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| 1 | Analysis of extrapolation cascadic multigrid method(EXCMG)显示文摘Based on an asymptotic expansion of finite element,a new extrapolation formula and extrapolation cascadic multigrid method(EXCMG)are proposed,in which the new extrapolation and quadratic interpolation are used to provide a better initial value on refined grid.In the case of triple grids,the error of the new initial value is analyzed in detail.A larger scale computation is completed in PC. | CHEN ChuanMiao HU HongLing XIE ZiQing LI ChenLiang | 2008 | Science China Mathematics2008，51，8： | 23 |
| 2 | Effect of electroacupuncture on brain-derived neurotrophic factor mRNA expression in mouse hippocampus following cerebral ischemia-reperfusion injury显示文摘OBJECTIVE:This work aims to observe the effects of electroacupuncture on brain-derived neurotrophic factor(BDNF) mRNA expression in mouse hippocampus following cerebral ischemia-reperfusion injury.METHODS:The models of mouse cerebral ischemia-reperfusion injury were established.A total of 96 healthy mice were randomly assigned into 4 groups,namely,the sham surgery,model,model + electroacupuncture,and mode + hydergine groups.Mice in the model + electroacupuncture group were treated through electroacupuncture at the Shenshu(BL 23),Geshu(BL 17),and Baihui(GV 20) acupoints.Mice in the model+hydergine group were intragastrically administered with hydergine(0.77 mg/kg-1 · day-1).The levels of BDNF mRNA expressions in the hippocampus were analyzed through a semi-quantitative reverse transcription-polymerase chain reaction assay on days 1 and 7 after the surgeries.RESULTS:BDNF mRNA expressions in the mouse hippocampus of the model group on days 1 and 7 after the surgery were higher than those of the sham surgery group(both P<0.01).On days 1 and 7 of the electroacupuncture treatment,BDNF mRNA expression in the mouse hippocampus of the model + electroacupuncture group was significantly elevated compared with the model group(both P< 0.01) or the model + hydergine group(both P< 0.01).On days 1 and 7 of the hydergine treatment,BDNF mRNA expression in the mouse hippocampus of the model + hydergine group tended to increase compared with the model group;however,statistical significance was not achieved(both P> 0.05).CONCLUSION:Electroacupuncture treatment enhances endogenous BDNF expression,which may improve the survival environment for intracerebral neurons and inhibit the apoptosis of hippocampal cells. | Jianxin Zhao Huazhou Xu Yuanxiang Tian Manxiang Hu Hongling Xiao | 2013 | Journal of Traditional Chinese Medicine2013，33，2： | 14 |
| 3 | Pediatric reference intervals in China(PRINCE):design and rationale for a large,multicenter collaborative cross-sectional study显示文摘There is a lack of accurate pediatric reference intervals(RIs) in China, with most commonly used RIs established without consideration of the effect of age and gender. The Pediatric Reference Intervals in China(PRINCE) project aims to establish and verify pediatric RIs for 31 common laboratory measurands.The project will be a large, multicenter cross-sectional study:14,490 healthy children and adolescents aged up to 19 years will be surveyed by 10 children's hospitals and one pediatric department of a university hospital. To evaluate the feasibility and efficiency of the study methods, 602 children were surveyed in the pilot phase of the PRINCE study in April 2017: it found that some measurands were distinctly age dependent and that there were differences between values for males and females. The results of the pilot study affirmed the necessity of the PRINCE project for Chinese pediatrics. The pilot also indicated potential difficulties in the full survey, e.g., difficulties in recruiting children aged under 3 years and insufficient collection of blood samples from infants. The operation of the PRINCE project has been modified based on the findings in the pilot study toward improving the validity of the PRINCE project and promoting its openness and transparency. | Xin Ni Wenqi Song Xiaoxia Peng Ying Shen Yaguang Peng Qiliang Li Yan Wang Lixin Hu Yanying Cai Hong Shang Min Zhao Hong Jiang Yaoguo Huang Runqing Mu Wenxiang Chen Mingting Peng Chuanbao Zhang Jie Zeng Chenbin Li Hongling Yang Yongmei Jiang Jin Xu Guixia Li Hongbing Chen Yun Xiang Sancheng Cao Zhenxin Guo Dapeng Chen | 2018 | Science Bulletin2018，63，24： | 12 |
