|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Reappraisement and refinement of zircon U-Pb isotope and trace element analyses by LA-ICP-MS显示文摘A protocol was established for simultaneous measurements of zircon U-Pb ages and trace elements by LA-ICP-MS at spot sizes of 16 32 μm.This was accomplished by introducing N 2 into ICP to increase the sensitivity.The obtained U-Pb ages for zircon standards GJ-1,TEMORA and SK10-2 are consistent with the preferred values within about 1% uncertainty (2σ) by simple external calibration against zircon standard 91500.Different data reduction softwares could yield different uncertainties for calculation of U-Pb ages.The commercially available program GLITTER4.4 could apply an improper uncertainty calculation strategy,but it may yield artificial high precisions for single analyses.Our trace element analyses indicate that Si is not an ideal internal standard for zircon when calibrated against the NIST glasses.Calibration against the NIST glasses using Si as an internal standard,a systematic deviation of 10% 30% was found for most trace elements including Zr.However,the trace element compositions of zircon can be accurately measured by calibration against multiple reference materials with natural compositions (e.g.,BCR-2G,BHVO-2G and BIR-1G),or calibration against NIST SRM 610 and using Zr as an internal standard.Analyses of two pieces of GJ-1 demonstrate that it is relatively homogenous for most trace elements (except for Ti). | LIU YongSheng HU ZhaoChu ZONG KeQing GAO ChangGui GAO Shan XU Juan CHEN HaiHong | 2010 | Chinese Science Bulletin2010，55，15： | 1011 |
| 2 | Characteristics of Settings and Etiologic Agents of Foodborne Disease Outbreaks—China,2020显示文摘Introduction:Foodborne diseases are a growing public health problem and have caused a large burden of disease in China.This study analyzed epidemiological characteristics of foodborne diseases in China in 2020 to provide a scientific basis for prevention and control measures.Methods:Data were collected from 30 of 31 provincial-level administrative divisions(PLADs)in the mainland of China,excluding Xizang(Tibet)Autonomous Region,via the National Foodborne Disease Outbreaks Surveillance System・The number and proportion of outbreaks,illnesses,hospitalizations,deaths by setting,pathogen-food category pairs and etiology were calculated.Results:In 2020,7,073 foodborne disease outbreaks were reported,resulting in 37,454 illnesses and 143 deaths.Among the identified pathogens,microbial pathogens were the most common confirmed etiology,accounting for 41.7%of illnesses.Poisonous mushrooms caused the largest proportion of outbreaks(58.0%)and deaths(57.6%).For venues where foodborne disease outbreaks occur,household had the highest number of outbreaks(4,140)and deaths(128),and catering service locations caused the largest proportion of illnesses(59.9%).Outbreaks occurring between June and September accounted for 62.8%of total outbreaks.Conclusions:Foodborne disease outbreaks mainly occurred in households・Microbial pathogens remained the top cause of outbreak-associated illnesses.Poisonous mushrooms were ranked the top cause of deaths in private homes in China.The supervision and management of food safety and health education should be strengthened to reduce the burden of foodborne diseases・Publicity should be increased to reduce the incidence of mushroom poisonings in families,and supervision and management of food should be strengthened to reduce microbial contamination. | Hongqiu Li Weiwei Li Yue Dai Yuyan Jiang Junhua Liang Santao Wang Maoqiang Zhuang Zheng Huang Lizi Xu Bo Xue Jikai Liu Haihong Han Sara M.Pires Ping Fu Yunchang Guo | 2021 | China CDC weekly2021，3，42： | 14 |
