algorithm(subspace K-Nearest Neighbors)were introduced to accurately distinguish the four typical motion behaviors and three primary sub-techniques of cross-country skiing,with accuracy rates of 98.2%and 100%.This work provides a novel strategy to promote the personalized applications of TENGs in intelligent sports. | YANG Yun HOU XiaoJuan GENG WenPing MU JiLiang ZHANG Le WANG XiangDong HE Jian XIONG Ji Jun CHOU XiuJian | 2022 | Science China(Technological Sciences)2022，65，4： | 6 |
| 12 | Host-Associated Quantitative Abundance Profiling Reveals the Microbial Load Variation of Root Microbiome显示文摘Plant-associated microbes are critical for plant growth and survival under natural environmental conditions.To date,most plant microbiome studies involving high-throughput amplicon sequencing have focused on the relative abundance of microbial taxa.However,this technique does not assess the total microbial load and the abundance of individual microbes relative to the amount of host plant tissues.Here,we report the development of a host-associated quantitative abundance profiling(HA-QAP)method that can accurately examine total microbial load and colonization of individual root microbiome members relative to host plants by the copy-number ratio of microbial marker gene to plant genome.We validate the HAQAP method using mock experiments,perturbation experiments,and metagenomic sequencing.The HA-QAP method eliminates the generation of spurious outputs in the classical method based on microbial relative abundance,and reveals the load of root microbiome to host plants.Using the HA-QAP method,we found that the copy-number ratios of microbial marker genes to plant genome range from 1.07 to 6.61 for bacterial 16S rRNA genes and from 0.40 to 2.26 for fungal internal transcribed spacers in the root microbiome samples from healthy rice and wheat.Furthermore,using HA-QAP we found that an increase in total microbial load represents a key feature of changes in root microbiome of rice plants exposed to drought stress and of wheat plants with root rot disease,which significantly influences patterns of differential taxa and species interaction networks.Given its accuracy and technical feasibility,HA-QAP would facilitate our understanding of genuine interactions between root microbiome and plants. | Xiaoxuan Guo Xiaoning Zhang Yuan Qin Yong-Xin Liu Jingying Zhang Na Zhang Kun Wu Baoyuan Qu Zishan He Xin Wang Xinjian Zhang Stephane Hacquard Xiangdong Fu Yang Bai | 2020 | Plant Communications2020，1，1： | 3 |
| 13 | Aligned fibrin/functionalized self-assembling peptide interpenetrating nanofiber hydrogel presenting multi-cues promotes peripheral nerve functional recovery显示文摘Nerve guidance conduits with hollow lumen fail to regenerate critical-sized peripheral nerve defects(15 mm in rats and 25 mm in humans),which can be improved by a beneficial intraluminal microenvironment.However,individual cues provided by intraluminal filling materials are inadequate to eliminate the functional gap between regenerated nerves and normal nerves.Herein,an aligned fibrin/functionalized self-assembling peptide(AFG/fSAP)interpenetrating nanofiber hydrogel that exerting synergistic topographical and biochemical cues for peripheral nerve regeneration is constructed via electrospinning and molecular self-assembly.The hydrogel possesses an aligned structure,high water content,appropriate mechanical properties and suitable biodegradation capabilities for nerve repair,which enhances the alignment and neurotrophin secretion of primary Schwann cells(SCs)in vitro,and successfully bridges a 15-mm sciatic nerve gap in rats in vivo.The rats transplanted with the AFG/fSAP hydrogel exhibit satisfactory morphological and functional recovery in myelinated nerve fibers and innervated muscles.The motor function recovery facilitated by the AFG/fSAP hydrogel is comparable with that of autografts.Moreover,the AFG/fSAP hydrogel upregulates the regeneration-associated gene expression and activates the PI3K/Akt and MAPK signaling pathways in the regenerated nerve.Altogether,the AFG/fSAP hydrogel represents a promising approach for peripheral nerve repair through an integration of structural guidance and biochemical stimulation. | Shuhui Yang Jinjin Zhu Changfeng Lu Yi Chai Zheng Cao Jiaju Lu Zhe Zhang He Zhao Yin-Yuan Huang Shenglian Yao Xiangdong Kong Peixun Zhang Xiumei Wang | 2022 | Bioactive Materials2022，7，2： | 3 |
