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| 1 | Lifetime prediction based on Gamma processes from accelerated degradation data显示文摘Accelerated degradation test is a useful approach to predict the product lifetime at the normal use stress level, especially for highly reliable products. Two kinds of the lifetime prediction based on Gamma processes were studied. One was to predict the lifetime of the population from accelerated degradation data, and the other was to predict the lifetime of an individual by taking the accelerated degradation data as prior information. For an extensive application, the Gamma process with a time transformation and random effects was considered. A novel contribution is that a deducing method for determining the relationships between the shape and scale parameters of Gamma processes and accelerated stresses was presented. When predicting the lifetime of an individual, Bayesian inference methods were adopted to improve the prediction accuracy, in which the conjugate prior distribution and the non-conjugate prior distribution of random parameters were studied. The conjugate prior distribution only considers the random effect of the scale parameter while the non-conjugate prior distribution considers the random effects of both the scale and shape parameter. The application and usefulness of the proposed method was demonstrated by the accelerated degradation data of carbon-film resistors. | Wang Haowei Xu Tingxue Mi Qiaoli | 2015 | Chinese Journal of Aeronautics2015，28，1： | 23 |
| 2 | Data-based Fault Tolerant Control for Affine Nonlinear Systems Through Particle Swarm Optimized Neural Networks显示文摘In this paper, a data-based fault tolerant control(FTC) scheme is investigated for unknown continuous-time(CT)affine nonlinear systems with actuator faults. First, a neural network(NN) identifier based on particle swarm optimization(PSO) is constructed to model the unknown system dynamics. By utilizing the estimated system states, the particle swarm optimized critic neural network(PSOCNN) is employed to solve the Hamilton-Jacobi-Bellman equation(HJBE) more efficiently.Then, a data-based FTC scheme, which consists of the NN identifier and the fault compensator, is proposed to achieve actuator fault tolerance. The stability of the closed-loop system under actuator faults is guaranteed by the Lyapunov stability theorem. Finally, simulations are provided to demonstrate the effectiveness of the developed method. | Haowei Lin Bo Zhao Derong Liu Cesare Alippi | 2020 | IEEE/CAA Journal of Automatica Sinica2020，7，4： | 13 |
| 3 | First dark matter search results from the PandaX-Ⅰ experiment显示文摘We report on the first dark-matter(DM)search results from PandaX-I,a low threshold dual-phase xenon experiment operating at the China JinPing Underground Laboratory.In the 37-kg liquid xenon target with 17.4 live-days of exposure,no DM particle candidate event was found.This result sets a stringent limit for low-mass DM particles and disfavors the interpretation of previously-reported positive experimental results.The minimum upper limit,3.7×10-44cm2,for the spin-independent isoscalar DM-particle-nucleon scattering cross section is obtained at a DM-particle mass of 49 GeV/c2at 90%confidence level. | XIAO MengJiao XIAO Xiang ZHAO Li CAO XiGuang CHEN Xun CHEN YunHua CUI XiangYi FANG DeQing FU ChangBo GIBONI Karl L. GONG HaoWei GUO GuoDong HU Jie HUANG XingTao JI XiangDong JU YongLin LEI SiAo LI ShaoLi LIN Qing LIU HuaXuan LIU JiangLai LIU Xiang LORENZON Wolfgang MA YuGang MAO YaJun NI KaiXuan PUSHKIN Kirill REN XiangXiang SCHUBNELL Michael SHEN ManBing STEPHENSON Scott TAN AnDi TARL Greg WANG HongWei WANG JiMin WANG Meng WANG XuMing WANG Zhou WEI YueHuan WU ShiYong XIE PengWei YOU YingHui ZENG XiongHui ZHANG Hua ZHANG Tao ZHU ZhongHua | 2014 | Science China(Physics,Mechanics & Astronomy)2014，57，11： | 10 |