| 3 | Hierarchical construction of CNT networks in aramid papers for high-efficiency microwave absorption显示文摘Carbon nanotubes(CNTs)incorporated polymeric composites have been extensively investigated for microwave absorption at target frequencies to meet the requirement of radar cross-section reduction.In this work,a strategy of efficient utilization of CNT in producing CNT incorporated aramid papers is demonstrated.The layer-by-layer self-assembly technique is used to coat the surfaces of meta-aramid fibers and fibrils with CNT,providing novel raw materials available for the large-scale papermaking.The hierarchical construction of CNT networks resolves the dilemma of increasing CNT content and avoiding the agglomeration of CNT,which is a frequent challenge for CNT incorporated polymeric composites.The composite paper,which contains abundant heterogeneous interfaces and long-range conductive networks,is capable of reaching a high permittivity and dielectric loss tangent at a low CNT loading,its complex permittivity is,so far,adjustable in the range of(1.20−j0.05)to(25.17−j18.89)at 10 GHz.Some papers with optimal matching thicknesses achieve a high-efficiency microwave absorption with a reflection loss lower than−10 dB in the entire X-band. | You Wu Li Chen Yixuan Han Panbo Liu Haihong Xu Guanze Yu Yingying Wang Tao Wen Wenbo Ju Junwei Gu | 2023 | Nano Research2023，16，5： | 9 |
| 4 | Efficacy and safety of low-dose interleukin-2 in combination with methotrexate in patients with active rheumatoid arthritis:a randomized,double-blind,placebo-controlled phase 2 trial显示文摘Rheumatoid arthritis(RA)is an aggressive autoimmune arthritis,and current therapies remain unsatisfactory due to low remission rate and substantially adverse effects.Low-dose interleukin-2(Ld-IL2)is potentially a therapeutic approach to further improve the disease.This randomized,double-blind,placebo-controlled trial was undertaken to evaluate the efficacy and safety of Ld-IL2 in patients with active RA.Patients were randomly assigned(1:1)to receive Ld-IL2,defined as a dose of 1 million IU,or placebo in a 12-week trial with a 12-week follow-up.Three cycles of Ld-IL2 or placebo were administered subcutaneously every other day for 2 weeks(a total of 7 doses),followed by a 2-week break.All patients received a stable dose of methotrexate(MTX).The primary outcomes were the proportion of patients achieving the ACR20,DAS28-ESR<2.6,and the change from baseline in CDAI or SDAI at week 24.Secondary endpoints included other clinical responses and safety.The primary outcomes were achieved in the perprotocol population.The improvements from baseline in CDAI and SDAI were significantly greater across time points for the LdIL2+MTX group(n=17)than for the placebo+MTX group(n=23)(P=0.018 and P=0.015,respectively).More patients achieved ACR20 response in the Ld-IL2+MTX group than those in the placebo+MTX group at week 12(70.6%vs 43.5%)and at week 24(76.5%vs 56.5%)(P=0.014).In addition,low Treg and high IL-21 were associated with good responses to Ld-IL2.Ld-IL-2 treatment was well-tolerated in this study.These results suggested that Ld-IL2 was effective and safe in RA.ClinicalTrials.gov number:NCT 02467504. | Xiaoying Zhang Miao Miao Ruijun Zhang Xu Liu Xiaozhen Zhao Miao Shao Tian Liu Yuebo Jin Jiali Chen Huixin Liu Xia Zhang Yun Li Yunshan Zhou Yue Yang Ru Li Haihong Yao Yanying Liu Chun Li Yuhui Li Limin Ren Yin Su Xiaolin Sun Jing He Zhanguo Li | 2022 | Signal Transduction and Targeted Therapy2022，7，4： | 7 |
| 5 | In situ analysis of major and trace elements of anhydrous minerals by LA-ICP-MS without applying an internal standard显示文摘 | Yongsheng Liu Zhaochu Hu Shan Gao Detlef Günther Juan Xu Changgui Gao Haihong Chen | 2008 | Chemical Geology2008，，1： | 3 |
| 6 | Water cycle evolution in the Haihe River Basin in the past 10000 years显示文摘The water shortage problem in the Haihe River Basin is the most severe in China, and has restricted its economic development. Over-extraction of groundwater has been very severe in the past 30 years. To solve this problem, scientific decisions should be made from a historical perspective. It is important to describe water cycle evolution in the Haihe River basin over the past 10000 years. Datasets of paleoclimate, paleogeography, palynoflora, historical record, isotopic abundance ratio and content were collected for research on different time scales. Some interesting conclusions were drawn by a comprehensive analysis method. First, radiation was the intrinsic force driving the evolution of water cycle. Generally, precipitation increased with temperature. Second, precipitation was high during 8 ka-5 ka B.P., the so-called Yangshao warm period of the Middle Holocene, which recharged the major part of the Quaternary groundwater. Third, heavy floods during this period transported sediment to the seaside, forming the Coastal Plain where cities such as Tianjin, Huanghua, Cangzhou are now located. In the last 3000 years, intermittent moderate floods did