| 14 | Periostin mediates epithelial-mesenchymal transition through the MAPK/ERK pathway in hepatoblastoma显示文摘Objective: The aim of the present study was to analyze the prognostic factors in patients with hepatoblastoma(HB) in our single center and to evaluate periostin(POSTN) expression in HB and its association with clinicopathological variables. In addition, the underlying mechanism of how POSTN promotes HB progression was discussed.Methods: POSTN expression was investigated in HB tumors by immunohistochemistry(IHC), immunofluorescence(IF) and Western blot(WB). The association among POSTN expression, clinicopathological features and overall survival(OS) was also evaluated. The migration and adhesion ability of HB cells were measured using chemotaxis and cell-matrix adhesion assays,respectively. Epithelial-mesenchymal transition(EMT)-associated markers and activation of the ERK pathway were detected by WB.Results: HB patients had poor prognosis which displayed lymph node metastasis, vascular invasion, POSTN and vimentin expression. POSTN expression was also associated with lymph node metastasis. Furthermore, overexpressed POSTN promoted migration and the adhesive ability of HB cells in vitro. In addition, we demonstrated that POSTN activated the MAPK/ERK pathway, upregulated the expression of Snail and decreased the expression of OVOL2. Finally, POSTN promoted the expression of EMT-associated markers.Conclusions: POSTN might modulate EMT via the ERK signaling pathway, thereby promoting cellular migration and invasion.Our study also suggests that POSTN may serve as a therapeutic biomarker in HB patients. | Lu Chen Xiangdong Tian Wenchen Gong Bo Sun Guangtao Li Dongming Liu Piao Guo Yuchao He Ziye Chen Yuren Xia Tianqiang Song Hua Guo | 2019 | Cancer Biology & Medicine2019，16，1： | 3 |
| 15 | Enhancement of strength-ductility balance of heavy Ti and Al alloyed FeCoNiCr high-entropy alloys via boron doping显示文摘As one of the most effective mechanisms,precipitation-hardening is widely used to strengthen high-entropy alloys.Yet,heavy precipitation-hardened high-entropy alloys usually exhibit serious embrittlement.How to effectively achieve ultra-high strength and maintain reliable ductility remains a challenge.Here,we report a study of doping extremely little boron to meet this target.We found that adding of 30 ppm boron into the heavy Ti and Al alloyed FCC FeCoNiCr high-entropy,(FeCoNiCr)_(88) Ti_(6) Al_(6) HEA(at.%)which is strengthened mainly by both coarse BCC-based(Ni,Co)_(2) TiAl Heusler and fine L12-type FCC-based(Ni,Co)_(3) TiAl precipitates and shows ultrahigh strength but poor ductility,could significantly change the original microstructure and consequently improve mechanical performance,owing to the well-known effect of boron on reducing the energy of grain boundaries.The boron addition can(1)eliminate microcavities formed at Heusler precipitate-matrix interfaces;(2)suppress the formation and segregation of coarse BCC Heusler precipitates;(3)promote the formation of L12 nanoparticles.This changes of microstructure substantially improve the tensile ductility more than by~86%and retain comparable or even better ultimate tensile strength.These findings may provide a simple and costless solution to produce heavy precipitation-strengthened HEAs with ultrahigh strength and prevent accidental brittleness. | Yongliang Qi Tinghui Cao Hongxiang Zong Yake Wu Lin He Xiangdong Ding Feng Jiang Shenbao Jin Gang Sha Jun Sun | 2021 | Journal of Materials Science & Technology2021，，16： | 2 |
| 16 | Microstructural evolution and hardness of as-cast Be-Al-Sc-Zr alloy processed by laser surface remelting显示文摘As-cast beryllium-aluminum(Be-Al)alloy exhibits a coarse microstructure with pore defects due to a large solidification interval,greatly limiting its mechanical properties.In this research,the relationship between laser surface remelting process and microstructure and hardness of as-cast Be-Al-Sc-Zr alloy was established.The experimental results demonstrated that a pore-free refined microstructure of remelted layer was obtained by controlling the parameter of effective laser energy input.The microstructure of as-cast Be-Al-Sc-Zr alloy consisted of equiaxed grains with Al phase forming a continuous frame wrapping Be phase,which was significantly refined in the remelted zone(from 25μm to 2μm).The Vickers hardness in the remelted