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| 1 | Nanoparticle-immersed paper imprinting mass spectrometry imaging reveals uptake and translocation mechanism of pesticides in plants显示文摘Design and discovery of carrier-mediated modified pesticides are vital for reducing pesticide dosage and increasing utilization,yet it remains a great challenge due to limited insights into plant translocation mechanisms.Nanostructure/nanoparticle assisted laser desorption/ionization strategy has established itself as a preferential analytical tool for biological tissue analysis,whereas potential applications in plant sciences are hindered with regard to the inability to slice plant leaves and petals.Herein,we report gold nanoparticle(AuNP)-immersed paper imprinting mass spectrometry imaging(MSI)for the spatiotemporal visualization of pesticide translocation in plant leaves.This approach plays a dual role in preserving spatial information and improving ionization efficiency for pesticides regardless of imaging artifacts due to homogenous AuNP deposition.Using this MSI platform,we proposed the elaborate plant translocation mechanism of agrochemicals for the first time,which is currently poorly understood.The dynamic processes of carrier-mediated pesticides can be clearly visualized,including crossing of plasma membranes by transporters,translocation downward in stems through the phloem,diffusion to the xylem and,conversely,accumulation at margins of the treated leaves.Moreover,this AuNP-assisted paper imprinting method could be highly compatible with laser-based MSI instruments,expediting researches across a broad range of fields,especially in nanomaterial development and life sciences. | Xinzhou Wu Run Qin Hanxiang Wu Guangkai Yao Yue Zhang Ping Li Yizhu Xu Zhixiang Zhang Zhibin Yin Hanhong Xu | 2020 | Nano Research2020，13，3： | 8 |
| 2 | Analysis of 100 consecutive cases of resectable pancreatic neuroendocrine neoplasms: clinicopathological characteristics and long-term outcomes显示文摘 | Yugang Cheng Hanxiang Zhan Lei Wang Jianwei Xu Guangyong Zhang Zongli Zhang Sanyuan Hu | 2016 | Frontiers of Medicine2016，10，4： | 5 |
| 3 | Self-Powered Intelligent Human-Machine Interaction for Handwriting Recognition显示文摘Handwritten signatures widely exist in our daily lives.The main challenge of signal recognition on handwriting is in the development of approaches to obtain information effectively.External mechanical signals can be easily detected by triboelectric nanogenerators which can provide immediate opportunities for building new types of active sensors capable of recording handwritten signals.In this work,we report an intelligent human-machine interaction interface based on a triboelectric nanogenerator.Using the horizontal-vertical symmetrical electrode array,the handwritten triboelectric signal can be recorded without external energy supply.Combined with supervised machine learning methods,it can successfully recognize handwritten English letters,Chinese characters,and Arabic numerals.The principal component analysis algorithm preprocesses the triboelectric signal data to reduce the complexity of the neural network in the machine learning process.Further,it can realize the anticounterfeiting recognition of writing habits by controlling the samples input to the neural network.The results show that the intelligent human-computer interaction interface has broad application prospects in signature security and humancomputer interaction. | Hang Guo Ji Wan Haobin Wang Hanxiang Wu Chen Xu Liming Miao Mengdi Han Haixia Zhang | 2021 | Research2021，，1： | 4 |
