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| 1 | The angular characteristics of Moon-based Earth observations显示文摘The Moon,Earth’s only natural satellite,is a potential new platform for Earth observation.Moreover,with the wide applicability of the angular information from remote sensing data,it has been attracting increasingly more attention.Accordingly,this study focuses on the angular characteristics of Moon-based Earth observations.Using ephemeris DE430 and Earth orientation parameters,the position and attitude of the Sun,Earth,and Moon were obtained and their coordinates normalized to a single framework using coordinate transformations between the related reference systems.Then,an angular geometric model of Moon-based Earth observations was constructed,and the corresponding angular algorithms were presented.The results revealed the angular range and distribution characteristics of Moon-based Earth observations.For every point on the surface of the Earth,the view and solar zenith angles all vary widely,which decreases with increasing latitude.The view and solar zenith angles all vary widely with the largest range of values in the equatorial and polar regions and a smaller range of values in mid-latitudes.Furthermore,the range of solar angles of Moon-based Earth observations is the same as that of alltime solar angles,indicating the potential for monitoring and understanding large-scale geoscientific phenomena using Moon-based Earth observations. | Huadong Guo Yuanzhen Ren Guang Liu Hanlin Ye | 2020 | International Journal of Digital Earth2020，13，3： | 1 |
| 2 | Temperature and pH effects on biophysical and morphological properties of self-assembling peptide RADA16-I显示文摘 | Ye Zhaoyang Zhang Hangyu Luo Hanlin | 2008 | J Peptide Sci2008，14，2： | 1 |
| 3 | Determination of Enantiomers in ET-26-HCl by Ultra Performance Convergence Chromatography显示文摘[Objectives]To establish an ultra performance convergence chromatography(UPC2)method to determine the content of enantiomers in(R)-2-methoxyethyl1-(1-phenylethyl)-1H-imidazole-5-carboxylate hydrochloride(ET-26 HCl).[Methods]ChiralpakAD-3 chromatographic column(4.6 mm×100 mm,3μm)was used,with 0.1%diethylamine methanol solution-supercritical carbon dioxide(1∶9)as mobile phase;flow rate 2.0 mL/min;back pressure 2000 psi,detection wavelength 240 nm,and column temperature 35℃.[Results]ET-26-HCl was completely separated from the enantiomers,and the linear relationship was good;the detection limit was 1.5μg/mL.[Conclusions]This method is suitable for the determination of the content of enantiomers in ET-26-HCl. | Yaru MA Ting KANG Zhihua CAO Jianrui MU Xianghan YE Hanlin GONG Liying QIU | 2021 | Medicinal Plant2021，12，3： | 0 |
| 4 | Inter-tissue communication of mitochondrial stress and metabolic health显示文摘Mitochondria function as a hub of the cellular metabolic network.Mitochondrial stress is closely associated with aging and a variety of diseases,including neurodegeneration and cancer.Cells autonomously elicit specific stress responses to cope with mitochondrial stress to maintain mitochondrial homeostasis.Interestingly,mitochondrial stress responses may also be induced in a non-autonomous manner in cells or tissues that are not directly experiencing such stress.Such non-autonomous mitochondrial stress responses are mediated by secreted molecules called mitokines.Due to their significant translational potential in improving human metabolic health,there has been a surge in mitokine-focused research.In this review,we summarize the findings regarding inter-tissue communication of mitochondrial stress in animal models.In addition,we discuss the possibility of mitokine-mediated intercellular mitochondrial communication originating from bacterial quorum sensing. | Hanlin Zhang Xinyu Li Wudi Fan Sentibel Pandovski Ye Tian Andrew Dillin | 2023 | Life Metabolism2023，2，1： | 0 |
| 5 | Room-temperature multiple ligands-tailored SnO_(2) quantum dots endow in situ dual-interface binding for upscaling efficient perovskite photovoltaics with high V_(OC)显示文摘The benchmark tin oxide(SnO_(2))electron transporting layers(ETLs)have enabled remarkable progress in planar perovskite solar cell(PSCs).However,the energy loss is still a challenge due to the lack of“hidden interface”control.We report a novel ligand-tailored ultrafine SnO_(2) quantum dots(QDs)via a facile rapid room temperature synthesis.Importantly,the ligand-tailored SnO_(2) QDs ETL with multi-functional terminal groups in situ refines the buried interfaces with both the perovskite and transparent electrode via enhanced interface binding and perovskite passivation.These novel ETLs induce synergistic effects of physical and chemical interfacial modulation and preferred perovskite