|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Chinese expert consensus on conversion therapy for hepatocellular carcinoma(2021 edition)显示文摘Recent advances in systemic and locoregional treatments for patients with unresectable or advanced hepatocellular carcinoma(HCC)have resulted in improved response rates.This has provided an opportunity for selected patients with initially unresectable HCC to achieve adequate tumor downstaging to undergo surgical resection,a‘conversion therapy’strategy.However,conversion therapy is a new approach to the treatment of HCC and its practice and treatment protocols are still being developed.Review the evidence for conversion therapy in HCC and develop consensus statements to guide clinical practice.Evidence review:Many research centers in China have accumulated significant experience implementing HCC conversion therapy.Preliminary findings and data have shown that conversion therapy represents an important strategy to maximize the survival of selected patients with intermediate stage to advanced HCC;however,there are still many urgent clinical and scientific challenges for this therapeutic strategy and its related fields.In order to summarize and learn from past experience and review current challenges,the Chinese Expert Consensus on Conversion Therapy for Hepatocellular Carcinoma(2021 Edition)was developed based on a review of preliminary experience and clinical data from Chinese and non-Chinese studies in this field and combined with recommendations for clinical practice.Sixteen consensus statements on the implementation of conversion therapy for HCC were developed.The statements generated in this review are based on a review of clinical evidence and real clinical experience and will help guide future progress in conversion therapy for patients with HCC. | Hui-Chuan Sun Jian Zhou Zheng Wang Xiufeng Liu Qing Xie Weidong Jia Ming Zhao Xinyu Bi Gong Li Xueli Bai Yuan Ji Li Xu Xiao-Dong Zhu Dousheng Bai Yajin Chen Yongjun Chen Chaoliu Dai Rongping Guo Wenzhi Guo Chunyi Hao Tao Huang Zhiyong Huang Deyu Li Gang Li Tao Li Xiangcheng Li Guangming Li Xiao Liang Jingfeng Liu Fubao Liu Shichun Lu Zheng Lu Weifu Lv Yilei Mao Guoliang Shao Yinghong Shi Tianqiang Song Guang Tan Yunqiang Tang Kaishan Tao Chidan Wan Guangyi Wang Lu Wang Shunxiang Wang Tianfu Wen Baocai Xing Bangde Xiang Sheng Yan Dinghua Yang Guowen Yin Tao Yin Zhenyu Yin Zhengping Yu Bixiang Zhang Jialin Zhang Shuijun Zhang Ti Zhang Yamin Zhang Yubao Zhang Aibin Zhang Haitao Zhao Ledu Zhou Wu Zhang Zhenyu Zhu Shukui Qin Feng Shen Xiujun Cai Gaojun Teng Jianqiang Cai Minshan Chen Qiang Li Lianxin Liu Weilin Wang Tingbo Liang Jiahong Dong Xiaoping Chen Xuehao Wang Shusen Zheng Jia Fan 无 | 2022 | Hepatobiliary Surgery and Nutrition2022，11，2： | 4 |
| 2 | Application of regional citrate anticoagulation in patients at high risk of bleeding during intermittent hemodialysis:a prospective multicenter randomized controlled trial显示文摘Objective:Safe and effective anticoagulation is essential for hemodialysis patients who are at high risk of bleeding.The purpose of this trial is to evaluate the effectiveness and safety of two-stage regional citrate anticoagulation(RCA)combined with sequential anticoagulation and standard calcium-containing dialysate in intermittent hemodialysis(IHD)treatment.Methods:Patients at high risk of bleeding who underwent IHD from September 2019 to May 2021 were prospectively enrolled in 13 blood purification centers of nephrology departments,and were randomly divided into RCA group and saline flushing group.In the RCA group,0.04 g/mL sodium citrate was infused from the start of the dialysis line during blood draining and at the venous expansion chamber.The sodium citrate was stopped after 3 h of dialysis,which was changed to sequential dialysis without anticoagulant.The hazard ratios for coagulation were according to baseline.Results:A total of 159 patients and 208 sessions were enrolled,including RCA group(80 patients,110 sessions)and saline flushing group(79 patients,98 sessions).The incidence of severe coagulation events of extracorporeal circulation in the RCA group was significantly lower than that in the saline flushing group(3.64%vs.20.41%,P<0.001).The survival time of the filter pipeline in the RCA group was significantly longer than that in the saline flushing group((238.34±9.33)min vs.