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| 1 | Dental plaque-inspired versatile nanosystem for caries prevention and tooth restoration显示文摘Dental caries is one of the most prevalent human diseases resulting from tooth demineralization caused by acid production of bacteria plaque.It remains challenges for current practice to specifically identify,intervene and interrupt the development of caries while restoring defects.In this study,inspired by natural dental plaque,a stimuli-responsive multidrug delivery system(PMs@NaF-SAP)has been developed to prevent tooth decay and promote enamel restoration.Classic spherical core-shell structures of micelles dual-loaded with antibacterial and restorative agents are self-assembled into bacteria-responsive multidrug delivery system based on the pH-cleavable boronate ester bond,followed by conjugation with salivary-acquired peptide(SAP)to endow the nanoparticle with strong adhesion to tooth enamel.The constructed PMs@NaF-SAP specifically adheres to tooth,identifies cariogenic conditions and intelligently releases drugs at acidic pH,thereby providing antibacterial adhesion and cariogenic biofilm resistance,and restoring the microarchitecture and mechanical properties of demineralized teeth.Topical treatment with PMs@NaF-SAP effectively diminishes the onset and severity of caries without impacting oral microbiota diversity or surrounding mucosal tissues.These findings demonstrate this novel nanotherapy has potential as a promising biomedical application for caries prevention and tooth defect restoration while resisting biofilm-associated diseases in a controlled manner activated by pathological bacteria. | Yue Xu Yuan You Luyao Yi Xiaoyi Wu Yaning Zhao Jian Yu He Liu Ya Shen Jingmei Guo Cui Huang | 2023 | Bioactive Materials2023，，2： | 3 |
| 2 | Design of activatable red-emissive assay for cysteine detection in aqueous medium with aggregation induced emission characteristics显示文摘A novel wate r-soluble red-emissive AIE fluorescence probe for cysteine(Cys) in situ was prepared and the performance of selectivity and sensitivity has been carefully investigated in this study.The probe was established on the electrostatic interaction of sulfonate functionalized tetraphenylethene(TPE) and polycation generated by the reaction between a polymer bearing dinitrobenzenesulfonate groups and Cys.From the experimental results,it was easy to distinguish Cys from glutathione(GSH) and homocysteine(Hcy) with a detection limit of 73 nmol/L.The assay system also possessed strong antiinterference ability against multitudinous amino acids.The Stokes shift was 142 nm and the emission ranged from 550 nm to 850 nm.In addition,double responses in fluorescence and ultraviolet-visible spectra also make the red-emissive assay ideal for sensitive detection and quantification of Cys for most purposes,especially in-situ monitoring of Cys in aqueous medium. | Bing Wu Tianhao Xue Yaning He | 2021 | Chinese Chemical Letters2021，32，2： | 2 |
| 3 | Biomarkers of aging显示文摘Aging biomarkers are a combination of biological parameters to(i)assess age-related changes,(ii)track the physiological aging process,and(iii)predict the transition into a pathological status.Although a broad spectrum of aging biomarkers has been developed,their potential uses and limitations remain poorly characterized.An immediate goal of biomarkers is to help us answer the following three fundamental questions in aging research:How old are we?Why do we get old?And how can we age slower?This review aims to address this need.Here,we summarize our current knowledge of biomarkers developed for cellular,organ,and organismal levels of aging,comprising