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| 1 | Anti-inflammatory and anti-thrombogenic effects of atorvastatin in acute ischemic stroke显示文摘Atorvastatin decreases inflammation and thrombogenesis in patients with carotid artery plaque. Atorvastatin is administered to lower lipid levels, but its anti-inflammatory and anti-thrombogenic effects remain unclear. Eighty-nine patients from northeastern China with acute ischemic stroke caused by large-artery atherosclerosis were randomly divided into the study and control groups. All patients received routine treatment, including antiplatelet therapy, circulatory support, and symp-tomatic treatment. The study group (n=43) also received daily atorvastatin 20 mg/d, and the control group (n=46) received daily placebo pills containing glucose. After 4 weeks, the levels of C-reactive protein, fibrinogen, and D-dimer were significantly lower in the study group than in the control group. Decreases in the levels of C-reactive protein, fibrinogen, and D-dimer were not associated with de-creases in the levels of triacylglycerol and low-density lipoprotein cholesterol. These results suggest that atorvastatin reduces inflammation and thrombogenesis independent of its lipid-lowering effects in patients with acute ischemic stroke caused by large-artery atherosclerosis. | Lianqiu Min Shuai Shao Xiaoning Wu Lin Cong Ping Liu Haiping Zhao Yumin Luo | 2013 | Neural Regeneration Research2013，8，23： | 19 |
| 2 | Correlation between tongue manifestations and glucose, total cholesterol, and high-density lipoprotein cholesterol in patients with acute cerebral infarction显示文摘OBJECTIVE: To analyze the association between tongue manifestations and the levels of glucose (GLU), total cholesterol(TCH), and high-density lipoprotein cholesterol(HDL-C) in subjects with acute cerebral infarction.METHODS: Hospitalized patients with first unilateral cerebral infarction in the Neurological Department of Xuanwu Hospital were included and the correlation between tongue fur color, fur nature,and the levels of GLU,TCH, HDL-C were analyzed.RESULTS: HDL level in the thin fur group was higher than that in the thick fur group(P=0.02). The difference in the levels of GLU,TCH, and HDL-C among the groups was significant(P<0.05), classified in terms of slippery, moist, and dry fur. Further comparison between the groups by Student-Newman-Keuls test showed that GLU level in the dry fur group was the highest. Moreover, the TCH level in the slippery fur group was higher than the other two groups.CONCLUSION: A correlation between tongue manifestations and GLU, TCH, HDL-C was identified in the patients with acute cerebral infarction. | Ping Liu Li Gao Juexian Song Haiping Zhao XiaoguangWu Liyuan Huang Pingping Wang Yumin Luo | 2014 | Journal of Traditional Chinese Medicine2014，34，2： | 14 |