not have enough energy to transport sediment to the sea. Rivers usually overflowed in the piedmont region of the Taihang Mountains, and sediment deposited there formed the Piedmont Plain, where locate Shijiazhuang, Xingtai, Handan, Baoding and other cities. Precipitation had a high correlation with temperature in Haihe River Basin in the past 10000 years: the high temperature usually coupled with high precipitation. Today precipitation in the Haihe River Basin is relatively low, owing to low temperature. This study reveals the relationship between temperature, precipitation and river networks in the past 10000 years in Haihe River Basin, which has great scientific and practical importance in understanding the current water circulation and water shortage. | LIU JiaHong XU He QIN DaYong WANG Hao WANG JianHua LI HaiHong BAO ShuJun | 2013 | Chinese Science Bulletin2013，58，27： | 3 |
| 7 | Unraveling specific role of carbon matrix over Pd/quasi-Ce-MOF facilitating toluene enhanced degradation显示文摘Metal organic frameworks(MOFs)derivatives represented by quasi-MOFs have excellent physical and chemical properties and can be applied for the catalytic combustion of volatile organic compounds(VOCs).In this work,Pd/quasi-Ce-BTC synthesized by simple one-step Npyrolysis was applied to the oxidation of toluene,showing excellent toluene catalytic activity(T_(90)=175℃,30000 mL/(g·h)).Microscopic analyses indicate the formation and interaction of a carbon matrix composite quasi-MOF structure interface.The results show that the amorphous carbon matrix formed during the partial pyrolysis of Ce-BTC significantly improves the adsorption and activation capacity of toluene in the reaction,and constructs a reductive system to maintain high concentrations of Ce^(3+)and Pd^(0),which can facilitate the activation and utilization of oxygen in reaction.Quasi in-situ XPS proves that carbon matrix is indirectly involved in the activation and storage of oxygen,and Pd^(0)is the crucial active site for the activation of oxygen.Stability and water resistance tests display good stability of Pd/quasi-Ce-BTC.This work provides a potential method for designing quasi-MOF catalysts towards VOCs effective abatement. | Chunjing Su Zhi Li Mengqi Mao Wenhua Ye Jinping Zhong Quanming Ren Hairong Cheng Haomin Huang Mingli Fu Junliang Wu Yun Hu Daiqi Ye Haihong Xu | 2022 | Journal of Rare Earths2022，40，11： | 2 |
| 8 | Insight into Urban Faults by Wavelet Multi-Scale Analysis and Modeling of Gravity Data in Shenzhen,China显示文摘Urban faults in Shenzhen are potential threats to city security and sustainable development. In consideration of the importance of the Shenzhen fault zone, the author provide a detailed interpretation on gravity data model. Bouguer gravity covering the whole Shenzhen City was calculated with a 1-km resolution. Wavelet multi-scale analysis(MSA) was applied to the Bouguer gravity data to obtain the multilayer residual anomalies corresponding to different depths. In addition, 2D gravity models were constructed along three profiles. The Bouguer gravity anomaly shows an NE-striking high-low-high pattern from northwest to southeast, strongly related to the main faults. According to the results of MSA, the correlation between gravity anomaly and faults is particularly significant from 4 to 12 km depth. The residual gravity with small amplitude in each layer indicates weak tectonic activity in the crust. In the upper layers, positive anomalies along most of faults reveal the upwelling of high-density materials during the past tectonic movements. The multilayer residual anomalies also yield important information about the faults, such as the vertical extension and the dip direction. The maximum depth of the faults is about 20 km. In general, NE-striking faults extend deeper than NW-striking faults and have a larger dip angle. | Chuang Xu Haihong Wang Zhicai Luo Hualiang Liu Xiangdong Liu | 2018 | Journal of Earth Science2018，29，6： | 2 |
