| 1 | Helicobacter pylori seropositivity in diabetic patients is associated with microalbuminuria显示文摘AIM:To investigate the relationship between Helicobacter pylori(H.pylori) seropositivity and the presence of microalbuminuria.METHODS:Between December 2003 and February 2010,asymptomatic individuals who visited the Seoul National University Healthcare System Gangnam Center for a routine check-up and underwent tests for H.pylori immunoglobulin G antibodies and urinary albumin to creatinine ratio(UACR) were included.All study subjects completed a structured questionnaire,anthropometric measurements and laboratory tests.Anti-H.pylori immunoglobulin G was identified using an enzyme-linked immunosorbent assay kit.A random single-void urine sample,collected using a clean-catch technique,was obtained to determine the UACR.The presence of microalbuminuria was defined as a UACR from 30 to 300 μg/mg.The presence of diabetes mellitus(DM) was defined as either a fasting serum glucose level greater than or equal to 126 mg/dL or taking anti-diabetic medication.Multiple logistic regression analysis was performed to identify the risk factors.The dependent variable was microalbuminuria,and the independent variables were the other study variables.RESULTS:A total of 2716 subjects(male,71.8%;mean age,54.9 years) were included.Among them,224 subjects(8.2%) had microalbuminuria and 324 subjects(11.9%) had been diagnosed with DM.Subjects with microalbuminuria had a significantly higher H.pylori seropositivity rate than subjects without microalbuminuria(60.7% vs 52.8%,P = 0.024).Multivariate analysis after adjustment for age,body mass index(BMI),waist circumference,and glucose and triglyceride levels showed that H.pylori seropositivity was significantly associated with microalbuminuria [odds ratio(OR),1.40,95% CI,1.05-1.89,P = 0.024].After the data were stratified into cohorts by glucose levels(≤ 100 mg/dL,100 mg/dL < glucose < 126 mg/dL,and ≥ 126 mg/dL or history of DM),H.pylori seropositivity was found to be significantly associated with microalbuminuria in diabetic subjects after adjusting for age,BMI and serum creatinine level(OR,2.21,95% CI,1.20-4.08,P = 0.011).In addition,the subjects were divided into five groups.Those without microalbuminuria(an UACR of < 30 μg/mg) were divided into four groups in accordance with their UACR values,and subjects with microalbuminuria comprised their own group.Notably,H.pylori seropositivity gradually increased with an increase in UACR(P = 0.001) and was highest in subjects with microalbuminuria(OR,2.41,95% CI,1.14-5.11).This suggests that H.pylori seropositivity is positively associated with microalbuminuria in diabetic subjects.CONCLUSION:H.pylori seropositivity was independently associated with microalbuminuria,and the prevalence of H.pylori seropositivity was associated with the severity of UACR in diabetic subjects. | Goh Eun Chung Nam Ju Heo Min Jung Park Su Jin Chung Hae Yeon Kang Seung Joo Kang | 2013 | World Journal of Gastroenterology2013,19,1: | 11 |
| 4 | 韩国赤松林龄序列的生物量及碳氮储量显示文摘调查了韩国6种不同林龄(10,27,30,32,44和71年生)赤松林(Pinus densiflora)的生物量、碳含量和氮含量.采用收割法采集30株个体作为样本,其中有12株挖掘了全部的根系,采集植物体地上、地下部分、凋落物(CWD)、地被物及矿质土壤样品(0-30cm)进行分析.结果显示,树木生物量最大的是林龄71年生的样地(202.8t/ha),最小的是林龄10年生的样地(18.4t/ha);林龄71年生样地的矿质土壤碳、氮储量均高于其他样地,这可能与该样地较高的土壤碳、氮密度有关.生态系统总碳、氮储量从林龄10年生的样地(18.8tC/ha和1.3tN/ha)到林龄71年生的样地(201.4tC/ha和8.5tN/ha)逐渐增高.生态系统总碳储量和树木碳储量都呈现出随着林龄S型增长的趋势,而凋落物、地被物和矿质土壤的氮含量则未显示出随林龄变化而显著变化的趋势.本结果对了解赤松林碳、氮储量的现状及预测未来的生长变化提供有效依据. | NOH Nam Jin SON Yowhan LEE Sue Kyoung SEO Kyung Won HEO Su Jin YI Myong-Jong PARK Pil Sun KIM Rae Hyun SON Yeong Mo LEE Kyeong Hak | 2010 | 中国科学:生命科学2010,40,7: | 1 |