(221.73±34.10)min,P<0.001).The urea clearance index(Kt/V)in the RCA group was similar to that in the saline flushing group with no statistically significant difference(1.12±0.34 vs.1.08±0.34,P=0.41).Conclusions:Compared with saline flushing,the two-stage RCA combined with a sequential anticoagulation strategy significantly reduced extracorporeal circulation clotting events and prolonged the dialysis time without serious adverse events. | Xiaoyan TANG Dezheng CHEN Ling ZHANG Ping FU Yanxia CHEN Zhou XIAO Xiangcheng XIAO Weisheng PENG Li CHENG Yanmin ZHANG Hongbo LI Kehui LI Bizhen GOU Xin WU Qian YU Lijun JIAN Zaizhi ZHU Yu WEN Cheng LIU Hen XUE Hongyu ZHANG Xin HE Bin YAN Liping ZHONG Bin HUANG Mingying MAO | 2022 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2022，23，11： | 4 |
| 3 | Oxygen vacancy enhanced biomimetic superoxide dismutase activity of CeO_(2)-Gd nanozymes显示文摘Cerium oxide-based nanozymes have recently drawn much attention in the field of biomedical and antioxidant applications,because of their unique regenerative or autocatalytic properties.Herein,we studied the biomimetic superoxide dismutase(SOD)nanozymes CeO_(2)-Gd that combines the fluorescence properties of rare earth Gd with the antioxidant properties of CeO_(2)nanoparticles,which was prepared via facile route.The structure and composition of the CeO_(2)-Gd were measured and verified by X-ray powder diffraction(XRD),Raman spectroscopy,transmission electron microscopy(TEM),energydispersive X-ray spectroscopy(EDX),and X-ray electron spectroscopy(XPS).Confocal microscopy was used to image cells.Antioxidant performance and cell viability of these nanozymes were measured in vitro using BGC-803 cell.CeO_(2)-Gd nanozymes with a higher Ce^(3+)/Ce^(4+)ratio show higher superoxide dismutase(SOD)mimetic activity.Their antioxidant activity and fluorescence properties of CeO_(2)-Gd in BGC-803 cancer cells are enhanced by oxygen vacancies generated by doping rare-earth elements Gd.This work may guide the future design of CeO_(2)-Gd-based biomimetic nanozymes for anticancer and antioxidant applications. | Xiangcheng Shi Jingjie Yang Xintong Wen Fuii Tian Changyan Li | 2021 | Journal of Rare Earths2021，39，9： | 4 |
| 4 | Pore Size Distribution and Its Quantitative Relationship with Strength of Corundum Based Castables显示文摘A series of corundum based castables with 0,2%,4%,6%,and 8% α-Al2O3 micropowders were prepared using tabular alumina aggregates (6-3,3-1 and ≤1 mm) and fines (≤0.088 and ≤0.045 mm),calcium aluminate cement,and α-Al2O3 micropowders (d50=1.754 μm) as starting materials. Cold mechanical strength and pore size distribution of the castables specimens after heat treatment at 110,1 100 and 1 500 ℃ were tested,respectively. The quantitative relationship between strength and apparent porosity,and that between strength and median pore diameter were verified by Atzeni equation. The correlation between interval of pore size and mechanical strength of specimens was also studied by means of gray relational theory. The results show that:(1) the pore size distribution of castables is strongly influenced by both micropowders filling and matrix sintering; the addition of micropowders decreases median pore diameter while the sintering