six pillars:physiological characteristics,medical imaging,histological features,cellular alterations,molecular changes,and secretory factors.To fulfill all these requisites,we propose that aging biomarkers should qualify for being specific,systemic,and clinically relevant. | Aging Biomarker Consortium Hainan Bao Jiani Cao Mengting Chen Min Chen Wei Chen Xiao Chen Yanhao Chen Yu Chen Yutian Chen Zhiyang Chen Jagadish K Chhetri Yingjie Ding Junlin Feng Jun Guo Mengmeng Guo Chuting He Yujuan Jia Haiping Jiang Ying Jing Dingfeng Li Jiaming Li Jingyi Li Qinhao Liang Rui Liang Feng Liu Xiaoqian Liu Zuojun Liu Oscar Junhong Luo Jianwei Lv Jingyi Ma Kehang Mao Jiawei Nie Xinhua Qiao Xinpei Sun Xiaoqiang Tang Jianfang Wang Qiaoran Wang Siyuan Wang Xuan Wang Yaning Wang Yuhan Wang Rimo Wu Kai Xia Fu-Hui Xiao Lingyan Xu Yingying Xu Haoteng Yan Liang Yang Ruici Yang Yuanxin Yang Yilin Ying Le Zhang Weiwei Zhang Wenwan Zhang Xing Zhang Zhuo Zhang Min Zhou Rui Zhou Qingchen Zhu Zhengmao Zhu Feng Cao Zhongwei Cao Piu Chan Chang Chen Guobing Chen Hou-Zao Chen Jun Chen Weimin Ci Bi-Sen Ding Qiurong Ding Feng Gao Jing-Dong JHan Kai Huang Zhenyu Ju Qing-Peng Kong Ji Li Jian Li Xin Li Baohua Liu Feng Liu Lin Liu Qiang Liu Qiang Liu Xingguo Liu Yong Liu Xianghang Luo Shuai Ma Xinran Ma Zhiyong Mao Jing Nie Yaojin Peng Jing Qu Jie Ren Ruibao Ren Moshi Song Zhou Songyang Yi Eve Sun Yu Sun Mei Tian Shusen Wang Si Wang Xia Wang Xiaoning Wang Yan-Jiang Wang Yunfang Wang Catherine CL Wong Andy Peng Xiang Yichuan Xiao Zhengwei Xie Daichao Xu Jing Ye Rui Yue Cuntai Zhang Hongbo Zhang Liang Zhang Weiqi Zhang Yong Zhang Yun-Wu Zhang Zhuohua Zhang Tongbiao Zhao Yuzheng Zhao Dahai Zhu Weiguo Zou Gang Pei Guang-Hui Liu | 2023 | Science China(Life Sciences)2023，66，5： | 2 |
| 4 | Synthesis, self- assembly and photoindueed surface-relief gratings of a polyaerylate-based Azo polyeleetrolyte显示文摘 | Yaning He Haopeng Wang Xinlin Luo | 2004 | Optical Materials2004，26，： | 1 |
| 5 | Synthesis,self-assembly and photoinduced surface-relief gratings of a polyacrylate-based Azo polyelectrolyte显示文摘 | HE Yaning WANG Haopeng LUO Xinlin | 2004 | Optical Materials2004，26，： | 1 |
| 6 | Synthesis and characterization of a novel processible hyperbranched azo polymer显示文摘 | YANING HE XIAOGONG WANG QIXIANG ZHOU | 2003 | Synthetic Metals2003，132，： | 1 |
| 7 | Selective catalytic reduction of NO with NH3 over iron titanate catalyst: catalytic performance and characterization 显示文摘 | Liu Fudong He Hong Zhang Changbin Feng Zhaochi Zheng Lirong Xie Yaning Hu Tiandou | 2010 | Applied CatalysisB: Environmental2010，96，34： | 1 |
| 8 | Hollow microspheres of amphiphilic azo homopolymers: Self-assembly and photo- induced deformation behavior显示文摘 | Li Nan Ye Gang He Yaning | 2011 | Chemical Communication2011，47，16： | 1 |
| 9 | Synthesis and characterization of a novel photoprocessible hyperbranched azo polymer显示文摘 | He Yaning Wang Xiaogong Zhou Qixiang | 2003 | Synthetic Metals2003，132，： | 1 |
| 10 | Fabricating super-hydrophobic lotus-leaf-like surfaces through soft-lithographic imprinting 显示文摘 | Liu Bin He Yaning Fan Yin | 2006 | Macromolecular Rapid Communication2006，27，21： | 1 |
