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| 1 | Adjuvant chemotherapy for early-stage cervical cancer显示文摘The aim of this review is to address the current status of adjuvant chemotherapy alone in early-stage cervical cancer treatments in the literature. At present, the therapeutic effect of adjuvant chemotherapy alone after radical surgery(RS) has not yet been established, and radiation therapy(RT) or concurrent chemoradiotherapy(CCRT) is recommended as the standard adjuvant therapy after RS for early-stage cervical cancer in various guidelines. The main purpose of adjuvant therapy after RS, however, should be to reduce extrapelvic recurrence rather than local recurrence, although adjuvant RT or CCRT has survival benefits for patients with intermediate- or high-risk factors for recurrence. Moreover, several studies reported that adjuvant therapies including RT were associated with a higher incidence of complications, such as lymphedema, bowel obstruction and urinary disturbance, and a lower grade of long-term quality of life(QOL) or sexual functioning than adjuvant chemotherapy alone. The effect of adjuvant chemotherapy alone for early-stage cervical cancer with intermediate- or high-risk factors for recurrence were not fully investigated in prospective studies, but several retrospective studies suggest that the adjuvant effects of chemotherapy alone are at least similar to that of RT or CCRT in terms of recurrence rate, disease-free survival, or overall survival(OS) with lower incidence of complications. Whereas cisplatin based combination regimens were used in these studies, paclitaxel/cisplatin(TP) regimen, which is currently recognized as a standard chemotherapy regimen for patients with metastatic, recurrent or persistent cervical cancer by Gynecologic Oncology Group(GOG), had also survival benefit as an adjuvant therapy. Therefore, it may be worth considering a prospective randomized controlled trial(RCT) of adjuvant chemotherapy alone using TP regimen versus adjuvant RT as an alternative adjuvant therapy. Because early-stage cervical cancer is a curable condition, it is necessary that the therapeutic strategies should be improved with considering adverse events and QOL for long-term survivors. | Hiroshi Asano Yukiharu Todo Hidemichi Watari | 2016 | Chinese Journal of Cancer Research2016，28，2： | 10 |
| 2 | Relapse of both small cell lung cancer and Lambert-Eaton myasthenic syndrome after a 13-year disease-free survival period显示文摘Lambert-Eaton myasthenic syndrome(LEMS) is a paraneoplastic syndrome and only 3%of small cell lung carcinoma(SCLC) patients have LEMS.Moreover,the recurrence of SCLC after a disease-free survival(DFS) of more than 10 years is rare.We report a patient who had a recurrence of both SCLC and LEMS after a 13-year DFS period.A 69-year-old man was diagnosed with LEMS and SCLC(cT0N2M0,stage ⅢA) 13 years ago.Chemoradiotherapy was performed and a complete response was achieved.With anticancer treatment,the LEMS symptoms was alleviated.At the age of 82 years,gait disturbance appeared followed by left supraclavicular lymphadenopathy and further examination revealed the recurrence of SCLC.Careful screening for the recurrence of SCLC might be needed when the patient has recurrent or secondary paraneoplastic neurological syndrome even after a long DFS period. | Fumio Asano Keisuke Watanabe Masaharu Shinkai Yoshitaka Tei Kei Mishina Mikiko Tanabe Hiroshi Ishii Masahiro Shinoda Tadasuke Shimokawaji Makoto Kudo Takeshi Kaneko | 2016 | Chinese Journal of Cancer2016，35，11： | 3 |
| 3 | Association between hyperglycemia and the no-reflow phenomenon inpatients with acute myocardial infarction显示文摘 | Katsuomi Iwakura Hiroshi Ito Masashi Ikushima Shigeo Kawano Atsushi Okamura Katsuaki Asano Tadashi Kuroda Koji Tanaka Tohru Masuyama Masatsugu Hori Kenshi Fujii | 2003 | Journal of the American College of Cardiology2003，，1： | 2 |