process increases it; (2) when adding a constant correction term,Atzeni equation can substantially describe the quantitative relationship between median pore diameter and strength of castables specimens after heat treatment at the same temperature; the significant differences of the gray relational degree between the interval of pore size and castables strength are characterized; it is also found that for the same interval of pore size,the gray relational degree isaffected by the heat treatment temperature; the pore size interval <0.5 μm has the highest gray relational degree with the strength at 110-1 500 ℃. | FANG Binxiang ZHU Boquan LI Xiangcheng WAN Hongbo | 2010 | China's Refractories2010，19，4： | 2 |
| 5 | Sulfur-deficient Co9S8/Ni3S2 nanoflakes anchored on N-doped graphene nanotubes as high-performance electrode materials for asymmetric supercapacitors显示文摘In this paper,Co9S8/Ni3S2 nanoflakes(NFs)with sulfur deficiencies were grown in-situ on N-doped graphene nanotubes(NGNTs).They were successfully prepared through electrodeposition followed by hydrogenation treatment,which is able to act as a self-supported electrode for asymmetric supercapacitors(ASCs).Combining the defect-rich active materials with highly conductive skeletons,the hybrid electrode N-GNTs@sd-Co9S8/Ni3S2NFs show ultrahigh specific capacity of^304 mA hg^-1 and prominent rate capability(capacity retention ratio of^85%even at 100 Ag^-1),and deliver a long cycling lifespan of^1.9%capacitance loss after 10000 cycles.In addition,an ASC was constructed using the as-synthesized composite electrode as the positive electrode and active carbon(AC)as the negative electrode.The fabricated device shows a high energy density of^45.1 Wh kg^-1 at^3.4 kW kg^-1 and superior cycling stability.This work substantiates a smart strategy to fabricate novel composite electrode materials for next-generation supercapacitors by incorporating riched deficiencies into nanostructures. | ZHAO Jian SONG GuanYing YUAN XiangCheng SHEN Tong JIANG QingYan MENG ALan LIN YuSheng LI ZhenJiang LI QingDang | 2020 | Science China(Technological Sciences)2020，63，4： | 2 |
| 6 | Effect of pyrolysis temperature on preferential orientation and electrical properties of sol-gel derived lead zirconate titanate films显示文摘 | Gong Wen Li Jingfeng Chu Xiangcheng | 2004 | Journal of the European Ceramic Society2004，24，1011： | 1 |
| 7 | Simulations and analysis of a piezoelectric micro-pump 显示文摘 | Baowei Wang Xiangcheng Chu Enzhu Li etal | 2006 | Ultrasonics2006，44，1： | 1 |
| 8 | Polar codes: Encoding/decoding and rate-compatible jointly design for HARQ system显示文摘Polar coding are the first class of provable capacity-achieving coding techniques for a wide range of channels.With an ideal recursive structure and many elegant mathematical properties,polar codes are inherently implemented with low complexity encoding and decoding algorithms.Since the block length of the original polar construction is limited to powers of two,rate-compatible polar codes(RCPC)are presented to meet the flexible length/rate transmission requirements in practice.The RCPC codes are well-conditioned to combine with the hybrid automatic repeat request(HARQ)system,providing high throughput efficiency and such RCPC-HAPQ scheme is commonly used in delay-insensitive communication system.This paper first gives a survey of both the classical and state-of-the-art encoding/decoding algorithms for polar codes.Then the RCPC construction methods are discussed,including the puncturing,shortening,multi-kernel construction,etc.Finally,we investigate several RCPC-HARQ jointly design systems and discuss their encoding gain and re-transmission diversity gain. | Qiaoli Zeng Quan Zhou Xiangkun He Youming Sun Xiangcheng Li Haiqiang Chen | 2021 | Intelligent and Converged Networks2021，2，4： | 1 |