| 3 | MicroRNAs in tomato plants显示文摘MicroRNAs (miRNAs) are a specialized class of small silencing RNAs that regulate gene expression in eukaryotes.In plants,miRNAs negatively regulate target mRNAs containing a highly complementary sequence by either mRNA cleavage or translational repression.As a model plant to study fleshy fruit ripening,miRNA studies in tomato have made great progress recently.MiRNAs were predicted to be involved in nearly all biological processes in tomato,particularly development,differentiation,and biotic and abiotic stress responses.Surprisingly,several miRNAs were verified to be involved in tomato fruit ripening and senescence.Recent studies suggest that miRNAs are related to host-virus interactions,which raises the possibility that miRNAs can be used as diagnostic markers for response to virus infection in tomato plants.In this review,we summarize our current knowledge systematically and advance future directions for miRNA research in tomato. | ZUO JinHua WANG YunXiang LIU HaiPing MA YuanZheng JU Zheng ZHAI BaiQiang FU DaQi ZHU Yi LUO YunBo ZHU BenZhong | 2011 | Science China(Life Sciences)2011，54，7： | 13 |
| 4 | Virus-induced Gene Silencing in Eggplant(Solanum melongena)显示文摘Eggplant(Solanum melongena)is an economically important vegetable requiring investigation into its various genomic functions.The current limitation in the investigation of genomic function in eggplant is the lack of effective tools available for conducting functional assays.Virus-induced gene silencing(VIGS)has played a critical role in the functional genetic analyses.In this paper,TRV-mediated VIGS was successfully elicited in eggplant.We first cloned the CDS sequence of PDS(PHYTOENE DESATURASE) in eggplant and then silenced the PDS gene.Photo-bleaching was shown on the newly-developed leaves four weeks after agroinoculation,indicating that VIGS can be used to silence genes in eggplant.To further illustrate the reliability of VIGS in eggplant,we selected Chl H,Su and CLA1 as reporters to elicit VIGS using the high-pressure spray method.Suppression of Chl H and Su led to yellow leaves,while the depletion of CLA1 resulted in albino.In conclusion,four genes,PDS,Chl H,Su(Sulfur),CLA1,were down-regulated significantly by VIGS,indicating that the VIGS system can be successfully applied in eggplant and is a reliable tool for the study of gene function. | Haiping Liu Daqi Fu Benzhong Zhu Huaxue Yan Xiaoying Shen Jinhua Zuo Yi Zhu Yunbo Luo | 2012 | Journal of Integrative Plant Biology2012，54，6： | 11 |
| 5 | Publication trends in studies examining radix notoginseng as a treatment for ischemic brain injury显示文摘Acute ischemic stroke has become a major disease burden with high mortality and morbidity rates. There is a lack of evidence-based medicine confirming the efficacy of common treatments. Panax notoginseng saponins, the main active ingredient of radix notoginseng, have a neuroprotective role in ischemic brain injury, and have been popularized as a maintenance treatment for acute cerebral infarction and its sequelae. We conducted literature searches on the Web of Science, ClinicalTrials.gov, Cochrane Collaboration, CNKI, Wanfang and the China Scientific & Technological Achievements Database and analyzed the experimental and clinical outcomes of studies investigating the use of radix notoginseng in the treatment of ischemic brain injury to improve the understanding of relevant research trends and existing problems. We found that over the past 10 years, China has maintained its interest in Panax notoginseng research, while such studies are scarce on the Web of Science. However, Chinese researchers often focus on the neuroprotective role of radix notoginseng in ischemic brain injury, but there are no large-scale clinical data to confirm its efficacy and safety. There remains a need for more rigorous large-sample randomized controlled clinical trials with long-term follow-up, to determine whether radix notoginseng lowers stroke recurrence and improves patient's quality of life. | Haiping Li Luo Qiang Chunyang Zhang Chaohui Wang Zhenxing Mu Ligang Jiang | 2014 | Neural Regeneration Research2014，9，17： | 5 |