crystallization-directing,delivering reduced interface defects,suppressed non-radiative recombination and elongated charge carrier lifetime.Power conversion efficiency(PCE)of 23.02%(0.04 cm^(2))and 21.6%(0.98 cm^(2),V_(OC) loss:0.336 V)have been achieved for the blade-coated PSCs(1.54 eV E_(g))with our new ETLs,representing a record for SnO_(2) based blade-coated PSCs.Moreover,a substantially enhanced PCE(V_(OC))from 20.4%(1.15 V)to 22.8%(1.24 V,90 mV higher V_(OC),0.04 cm^(2) device)in the blade-coated 1.61 eV PSCs system,via replacing the benchmark commercial colloidal SnO_(2) with our new ETLs. | Zhiwei Ren Kuan Liu Hanlin Hu Xuyun Guo Yajun Gao Patrick W.K.Fong Qiong Liang Hua Tang Jiaming Huang Hengkai Zhang Minchao Qin Li Cui Hrisheekesh Thachoth Chandran Dong Shen Ming-Fai Lo Annie Ng Charles Surya Minhua Shao Chun-Sing Lee Xinhui Lu Frédéric Laquai Ye Zhu Gang Li | 2021 | Light(Science & Applications)2021，10，12： | 0 |
| 6 | Achieving Tunable Cold/Warm White‑Light Emission in a Single Perovskite Material with Near‑Unity Photoluminescence Quantum Yield显示文摘Single materials that exhibit efficient and stable white-light emission are highly desirable for lighting applications.This paper reports a novel zero-dimensional perovskite,Rb_(4)CdCl_(6):Sn^(2+),Mn^(2+),which demonstrates exceptional white-light properties including adjustable correlated color temperature,high color rendering index of up to 85,and near-unity photoluminescence quantum yield of 99%.Using a co-doping strategy involving Sn^(2+)and Mn^(2+),cyan-orange dual-band emission with complementary spectral ranges is activated by the self-trapped excitons and d-d transitions of the Sn^(2+)and Mn^(2+)centers in the Rb_(4)CdCl_(6)host,respectively.Intriguingly,although Mn^(2+)ions doped in Rb_(4)CdCl_(6)are difficult to excite,efficient Mn^(2+)emission can be realized through an ultra-high-efficient energy transfer between Sn^(2+)and Mn^(2+)via the formation of adjacent exchange-coupled Sn–Mn pairs.Benefiting from this efficient Dexter energy transfer process,the dual emission shares the same optimal excitation wavelengths of the Sn^(2+)centers and suppresses the non-radiative vibration relaxation significantly.Moreover,the relative intensities of the dual-emission components can be modulated flexibly by adjusting the fraction of the Sn^(2+)ions to the Sn–Mn pairs.This co-doping approach involving short-range energy transfer represents a promising avenue for achieving high-quality white light within a single material. | Bo Zhou Aixuan Du Dong Ding Zexiang Liu Ye Wang Haizhe Zhong Henan Li Hanlin Hu Yumeng Shi | 2023 | Nano-Micro Letters2023，15，11： | 0 |
| 7 | Error analysis of exterior orientation elements on geolocation for a Moon-based Earth observation optical sensor显示文摘The Moon is a potential new platform for Earth observation.The advantages of its large-scale observational scope,long temporal duration,and multi-layer detecting of the Earth will undoubtedly advance our understanding of the Earth system.To carry out the observations from a Moon-based optical sensor,the geolocation error caused by exterior orientation elements need to be investigated.This paper analyses the error effects of exterior orientation elements on geolocation for an optical sensor.To estimate the error,we present a geometric image model and utilise some parameters to measure the image offsets.Through a large number of numerical simulations,the results demonstrate that the image offsets are not obvious influenced by the distance and observation angle at mid-high latitude of the Moon and have linear correlation with the increasing errors of the exterior orientation elements.Further,the relationship between the spatial resolution and errors of exterior orientation elements are revealed.Finally,the error characteristics for Moon-based Earth observation are discussed.It is expected that the conclusion drawn in this paper could support the study of a Moon-based Earth observation optical sensor. | Huadong Guo Hanlin Ye Guang Liu Changyong Dou Jing Huang | 2020 | International Journal of Digital Earth2020，13，3： | 0 |