| 4 | Analyses of trends and causes for variations in runoff and sediment load of the Yellow River显示文摘Due to the impacts of globe climate change and human activities,dramatic variations in runoff and sediment load were observed for the Yellow River.Analyses of nearly 65 years' data measured at main hydrologic-stations on the Yellow River from 1950 to 2014 indicated that,except for the Tangnaihai station in the head region,sharp downward trends existed in both the annual runoff and annual sediment load according to the Mann-Kendal trend test;and their abrupt changes occurred in 1986 and in1980,respectively,according to the rank sum test.Factors affecting the changes in the runoff and sediment load were very complicated.Results indicated that the reducing precipitation and the increasing water consumption were the main causes for the runoff decline,while the impoundment of the Longyangxia Reservoir and its combined operation with the Liujiaxia Reservoir exerted a direct bearing on the abrupt change in the annual runoff.In addition to the sediment load decrease associated with the runoff reduction,the reduced storm intensity,the conducted soil erosion control,and the constructed dam buildings all played an important role in the trends and abrupt changes of sediment load decline. | Hongling Shi Chunhong Hu Yangui Wang Cheng Liu Huimei Li | 2017 | International Journal of Sediment Research2017，32，2： | 11 |
| 5 | ON EXTRAPOLATION CASCADIC MULTIGRID METHOD显示文摘 | Chuanmiao Chen Zhong-Ci Shi Hongling Hu | 2011 | Journal of Computational Mathematics2011，29，6： | 11 |
| 6 | Reproductive toxicity of organic extracts from petrochemical plant effluents discharged to the Yangtze River,China显示文摘Water pollution of the Yangtze River in China became one of challenges that the government is facing today.Increasing numbers of petrochemical plants were built along the river in past decades,and numbers of organic chemicals were discharged into the river.Our goal was to establish in vitro system on rat sertoli cells,spermatogenic cells and leydig cells to investigate the reproductive toxicity potential induced by organic extracts from petrochemical effluents.Our results showed that the organic extract depressed the viability(p<0.01) and destroyed the plasma membrane integrity of sertoli cells and spermatogenic cells to a certain degree.Accordingly,proportion of early apoptotic sertoli cells and late apoptotic spermatogenic cells increased significantly.Although significant morphological changes were not detected for leydig cells,the extract was observed to inhibit their testosterone production(p<0.01).Sertoli cells and spermatogenic cells appeared to be more sensitive and maybe the main targets of the key toxins.These results suggested that the in vitro system on rat testicular cells may be useful to predicate reproductive toxicity potential of organic extracts from petrochemical effluents.More attention should be paid to the petrochemical effluents,because long-term accumulation of these organic compounds in organisms may cause spermatogenesis malfunction and testosterone reduction. | Xiaoyi Wang Wei Shi Jiang Wu Yingqun Hao Guanjiu Hu Hongling Liu Xiaodong Han Hongxia Yu | 2010 | Journal of Environmental Sciences2010，22，2： | 7 |