| 11 | Synthesis and characterization of water-soluble PEGylated lignin-based polymers by macromolecular azo coupling reaction显示文摘Water-soluble PEG grafted lignin-based polymers(AL-azo-PEG) were efficiently synthesized by macromolecular azo coupling reaction between alkali lignin and PEG based macromolecular diazonium salts in alkaline water. This one-step PEGylation method showed many advantages such as high efficiency, controllable grafting radio, extremely mild conditions and without organic solvents. The prepared AL-azo-PEG polymers were well characterized by using various spectroscopic methods including UV-vis, FTIR and ~1H NMR spectra. Experimental results showed that the synthesized polymers had good solubility both in water over a wide pH range(pH 2-12) and in the majority of organic solvents,which helped to easily fabricate self-assembly colloidal particles and nanofibers by vapor diffusion method and electrospinning method, respectively. The azobenzene linkages generated by the macromolecular azo coupling reaction also brought photo-responsive properties to the prepared polymers. | Jilei Wang Shang Li Ruiqi Liang Bing Wu Yaning He | 2018 | Chinese Chemical Letters2018，29，1： | 1 |
| 12 | Environmental Science & Technology 显示文摘 | Pei Zhiguo Shah Xiaoquan Wen Bei He Bo Liu Tao Xie Yaning Owens Gary | 2008 | 42(18): 6849-68542008，42，18： | 1 |
| 13 | Fabricating super-hydrophobic lotus-leaf-like surfaces through soft-lithographic imprinting显示文摘 | Liu Bin He Yaning Fan Yin | 2006 | Macromolecular Rapid Commun2006，27，21： | 1 |
| 14 | Azo polymer microspherical cap array: soft-lithographic fabrication and photoinduced shape deformation behavior显示文摘 | LIU Bin HE Yaning FAN Pengwei | 2007 | Langmuir2007，23，11： | 1 |
| 15 | Hydrophilization of Polyurethane Foam Carriers in MBBR with Hyperbranched Polymeric Diazonium Salts显示文摘 | LI Shang WANG Jilei TUO Xinlin HE Yaning | 2018 | Chemical Research in Chinese Universities2018，34，5： | 1 |
| 16 | Fabricating super-hy- drophobic lotus-leaf-like surfaces through soft-lithographic imprinting显示文摘 | Liu Bin He Yaning Fan Yin | 2006 | Macromolecular Rapid Commun2006，27，21： | 1 |
| 17 | Fabricating super-hydrophobic lotus-leaf-like surfaces through soft-lithographic imprinting显示文摘 | Liu Bin He Yaning Fan Yin | | 0，，21： | 1 |
| 18 | Epoxy-based polymers containing methyl-substituted azobenzene chromophores and photoinduced surface relief gratings 显示文摘 | Yaning He Jianjun Yin Pengchao Che | 2006 | European Polymer Journal2006，42，： | 1 |
| 19 | Epoxy-based polymers containing methyl-substituted azobenzene chromophores and photoinduced surface relief gratings 显示文摘 | Yaning He Jianjun Yin Pengchao Che | 2006 | European Polymer Journal2006，42，： | 1 |
| 20 | Surfactant-Modified Hydrophobic Biochar Derived from Laver (Porphyra haitanensis) with Superior Removal Performance for Kitchen Oil显示文摘In this study,a novel absorpent(MSAR600℃)with a hydrophobic surface and hierarchical porous structure for the removal of kitchen oil was facilely fabricated from the macroalgae,laver(Porphyra haitanensis)by incorpor-ating high-temperature carbonization and alkyl polyglucosides(APG)and rhamnolipid(RL)surfactants modifi-cation.The characterization results showed MSAR600℃ possessed a louts-leaf-like papillae microstructure with high contact angle(137.5°),abundant porous structure with high specific surface area(23.4 m^(2)/g),and various oxygen-containing functional groups(-OH,C=O,C-O).Batch adsorption experiments were conducted to inves-tigate the effect of adsorption time,temperature,pH,and absorbent dose on kitchen oil adsorption performance.Then the practical application for the removal of kitchen oil using MSAR600℃ was also performed.The results showed that MSAR600℃ had a higher removal efficiency for kitchen oil(75.98%),compared with the commercial detergent(72.3%).This study demonstrates an example of fabricating a green tableware detergent for enhanced removal performance of kitchen oil. | Jiaxing Sun Lili Ji Qianrui He Ran Li Xiaoyue Xia Yaning Wang Yi Yang Lu Cai Jian Guo | 2023 | Journal of Renewable Materials2023，11，8： | 0 |
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