| 6 | Selective recovery of Cu^2+ and Ni^2+ from wastewater using bioelectrochemical system显示文摘作为 bioelectrochemical 系统,微生物引起的燃料房间(MFC ) 和微生物引起的电解房间(MEC ) 被开发有选择地恢复 Cu < 啜 class= “ a-plus-plus ” >2+ 和 Ni < 啜 class= “ a-plus-plus ” > 从废水的 2+ 个 离子。废水在系统的阴极房间被对待,在哪个 Cu < 啜 class= “ a-plus-plus ” >2+ 和 Ni < 啜 class= “ a-plus-plus ” >2+ 个 离子被分别地使用 MFC 和 MEC 移开。在起始的 Cu < 啜 class= “ a-plus-plus ” > 500 mg 瀠牥散瑮条 ? 景漠瑵異 ? 慶畬 ? 景椠摮獵牴 ? 湩敶瑳摥戠 ? 的 2+ 集中潈杮? 湯 ?? 捡潡 ? 慔睩湡愠摮愠牢慯? 攠敮杲 ? 牰捩 ? 湡 ? 湩敶瑳敭瑮漠 ? 諗棔娹驺硴超 _ 捥湨汯杯捩污愠瑣癩瑩敩 ? 潦 ? 湩畤瑳祲挠畯摬戠 ? 潰獳扩敬挠湯牴扩瑵牯 ? 湡 ? 牤癩牥 ? 潴琠敨椠摮獵牴慩? 湥牥祧攠晦捩敩据? | Haiping LUO Bangyu QIN Guangli LIU Renduo ZHANG Yabo TANG Yanping HOU | 2015 | Frontiers of Environmental Science & Engineering2015，9，3： | 4 |
| 7 | A pulsed switching peroxi-coagulation process to control hydroxyl radical production and to enhance 2,4-Dichlorophenoxyacetic acid degradation显示文摘The aim of this study was to develop a new pulsed switching peroxi-coagulation system to control hydroxyl radical(∙OH)production and to enhance 2,4-Dichlorophenoxyacetic acid(2,4-D)degradation.The system was constructed with a sacrifice iron anode,a Pt anode,and a gas diffusion cathode.Production of H_(2)O_(2) and Fe^(2+)was controlled separately by time delayers with different pulsed switching frequencies.Under current densities of 5.0 mA/cm^(2)(H_(2)O_(2))and 0.5 mA/cm^(2)(Fe^(2+)),the∙OH production was optimized with the pulsed switching frequency of 1.0 s(H_(2)O_(2)):0.3 s(Fe^(2+))and the ratio of H_(2)O_(2) to Fe^(2+)molar concentrations of 6.6.Under the optimal condition,2,4-D with an initial concentration of 500 mg/L was completely removed in the system within 240 min.The energy consumption for the 2,4-D removal in the system was much lower than that in the electro-Fenton process(686 vs.13610 kWh/kg TOC).The iron consumption in the system was~20 times as low as that in the peroxi-coagulation process(19620 vs.3940400 mg/L)within 240 min.The system should be a promising peroxi-coagulation method for organic pollutants removal in wastewater. | Yaobin Lu Songli He Dantong Wang Siyuan Luo Aiping Liu Haiping Luo Guangli Liu Renduo Zhang | 2018 | Frontiers of Environmental Science & Engineering2018，12，5： | 3 |
| 8 | Synthesis and characterization of stable osmafuran starting from HC≡CCH(OH)C≡CH and OsHCl(CO)(PPh_3)_3显示文摘This paper presents a new convenient route to prepare osmafuran starting from readily accessible HC≡C CH(OH)C≡CH and OsHCl(CO)(PPh3)3.Treatment of a solution of OsHCl(CO)(PPh3)3 in dichloromethane with HC≡C CH(OH)C≡CH,followed by the addition of acetic acid,produced osmafuran [Os(CHC(PPh3)CO(CH2CH3))Cl(CO)(PPh3)2]Cl(2).2 has been isolated in good yield and fully characterized.1H and 13C NMR spectra show the characteristic downfield chemical shifts of the ring hydrogen and carbon atoms.NMR and X-ray diffraction data provide strong evidence for the aromatic nature of 2.Probably due to the effect of the phosphonium substituent,2 exhibits remarkable thermal stability,air stability and lower reactivity. | ZHANG Hong,LIN Ran,LUO Ming & XIA HaiPing State Key Laboratory for Physical Chemistry of Solid Surfaces College of Chemistry and Chemical Engineering,Xiamen University,Xiamen 361005,China | 2010 | Science China Chemistry2010，53，9： | 2 |