| 4 | Study on Dendritic Growth in Pressurized Solidification of Mg–Al Alloy Using Phase Field Simulation显示文摘A multi-grain phase field model coupled with thermodynamic calculation was adopted to describe the dendritic growth in pressurized solidification of Mg–Al alloy during squeeze casting,in which the effects of the pressure on the Gibbs free energy and chemical potential of solid and liquid phases,the solute diffusion coefficient,and the solute partition coefficient were considered. The individual effect of solute diffusion coefficient,and the Gibbs free energy on the dendritic growth was studied. With the comparison of the dendritic growth under atmospheric and elevated pressures,the effect of pressure on the microstructure evolution was discussed. The results showed that the grains are refined,the dendritic growth rate tends to increase and the secondary dendrite arms are more developed as the pressure is increased from 0.1 to 100 MPa,which showed a good agreement with the experimental results of direct squeeze casting of Mg–Al alloy. As the pressure increases,the largest dendritic growth rate can be obtained under the pressure between 200 and 250 MPa,while the growth rate decreases with a further increase of pressure. | Haowei Pan Zhiqiang Han Baicheng Liu | 2016 | Journal of Materials Science & Technology2016，32，1： | 9 |
| 5 | PandaX: a liquid xenon dark matter experiment at CJPL显示文摘PandaX is a large liquid-xenon detector experiment usable for direct dark-matter detection and 136Xe double-beta decay search.The central vessel was designed to accommodate a staged target volume increase from initially 120 kg(stage I)to 0.5 t(stage II)and eventually to a multi-ton scale.The experiment is located in the Jinping Deep-Underground Laboratory in Sichuan,China.The detector operates in dual-phase mode,allowing detection of both prompt scintillation,and ionization charge through proportional scintillation.In this paper a detailed description of the stage I detector design and performance as well as results established during the commissioning phase are presented. | CAO XiGuang CHEN Xun CHEN YunHua CUI XiangYi FANG DeQing FU ChangBo GIBONI Karl L. GONG HaoWei GUO GuoDong HE Ming HU Jie HUANG XingTao JI XiangDong JU YongLin LI ShaoLi LIN Qing LIU HuaXuan LIU JiangLai LIU Xiang LORENZON Wolfgang MA YuGang MAO YaJun NI KaiXuan PUSHKIN Kirill REN XiangXiang SCHUBNELL Michael SHEN ManBing SHI YuJie STEPHENSON Scott TAN AnDi TARLé Greg WANG HongWei WANG JiMing WANG Meng WANG XuMing WANG Zhou WEI YueHuan WU ShiYong XIAO MengJiao XIAO Xiang XIE PengWei YE Tao YOU YingHui ZEN XiongHui ZHANG Hua ZHANG Tao ZHAO HaiYing ZHAO Li ZHOU XiaoPeng ZHU ZhongHua | 2014 | Science China(Physics,Mechanics & Astronomy)2014，57，8： | 9 |
| 6 | Modeling and boundary control of a flexible marine riser coupled with internal fluid dynamics显示文摘In this paper, vibration reduction of a flexible marine riser with time-varying internal fluid is studied by using boundary control method and Lyapunov's direct method. To achieve more accurate and practical riser's dynamic behavior, the model of marine riser with time-varying internal fluid is modeled by a distributed parameter system (DPS) with partial differential equations (PDEs) and ordinary differential equations (ODEs) involving functions of space and time. The dynamic responses of riser are completely different if the time-varying internal fluid is considered. Boundary control is designed at the top boundary of the riser based on original infinite dimensionality PDEs model and Lyapunov's direct method to reduce the riser's vibrations. The uniform boundedness and closed-loop stability are proved based on the proposed boundary control. Simulation results verify the effectiveness of the proposed boundary control. | Yu LIU Haowei HUANG Hongxia GAO Xinsheng WU | 2013 | 控制理论与应用(英文版)2013，11，2： | 8 |
