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| 1 | Genome Analysis of the Ancient Tracheophyte Selaginella tama#scina Reveals Evolutionary Features Relevant to the Acquisition of Desiccation Tolerance显示文摘 | Zhichao Xu Tianyi Xin Dorothea Bartels Ying Li Wei Gu Hui Yao Sai Liu Haoying Yu Xiangdong Pu Jianguo Zhou Jiang Xu Caicai xi Hetian Lei Jingyuan song Shilin Chen | 2018 | Molecular Plant2018，11，7： | 20 |
| 2 | Longitudinal two-dimensional strain rate imaging: a potential approach to predict the response to cardiac resynchronization therapy显示文摘 | Haoying Shi Xianhong Shu Fang Wang Jie Cui Haozhu Chen Baogui Sun Shaowen Liu | 2009 | The International Journal of Cardiovascular Imaging2009，，： | 1 |
| 3 | Photo-crosslinking polymerization to prepare polyanhydride/needle-like hydroxyapatite biodegradable nanocomposite for orthopedic application显示文摘 | Li Haoying Chen Yunfa Xie Yusheng | 2003 | Materials Letters2003，57，： | 1 |
| 4 | Flow field analysis and response surface research on the rotor in dry powder inhaler显示文摘 | ZHAO Chen LI Haoying SHI Hongshi | 2014 | Advanced Materials Research2014，983，： | 1 |
| 5 | Preparation of Organic–Inorganic Multifunctional Nanocomposite Coating via Sol-Gel Routes显示文摘 | Haoying Li Yunfa Chen Chengxiang Ruan Weimin Gao Yusheng Xie | 2001 | Journal of Nanoparticle Research (-)2001，，2： | 1 |
| 6 | Surface air temperature changes over the Tibetan Plateau:Historical evaluation and future projection based on CMIP6 models显示文摘With its amplification simultaneously emerging in cryospheric regions,especially in the Tibetan Plateau,global warming is undoubtedly occurring.In this study,we utilized 28 global climate models to assess model performance regarding surface air temperature over the Tibetan Plateau from 1961 to 2014,reported spatiotemporal variability in surface air temperature in the future under four scenarios(SSP1-2.6,SSP2-4.5,SSP3-7.0,and SSP5-8.5),and further quantified the timing of warming levels(1.5,2,and 3℃)in the region.The results show that the multimodel ensemble means depicted the spatiotemporal patterns of surface air temperature for the past decades well,although with differences across individual models.The projected surface air temperature,by 2099,would warm by 1.9,3.2,5.2,and 6.3℃relative to the reference period(1981–2010),with increasing rates of 0.11,0.31,0.53,and 0.70℃/decade under the SSP1-2.6,SSP2-4.5,SSP3-7.0,and SSP5-8.5 scenarios for the period 2015–2099,respectively.Compared with the preindustrial periods(1850–1900),the mean annual surface air temperature over the Tibetan Plateau has hit the 1.5℃threshold and will break 2℃in the next decade,but there is still a chance to limit the temperature below 3℃in this century.Our study provides a new understanding of climate warming in high mountain areas and implies the urgent need to achieve carbon neutrality. | Rui Chen Haoying Li Xuejia Wang Xiaohua Gou Meixue Yang Guoning Wan | 2022 | Geoscience Frontiers2022，13，6： | 0 |
| 7 | Preparation of Ag-MnFe204-bentonite Magnetic Composite for Pb(II)/Cd(II) Adsorption Removal and Bacterial Inactivation in Wastewater显示文摘 | LI Qin ZHAO Yongsheng QU Dan WANG Haoying CHEN Jin ZHOU Rui | 2018 | Chemical Research in Chinese Universities2018，34，5： | 0 |
| 8 | A Cascade Targeted and Activatable NIR-ⅡNanoprobe for Highly Sensitive Detection of Acute Myeloid Leukemia in an Orthotopic Model显示文摘Acute myeloid leukemia(AML)remains a significant concern in modern medicine.Early diagnosis is the key to improving the therapeutic effects of AML.In the present work,a cascade-targeted and activatable NIR-Ⅱ nanoprobe(Ald&A1094@Ag_(2)S)was developed for early detection of AML in an orthotopic model.Upon intravenous injection,Ald&A1094@Ag_(2)S effectively accumulated in bone tissue due to its high affinity for alendronate(Ald)to the bone.Thereafter,the AML microenvironment allowed for the membrane-penetrating peptide TAT(cell‐penetrating peptide(CGRRRQRRKKRG))to be exposed via pH-sensitive hydrazone bond-mediated detaching of bone-targeted ligands,resulting in efficient internalization of nanoprobes in HL60 cells.Endogenous peroxynitrite(ONOO–)in HL60 cells further activated NIR-Ⅱ fluorescence of Ag_(2)S QDs via A1094 oxidation,thereby inhibiting fluorescence resonance energy transfer(FRET).Such a unique cascade-targeted and activatable strategy enables the nanoprobes to only light up the AML lesion region in the bone marrow with negligible background effects,which holds great potential for clinical applications in the future. | Xiaohu Yang Xinyi An Sisi Ling Haoying Huang Yejun Zhang Guangcun Chen Chunyan Li &Qiangbin Wang | 2021 | CCS Chemistry2021，3，3： | 0 |