| 4 | Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance显示文摘 | Sizuo Kajiyama Goji Hasegawa Mai Asano Hiroko Hosoda Michiaki Fukui Naoto Nakamura Jo Kitawaki Saeko Imai Koji Nakano Mitsuhiro Ohta Tetsuo Adachi Hiroshi Obayashi Toshikazu Yoshikawa | 2008 | Nutrition Research2008，，3： | 1 |
| 5 | A novel adenovirus expressing human 4–1BB ligand enhances antitumor immunity显示文摘 | Hiroshi Yoshida Yu Katayose Michiaki Unno Masanori Suzuki Hideaki Kodama Shin-ichi Takemura Ryutaro Asano Hiroki Hayashi Kuniharu Yamamoto Seiki Matsuno Toshio Kudo | 2003 | Cancer Immunology Immunotherapy2003，，2： | 1 |
| 6 | Suppression of camptothecin biosynthetic genes results in metabolic modification of secondary products in hairy roots of Ophiorrhiza pumila显示文摘 | Takashi Asano Kanae Kobayashi Emi Kashihara Hiroshi Sudo Ryosuke Sasaki Yoko Iijima Koh Aoki Daisuke Shibata Kazuki Saito Mami Yamazaki | 2013 | Phytochemistry2013，，： | 1 |
| 7 | Highly-Reproducible Preparation of Pb(Zr,Ti) O3 Films at Low Deposition Temperature by Metal Organic Chemical Vapor Deposition显示文摘 | ASANO GOUJI OIKAWA TAKAHIRO FUNAKUBO HIROSHI | 2003 | Jpn J Appl Phys2003，42，： | 1 |
| 8 | Transnasal ERCP/ENBD using an ultrathin esophagogastroduodenoscope显示文摘 | Akihiro Mori Takayuki Asano Takako Maruyama Noritsugu Ohashi Hiroshi Inoue Shodo Takekoshi Masataka Okuno | 2006 | Journal of Gastroenterology2006，，12： | 1 |
| 9 | Effect of solvent on MOCVD of Pb(r,Ti)3 films liquid-delivery source supply method显示文摘 | HIROSHI FUNAKUBO GOUJI ASANO TOMOHIKO OZEKI | 2004 | J Electrochem Soc2004，46，： | 1 |
| 10 | Microgrids:an overview of ongoing research,develoment,and demonstration projects显示文摘 | Hatziargyriou Nikos Asano Hiroshi Iravani Reza | 2007 | IEEE Power and Energy Magazine2007，5，4： | 1 |
| 11 | Transnasal ERCP/ENBD using an ultrathin esophagogastroduodenoscope显示文摘 | Akihiro Mori Takayuki Asano Takako Maruyama Noritsugu Ohashi Hiroshi Inoue Shodo Takekoshi Masataka Okuno | 2006 | Journal of Gastroenterology2006，，12： | 1 |
| 12 | Microgrids显示文摘 | NIKOS Hatziargyrious HIROSHI Asano REZA Iravani | 2007 | IEEE Power and Energy Magazine2007，5，4： | 1 |
| 13 | Policymaking for microgrids显示文摘 | Chris Mamay Hiroshi Asano Stavros Papathanassiou | 2008 | IEEE Power and Ener- gy Magazine2008，6，3： | 1 |
| 14 | Microgrids显示文摘 | Nikos Hatziargyriou Hiroshi Asano Reza Iravani | 2007 | IEEE Power & Energy Magazine2007，78，： | 1 |
| 15 | An Overview of On-going Research,Development,and Demonstration Projects显示文摘 | Nikos Hatziargyriou Hiroshi Asano | | 0，，： | 1 |
| 16 | Mierogrids显示文摘 | Hatziargyriou Nikos Asano Hiroshi Iravani Reza | 2007 | IEEE Power and Energy Magazine2007，5，4： | 1 |
| 17 | Microgrids: An Overview of Ongoing Research, Development, and Demonstra- tion Projects显示文摘 | Nikos Hatziargyriou Hiroshi Asano Reza Iravani | 2007 | IEEE power and energy magazine2007，2007，： | 1 |
| 18 | Neuroprotective Effect of an Antioxidant, Ebselen, in Patients with Delayed Neurological Deficits after Aneurysmal Subarachnoid Hemorrhage显示文摘 | Isamu Saito Takao Asano Keiji Sano Kintomo Takakura Hiroshi Abe Takashi Yoshimoto Haruhiko Kikuchi Tomio Ohta Sadahiko Ishibashi | 1998 | Neurosurgery1998，，2： | 1 |
| 19 | New prognostic factor influencing long-term survival of patients with advanced gallbladder carcinoma显示文摘 | Fumihiko Miura Takehide Asano Hodaka Amano Naoyuki Toyota Keita Wada Kenichiro Kato Tadahiro Takada Hiroshi Takami Gaku Ohira Hisahiro Matsubara | 2010 | Surgery2010，，2： | 1 |
| 20 | A mutated superantigen SEA D227A fusion diabody specific to MUC1 and CD3 in targeted cancer immunotherapy for bile duct carcinoma显示文摘 | Shin-ichi Takemura Toshio Kudo Ryutaro Asano Masanori Suzuki Kouhei Tsumoto Naoki Sakurai Yu Katayose Hideaki Kodama Hiroshi Yoshida Shinji Ebara Hisaaki Saeki Kohzoh Imai Seiki Matsuno Izumi Kumagai | 2002 | Cancer ImmunologyImmunotherapy2002，，1： | 1 |
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