| 7 | Hybrid Particle Swarm Optimization Algorithm Based on Entropy Theory for Solving DAR Scheduling Problem显示文摘An efficient task-scheduling algorithm in the Digital Array Radar(DAR) is essential to ensure that it can handle a large number of requested tasks simultaneously. As a solution to this problem, in this paper, we propose an optimization model for scheduling DAR tasks using a hybrid approach. The optimization model considers the internal task structure and the DAR task-scheduling characteristic. The hybrid approach integrates a particle swarm optimization algorithm with a genetic algorithm and a heuristic task-interleaving algorithm. We introduce the chaos theory to optimize initialized particles and use entropy theory to indicate the diversity of particles and adaptively adjust the inertia weight, the crossover probability, and the mutation probability. Then, we improve both the efficiency and global exploration ability of the hybrid algorithm. In the framework of the swarm exploration algorithm, we include a heuristic task-interleaving scheduling algorithm, which not only utilizes the wait interval to transmit or receive subtasks, but also overlaps the receive intervals of different tasks. In a large-scale simulation,we demonstrate that the proposed algorithm is more robust and effective than existing algorithms. | Haowei Zhang Junwei Xie Jiaang Ge Junpeng Shi Zhaojian Zhang | 2019 | Tsinghua Science and Technology2019，24，3： | 8 |
| 8 | Synergistic effect of MXene on the flame retardancy and thermal degradation of intumescent flame retardant biodegradable poly(lactic acid)composites显示文摘The effect of Ti3C2 MXene nanosheets on the intumescent flame retardant(IFR)poly(lactic acid)(PLA)composites was investigated among a series of PLA/IFR/MXene,which were prepared by melt blending 0-2.0 wt%MXene,10.0 wt%-12.0 wt%IFR and PLA together.The results of limiting oxygen index(LOI)and vertical burning(UL-94)discover that the combination of 0.5 wt%MXene and 11.5 wt%IFR synergistically improves the fire safety of PLA to reach UL-94 V-0 rating with LOI value of 33.0%.The PLA/IFR/MXene composites perform an obvious reduction in peak of heat release rate(HRR)in cone calorimeter tests(CCTs).Furthermore,the carbon residues after CCTs were characterized by scanning electron microscope(SEM),laser Raman spectroscopy(LRS),X-ray diffraction(XRD)and X-ray photoelectron spectroscopy(XPS).It is demonstrated that both the titanium composition of the MXene structure and the characteristics of the two-dimensional material enhance the PLA/IFR/MXene composite materials’ability to produce a dense barrier layer to resist burnout during thermal degradation. | Haowei Huang Dexuan Dong Weijie Li Xinya Zhang Li Zhang Ying Chen Xinxin Sheng Xiang Lu | 2020 | Chinese Journal of Chemical Engineering2020，28，7： | 7 |
| 9 | Efficient first-principles prediction of solid stability:Towards chemical accuracy显示文摘The question of material stability is of fundamental importance to any analysis of system properties in condensed matter physics and materials science.The ability to evaluate chemical stability,i.e.,whether a stoichiometry will persist in some chemical environment,and structure selection,i.e.what crystal structure a stoichiometry will adopt,is critical to the prediction of materials synthesis,reactivity and properties.Here,we demonstrate that density functional theory,with the recently developed strongly constrained and appropriately normed(SCAN)functional,has advanced to a point where both facets of the stability problem can be reliably and efficiently predicted for main group compounds,while transition metal compounds are improved but remain a challenge.SCAN therefore offers a robust model for a significant portion of the periodic table,presenting an opportunity for the development of novel materials and the study of fine phase transformations even in largely unexplored systems with little to no experimental data. | Yubo Zhang Daniil A.Kitchaev Julia Yang Tina Chen Stephen T.Dacek Rafael A.Sarmiento-Pérez Maguel A.L.Marques Haowei Peng Gerbrand Ceder John P.Perdew Jianwei Sun | 2018 | npj Computational Materials2018，，1： | 7 |