| 7 | Guiding T lymphopoiesis from pluripotent stem cells by defined transcription factors显示文摘Achievement of immunocompetent and therapeutic T lymphopoiesis from pluripotent stem cells(PSCs)is a central aim in T cell regenerative medicine.To date,preferentially reconstituting T lymphopoiesis in vivo from PSCs remains a practical challenge.Here we documented that synergistic and transient expression of Runx1 and Hoxa9 restricted in the time window of endothelial-to-hematopoietic transition and hematopoietic maturation stages in a PSC differentiation scheme(iR9-PSC)in vitro induced preferential generation of engraftable hematopoietic progenitors capable of homing to thymus and developing into mature T cells in primary and secondary immunodeficient recipients.Single-cell transcriptome and functional analyses illustrated the cellular trajectory of T lineage induction from PSCs,unveiling the T-lineage specification determined at as early as hemogenic endothelial cell stage and identifying the bona fide pre-thymic progenitors.The induced T cells distributed normally in central and peripheral lymphoid organs and exhibited abundant TCRαβrepertoire.The regenerative T lymphopoiesis restored immune surveillance in immunodeficient mice.Furthermore,gene-edited iR9-PSCs produced tumor-specific T cells in vivo that effectively eradicated tumor cells.This study provides insight into universal generation of functional and therapeutic T cells from the unlimited and editable PSC source. | Rongqun Guo Fangxiao Hu Qitong Weng Cui Lv Hongling Wu Lijuan Liu Zongcheng Li Yang Zeng Zhijie Bai Mengyun Zhang Yuting Liu Xiaofei Liu Chengxiang Xia Tongjie Wang Peiqing Zhou Kaitao Wang Yong Dong Yuxuan Luo Xiangzhong Zhang Yuxian Guan Yang Geng Juan Du Yangqiu Li Yu Lan Jiekai Chen Bing Liu Jinyong Wang | 2020 | Cell Research2020，30，1： | 7 |
| 8 | Controlled growth and photoconductive properties of hexagonal SnS2 nanoflakes with mesa-shaped atomic steps显示文摘We demonstrated the controlled growth of two-dimensional (2D) hexagonal tin disulfide (SnS2) nanoflakes with stacked monolayer atomic steps. The morphology was similar to flat-topped and step-sided mesa plateaus or step pyramids. The SnS2 nanoflakes were grown on mica substrates via an atmospheric-pressure chemical vapor deposition process using tin monosulfide and sulfur powder as precursors. Atomic force microscopy (AFM), electron microscopy, and Raman characterizations were performed to investigate the structural features, and a sequential layer-wise epitaxial growth mechanism was revealed. In addition, systematic Raman characterizations were performed on individual SnS2 nanoflakes with a wide range of thicknesses (1-100 nm), indicating that the A1g peak intensity and Raman shifts were closely related to the thickness of the SnS2 nanoflakes. Moreover, photoconductive AFM was performed on the monolayer-stepped SnS2 nanoflakes, revealing that the flat surface and the edges of the SnS2 atomic steps had different electrical conductive properties and photoconductive behaviors. This is ascribed to the dangling bonds and defects at the atomic step edges, which caused a height difference of the Schottky barriers formed at the interfaces between the PtIr-coated AFM tip and the step edges or the flat surface of the SnS2 nanoflakes. The 2D SnS2 crystals with regular monolayer atomic steps and fast photoresponsivity are promising for novel applications in photodetectors and integrated optoelectronic circuits. | Yi Hu Tao Chen Xiaoqi Wang Lianbo Ma Renpeng Chen Hongfei Zhu Xin Yuan Changzeng Yan Guoyin Zhu Hongling Lv Jia Liang Zhong Jin Jie Liu | 2017 | Nano Research2017，10，4： | 5 |
| 9 | 中国大陆地区的3.5亚系PRRSV起源于中国台湾地区的3.2亚系显示文摘猪繁殖与呼吸综合征病毒(Porcine reproductive and respiratory syndrome virus,PRRSV)是引起猪繁殖与呼吸综合征(PRRS)的病原,该病毒分为两个基因型,以LV 株为代表的欧洲型(基因1型)和以VR2332 株为代表的美洲型(基因2型)。根据ORF5基因,基因2型PRRSV被划分为9个系,目前,在中国已检测到5个系,包括1,3,5,8和9 系。1998年,中国台湾报道首株3系PRRSVMD-001。 | Zhang WenLi Zhang HongL iang Hu Xu | 2019 | 中国预防兽医学报2019，41，8： | 4 |