| 9 | Dependence of flame-retardant properties on density of expandable graphite filled rigid polyurethane foam显示文摘 | Bian Xiangcheng Tang Jianhua Li Zhongming | 2007 | Journal of Applied Polymer Science2007，104，5： | 1 |
| 10 | The resonance vibration properties of abimorph flexural piezoelectric ultrasonic transducer for distance measurement显示文摘 | HU Xiaobing LI Longtu CHU Xiangcheng | 2003 | Materials Science and Engineering2003，99，： | 1 |
| 11 | The design and test of a new kind of piezoelectric motor based on standing wave and multilayer显示文摘 | CHU Xiangcheng MENG Xiangyu LI Longtu | 2010 | Ferroelec- trics2010，409，1： | 1 |
| 12 | Synthesis and hydra- tion kinetics of calcium aluminate cement with micro MgA12 04 spi- nels 显示文摘 | Zhu Boquan Song Yanan Li Xiangcheng | 2015 | Mater Chem Phys2015，154，： | 1 |
| 13 | Simulations and analysis of a piezoelectric micro-pump显示文摘 | Wang Baowei Chu Xiangcheng Li Enzhu | 2006 | Ultrasonics2006，44，1： | 1 |
| 14 | Effect of ceramic bonding phases on the thermo-mechanical properties of Al 2 O 3 –C refractories显示文摘 | Boquan Zhu Yuenan Zhu Xiangcheng Li Fei Zhao | 2013 | Ceramics International2013，，6： | 1 |
| 15 | Novel phenomena in a Kundt's tube and its analysis显示文摘 | Duan Jihui Li Xiangcheng Gao Wei | 1983 | Coil Phys1983，，3： | 1 |
| 16 | Simulations and analysis of a piezoelectric micropump 显示文摘 | Wang Baowei Chu Xiangcheng Li Enzhu | 2006 | Ultrasonics2006，44，1： | 1 |
| 17 | Biomass Homogeneity Reinforced Carbon Aerogels Derived Functional Phase-Change Materials for Solar–Thermal Energy Conversion and Storage显示文摘We deviseda functional form stable compositephase-change materials(PCMs)toachieve a three-dimensional(3D)interconnectedporous carbon aerogel structure for encapsulating polyethyleneglycol(PEG).Anovelhomogeneity reinforced carbonaerogel witha well-interconnected porous structure was constructed bycombining a flexible carbonresource from biomass guar gum with hard-brittle carbonfrom polyimide,to overcome severeshrinkage andpoor mechanical performance of traditionalcarbon aerogel.Thesupportingcarbon aerogel-encapsulated PEG produced thenovel composite PCMswithgood structure stability andcomprehensive energy storage performance.Theresults showed thatthecomposite PCMsdisplayed awell-defined 3Dinterconnected structure,and theirenergy storage capacities were 171.5 and169.5 J/g,which changed onlyslightlyafter 100 thermalcycles,andthe compositescould maintainthe equilibrium temperature at50.0−58.1℃ for about 760.3 s.The thermal conductivityofthe compositescould reach0.62 W m^(−1) K^(−1),which effectively enhanced the thermalresponse rate.And thecomposite PCMs exhibited good leakage-proof performance andexcellent light–thermal conversion.The compressive strengthof thecomposite PCMscan improveupto 1.602 MPa.Results indicatethatthisstrategy canbe efficiently usedtodevelop novel composite PCMswithimproved comprehensive thermalperformance and high light–thermal conversion. | Qingfeng Zhang Tingfeng Xia Qihan Zhang Yucao Zhu Huanzhi Zhang Fen Xu Lixian Sun Xiaodong Wang Yongpeng Xia Xiangcheng Lin Hongliang Peng Pengru Huang Yongjin Zou Hailiang Chu Bin Li | 2023 | Energy & Environmental Materials2023，6，1： | 1 |
| 18 | Flame retar- dancy of whisker silicon oxide/rigid polyurethane foam com- posites with expandable graphite显示文摘 | Bian Xiangcheng Tang Jianhua Li Zhongrning | 2008 | J Appl Polym Sci2008，110，6： | 1 |
| 19 | Bio- logical characterization of chicken mesenchymal stem/pro- genitor cells from umbilical cord Wharton' s jelly 显示文摘 | BAI Chunyu LI Xiangcheng HOU Lingling | 2013 | Mol Cell Biochem2013，376，12： | 1 |
| 20 | Simulations and analysis of a piezoelectric micro-pump 显示文摘 | Wang Baowei Chu Xiangcheng Li Enzhu | 2006 | Ultrasonics2006，44，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员