| 10 | Adaptive control for attitude coordination of leader-following rigid spacecraft systems with inertia parameter uncertainties显示文摘This paper studies the leader-following attitude coordination problems of multiple spacecraft in the presence of inertia parameter uncertainties. To achieve attitude coordination in the situation that even the leader's attitude is only applicable to a part of the following spacecraft, a nonlinear attitude observer is proposed to obtain an accurate estimation of the leader's attitude and angular velocity for all the followers. In addition, a distributed control scheme based on noncertainty equivalence principle is presented for multiple spacecraft' attitude synchronization. With a dynamic scaling, attitude consensus can be achieved asymptotically without any information of the bounds of the uncertain inertia parameters. Furthermore, once the estimations of inertia parameters reach their ideal values, the estimation process will stop and the ideal value of inertia parameter will be held. This is a special advantage of parameter estimation method based on non-certainty equivalence. Numerical simulations are presented to demonstrate that the proposed non-certainty equivalence-based method requires smaller control toque and converges faster compared with the certainty equivalence-based method. | Xiaokui YUE Xianghong XUE Haowei WEN Jianping YUAN | 2019 | Chinese Journal of Aeronautics2019，32，3： | 6 |
| 11 | Different Transcription Profiles of SOCS-3,ob and IGF-I Genes and their Possible Correlations in Obese and Lean Pigs显示文摘猪品种在胖免职和肌肉发展能力有重要差别。然而,在这些差别后面的分子的机制仍然是 unknown.Inthis 学习,三候选人基因的表示模式,压制或表明 3 的 cytokine ( SOCS-3 ),肥胖( ob )和像胰岛素的生长因素我( IGF-I ),它涉及脂肪质的新陈代谢或肌肉开发,被分析。全部的 RNA 从 8-month-old Bamei 的背面的下的脂肪质的组织和 longissimus 被提取, Largewhite pigs.Semiquantitative reversetranscription 聚合酶链反应被用来在肌肉组织在脂肪质的组织,和 SOCS-3 和 IGF-I 基因决定 SOCS-3and ob 基因的表示层次。结果证明在脂肪质的组织, SOCS-3 的表示水平在 Bamei 是显著地更高的(肥胖) 猪比那在 Largewhite (瘦) 猪(P<0.01 ) 。然而,在肌肉组织,它在 Largewhite 猪(P<0.01 ) 比那是显著地更低的 inBamei。而且, SOCS-3 的表示断然在肌肉组织在脂肪质的组织和 IGF-I 的被相关到 ob 的。这些调查结果建议在 SOCS-3 基因表达的差别铺平在脂肪质并且肌肉纸巾,在在肌肉组织的 SOCS-3 和 IGF-I 之间的在在脂肪质的组织的 SOCS-3 和 ob 之间的关系,和那,可能贡献在肥胖、瘦的猪之间的不同胖免职和肌肉发展能力。 | Jiangwei WU Bo WANG Haowei ZHANG Taiyong YU Gongshe YANG | 2007 | Acta Biochimica et Biophysica Sinica2007，39，4： | 6 |
| 12 | High-resolution, full-color quantum dot light-emitting diode display fabricated via photolithography approach显示文摘Displays play an extremely important role in modern information society,which creates a never-ending demand for the new and better products and technologies.The latest requirements for novel display technologies focus on high resolution and high color gamut.Among emerging technologies that include organic light-emitting diode(OL ED),micro light-emiting diode(micro-LED),quantum dot light-emitting diode(QLED),laser display,holographic display and others,QLED is promising owing to its intrinsic high color gamut and the possibility to achieve high resolution with photolithography approach.However,previously demonstrated photolthography techniques suffer from reduced device performance and color Impurities in subpixels from the process.In this study,we demonstrated a sacrificial layer assisted patterming(SLAP)approach,which can be applied in conjunction with photolithography to fabricate high-resolution,full-colo quantum dot(QD)patterns.In this approach,the negative photoresist(PR)and sacrificial layer(SL)were uilized to determine the pixels for QD deposition,while at the same time the SL helps protect the QD layer and keep it intact(named PR-SL approach).To prove this method's viability for QLED display manufacture,a 500-ppi,full-color passive matrix(PM)-QLED prototype was fabricated via this process.Results show that there were no color impurities in the subpixels,and the PM-QL ED has a high color gamut of 114%National Television Standards Committee(NTSC).To the best of our knowledge,this is the first ull-olor QLED prototype with such a high resolution.We anticipate that this innovative patteming technique will open a new horizon for future display technologies and may lead to a disruptive and innovative change in display industry. | Wenhai Mei Zhenqi Zhang Aidi Zhang Dong Li Xiaoyuan Zhang Haowei Wang Zhuo Chen Yanzhao Li Xinguo Li Xiaoguang Xu | 2020 | Nano Research2020，13，9： | 6 |