| 9 | Compound Gaoziban tablet(复方高滋斑片) alleviates depression via toll-like receptor 4/myeloid differentiation factor 88/nuclear factor-kappa B pathway显示文摘OBJECTIVE: To evaluate the effect of compound Gaoziban tablet(复方高滋斑片, CGZBT) on depression, and to investigate the underlying mechanism. METHODS: The components of CGZBT were analysed by high-performance liquid chromatography. Then, we assessed the effects of varying doses of CGZBT on an established chronic unpredictable mild stress(CUMS) model in rats. Whether animals were depressed was evaluated by sucrose preference test, open field test and forced swimming test. Neurotransmitters of hippocampus were detected by liquid chromatography-mass spectrometry. Serum levels of tumor necrosis factor-alpha(TNF-α), interleukin(IL)-1β, IL-6, IL-4, and IL-10 were measured by enzyme-linked immunosorbent assay. Expressions of toll-like receptor 4(TLR4), myeloid differentiation factor 88(My D88), phospho-nuclear factorkappa B(p-NF-κB), cyclooxygenase-2(COX-2), ionized calcium binding adapter molecule-1(IBA-1) were assessed by immunohistochemical staining and western blotting. RESULTS: Eight compounds were identified from CGZBT, moreover, our results showed that CGZBT effectively reversed the CUMS-induced decrease in sucrose preference, shortened the movement distance and prolonged immobility time. CGZBT significantly increased levels of 5-hydroxytryptamine, dopamine, norepinephrine, 5-hydroxyindoleacetic acid levels, and reduced the expression of TNF-α, IL-1β, IL-6, yet increased IL-4 and IL-10. Furthermore, the expressions of TLR4, My D88, COX-2, p-NF-κB and IBA-1 in hippocampus were effectively reversed after treatment with CGZBT. CONCLUSIONS: These results indicated that CGZBT could, at least in part, alleviate depression induced by CUMS via the TLR4/My D88/NF-κB pathway, suggesting its potential as an antidepressant drug. | ZOU Xinshuang SHI Lei YIN Hailong LI Haiping WANG Mengheng SONG Wanci LUO Laichun WU Hezhen YANG Yanfang ZAN Junfeng LIU Yanwen DAN Hanxiong YIN Qiang YOU Pengtao | 2022 | Journal of Traditional Chinese Medicine2022，42，6： | 2 |
| 10 | Biomarkers of aging显示文摘Aging biomarkers are a combination of biological parameters to(i)assess age-related changes,(ii)track the physiological aging process,and(iii)predict the transition into a pathological status.Although a broad spectrum of aging biomarkers has been developed,their potential uses and limitations remain poorly characterized.An immediate goal of biomarkers is to help us answer the following three fundamental questions in aging research:How old are we?Why do we get old?And how can we age slower?This review aims to address this need.Here,we summarize our current knowledge of biomarkers developed for cellular,organ,and organismal levels of aging,comprising six pillars:physiological characteristics,medical imaging,histological features,cellular alterations,molecular changes,and