| 4 | Scalable and facile synthesis of V_(2)O_(5) nanoparticles via ball milling for improved aerobic oxidative desulfurization显示文摘In recent years, transition-metal oxides(TMOs) have been long employed for aerobic oxidative desulfurization. However, the inherent bottlenecks, such as the low explosion of active sites, limit the application of bulk TMOs catalyst. In this study, V_(2)O_(5) nanoparticles with oxygen vacancies were prepared in large-scale via facile ball milling strategy with adding oxalic acid as a reducing agent. The as-prepared catalysts exhibit remarkable sulfur removal for oils with different initial S-concentrations and different substrates. Sulfur removal could reach up to 99.7%(< 2 ppm) under the optimized reaction conditions. This work provides a feasible desulfurization strategy for fuel oils. | Yiru Zou Chao Wang Hanxiang Chen Haiyan Ji Qian Zhu Wenshu Yang Linlin Chen Zhigang Chen Wenshuai Zhu | 2021 | Green Energy & Environment2021，6，2： | 4 |
| 5 | Shallow Genetic Structure of Pholis fangi in Bohai Sea and Yellow Sea Inferred from mt DNA Control Region显示文摘Pholis fangi is an ecologically important fish species inhabiting Chinese coastal waters of Yellow Sea and Bohai Sea. To investigate the genetic diversity and population genetic structure of P. fangi, a fragment of 487 bp in the first hypervariable region (HVR-1) of the mitochondrial DNA (mtDNA) control region was sequenced for 181 individuals collected from Bohai Sea and Yel- low Sea. A total of 18 polymorphic sites were detected, which defined 25 haplotypes. A moderate level of haplotype diversity (h = 0.7052) and a low level of nucleotide diversity (π= 0.0028) were detected. Both the phylogenetic tree and the haplotype network showed no significant genealogical structure difference among sampling locations. Pairwise FST comparison and hierarchical mo- lecular variance analysis (AMOVA) revealed that no significant genetic structure difference existed throughout the investigated re- gions, suggesting a high gene exchange among different populations. The results of neutrality test and mismatch distribution analysis indicated that a late Pleistocene population expansion (38000 127000 years ago) happened. Seasonal schooling migration may con- tribute to the genetically homogeneous population structure of the species. | GAO Tianxiang LI Lin FANG Rundong LIU Guanghui WANG Lei XU Hanxiang SONG Na | 2019 | Journal of Ocean University of China2019，18，4： | 2 |
| 6 | Current management of chemotherapy-induced neutropenia in adults:key points and new challenges显示文摘Chemotherapy-induced neutropenia(CIN)is a potentially fatal and common complication in myelosuppressive chemotherapy.The timing and grade of CIN may play prognostic and predictive roles in cancer therapy.CIN is associated with older age,poor functional and nutritional status,the presence of significant comorbidities,the type of cancer,previous chemotherapy cycles,the stage of the disease,specific chemotherapy regimens,and combined therapies.There are many key points and new challenges in the management of CIN in adults including:(1)Genetic risk factors to evaluate the patient’s risk for CIN remain unclear.However,these risk factors urgently need to be identified.(2)Febrile neutropenia(FN)remains one of the most common reasons for oncological emergency.No consensus nomogram for FN risk assessment has been established.(3)Different assessment tools[e.g.,Multinational Association for Supportive Care in Cancer(MASCC),the Clinical Index of Stable Febrile Neutropenia(CISNE)score model,and other tools]have been suggested to help stratify the risk of complications in patients with FN.However,current tools have limitations.The CISNE score model is useful to support decision-making,especially for patients with stable FN.(4)There are still some challenges,including the benefits of granulocyte colony stimulating factor treatment and the optimal antibiotic regimen in emergency management of FN.In view of the current reports,our group discusses the key points,new challenges,and management of CIN. | Committee of Neoplastic Supportive-Care(CONS),China Anti-Cancer Association Committee of Clinical Chemotherapy,China Anti-Cancer Association Yi Ba Yuankai Shi Wenqi Jiang Jifeng Feng Ying Cheng Li Xiao Qingyuan Zhang Wensheng Qiu Binghe Xu Ruihua Xu Bo Shen Zhiguo Luo Xiaodong Xie Jianhua Chang Mengzhao Wang Yufu Li Yuerong Shuang Zuoxing Niu Bo Liu Jun Zhang Li Zhang Herui Yao Conghua Xie Huiqiang Huang Wangjun Liao Gongyan Chen Xiaotian Zhang Hanxiang An Yanhong Deng Ping Gong Jianping Xiong Qinghua Yao Xin An Cheng Chen Yanxia Shi Jialei Wang Xiaohua Wang Zhiqiang Wang Puyuan Xing Sheng Yang Chenfei Zhou | 2020 | Cancer Biology & Medicine2020，17，4： | 2 |