| 10 | Extrapolation cascadic multigrid method on piecewise uniform grid显示文摘The triangular linear fnite elements on piecewise uniform grid for an elliptic problem in convex polygonal domain are discussed.Global superconvergence in discrete H1-norm and global extrapolation in discrete L2-norm are proved.Based on these global estimates the conjugate gradient method(CG)is efective,which is applied to extrapolation cascadic multigrid method(EXCMG).The numerical experiments show that EXCMG is of the global higher accuracy for both function and gradient. | CHEN ChuanMiao HU HongLing | 2013 | Science China Mathematics2013，56，12： | 3 |
| 11 | TIME-EXTRAPOLATION ALGORITHM (TEA) FOR LINEAR PARABOLIC PROBLEMS显示文摘伪制服上的 Crank-Nicolson 计划的快答案协调因为寓言的问题被讨论。到答案的减少整齐要求,首先,一些新错误估计被证明。第二,我们分析寓言的分离计划的二个特征,并且发现 Multigrid 方法(MG ) 的效率极大地被减少。数字实验比较效率直接结合坡度方法(DCG ) 和推测 Cascadic Multigrid 方法(EXCMG ) 。最后,我们建议一个时间推测算法(茶) ,它作为好起始的价值拿以前的几个水平答案的线性联合加速集中的率。一些典型推测公式数字地被比较。并且我们发现在某些精确性要求下面,为 3 顺序和 7 水平推测公式的 CG 重复计数关于 DCG 的的 1/3。因为 TEA 算法独立于空间尺寸,它为伪制服网孔仍然是有效的。当仅仅最好的格子被需要,建议方法被考虑为非线性的寓言的问题很有效。[从作者抽象] | Hongling Hu Chuanmiao Chen Kejia Pan | 2014 | Journal of Computational Mathematics2014，32，2： | 2 |
| 12 | Flotation performance of a novel Gemini collector for kaolinite at low temperature显示文摘How to sustainably produce bauxite by effective reverse froth flotation of kaolinite at low temperature is an urgent problem to be solved in the field of mineral processing.In this work,a novel amino-based Gemini surfactant butadiyl-1,4-bis(dimethyl dodecylammonium bromide)(BBDB) was prepared and first utilized as a novel collector for kaolinite flotation.Its flotation performance for kaolinite was compared with that of the common monomolecular surfactant 1-dodecylamine(DDA) by micro-flotation tests.The tests results indicated that 95% kaolinite recovery was obtained using 2.0×10^(-4) mol/L BBDB at 25℃ which was half of the dosage when DDA obtained the maximum kaolinite recovery of81%.At extremely low temperature(0℃),3.0×10^(-4) mol/L BBDB could still collect 91% kaolinite,while DDA showed a frustrating ability.The contact angle tests indicated that BBDB could still significantly improve the hydrophobicity of the kaolinite surface(contact angle 71.7°) than DDA(contact angle only25.8°) at 0℃.The Krafft point comparison tests indicated that BBDB had a much lower Krafft point(below0℃) than DDA.Fourier transform infrared spectroscopy(FTIR)-spectrum analysis and zeta potential measurements showed that BBDB was physically adsorbed on the surface of kaolinite through electrostatic interaction. | Shiyong Zhang Zhiqiang Huang Hongling Wang Rukuan Liu Chen Cheng Shuyi Shuai Yajing Hu Zhiqun Guo Xinyang Yu Guichun He Weng Fu | 2021 | International Journal of Mining Science and Technology2021，31，6： | 2 |
| 13 | MOCVD-grown high-mobility Al 0.3 Ga 0.7 N/AlN/GaN HEMT structure on sapphire substrate显示文摘 | Xiaoliang Wang Cuimei Wang Guoxin Hu Hongling Xiao Cebao Fang Junxi Wang Junxue Ran Jianping Li Jinmin Li Zhanguo Wang | 2006 | Journal of Crystal Growth2006，，： | 2 |
| 14 | Asymptotic expansions of finite element solutions to Robin problems in H^3 and their application in extrapolation cascadic multigrid method显示文摘For the Poisson equation with Robin boundary conditions,by using a few techniques such as orthogonal expansion(M-type),separation of the main part and the finite element projection,we prove for the first time that the asymptotic error expansions of bilinear finite element have the accuracy of O(h3)for u∈H3.Based on the obtained asymptotic error expansions for linear finite elements,extrapolation cascadic multigrid method(EXCMG)can be used to solve Robin problems effectively.Furthermore,by virtue of Richardson not only the accuracy of the approximation is improved,but also a posteriori error estimation is obtained.Finally,some numerical experiments that confirm the theoretical analysis are presented. | HU HongLing CHEN ChuanMiao PAN KeJia | 2014 | Science China Mathematics2014，57，4： | 1 |
