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| 1 | Evaluation of the Xpert MTB/RIF assay for diagnosis of tuberculosis and rifampin resistance in county-level laboratories in Hunan province, China显示文摘 | Hu Peilei Bai Liqiong Liu Fengping Ou Xichao Zhang Zhiying Yi Songlin Chen Zhongnan Gong Daofang Liu Binbin Guo Jingwei Tan Yunhong | 2014 | Chinese Medical Journal2014，，21： | 24 |
| 2 | MiR-139-5p inhibits migration and invasion of colorectal cancer by downregulating AMFR and NOTCH1显示文摘MicroRNAs (miRNAs ) 由抑制最近在 carcinogenesis 和转移在我们 non-protein-coding RNA 的角色的理解带给卓见的 posttranscriptional 施加功能。在这研究,我们在 CRC 在 colorectal 癌症(CRC ) 和它的潜在的临床的应用程序描述了函数和 miR-139-5p 的分子的机制。我们发现 miR-139-5p 是显著地, CRC 与邻近的 noncancerous 纸巾(NCT ) 相比取样的在 73.8% 的 downregulated,和减少的 miR-139-5p 与穷人被联系预后。功能的分析证明 miR-139-5p 的那个宫外的表达式在 vivo 在 vitro 和转移压制了 CRC 房间移植和侵略。机械学的调查表明 miR-139-5p 由指向 AMFR 和 NOTCH1 压制 CRC 房间侵略和转移。二基因 phenocopied 击倒 CRC 上的 miR-139-5p 的禁止的效果转移。而且,二基因的蛋白质层次与 NCT 相比是在 CRC 样品的 upregulated,并且相反地与 miR-139-5p 表示相关。增加的 NOTCH1 蛋白质表示与 CRC 病人的差的预后被相关。一起,我们的数据显示 miR-139-5p 为 CRC 是潜在的肿瘤 suppressor 和预示的因素,并且指向 miR-139-5p 可以镇压 CRC 的转移并且改善幸存。 | Mingxu Song Yuan Yin Jiwei Zhang Binbin Zhang Zehua Bian Chao Quan Leyuan Zhou Yaling Hu Qifeng Wang Shujuan Ni Bojian Fei Weili Wang Xiang Du Dong Hua Zhaohui Huang | 2014 | Protein & Cell2014，5，11： | 14 |
| 3 | Magnetohydrodynamics (MHD) numerical simulations on the interaction of the solar wind with the magnetosphere: A review显示文摘The magnetosphere is the outermost layer of the geospace, and the interaction of the solar wind with the magnetosphere is the key element of the space weather cause-and-effect chain process from the Sun to Earth, which is one of the most challenging scientific problems in the geospace weather study. The nonlinearity, multiple component, and time-dependent nature of the geospace make it very difficult to describe the physical process in geospace using traditional analytic analysis approach. Numerical simulations, a new research tool developed in recent decades, have a deep impact on the theory and application of the geospace. MHD simulations started at the end of the 1970s, and the initial study was limited to two-dimensional (2D) cases. Due to the intrinsic three-dimensional (3D) characteristics of the geospace, 3D MHD simulations emerged in the 1980s, in an attempt to model the large-scale structures and fundamental physical processes in the magnetosphere. They started to combine with the space exploration missions in the 1990s and make comparisons with observations. Physics-based space weather forecast models started to be developed in the 21st century. Currently only a few space-power countries such as USA and Japan have developed 3D magnetospheric MHD models. With the rapid advance of space science in China, we have developed a new global MHD model, namely PPMLR-MHD, which has high order spatial accuracy and low numerical dissipation. In this review, we will briefly introduce the global 3D MHD modeling, especially the PPMLR-MHD code, and summarize our recent work based on the PPMLR-MHD model, with an emphasis on the interaction of interplanetary shocks with the magnetosphere, large-scale current systems, reconnection voltage and transpolar potential drop, and Kelvin-Helmholtz (K-H) instability at the magnetopause. | WANG Chi GUO XiaoCheng PENG Zhong TANG BinBin SUN TianRan LI WenYa HU YouQiu | 2013 | Science China Earth Sciences2013，56，7： | 10 |
| 4 | Ethylene oligomerization by novel iron(Ⅱ) diimine complexes/MAO显示文摘Two novel Fe(Ⅱ) diimine complexes have been synthesized. In combination with MAO, they generate active catalytic systems that oligomerize ethylene with both high catalytic activity and high selectivity for a-olefins. The effects of substituents on the aryl ring, reaction temperatures and molar ratios of Al/Fe on catalytic activity and product distribution are studied. | WANG Hang, YAN Weidong, JIANG Tao, LIU Binbin, XU Wenqing, MA Jianjiang & HU YouliangState Key Laboratory of Engineering Plastics, Center for Molecular Science, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China Graduate Student of | 2002 | Chinese Science Bulletin2002，47，19： | 8 |