| 7 | Construction of a few-layer g-C_3N_4/α-MoO_3 nanoneedles all-solid-state Z-scheme photocatalytic system for photocatalytic degradation显示文摘The suppression of the recombination of electrons and holes(e–h) and the enhancement of the light absorption of semiconductors are two key points toward efficient photocatalytic degradation.Here,we report a few-layer g-C_3N_4/α-MoO_3 nanoneedles(flg-C_3N_4/α-MoO_3 NNs) all-solid-state Z-scheme mechanism photocatalyst synthesized via a typical hydrothermal method in a controlled manner.The recombination of the photo-induced e–h pairs could be effectively restrained by the Z-scheme passageway between the flg-C_3N_4 and α-MoO_3 NNs in the composite,which could also promise a high redox ability to degrade pollutants.And it became possible for the prepared photocatalyst to absorb light in a wide range of wavelengths.The detailed mechanism was studied by electron spin-resonance spectroscopy(ESR).The low-dimensional nanostructure of the two constituents(α-MoO_3 NNs with one-dimensional structure and flg-C_3N_4 with two-dimensional structure) endowed the composite with varieties of excellent physicochemical properties,which facilitated the transfer and diffusion of the photoelectrons and increased the specific surface area and the active sites.The 10 wt% flg-C_3N_4/α-MoO_3 NNs showed the best photocatalytic performance toward RhB degradation,the rate of which was 71.86%,~2.6 times higher than that ofα-MoO_3 NNs. | Xiaoni Zhang Jianjian Yi Hanxiang Chen Mao Mao Liang Liu Xiaojie She Haiyan Ji Xiangyang Wu Shouqi Yuan Hui Xu Huaming Li | 2019 | Journal of Energy Chemistry2019，28，2： | 2 |
| 8 | Special report on relationship between wind farms and power grids显示文摘The installed capacity of a large scale wind power plant will be up to a number of hundreds MW, and the wind power is transmitted to load centers through long distance transmission lines with 220 kV, 500 kV, or 750 kV. Therefore, it is necessary not only considering the power transmission line between a wind power plant and the first connection node of the power network, but also the power network among the group of those wind power plants in a wind power base, the integration network from the base to the existed grids, as well as the distribution and consumption of the wind power generation by loads. Meanwhile, the impact of wind power stochastic fluctuation on power systems must be studied. In recent years, wind power prediction technology has been studied by the utilities and wind power plants. As a matter of fact, some European countries have used this prediction technology as a tool in national power dispatch centers and wind power companies. | Dai Huizhu Wang Weisheng Li Hanxiang | 2009 | Engineering Sciences2009，7，2： | 1 |
| 9 | Identification of PeniciUium marneffei in Paraffin-Embedded Tissue Using Nested PCR显示文摘 | Hanxiang Zeng Xiqing Li Xiejie Chen | 2009 | 2009，，： | 1 |
| 10 | Sedation depends on the level of sensor block Induced by intrathecal bupivacaine in rats显示文摘 | Hanxiang Ma Katsushi Doi Tetsuro Nikai | 2007 | ASA2007，146，： | 1 |
| 11 | Robust clustering in high dimensional data using statistical depths显示文摘 | DING Yuanyuan DANG Xin PENG Hanxiang | | 0，，7： | 1 |
| 12 | Persistent airwayinflammation and bronchial hyperresponsiveness in patient swith totally controlled asthma 显示文摘 | HanXiang N Jiong Y Yanwai C YW | 2008 | Int J Clin Pract2008，62，4： | 1 |
| 13 | Persistent airway inflammation and bronchial hyper-responsiveness in patients with totally controlled asthma 显示文摘 | Hanxiang N Jiong Y Yanwei C | 2007 | Int J Clin Pract2007，30，： | 1 |