| 15 | Preparation and luminescence properties of YAG:Ce phosphor for white LED application via a vacuum sintering method显示文摘 | Hongling Shi Jian Chen Jiquan Huang Qianqian Hu Zhonghua Deng Yongge Cao Xuanyi Yuan | 2014 | Phys. Status Solidi A2014，，7： | 1 |
| 16 | Liver spleen on diarrhea type irritable bowel syndrome colonic mucosa of rats 5-HT,the effects of CGRP expression显示文摘 | Liu Jieming Li Hongling Hu Hao | 2011 | Chinese Journal of Experimental Formulas of Chinese Medicine2011，，14： | 1 |
| 17 | Efficient reduction and adsorption of Cr(Ⅵ)using FeCl_(3)-modified biochar:Synergistic roles of persistent free radicals and Fe(Ⅱ)显示文摘Transition metal iron and persistent free radicals(PFRs)both affect the redox properties of biochar,but the electron transfer relationship between them and the coupling reduction mechanism of Cr(Ⅵ)requires further investigation.To untangle the interplay between iron and PFRs in biochar and the infuences on redox properties,FeCl_(3)-modified rice husk biochar(FBCs)was prepared and its reduction mechanism for Cr(Ⅵ)without light was evaluated.The FBCs had higher surface positive charges,oxygen-containing functional groups,and PFRs compared with pristine rice husk biochar(BC).Phenoxyl PFRs with high electrondonating capability formed in biochar.The pronounced electron paramagnetic resonance signals showed that the PFRs preferred to form at lower Fe(Ⅲ)concentrations.While a high concentration of Fe(Ⅲ)would be reduced to Fe(Ⅱ)and consumed the formed PFRs.Adsorption kinetics and X-ray photoelectron spectroscopy analysis indicated that the FBCs effectively enhanced the Cr(Ⅵ)removal efficiency by 1.54-8.20 fold and the Cr(Ⅵ)reduction efficiency by 1.88-9.29 fold compared to those of BC.PFRs quenching and competitive reductant addition experiments revealed that the higher Cr(Ⅵ)reduction performance of FBCs was mainly attributed to the formed PFRs,which could contribute to~74.0%of Cr(Ⅵ)reduction by direct or indirect electron transfer.The PFRs on FBCs surfaces could promote the Fe(Ⅲ)/Fe(Ⅱ)cycle through single electron transfer and synergistically accelerate~52.3%of Cr(Ⅵ)reduction.This study provides an improved understanding of the reduction mechanism of iron-modified biochar PFRs on Cr(Ⅵ)in environments. | Shujie Hu Chengshuai Liu Hongling Bu Manjia Chen Ying-heng Fei | 2024 | Journal of Environmental Sciences2024，，3： | 1 |
| 18 | Identification of Glutaminyl Cyclase isoenzyme isoQC as a regulator of SIRPα-CD47 axis显示文摘Dear Editor,Cancer cells often upregulate the expression of ligands for the inhibitory immune checkpoints receptor to escape anti-tumor immunity1. Targeting inhibitory immune checkpoints has become one of the most promising anticancer therapeutic inventions. Infiltration of myeloid cells, especially phagocytic cells, to tumors is often associated with chemotherapy resistance and progression of various cancer types. Phagocytosis of cancer cells is the major mechanism for these myeloid cells-mediated antitumor activity. However, many types of cancer cells express high level of ‘don’t eat me’ signals on the cell surface to escape the phagocytic cells-mediated antitumor immunity. | Zhiqiang Wu Linjun Weng Tengbo Zhang Hongling Tian Lan Fang Hongqi Teng Wen Zhang Jing Gao Yun Hao Yaxu Li Hu Zhou Ping Wang | 2019 | Cell Research2019，29，6： | 1 |
| 19 | Modula- tion of protein release from biodegradable core-shell structured fibers prepared by coaxial electraspinning显示文摘 | Jiang Hongling Hu Yingqian Zhao Pengcheng | 2006 | J Biomed Mater Res B: Appl Biomater2006，79，1： | 1 |
| 20 | AlGaN/AlN/GaN/SiC HEMT structure with high mobility GaN thin layer as channel grown by MOCVD显示文摘 | Xiaoliang Wang Guoxin Hu Zhiyong Ma Junxue Ran Cuimei Wang Hongling Xiao Jian Tang Jianping Li Junxi Wang Yiping Zeng Jinmin Li Zhanguo Wang | 2006 | Journal of Crystal Growth2006，，： | 1 |
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