| 13 | Finite sensor selection algorithm in distributed MIMO radar for joint target tracking and detection显示文摘Due to the requirement of anti-interception and the limitation of processing capability of the fusion center, the subarray selection is very important for the distributed multiple-input multiple-output(MIMO) radar system, especially in the hostile environment. In such conditions, an efficient subarray selection strategy is proposed for MIMO radar performing tasks of target tracking and detection. The goal of the proposed strategy is to minimize the worst-case predicted posterior Cramer-Rao lower bound(PCRLB) while maximizing the detection probability for a certain region. It is shown that the subarray selection problem is NP-hard, and a modified particle swarm optimization(MPSO) algorithm is developed as the solution strategy. A large number of simulations verify that the MPSO can provide close performance to the exhaustive search(ES) algorithm. Furthermore, the MPSO has the advantages of simpler structure and lower computational complexity than the multi-start local search algorithm. | ZHANG Haowei XIE Junwei GE Jiaang ZHANG Zhaojian LU Wenlong | 2020 | Journal of Systems Engineering and Electronics2020，31，2： | 5 |
| 14 | Effects of in-situ TiB_(2)particles on machinability and surface integrity in milling of TiB_(2)/2024 and TiB_(2)/7075 Al composites显示文摘In-situ ceramics particle reinforced aluminum matrix composites are favored in the aerospace industry due to excellent properties.However,the hard ceramic particles as the reinforcement phase bring challenges to machining.To study the effect of in-situ TiB_(2)particles on machinability and surface integrity of TiB_(2)/2024 composite and TiB_(2)/7075 composite,milling experiments were performed,and compared with conventional 2024 and 7075 aluminum alloys.In-situ TiB_(2)particles clustered at the grain boundaries and dispersed inside the matrix alloy grains hinder the dislocation movement of the matrix alloy.Therefore,the milling force and temperature of the composites are higher than those of the aluminum alloys due to the increase of the strength and the decrease of the plasticity.In the milling of composites,abrasive wear is the main wear form of carbide tools,due to the scratching of hard nano-TiB_(2)particles.The composites containing in-situ TiB_(2)particles have machining defects such as smearing,micro-scratches,micro-pits and tail on the machined surface.However,in-situ TiB_(2)particles impede the plastic deformation of the composites,which greatly reduces cutting edge marks on the machined surface.Therefore,under the same milling parameters,the surface roughness of TiB_(2)/2024 composite and TiB_(2)/7075 composite is much less than that of2024 and 7075 aluminum alloy respectively.Under the milling conditions of this experiment,the machined subsurface has no metamorphic layer,and the microhardness of the machined surface is almost the same as that of the material.Besides,compared with 2024 and 7075 aluminum alloy,machined surfaces of TiB_(2)/2024 composite and TiB_(2)/7075 composite both show tensile residual stress or low magnitude of compressive residual stress. | Jie CHEN Weiwei YU Zhenyu ZUO Yugang LI Dong CHEN Qinglong AN Jiwei GENG Ming CHEN Haowei WANG | 2021 | Chinese Journal of Aeronautics2021，34，6： | 5 |