| 5 | Reconstruction of a hybrid nucleoside antibiotic gene cluster based on scarless modification of large DNA fragments显示文摘Genetic modification of large DNA fragments(gene clusters) is of great importance in synthetic biology and combinatorial biosynthesis as it facilitates rational design and modification of natural products to increase their value and productivity.In this study,we developed a method for scarless and precise modification of large gene clusters by using RecET/RED-mediated polymerase chain reaction(PCR) targeting combined with Gibson assembly.In this strategy,the biosynthetic genes for peptidyl moieties(HPHT) in the nikkomycin biosynthetic gene cluster were replaced with those for carbamoylpolyoxamic acid(CPOAA)from the polyoxin biosynthetic gene cluster to generate a^40 kb hybrid gene cluster in Escherichia coli with a reusable targeting cassette.The reconstructed cluster was introduced into Streptomyces lividans TK23 for heterologous expression and the expected hybrid antibiotic,polynik A,was obtained and verified.This study provides an efficient strategy for gene cluster reconstruction and modification that could be applied in synthetic biology and combinatory biosynthesis to synthesize novel bioactive metabolites or to improve antibiotic production. | Jiming Zhuo Binbin Ma Jingjing Xu Weihong Hu Jihui Zhang Huarong Tan Yuqing Tian | 2017 | Science China(Life Sciences)2017，60，9： | 6 |
| 6 | Imposing Active Sources during High-Frequency Passive Surface-Wave Measurement显示文摘 | Feng Cheng Jianghai Xia Chao Shen Yue Hu Zongbo Xu Binbin Mi | 2018 | Engineering2018，4，5： | 3 |
| 7 | Synthesis and characterization of BiFeO_3 nanotube arrays and Y-junction BiFeO_3 nanotubes显示文摘Multiferroic BiFeO3 (BFO) nanotube arrays (~100 nm in diameter and ~50 μm in length) were synthesized by the sol-gel method utilizing the anodic aluminum oxide (AAO) membrane technique. The micro-structure and chemical components of the BFO nanotubes were investigated using scanning electron microscopy (SEM), transmission electron microscopy (TEM) and X-ray photoelectron spectrometer (XPS). The BFO nanotubes exhibited polycrystalline microstructures. The novel Y-junction BFO nano-tubes were simultaneously fabricated. | LI ChunYang LIU Bing ZHAO JianPo WANG JiangFeng HU BinBin DU ZuLiang | 2009 | Chinese Science Bulletin2009，54，5： | 3 |
| 8 | Enhanced Potassium‑Ion Storage of the 3D Carbon Superstructure by Manipulating the Nitrogen‑Doped Species and Morphology显示文摘Potassium-ion batteries(PIBs)are attractive for gridscale energy storage due to the abundant potassium resource and high energy density.The key to achieving high-performance and large-scale energy storage technology lies in seeking eco-efficient synthetic processes to the design of suitable anode materials.Herein,a spherical sponge-like carbon superstructure(NCS)assembled by 2D nanosheets is rationally and efficiently designed for K+storage.The optimized NCS electrode exhibits an outstanding rate capability,high reversible specific capacity(250 mAh g^(−1) at 200 mA g^(−1) after 300 cycles),and promising cycling performance(205 mAh g^(−1) at 1000 mA g^(−1) after 2000 cycles).The superior performance can be attributed to the unique robust spherical structure and 3D electrical transfer network together with nitrogen-rich nanosheets.Moreover,the regulation of the nitrogen doping types and morphology of NCS-5 is also discussed in detail based on the experiments results and density functional theory calculations.This strategy for manipulating the structure and properties of 3D materials is expected to meet the grand challenges for advanced carbon materials as high-performance PIB anodes in practical applications. | Yanhua Li Kui Xiao Cong Huang Jin Wang Ming Gao Aiping Hu Qunli Tang Binbin Fan Yali Xu Xiaohua Chen | 2021 | Nano-Micro Letters2021，13，1： | 2 |