| 8 | Micro pore and throat characteristics and origin of tight sandstone reservoirs: A case study of the Triassic Chang 6 and Chang 8 members in Longdong area, Ordos Basin, NW China显示文摘The microstructure differences of the Triassic Chang 6 and Chang 8 members tight reservoirs in the Longdong area of Ordos Basin were compared by means of cast thin sections, scanning electron microscope, X-ray diffraction, and constant rate mercury injection. Their pore evolution models were established, and the effects of main diagenesis on densification were examined. The throat is the main factor controlling the physical properties of the Chang 6 and Chang 8 members reservoirs: The lower the permeability, the smaller and the more concentrated the throat radius and the larger the proportion of the throats in the effective storage space. There are several obvious differences between Chang 6 and Chang 8 members:(1) with the increase of permeability, the contribution of the relative large throats to the permeability in the Chang 8 member reservoir is more than that in the Chang 6 member reservoir;(2) the control effect on pore-throat ratio of the nano-throats in the Chang 6 member reservoir is more significant. The sedimentary action determines the primary pore structure of the Chang 6 and Chang 8 members sand bodies, and the diagenesis is the main factor controlling the densification of the reservoirs. Because of the difference in rock fabrics and the chlorite content of Chang 6 and Chang 8, the strong compaction resulted in less porosity reduction(17%) of the Chang 81 reservoir with larger buried depth and larger ground temperature than the Chang 63 reservoir(19%). The siliceous, calcareous and clay minerals cement filling the pores and blocking the pore throat, which is the key factor causing the big differences between the reservoir permeability of Chang 6 and Chang 8 members. | LIU Hanlin YANG Youyun WANG Fengqin DENG Xiuqin LIU Ye NAN Junxiang WANG Jin ZHANG Hongjie | 2018 | Petroleum Exploration and Development2018，45，2： | 0 |
| 9 | Clinical utilization of olaparib,a PARP inhibitor,in BRCA1-mutant metastatic acral melanoma显示文摘Acral melanoma(AM)is a rare subtype of cutaneous melanoma linked to poor prognosis,largely due to a lacking of effective targeted therapeutic strategies.Whole-genome sequencing(WGS)data revealed that AM showed a different mutation landscape from cutaneous melanoma.1 BRCA1 and BRCA2 mutations appear in about 3%–16%of AMs.2,3 Pharmacologic inhibition of the DNA repair enzyme PARP has been approved by the FDA as monotherapy in patients with deleterious germline BRCA1/2 mutated advanced ovarian cancer,and the usage has been expanded to metastatic breast cancer,pancreatic cancer,and prostate cancer with homologous recombination repair(HRR)gene defects.4 However,whether AM with BRCA mutations is also sensitive to PARP inhibition is unknown.We identified a stageⅣAM patient with a germline BRCA1 frameshift mutation(BRAC1 G1384Nfs∗7)who was resistant to anti-PD1 therapy.Both patient-derived xenograft and cells(PDX/PDC)models from the same AM patient were established.PARP inhibitor olaparib significantly decreased cell proliferation and slowed tumor growth by increasing DNA double-strand breakage in AM cancer cells.Administration of olaparib to the patient achieved stable disease for 3 months.This study provides preclinical and clinical evidence that PARP inhibitors can slow tumor growth in BRCA1-mutant advanced acral melanoma. | Ruixin Jiang Xianbin Liang Ye Tao Ronghui Xia Ming Lei Bin Jiang Robert LJudson-Torres Yanjie Zhang Weizhen Zhang Hanlin Zeng | 2023 | Genes & Diseases2023，10，5： | 0 |
| 10 | Effects of Zr substitution on soot combustion over cubic fluorite-structured nanoceria:Soot-ceria contact and interfacial oxygen evolution显示文摘Ceria is widely used as a catalyst for soot combustion,but effects of Zr substitution on the reaction mechanism is ambiguous.The present work elucidates effects of Zr substitution on soot combustion over cubic fluorite-structured nanoceria.The nanostructured CeO_(2),Ce_(0.92)Zr_(0.08)O_(2),and Ce_(0.84)Zr_(0.16)O_(2)composed of 5-6 nm crystallites display T_(m-CO2)(the temperature at maximum CO_2 yield)at 383,355,and 375℃under 10 vol.%O_(2)/N_(2),respectively.The size of agglomerate decreases from 165.5 to 51.9-57.3 nm,which is beneficial for the sootceria contact.Moreover,Zr increases the amount of surface oxygen vacancies,generating more active oxygen(O_(2)^-and O^(-))for soot oxidation.Thus,the activities of Ce_(0.92)Zr_(0.08)O_(2)and Ce_(0.84)Zr_(0.16)O_(2)in soot combustion are better than that of CeO_(2).Although oxygen vacancies promote the migration of lattice O~(2-),the enriched surface Zr also inhibits the mobility of lattice O^(2-).Therefore,the T_(m-CO2)of Ce_(0.84)Zr_(0.1)6 O_(2)is higher than that of Ce_(0.92)Zr_(0.08)O_(2).Based on reaction kinetic study,soot in direct contact with ceria preferentially decomposes with low activation energy,while the oxidation of isolated soot occurs through diffusion with high activation energy.The obtained findings provide new understanding on the soot combustion over nanoceria. | Peng Liu Xiaoliang Liang Yanliu Dang Junkai He Alireza Shirazi-Amin Laura A.Achola Shanka Dissanayake Hanlin Chen Mingli Fu Daiqi Ye Steven L.Suib | 2021 | Journal of Environmental Sciences2021，33，3： | 0 |
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