secretory factors.To fulfill all these requisites,we propose that aging biomarkers should qualify for being specific,systemic,and clinically relevant. | Aging Biomarker Consortium Hainan Bao Jiani Cao Mengting Chen Min Chen Wei Chen Xiao Chen Yanhao Chen Yu Chen Yutian Chen Zhiyang Chen Jagadish K Chhetri Yingjie Ding Junlin Feng Jun Guo Mengmeng Guo Chuting He Yujuan Jia Haiping Jiang Ying Jing Dingfeng Li Jiaming Li Jingyi Li Qinhao Liang Rui Liang Feng Liu Xiaoqian Liu Zuojun Liu Oscar Junhong Luo Jianwei Lv Jingyi Ma Kehang Mao Jiawei Nie Xinhua Qiao Xinpei Sun Xiaoqiang Tang Jianfang Wang Qiaoran Wang Siyuan Wang Xuan Wang Yaning Wang Yuhan Wang Rimo Wu Kai Xia Fu-Hui Xiao Lingyan Xu Yingying Xu Haoteng Yan Liang Yang Ruici Yang Yuanxin Yang Yilin Ying Le Zhang Weiwei Zhang Wenwan Zhang Xing Zhang Zhuo Zhang Min Zhou Rui Zhou Qingchen Zhu Zhengmao Zhu Feng Cao Zhongwei Cao Piu Chan Chang Chen Guobing Chen Hou-Zao Chen Jun Chen Weimin Ci Bi-Sen Ding Qiurong Ding Feng Gao Jing-Dong JHan Kai Huang Zhenyu Ju Qing-Peng Kong Ji Li Jian Li Xin Li Baohua Liu Feng Liu Lin Liu Qiang Liu Qiang Liu Xingguo Liu Yong Liu Xianghang Luo Shuai Ma Xinran Ma Zhiyong Mao Jing Nie Yaojin Peng Jing Qu Jie Ren Ruibao Ren Moshi Song Zhou Songyang Yi Eve Sun Yu Sun Mei Tian Shusen Wang Si Wang Xia Wang Xiaoning Wang Yan-Jiang Wang Yunfang Wang Catherine CL Wong Andy Peng Xiang Yichuan Xiao Zhengwei Xie Daichao Xu Jing Ye Rui Yue Cuntai Zhang Hongbo Zhang Liang Zhang Weiqi Zhang Yong Zhang Yun-Wu Zhang Zhuohua Zhang Tongbiao Zhao Yuzheng Zhao Dahai Zhu Weiguo Zou Gang Pei Guang-Hui Liu | 2023 | Science China(Life Sciences)2023，66，5： | 2 |
| 11 | Phenoldegradation in microbial fuel cells显示文摘 | LUO Haiping LIU Guangli ZHANG Renduo | 2009 | Chemical EngineeringJournal2009，147，2： | 1 |
| 12 | Ionic composition and transport mechanisms in microbial desalination cells显示文摘 | Haiping Luo Pei Xu Peter E. Jenkins Zhiyong Ren | 2012 | Journal of Membrane Science2012，，： | 1 |
| 13 | MicroRNA-124–Mediated Regulation of Inhibitory Member of Apoptosis-Stimulating Protein of p53 Family in Experimental Stroke显示文摘 | Xiangrong Liu Fang Li Shangfeng Zhao Yumin Luo Jun Kang Haiping Zhao Feng Yan Sijie Li Xunming Ji | 2013 | Stroke2013，，7： | 1 |
| 14 | Synthesis, Characterization, and Reactivity of Metalla- Chalcogenirenium Compounds显示文摘Chalcogenirenium cations,featuring an unsaturated three-membered organic ring,are limited but known to be synthesizable from alkynes with bulky electron-donating groups.Metalla-chalcogenirenium compounds have been synthesized as stable compounds through the reactions of a cyclic metal-carbyne complex-metallapentalyne with PhSCI,PhSeCI or PhTeCI.As a result of the high strain in the three-membered metallacycles,the metalla-chalcogenirenium cations react readily with the base or chloride ions.These reactions furnish a series of unprecedented chalcogenirenium cations with intact M=C bonds.The intrinsic stabilization effect of aromaticity is further elucidated by density functional calculations. | Ming Luo Yapeng Cai Xinlei Lin Lipeng Long Hong Zhang Haiping Xia | 2021 | Chinese Journal of Chemistry2021，39，6： | 1 |
| 15 | Hybrid Ant Colony Multi-objective Optimization for Flexible Job Shop Scheduling Problems 显示文摘 | Luo Delin Chen Haiping Wu Shunxiang | 2010 | Journalof Internet Technology2010，11，3： | 1 |
