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| 1 | Chinese expert consensus on conversion therapy for hepatocellular carcinoma(2021 edition)显示文摘Recent advances in systemic and locoregional treatments for patients with unresectable or advanced hepatocellular carcinoma(HCC)have resulted in improved response rates.This has provided an opportunity for selected patients with initially unresectable HCC to achieve adequate tumor downstaging to undergo surgical resection,a‘conversion therapy’strategy.However,conversion therapy is a new approach to the treatment of HCC and its practice and treatment protocols are still being developed.Review the evidence for conversion therapy in HCC and develop consensus statements to guide clinical practice.Evidence review:Many research centers in China have accumulated significant experience implementing HCC conversion therapy.Preliminary findings and data have shown that conversion therapy represents an important strategy to maximize the survival of selected patients with intermediate stage to advanced HCC;however,there are still many urgent clinical and scientific challenges for this therapeutic strategy and its related fields.In order to summarize and learn from past experience and review current challenges,the Chinese Expert Consensus on Conversion Therapy for Hepatocellular Carcinoma(2021 Edition)was developed based on a review of preliminary experience and clinical data from Chinese and non-Chinese studies in this field and combined with recommendations for clinical practice.Sixteen consensus statements on the implementation of conversion therapy for HCC were developed.The statements generated in this review are based on a review of clinical evidence and real clinical experience and will help guide future progress in conversion therapy for patients with HCC. | Hui-Chuan Sun Jian Zhou Zheng Wang Xiufeng Liu Qing Xie Weidong Jia Ming Zhao Xinyu Bi Gong Li Xueli Bai Yuan Ji Li Xu Xiao-Dong Zhu Dousheng Bai Yajin Chen Yongjun Chen Chaoliu Dai Rongping Guo Wenzhi Guo Chunyi Hao Tao Huang Zhiyong Huang Deyu Li Gang Li Tao Li Xiangcheng Li Guangming Li Xiao Liang Jingfeng Liu Fubao Liu Shichun Lu Zheng Lu Weifu Lv Yilei Mao Guoliang Shao Yinghong Shi Tianqiang Song Guang Tan Yunqiang Tang Kaishan Tao Chidan Wan Guangyi Wang Lu Wang Shunxiang Wang Tianfu Wen Baocai Xing Bangde Xiang Sheng Yan Dinghua Yang Guowen Yin Tao Yin Zhenyu Yin Zhengping Yu Bixiang Zhang Jialin Zhang Shuijun Zhang Ti Zhang Yamin Zhang Yubao Zhang Aibin Zhang Haitao Zhao Ledu Zhou Wu Zhang Zhenyu Zhu Shukui Qin Feng Shen Xiujun Cai Gaojun Teng Jianqiang Cai Minshan Chen Qiang Li Lianxin Liu Weilin Wang Tingbo Liang Jiahong Dong Xiaoping Chen Xuehao Wang Shusen Zheng Jia Fan 无 | 2022 | Hepatobiliary Surgery and Nutrition2022,11,2: | 4 |
| 2 | Nonreciprocal coherent coupling of nanomagnets by exchange spin waves显示文摘Nanomagnets are widely used to store information in non-volatile spintronic devices.Spin waves can transfer information with low-power consumption as their propagations are independent of charge transport.However,to dynamically couple two distant nanomagnets via spin waves remains a major challenge for magnonics.Here we experimentally demonstrate coherent coupling of two distant Co nanowires by fast propagating spin waves in an yttrium iron garnet thin film with sub-50 nm wavelengths.Magnons in two nanomagnets are unidirectionally phase-locked with phase shifts controlled by magnon spin torque and spin-wave propagation.The coupled system is finally formulated by an analytical theory in terms of an effective non-Hermitian Hamiltonian.Our results are attractive for analog neuromorphic computing that requires unidirectional information transmission. | Hanchen Wang Jilei Chen Tao Yu Chuanpu Liu Chenyang Guo Song Liu Ka Shen Hao Jia Tao Liu Jianyu Zhang Marco A.Cabero Z Qiuming Song Sa Tu Mingzhong Wu Xiufeng Han Ke Xia Dapeng Yu Gerrit E.W.Bauer Haiming Yu | 2021 | Nano Research2021,14,7: | 1 |
| 3 | Interfacial synthesis of polyaniline nanostructures induced by 5-Sulfosalicylic acid显示文摘 | Xuezhi Wang Xiufeng Wang Yuanting Wu Liu Bao Hao Wang | 2010 | Materials Letters2010,,17: | 1 |
| 4 | Fabrication of Polyacrylonitrile/polypyrrole (PAN/PPy) composite nanofibres and nanospheres with core-shell structures by electrospinning 显示文摘 | Li Xianfeng Hao Xiufeng Yu Hubei | 2008 | Materials Letters2008,62,89: | 1 |
| 5 | Preparation of nanosilver panicles into sulfonated poly (ether ether ketone) (S-PEEK)nanostructures by electrospinning显示文摘 | Xianfeng Li Xiufeng Hao Hui Na | 2007 | Materials Letters2007,61,2: | 1 |