| 15 | Superior anti-corrosion and self-healing bi-functional polymer composite coatings with polydopamine modified mesoporous silica/graphene oxide显示文摘In this article,graphene oxide(GO)and benzotriazole-loaded mesoporous silica nanoparticles(BTA/MSNs)are combined on micro scale through the in situ polymerization of polydopamine(PDA),preparing a selfhealing bi-functional GO(fGO)used as nano-fillers for anti-corrosion enhancement of waterborne epoxy(WEP)coatings.Scanning electronic microscopy(SEM)images show that the BTA/MSNs are uniformly distributed on the surface of high aspect ratio GO nanosheets to endow GO nanocontainer characteristics.UV-vis profiles demonstrate that fGO has p H-controlled release function.Modulus at lowest frequency is generally used for comparing the corrosion resistance of organic coatings.Modulus at lowest frequency(1.42×10^(5)Ωcm^(2))after 30 days immersion in 3.5 wt.%Na Cl solution revealed 2 orders of magnitude higher that of blank WEP(1.17×10^(7)Ωcm^(2)).With artificial cracks on its coatings,fGO/WEP had no obvious rust compared with blank WEP after 240 h of immersion.We anticipate that self-healing and physical barrier bi-functional nanocontainers improve the traditional anticorrosion coating efficiency with better,longer-lasting performance for shipping,oil drilling or bridge maintenance. | Yanqi Ma Haowei Huang Hongda Zhou Michael Graham James Smith Xinxin Sheng Ying Chen Li Zhang Xinya Zhang Elena Shchukina Dmitry Shchukin | 2021 | Journal of Materials Science & Technology2021，，36： | 4 |
| 16 | Mitotic motor CENP-E cooperates with PRC1 in temporal control of central spindle assembly显示文摘Error-free cell division depends on the accurate assembly of the spindle midzone from dynamic spindle microtubules to ensure chromatid segregation during metaphase-anaphase transition.However,the mechanism underlying the key transition from the mitotic spindle to central spindle before anaphase onset remains elusive.Given the prevalence of chromosome instability phenotype in gastric tumorigenesis,we developed a strategy to model context-dependent cell division using a combination of light sheet microscope and 3D gastric organoids.Light sheet microscopic image analyses of 3D organoids showed that CENP-E inhibited cells undergoing aberrant metaphase-anaphase transition and exhibiting chromosome segregation errors during mitosis.Highresolution real-time imaging analyses of 2D cell culture revealed that CENP-E inhibited cells undergoing central spindle splitting and chromosome instability phenotype.Using biotinylated syntelin as an affinity matrix,we found that CENP-E forms a complex with PRC1 in mitotic cells.Chemical inhibition of CENP-E in metaphase by syntelin prevented accurate central spindle assembly by perturbing temporal assembly of PRC1 to the midzone.Thus,CENP-E-mediated PRC1 assembly to the central spindle constitutes a temporal switch to organize dynamic kinetochore microtubules into stable midzone arrays.These findings reveal a previously uncharacterized role of CENP-E in temporal control of central spindle assembly.Since CENP-E is absent from yeast,we reasoned that metazoans evolved an elaborate central spindle organization machinery to ensure accurate sister chromatid segregation during anaphase and cytokinesis. | Xu Liu Leilei Xu Junying Li Phil Y.Yao Wanjuan Wang Hazrat Ismail Haowei Wang Bryce Liao Zhihong Yang Tarsha Ward Ke Ruan Jianchun Zhang Quan Wu Ping He Xia Ding Dongmei Wang Chuanhai Fu Zhen Dou Feng Yan Wenwen Wang Xing Liu Xuebiao Yao | 2020 | Journal of Molecular Cell Biology2020，12，8： | 3 |
| 17 | Pulse interleaving scheduling algorithm for digital array radar显示文摘An online pulse interleaving scheduling algorithm is proposed for a solution to the task scheduling problem in the digital array radar(DAR). The full DAR task structure is explicitly considered in a way that the waiting duration is able to be utilized to transmit or receive subtasks, namely the pulse interleaving,as well as the receiving durations of different tasks are able to be overlapped. The algorithm decomposes the pulse interleaving scheduling analysis into the time constraint check and the energy constraint check, and schedules online all kinds of tasks that are able to be interleaved. Thereby the waiting duration and the receiving duration in the DAR task are both fully utilized. The simulation results verify the performance improvement and the high efficiency of the proposed algorithm compared with the existing ones. | ZHANG Haowei XIE Junwei ZHANG Zhaojian ZONG Binfeng SHENG Chuan | 2018 | Journal of Systems Engineering and Electronics2018，29，1： | 3 |