| 16 | Insight into the effect of graphene coating on cycling stability of LiNi_(0.5)Mn_(1.5)O_(4):Integration of structure-stability and surface-stability显示文摘Graphene has presented promising features for application in lithium ion batteries(LIBs)due to its superior electronic conductivity and high surface area.It has been successfully used for modifying cathode materials to meet the increasing demand for LIBs with longer cycle life.However,the improving effect of graphene on cycling stability is still unclear,which restricts its further application in LIBs.Herein,graphene coated hollow sphere-like structure LiNi0.5Mn1.5O4(LNMO)wasdesigned and the improvement mechanism of graphene coating on LNMO’s cycling stability was investigated.The results show that graphene coating not only contributes to suppress structural deformation from mechanistic reaction and extend solid-solution reaction,but also helps protect electrode from corrosion by the products from electrolyte decomposition and suppress the generation of surface defects,especially at high temperature.Owing to graphene coating,graphene coated LNMO can deliver a discharge capacity of 91 mAh g1 with high capacity retention of 82.5%after 1000 cycles under 20C and 83.8 mAh g1 with 94.5%capacity retention after 100 cycles under 2C at 55C.This work deeply explores the effect of graphene coating on cycling stability from crystal stability and surface stability,which will help a wider application of graphene in energy storage field. | Chao Gao Haiping Liu Sifu Bi Shanshan Fan Xiaohuan Meng Qiuying Li Chongxiao Luo | 2020 | Journal of Materiomics2020，6，4： | 1 |
| 17 | Comparison of the removal of monovalent and divalent cations in the microbial desalination cell显示文摘微生物引起的脱盐房间(MDC ) 是一种有希望的技术脱盐水并且同时产生电力。这研究的目的是在 MDC 调查一价、二价的阳离子的脱盐表演,并且讨论离子特征,离子集中,和电的特征的效果。NaCl 的混合的盐答案, MgCl < 潜水艇 class= “ a-plus-plus ” > 2 , KCl,和 CaCl < 潜水艇 class= “ a-plus-plus ” > 有一样的集中的 2 在脱盐房间被使用学习阳离子的移动。结果证明在混合的盐答案,阳离子的电渗析脱盐率是:Ca < 啜 class= “ a-plus-plus ” >2+> Mg < 啜 class= “ a-plus-plus ” >2+> Na < 啜 class= “ a-plus-plus ” >+> K < 啜 class= “ a-plus-plus ” >+ 。更高离子的费用和更小的含水的离子的半径导致了阳离子,离子的费用在比含水的离子的半径更重要的更高的脱盐率。NaCl 和 MgCl 的混合答案 < 潜水艇 class= “ a-plus-plus ” > 有不同集中的 2 在脱盐房间被使用学习离子集中的效果。结果看了那什么时候 Na 的离子集中 < 啜 class= “ a-plus-plus ” >+ 是五分之一个到五次 Mg < 啜 class= “ a-plus-plus ” >2+, 离子集中比电渗析更深刻地影响了分离。与在某个值下面的当前的密度,费用转移效率变得很低,分离是为脱盐负责的主要进程。并且从阳极房间的磷酸盐转移和从阴极房间的钾转移能在 MDC 平衡费用转移的 1%3% 。 | Shanshan CHEN Haiping LUO Yanping HOU Guangli LIU Renduo ZHANG Bangyu QIN | 2015 | Frontiers of Environmental Science & Engineering2015，9，2： | 1 |
| 18 | A novel lactase-catalyzed cathode for microbial fuel ceUs 显示文摘 | Haiping Luo Song Jin Paul H | 2010 | Chemical Engineering Jour- nal2010，165，： | 1 |
| 19 | Pyridine degradation in the microbial fuel cells显示文摘 | Cuiping Zhang Mingchen Li Guangli Liu Haiping Luo Renduo Zhang | 2009 | Journal of Hazardous Materials2009，，1： | 1 |
| 20 | MicroRNA-424 Protects Against Focal Cerebral Ischemia and Reperfusion Injury in Mice by Suppressing Oxidative Stress显示文摘 | Ping Liu Haiping Zhao Rongliang Wang Peng Wang Zhen Tao Li Gao Feng Yan Xiangrong Liu Shun Yu Xunming Ji Yumin Luo | 2015 | Stroke2015，，： | 1 |
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