| 9 | Phosphate limitation increases coenzyme Q10 production in industrial Rhodobacter sphaeroides HY01显示文摘Coenzyme Q10(CoQ10)is an important component of the respiratory chain in humans and some bacteria.As a high-value-added nutraceutical antioxidant,CoQ10 has excellent capacity to prevent cardiovascular disease.The content of CoQ10 in the industrial Rhodobacter sphaeroides HY01 is hundreds of folds higher than normal physiological levels.In this study,we found that overexpression or optimization of the synthetic pathway failed CoQ10 overproduction in the HY01 strain.Moreover,under phosphate-limited conditions(decreased phosphate or in the absence of inorganic phosphate addition),CoQ10 production increased significantly by 12%to220 mg/L,biomass decreased by 12%,and the CoQ10 productivity of unit cells increased by 27%.In subsequent fed-batch fermentation,CoQ10 production reached 272 mg/L in the shake-flask fermentation and 1.95 g/L in a 100-L bioreactor under phosphate limitation.Furthermore,to understand the mechanism associated with CoQ10 overproduction under phosphate-limited conditions,the comparatve transcriptome analysis was performed.These results indicated that phosphate limitation combined with glucose fed-batch fermentation represented an effective strategy for CoQ10 production in the HY01.Phosphate limitation induced a pleiotropic effect on cell metabolism,and that improved CoQ10 biosynthesis efficiency was possibly related to the disturbance of energy metabolism and redox potential. | Lu Zhang Leshi Liu Ke-Feng Wang Lan Xu Liming Zhou Weishan Wang Chuan Li Zheng Xu Tong Shi Haihong Chen Yuanhang Li Hui Xu XiuLiang Yang Zhichun Zhu Biqin Chen Dan Li Guanghuang Zhan Si-Liang Zhang Li-Xin Zhang Gao-Yi Tan | 2019 | Synthetic and Systems Biotechnology2019，4，4： | 2 |
| 10 | Ring-restricted N-nitrosated rhodamine as a green-light triggered,orange-emission calibrated and fast-releasing nitric oxide donor显示文摘Nitric oxide(NO) donors are versatile tools for nitric oxide biology. The biological response of NO is dependent on the transient concentration and the sustained duration. N-Nitrosated rhodamines are photo-triggered and photo-calibrated NO donors. We recently discovered that suppression of the dihedral angle between the N-nitroso fragment with the rhodamine scaffold facilitates NO release.Inspired by this discovery, we developed a fast-releasing NO donor (NOD575) suitable for biological applications, e.g., the pulmonary arterial smooth muscle cells(PASMCs). | Haihong He Tingting He Ziqian Zhang Xiu Xu Huibin Yang Xuhong Qian Youjun Yang | 2018 | Chinese Chemical Letters2018，29，10： | 2 |
| 11 | Dependence of UV-B-induced camptothecin production on nitrate reductase-mediated nitric oxide signaling in Camptotheca acuminata suspension cell cultures显示文摘 | Jiazhao Ruan Jinjie Zhang Mengya Li Yun Zhu Lina Sun Haihong Jin Hu Su Maojun Xu | 2014 | Plant Cell, Tissue and Organ Culture (PCTOC)2014，，2： | 1 |
| 12 | Effects of Zr content on electrochemical performance of Ti/Sn-Ru-Co-ZrO_(x)electrodes显示文摘The low cell voltage during electrolytic Mn from the MnCl_(2) system can effectively reduce the power consumption.In this work,the Ti/Sn−Ru−Co−Zr modified anodes were obtained by using thermal decomposition oxidation.The physical parameters of coatings were observed by SEM(scanning electron microscope).Based on the electrochemical performance and SEM/XRD(X-ray diffraction)of the coatings,the influence of Zr on electrode performance was studied and analyzed.When the mole ratio of Sn−Ru−Co−Zr is 6:1:0.8:0.3,the cracks on the surface of coatings were the smallest,and the compactness was the best due to the excellent filling effect of ZrO_(2)nanoparticles.Moreover,the electrode prepared under this condition had the lowest mass transfer resistance and high chloride evolution activity in the 1mol%NH_(4)Cl and 1.5mol%HCl system.The service life of 3102 h was achieved according to the empirical formula of accelerated-life-test of the new type anode. | Linhui Chang Sheng Chen Xionghui Xie Buming Chen Haihong Qiao Hui Huang Zhongcheng Guo Ruidong Xu | 2022 | International Journal of Minerals,Metallurgy and Materials2022，29，12： | 1 |
| 13 | Dscam mutation leads to hydrocephalus and decreased motor function显示文摘The nervous system is one of the most complicated organ systems in invertebrates and vertebrates.Down syndrome cell adhesion molecule(DSCAM)of the immunoglobulin(Ig)superfamily is expressed widely in the nervous system during embryonic development.Previous studies in Drosophila suggest that Dscam plays important roles in neural development including axon branching,dendritic tiling and cell spacing.However,the function of the mammalian DSCAM gene in the formation of the nervous system remains unclear.Here,we show that Dscam^(del17) mutant mice exhibit severe hydrocephalus,decreased motor function and impaired motor learning ability.Our data indicate that the mammalian DSCAM gene is critical for the formation of the central nervous system. | Yiliang Xu Haihong Ye Yan Shen Qi Xu Li Zhu Jianghong Liu Jane Y.Wu | 2011 | Protein & Cell2011，2，8： | 1 |