| 9 | Drug-loaded balloon with built-in NIR controlled tip-separable microneedles for long-effective arteriosclerosis treatment显示文摘Drug-eluting balloon(DEB)angioplasty has emerged as an effective treatment for cardiovascular and cerebrovascular diseases.However,distal embolism and late lumen restenosis could be caused by drug loss during DEB handling and rapid drug metabolization.Here,a drug-loaded balloon equipped with tip-separable microneedles on the balloon surface(MNDLB)was developed.Inbuilt near-infrared(NIR)ring laser inside the catheter inner shaft was introduced to activate the biodegradable microneedle tips for the first time.The drug-loaded tips thus could be embedded in the vasculature and then released antiproliferative drug-paclitaxel slowly via polymer degradation for more than half a year.A significant increase in drug delivery efficiency and superior therapeutic effectiveness compared with the standard DEB were demonstrated using an atherosclerosis rabbit model. | Li Huang Huaqiang Fang Teng Zhang Binbin Hu Shichen Liu Fanzhen Lv Zhaoxia Zeng Huijie Liu Weimin Zhou Xiaolei Wang | 2023 | Bioactive Materials2023，，5： | 2 |
| 10 | Development of an n -heptane- n -butanol-PAH mechanism and its application for combustion and soot prediction显示文摘 | Hu Wang Rolf Deneys Reitz Mingfa Yao Binbin Yang Qi Jiao Lu Qiu | 2012 | Combustion and Flame2012，，： | 2 |
| 11 | Polymorphisms in genes of APE1 , PARP1 , and XRCC1 : risk and prognosis of colorectal cancer in a Northeast Chinese population显示文摘 | Ye Li Shuying Li Zhiwei Wu Fulan Hu Lin Zhu Xiaojuan Zhao Binbin Cui Xinshu Dong Suli Tian Fan Wang Yashuang Zhao | 2013 | Medical Oncology2013，，2： | 1 |
| 12 | The prognostic significance of polymorphisms in hMLH1/hMSH2 for colorectal cancer显示文摘 | Yibaina Wang Guangxiao Li Fulan Hu Haoran Bi Zhiwei Wu Xiaojuan Zhao Ye Li Shuying Li Dandan Li Binbin Cui Xinshu Dong Yashuang Zhao | 2014 | Medical Oncology2014，，6： | 1 |
| 13 | Functionalization of multi-walled carbon nanotubes using diamines显示文摘 | ZHANG Binbin SHEN Jianfeng HU Yizhe ct al | 2008 | Journal of Fudan University: Natural Science2008，47，4： | 1 |
| 14 | Correction to:MiR-139-5p inhibits migration and invasion of colorectal cancer by downregulating AMFR and NOTCH1显示文摘CORRECTION TO:PROTEIN CELL(2014)5(11):851-861 http://gffzzd3cc09b8251d45dfo0vo09u6xfbou66qv.ffgz.tsg.suse.edu.cn/10.1007/S13238-014-0093-5 In the original publication the display of Fig.1 is in correct.The correct Fig.1 is available in this correction. | Mingxu Song Yuan Yin Jiwei Zhang Binbin Zhang Zehua Bian Chao Quan Leyuan Zhou Yaiing Hu Qifeng Wang Shujuan Ni Bojian Fei Weiii Wang Xiang Du Dong Hua Zhaohui Huang | 2021 | Protein & Cell2021，12，8： | 1 |
| 15 | Soft,stretchable,wireless intelligent three-lead electrocardiograph monitors with feedback functions for warning of potential heart attack显示文摘Cardiovascular diseases(CVDs)are fatal chronic diseases,where electrocardiography(ECG)monitoring could be a prominent solution for early diagnosis.In spite of available commercialized,multilead ECG devices,bulky formats,discontinuous monitoring,and no safety alarm system significantly limit their practical applications.Herein,we present a soft,and stretchable,three-lead ECG device allowing continuous monitoring and wireless transmission of ECG signals.A newly developed organohydrogel patch with a strong adhesive ability(~9.9 kPa)and higher conductivity(~6.5 kΩ)is applied for high-quality ECG signals collection.With a long operation duration(6.5 h)and wireless transmission distance(20.9 m),it could fulfill most of the daily applications.Machine learning algorithms and the graphical user interface are used for real-time ECG monitoring and cardiac abnormalities diagnosis.The vibratory flexible actuator,which is triggered by cardiac abnormalities that need immediate medical treatment,is also integrated as a warning system for the user.As a newly reported stretchable multi-lead ECG device for long-term ECG signal monitoring,there is a high potential for improving users'life quality with the high-risk population of CVDs. | Chunki Yiu Yiming Liu Chao Zhang Jingkun Zhou Huiling Jia Tsz H.Wong Xingcan Huang Jian Li Kuanming Yao Ming K.Yau Ling Zhao Hu Li Binbin Zhang Wooyoung Park Yuanting Zhang Zuankai Wang Xinge Yu | 2022 | SmartMat2022，3，4： | 1 |