| 6 | 1.7 kV normally-off p-GaN gate high-electron-mobility transistors on a semi-insulating SiC substrate显示文摘A study of 1.7 kV normally-off p-GaN gate high-electron-mobility transistors(HEMTs)on SiC substrates is presented.The fabricated p-GaN HEMT with a gate-drain spacing LGD=5μm exhibited a threshold voltage of 1.10 V,a maximum drain current of 235 mA/mm,an ON/OFF ratio of 10^(8),and a breakdown voltage of 440 V.Benefiting from the semi-insulating and high-critical-electric-field substrate,the p-GaN HEMT with LGD=23μm achieved the remarkably high breakdown voltage of 1740 V with substrate grounded.This breakdown voltage is very high compared with the reported values for p-GaN HEMTs on silicon substrates with substrate grounded.The vertical breakdown voltage for the p-GaN-on-SiC material exceeded 3 kV with substrate grounded.In addition,the maximum drain current at 500 K was 48%of that at 300 K with a negligible threshold voltage shift.These results indicate the substantial potential of p-GaN gate HEMTs on SiC substrates for high-voltage power applications. | Shenglei ZHAO Jincheng ZHANG Yachao ZHANG Lansheng FENG Shuang LIU Xiufeng SONG Yixin YAO Jun LUO Zhihong LIU Shengrui XU Yue HAO | 2023 | Science China(Information Sciences)2023,66,2: | 1 |
| 7 | A clinical investigation of the relationship between different sedation depths and the restlessness after using midazolam as an adjuvant during regional anesthesia显示文摘Objective: To investigate the relationship between different sedation depth and the restlessness after using midazolam as an adjuvant during regional anesthesia. Methods: One hundred and fifty patients undergoing regional anesthesia were randomly divided into three groups. In group A, the patients were sedated at the level of OAA/S Ⅳ with midazolam during regional anesthesia. In group B and C, the sedation depths were kept at the levels of Ⅲ and Ⅱ respectively. The changes of BP, HR and SpO2 were recorded before and after midazolam. The rate of restlessness was also evaluated. Results: Blood pressures decreased in certain degree at 5 and 10 min after midazolam compared with those before in all three groups. BP decreased over 20% of the baseline in 4 cases in group A, in 5 cases in group B, and in 5 cases in group C. There was no significant difference in BP dropping among three groups. Compared with group B and C SpO2 dropped significantly at 3 and 5 min after midazolam in group C, in which SpO2 was less than 93% in 8 cases. The restlessness rate in group C was 22%, which was significantly higher than those in group A (2%,P < 0.01) and group B(4%,P < 0.05). Conclusion: The sedation depth is related to the rate of restlessness when midazolam is used as an adjuvant during regional anesthesia. It is suggested that the appropriate sedation depth for the patients under regional anesthesia is OAA/S Ⅲ. | Cunming Liu Guolou Zhang Mei Gao Zhongyun Wang Qianqing Wang Chuanbao Han Xiufeng Hao | 2006 | Journal of Nanjing Medical University2006,20,5: | 0 |
| 8 | Field-free approaches for deterministic spin–orbit torque switching of the perpendicular magnet显示文摘All-electrical driven magnetization switching attracts much attention in next-generation spintronic memory and logic devices,particularly in magnetic random-access memory(MRAM)based on the spin–orbit torque(SOT),i.e.SOT-MRAM,due to its advantages of low power consumption,fast write/read speed,and improved endurance,etc.For conventional SOT-driven switching of the magnet with perpendicular magnetic anisotropy,an external assisted magnetic field is necessary to break the inversion symmetry of the magnet,which not only induces the additional power consumption but also makes the circuit more complicated.Over the last decade,significant effort has been devoted to field-free magnetization manipulation by using SOT.In this review,we introduce the basic concepts of SOT.After that,we mainly focus on several approaches to realize the field-free deterministic SOT switching of the perpendicular magnet.The mechanisms mainly include mirror symmetry breaking,chiral symmetry breaking,exchange bias,and interlayer exchange coupling.Furthermore,we show the recent progress in the study of SOT with unconventional origin and symmetry.The final section is devoted to the industrial-level approach for potential applications of field-free SOT switching in SOT-MRAM technology. | Hao Wu Jing Zhang Baoshan Cui Seyed Armin Razavi Xiaoyu Che Quanjun Pan Di Wu Guoqiang Yu Xiufeng Han Kang L Wang | 2022 | Materials Futures2022,1,2: | 0 |