| 9 | PET imaging on neurofunctional changes after optogenetic stimulation in a rat model of panic disorder显示文摘Panic disorder (PD) is an acute paroxysmal anxiety disorder with poorly understood pathophysiology. The dorsal periaqueductal gray (dPAG) is involved in the genesis of PD. However, the downstream neurofunctional changes of the dPAG during panic attacks have yet to be evaluated in vivo. In this study, optogenetic stimulation to the dPAG was performed to induce panic-like behaviors, and in vivo positron emission tomography (PET) imaging with ,8F-flurodeoxyglucose (18F-FDG) was conducted to evaluate neurofunctional changes before and after the optogenetic stimulation. Compared with the baseline, post-optogenetic stimulation PET imaging demonstrated that the glucose metabolism significantly increased (P < 0.001) in dPAG, the cuneiform nucleus, the cerebellar lobule, the cingulate cortex, the alveus of the hippocampus, the primary visual cortex, the septohypothalamic nucleus, and the retrosplenial granular cortex but significantly decreased (P < 0.001) in the basal ganglia, the frontal cortex, the forceps minor corpus callosum, the primary somatosensory cortex, the primary motor cortex, the secondary visual cortex, and the dorsal lateral geniculate nucleus. Taken together, these data indicated that in vivo PET imaging can successfully detect downstream neurofunctional changes involved in the panic attacks after optogenetic stimulation to the dPAG. | Xiao He Chentao Jin Mindi Ma Rui Zhou Shuang Wu Haoying Huang Yuting Li Qiaozhen Chen Mingrong Zhang Hong Zhang Mei Tian | 2019 | Frontiers of Medicine2019，13，5： | 0 |
| 10 | NITROGEN USE AND MANAGEMENT IN ORCHARDS AND VEGETABLE FIELDS IN CHINA: CHALLENGES AND SOLUTIONS显示文摘China is the largest producer and consumer of fruits and vegetables in the world.Although the annual planting areas of orchards and vegetable fields(OVF)account for 20%of total croplands,they consume more than 30%of the mineral nitrogen fertilizers in China and have become hotspots of reactive N emissions.Excess N fertilization has not only reduced the N use efficiency(NUE)and quality of grown fruits and vegetables but has also led to soil acidification,biodiversity loss and climate change.Studies using 15N labeling analysis showed that the recovery rate of N fertilizer in OVFs was only 16.6%,and a high proportion of fertilizer N resided in soils(48.3%)or was lost to the environment(35.1%).Nitrate accumulation in the soil of OVFs is the main fate of N fertilizer in northern China,which threatens groundwater quality,while leaching and denitrification are the important N fates of N fertilizer in southern China.Therefore,taking different measures to reduce N loss and increase NUE based on the main pathways of N loss in the various regions is urgent,including rational N fertilization,substituting mineral N fertilizers with organic fertilizers,fertigation,and adding mineral N fertilizers with urease inhibitors and nitrification inhibitors. | Xueqiang ZHU Peng ZHOU Peng MIAO Haoying WANG Xinlu BAI Zhujun CHEN Jianbin ZHOU | 2022 | Frontiers of Agricultural Science and Engineering2022，9，3： | 0 |
| 11 | Flow control of double bypass variable cycle engine in modal transition显示文摘To study the change mechanism and the control of the variable cycle engine in the process of modal transition,a variable cycle engine model based on component level characteristics is established.The two-dimensional CFD technology is used to simulate the influence of mode selection valve rotation on the engine flow field,which improves the accuracy of the model.Furthermore,the constant flow control plan is proposed in the modal transition process to reduce the engine installed drag.The constant flow control plan adopts the augmentation linear quadratic regulator control method.Simulation results indicate that the control method is able to effectively control the bypass ratio and demand flow of the variable cycle engine,and make the engine transform smoothly,which ensures the stable operation of the engine in modal transition and the constant demand flow of the engine. | Haoying CHEN Changpeng CAI Jiayi LUO Haibo ZHANG | 2022 | Chinese Journal of Aeronautics2022，35，10： | 0 |
| 12 | Evaluation and prediction of the status of COVID-19 epidemic prevention and control based on the SEIR+CAQ model显示文摘This paper analyzes the spread of the COVID-19 epidemic in China,establishes a SEIR^(+CAQ)epidemiologic model that classifies the diagnosed population into asymptomatic,mild,and severe,and considers the condition of an isolated population.First of all,we theoretically analyzed the key problems of the disease-free equilibrium,stability,and basic reproduction number of the model.Then,combined with the actual data,the development trend of the epidemic situation is simulated and compared,and the influence of some important parameters is discussed in the model evaluation part.Finally,based on the theoretical analysis and numerical simulation results,we forecast the future development of the COVID-19 epidemic and put forward some reasonable scientific suggestions for the government to formulate a future epidemic prevention policy. | Xingzhi Chen Baodan Tian Feixiang Huang Daiwen Wang Linyan Fu Haoying Xu | 2021 | International Journal of Modeling, Simulation, and Scientific Computing2021，12，3： | 0 |
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