| 16 | High-performance solutions of geographically weighted regression in R显示文摘As an established spatial analytical tool,Geographically Weighted Regression(GWR)has been applied across a variety of disciplines.However,its usage can be challenging for large datasets,which are increasingly prevalent in today’s digital world.In this study,we propose two high-performance R solutions for GWR via Multi-core Parallel(MP)and Compute Unified Device Architecture(CUDA)techniques,respectively GWR-MP and GWR-CUDA.We compared GWR-MP and GWR-CUDA with three existing solutions available in Geographically Weighted Models(GWmodel),Multi-scale GWR(MGWR)and Fast GWR(FastGWR).Results showed that all five solutions perform differently across varying sample sizes,with no single solution a clear winner in terms of computational efficiency.Specifically,solutions given in GWmodel and MGWR provided acceptable computational costs for GWR studies with a relatively small sample size.For a large sample size,GWR-MP and FastGWR provided coherent solutions on a Personal Computer(PC)with a common multi-core configuration,GWR-MP provided more efficient computing capacity for each core or thread than FastGWR.For cases when the sample size was very large,and for these cases only,GWR-CUDA provided the most efficient solution,but should note its I/O cost with small samples.In summary,GWR-MP and GWR-CUDA provided complementary high-performance R solutions to existing ones,where for certain data-rich GWR studies,they should be preferred. | Binbin Lu Yigong Hu Daisuke Murakami Chris Brunsdon Alexis Comber Martin Charlton Paul Harris | 2022 | Geo-Spatial Information Science2022，25，4： | 1 |
| 17 | Numerical prediction of the interaction noise radiated from an axial fan显示文摘 | HU Binbin OUYANG Hua WU Yadong | 2013 | Applied Acoustics2013，74，4： | 1 |
| 18 | Enhanced photocatalytic CO_(2) hydrogenation with wide-spectrum utilization over black TiO_(2) supported catalyst显示文摘Light-driven conversion of CO_(2)into chemicals/fuels is a desirable approach for achieving carbon neutral-ity using clean and sustainable energy.However,its scale-up application is restricted due to insufficient efficiency.Herein,we present a photothermal catalytic hydrogenation of CO_(2)into CH_(4)over Ru/black TiO_(2) catalysts,aiming to achieve the synergistic use of light and heat in solar energy during CO_(2)conversion.Owing to the desirable spectral response ability and photothermal conversion performance of black TiO_(2),an efficient combination of photocatalysis and thermocatalysis has been established.The CO_(2)hydrogena-tion was significantly accelerated because of the increased catalyst surface temperature enabled by the photothermal effect of black TiO_(2).Simultaneously,through the in situ X-ray photoelectron spectroscopy(XPS)observation,electron-rich Ru nanoparticles was achieved based on the photo-induced excitation,thereby providing more negative hydride to improve nucleophilic attack to the CO_(2),obtaining the CH_(4) yield of 93.8%. | Binbin Jin Xin Ye Heng Zhong Fangming Jin Yun Hang Hu | 2022 | Chinese Chemical Letters2022，33，2： | 1 |
| 19 | Hydrothermalsynthesis and magnetic properties of single-crystallineBiFe03 nanowires 显示文摘 | LIU Bing HU Binbin DU Zuliang | 2011 | Chemical Communications2011，47，： | 1 |
| 20 | Numerical prediction of the interaction noise radiated from an axial fan显示文摘 | HU Binbin OUYANG Hua WU Yadong | 2013 | Applied Acoustic2013，74，4： | 1 |
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