| 14 | Expression of human FUS protein in Drosophila leads to progressive neurodegeneration显示文摘Mutations in the Fused in sarcoma/Translated in liposarcoma gene(FUS/TLS,FUS)have been identified among patients with amyotrophic lateral sclerosis(ALS).FUS protein aggregation is a major pathological hallmark of FUS proteinopathy,a group of neurodegenerative diseases characterized by FUS-immunoreactive inclusion bodies.We prepared transgenic Drosophila expressing either the wild type(Wt)or ALS-mutant human FUS protein(hFUS)using the UAS-Gal4 system.When expressing Wt,R524S or P525L mutant FUS in photoreceptors,mushroom bodies(MBs)or motor neurons(MNs),transgenic flies show age-dependent progressive neural damages,including axonal loss in MB neurons,morphological changes and functional impairment in MNs.The transgenic flies expressing the hFUS gene recapitulate key features of FUS proteinopathy,representing the first stable animal model for this group of devastating diseases. | Yanbo Chen Mengxue Yang Jianwen Deng Xiaoping Chen Ye Ye Li Zhu Jianghong Liu Haihong Ye Yan Shen Yan Li Elizabeth J.Rao Kazuo Fushimi Xiaohong Zhou Eileen H.Bigio Marsel Mesulam Qi Xu Jane Y.Wu | 2011 | Protein & Cell2011，2，6： | 1 |
| 15 | Ozone induces flavonol production of Ginkgo biloba cells dependently on nitrate reductase-mediated nitric oxide signaling显示文摘 | Maojun Xu Yun Zhu Jufang Dong Haihong Jin Lina Sun Zhian Wang Zhonghua Lu Ming Zhang Dan Lu | 2011 | Environmental and Experimental Botany2011，，： | 1 |
| 16 | Terahertz Spectroscopy for Accurate Identification of Panax quinquefolium Basing on Nonconjugated 24(R)-Pseudoginsenoside F_(11)显示文摘Panax quinquefolium is a perennial herbaceous plant that contains many beneficial ginsenosides with diverse pharmacological effects.24(R)-pseudoginsenoside F_(11)is specific to P.quinquefolium,a useful biomarker for distinguishing this species from other related plants.However,because of its nonconjugated property and the complexity of existing detection methods,this biomarker cannot be used as the identification standard.We herein present a stable 24(R)-pseudoginsenoside F_(11)fingerprint spectrum in the terahertz band,thereby proving that F_(11)can be detected and quantitatively analyzed via terahertz spectroscopy.We also analyzed the sample by high-performance liquid chromatography-triple quadrupole mass spectrometry.The difference between the normalized data for the two analytical methods was less than 5%.Furthermore,P.quinquefolium from different areas and other substances can be clearly distinguished based on these terahertz spectra with a standard principal component analysis.Our method is a fast,simple,and cost-effective approach for identifying and quantitatively analyzing P.quinquefolium. | Tianyi Kou Ji Ye Jing Wang Yan Peng Zefang Wang Chenjun Shi Xu Wu Xitian Hu Haihong Chen Ling Zhang Xiaohong Chen Yiming Zhu Huiliang Li Songlin Zhuang | 2021 | Plant Phenomics2021，3，1： | 1 |
| 17 | In situ analysis of major andtrace elements of anhydrous minerals by LA-ICP-MS withoutapplying an internal standard 显示文摘 | Liu Yongsheng Hu Zhaochu Gao Shan Günther D Xu Juan Gao Changgui Chen Haihong | 2008 | Chem Geol2008，257，12： | 1 |
| 18 | In situ analysis of major and trace elements of anhydrous minerals by LA-ICP-MS without applying an internal standard 显示文摘 | Liu Yongsheng Hu Zhaochu Gao Shan Gfintherc D Xu Juan Gao Changgui Chen Haihong | 2008 | Chem Geol2008，257，12： | 1 |
| 19 | Quantum dots co-sensitized solar cells: a new assembly process of CdS/CdSe linked to mesoscopic TiO 2 -nano-SiO 2 hybrid film显示文摘 | Renbao Wang Lei Wan Haihong Niu Qiong Ma Shiding Miao Jinzhang Xu | 2013 | Journal of Sol-Gel Science and Technology2013，，3： | 1 |
| 20 | In situ analysis of major and trace elements of anhydrous minerals by LA-ICP-MS without applying an internal standard 显示文摘 | Liu Yongsheng Hu Zhaochu Gac Shan Gtinther D Xu Juan Gan Changgui Chen Haihong | 2008 | Chem Geol2008，257，12： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员