zone(approximately 210 HV)was approximately 3 times that of as-cast Be-Al-Sc-Zr alloy.Analysis of the Vickers hardness and the Be phase size showed a good agreement with a Hall-Petch equation.In addition,transmission electron microscopy(TEM),auger electron spectroscopy(AES)and X-ray diffraction(XRD)analysis evidenced that Sc and Zr elements formed a single blocky phase Be13(Scx,Zr1-x),which was also greatly refined from 8μm to 1.5μm in the remelted zone.The results obtained in this study indicate that the laser surface remelting allowed refining the microstructure and further strengthening the Vickers hardness of Be-Al-Sc-Zr alloy. | Qingdong XU Yu LUO Xiangdong LIU Lei YANG Shixiong HE Xin WANG Wenyuan WANG Tao SHI Ruiwen LI Pengcheng ZHANG | 2021 | Chinese Journal of Aeronautics2021，34，8： | 2 |
| 17 | Hybrid photoanode films based on sparse ZnO rod array-TiO_2 nanoparticles in dye-sensitized solar cells显示文摘ZnO-TiO2 hybrid photoanodes were fabricated via the doctor-blade method by integrating vertically-grown sparse ZnO arrays with hydrothermal TiO2 nanoparticles. A special surface-coating technique was developed to deposit a thin TiO2 layer on the surface of ZnO rods. Microstructure, optical and photoelectrochemical performance of the hybrid photoanodes were investigated. The denser ZnO array exhibited bad filling behavior of nanoparticles in the interspace of ZnO rods, strong scattering and low conversion efficiency (0.27%). The sparser array showed a much better integrated microstructure, improved transmittance and high conversion efficiency (2.68%). The surface modification of ZnO rods by the TiO2 thin layer was found useful in improving the interfacial microstructure between the ZnO rod and the TiO2 bulk film, and the total conversion efficiency of 3.01% was achieved, higher than that of the pure TiO2 nanoparticle cell (2.93%). The increased scattering effects on the incident light, the enhanced electron transportation at TiO2/dye/electrolyte interface, and the inhabited recombination were responsible for this improvement. | WANG CaiLu GAO XiangDong LI XiaoMin JIANG ZhengWu YANG ZhengHong GU ZhengYing HE Peng | 2012 | Science China(Physics,Mechanics & Astronomy)2012，55，7： | 2 |
| 18 | Research and development of a novel subunit vaccine for the currently circulating pseudorabies virus variant in China显示文摘Pseudorabies(PR)is a devastating viral disease which leads to fatal encephalitis and respiratory disorders in pigs.Commercial gE-deleted live pseudorabies virus(PRV)vaccine has been widely used to control this disease in China.However,the new-emerging variants of PRV compromises the protection provided by current vaccines and lead to the outbreak of PR in vaccinated pig herds.Several killed and live vaccine candidates based on current PRV variants have been reported to be effective to control the disease.A subunit vaccine based on gB protein,one major PRV glycoprotein which elicits strong humoral and cellular immune responses,however,was never evaluated for protection against the current circulating PRV variants.In this study,full-length PRV gB protein was successfully expressed in baculovirus/insect cells in the soluble format and was tested on 3-week-old piglets as a subunit vaccine.Compared with unvaccinated pigs,the gB-vaccinated pigs developed specific antibody-mediated responses and were protected from the virulent PRV HN1201 challenge.All vaccinated pigs survived without showing any PRV-specific respiratory and neurological signs,but all unvaccinated pigs died within 7 days after HN1201 challenge.Hence,this novel gB-based vaccine could be applied as an effective subunit vaccine to control PRV variant in China. | Yuzhou WANG Tongyan WANG He YAN Fanli YANG Linghua GUO Qingyuan YANG Xule HU Feifei TAN Yan XIAO Xiangdong LI Kegong TIAN | 2015 | Frontiers of Agricultural Science and Engineering2015，2，3： | 2 |
| 19 | An approach of robust reliability design for mechanical components显示文摘 | Zhang Yimin He Xiangdong Liu Qiaoling | 2005 | Proceedings of the Institution of Mechanical Engineers Part E:Journal of Process Mechanical Engineering2005，219，3： | 1 |
| 20 | Robust reliability design of banjo flange with arbitrary distribution parameters显示文摘 | Zhang Yimin He Xiangdong Liu Qiaoling | 2005 | Journal of Pressure Vessel Technology Transactions of the ASME2005，127，4： | 1 |
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