| 18 | The influence of nanosized precipitates on Portevin-Le Chatelier bands and surface roughness in AlMgScZr alloy显示文摘The influence of different precipitate-dislocation interactions,namely dislocation shearing and bypassing mechanisms,on PLC bands and the resultant surface roughness in AlMgScZr alloy was investigated.Three-dimensional surface roughness was quantitatively measured by confocal microscopy.We find that the introduction of shearable precipitates increases the stress amplitude,decreases the PLC bands number and surface roughness.However,the stress amplitude decreases,the PLC bands number and surface roughness increase with shearable precipitates turning to nonshearable precipitates.By analyzing the precipitation strengthening mechanisms quantitatively,the influence of precipitates on PLC bands and the resultant surface roughness was explored.Furthermore,our study demonstrates that the shearable precipitates can decrease the surface roughness by decreasing the number of PLC bands,which is instructive for designing structural materials with desirable mechanical property and surface quality. | Yaoxiang Duan Han Chen Zhe Chen Lei Wang Mingliang Wang Jun Liu Fengguo Zhang Haowei Wang | 2021 | Journal of Materials Science & Technology2021，，28： | 3 |
| 19 | Broadband quasi-phase matching in a MgO:PPLN thin film显示文摘Future quantum information networks operated on telecom channels require qubit transfer between different wavelengths while preserving quantum coherence and entanglement. Qubit transfer is a nonlinear optical process,but currently the types of atoms used for quantum information processing and storage are limited by the narrow bandwidth of upconversion available. Here we present the first experimental demonstration of broadband and high-efficiency quasi-phase matching second-harmonic generation(SHG) in a chip-scale periodically poled lithium niobate thin film. We achieve a large bandwidth of up to 2 THz for SHG by satisfying quasi-phase matching and group-velocity matching simultaneously. Furthermore, by changing the film thickness, the central wavelength of the quasi-phase matching SHG bandwidth can be modulated from 2.70 μm to 1.44 μm. The reconfigurable quasi-phase matching lithium niobate thin film provides a significant on-chip integrated platform for photonics and quantum optics. | LICHENG GE YUPING CHEN HAOWEI JIANG GUANGZHEN LI BING ZHU YI'AN LIU XIANFENG CHEN | 2018 | Photonics Research2018，6，10： | 3 |
| 20 | CaMKIIα-driven,phosphatase-checked postsynaptic plasticity via phase separation显示文摘Ca^(2+)/calmodulin-dependent kinase Ila(CaMKIla)is essential for synaptic plasticity and learning by decoding synaptic Ca^(2+)oscillations.Despite decades of extensive research,new mechanisms underlying CaMKIIa's function in synapses are still being discovered.Here,we discover that Shank3 is a specific binding partner for autoinhibited CaMKIla.We demonstrate that Shank3 and GluN2B,via combined actions of Ca^(2+)and phosphatases,reciprocally bind to CaMKIla.Under basal condition,CaMKIla is recruited to the Shank3 subcompartment of postsynaptic density(PSD)via phase separation.Rise of Ca^(2+)concentration induces GluN2Bmediated recruitment of active CaMKIla and formation of the CaMKIIa/GluN2B/PSD-95 condensates,which are autonomously dispersed upon Ca^(2+)removal.Protein phosphatases control the Ca^(2+)-dependent shuttling of CaMKIla between the two PSD subcompartme nts and PSD condensate formation.Activation of CaMKIla further enlarges the PSD assembly and in duces structural LTP.Thus,Ca^(2+)-induced and phosphatase-checked shuttling of CaMKIla between distinct PSD nano-domains can regulate phase separation-mediated PSD assembly and synaptic plasticity. | Qixu Caic Menglong Zeng Xiandeng Wu Haowei Wu Yumeng Zhan Ruijun Tian Mingjie Zhang | 2021 | Cell Research2021，31，1： | 3 |
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