| 14 | Outlier detection with the kernelized spatial depth function显示文摘 | Chen Yixin Dang Xin Peng Hanxiang | 2009 | IEEE Transactions on Pattern Analysis and Machine Intelligence2009，31，2： | 1 |
| 15 | Adult-onset Still's Diseas misdiagnosed as pneumonia:two case reports 显示文摘 | Hanxiang N Xuhong D Huang Y | 2011 | Acta Reumatol Port2011，36，4： | 1 |
| 16 | Outlier Detection with the Kernelized Spatial Depth Function显示文摘 | Chen Yixin Dang Xin Peng Hanxiang | 2009 | Pattern Analysis'' and Machine Intelligence2009，31，2： | 1 |
| 17 | Outlier detection with the Kemelized spatial depth function 显示文摘 | CHEN YIXIN DANG XIN PENG HANXIANG | 2009 | IEEE Transactions on Pattern Analysis and Machine Intelligence2009，31，11： | 1 |
| 18 | Number, distribution, and predicted needed number of general practitioners in China显示文摘Family Medicine and Community Health 2018;6(3):154–159154 www.fmch-journal.org DOI 10.15212/FMCH.2018.0120.2018 Family Medicine and Community Health.Creative Commons Attribution-NonCommercial 4.0 International License CHINA FOCUS CHINA FOCUS Number,distribution,and predicted needed number of general practitioners in China*Baoling Wu1,Hanxiang Gong1,Zhenni Luo1 Abstract Objective:We aimed to investigate the number and distribution of general practitioners(GPs)in China,and to predict the number of GPs needed in the future.Methods:From China Health Statistics Yearbook 2014,China Health Statistics Yearbook 2016 and China Statistical Yearbook 2016,we obtained the number of GPs and the populations in China and each of its regions from 2012 to 2015.IBM SPSS Statistics version 22.0 was used to conduct descriptive statistical analysis.Grey model GM(1,1)and the manpower-to-population ratio method were used to predict the number of GPs needed in China from 2016 to 2020.Results:The total number of GPs in China was 109,794 in 2012,145,511 in 2013,172,597 in 2014,and 188,649 in 2015.The number increased by 78,855 from 2012 to 2015,and the average annual growth rate was 19.77%.By the end of 2015,of the GPs in all of China and in eastern,central,and western China,those who had achieved a GP qualification certificate following training accounted for 63.76%(120,285/188,649),60.06%(62,474/104,015),65.20%(29,565/45,344),and 71.89%(28,246/39,290),respectively,of the total.The number of GPs per 10,000 population in all of China and in eastern,central,and western China was 1.37,1.83,1.05,and 1.06,respectively,and the number of GPs needed for all of China and the eastern,central,and western parts would be 86,275,9787,40,764,and 34,976,respectively,calculated on the basis of the standard of two GPs per 10,000 population.Grey model GM(1,1)predicted that,in accordance with the natural growth trend of GPs,the number of GPs in China would be 220,314 in 2016,253,728 in 2017,293,101 in 2018,339,928 in 2019,and 396,228 in 2020.Moreover,the number of GPs in China in 2020 would be 277,000–415,500 if the calculated number of GPs to the population ratio is based on the standard of two to three GPs per 10,000 population.Conclusion:In recent years,although the number of GPs has increased rapidly,GPs are still greatly needed in all of China and in eastern,central,and western China.Moreover,the distribution of GPs is not balanced,and the number of qualified GPs is far from enough.Therefore,team building for GPs should be strengthened,and the training system for GPs should be improved. | Baoling Wu Hanxiang Gong Zhenni Luo | 2018 | Family Medicine and Community Health2018，6，3： | 1 |
| 19 | A quick emer- gency response model for micro-blog public opinion crisis based on text sentiment intensity 显示文摘 | Xin Mingjun Wu Hanxiang Niu Zhihua | 2012 | Journal of Software2012，7，6： | 1 |
| 20 | Sedation depends on the level of sensor block induced by intrathecal bupivacaine in rats显示文摘 | HANXIANG M A DOI K NIKAI T | 2007 | ASA2007，146，： | 1 |
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