|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Low rates of adherence for tumor necrosis factor-α inhibitors in Crohn's disease and rheumatoid arthritis: Results of a systematic review显示文摘AIM:To investigate adherence rates in tumor necrosis factor-α (TNF-α)-inhibitors in Crohn's disease (CD) and rheumatoid arthritis (RA) by systematic review of medical literature. METHODS:A structured search of PubMed between 2001 and 2011 was conducted to identify publications that assessed treatment with TNF-α inhibitors providing data about adherence in CD and RA. Therapeutic agents of interest where adalimumab, infliximab and etanercept, since these are most commonly used for both diseases. Studies assessing only drug survival or continuation rates were excluded. Data describing adherence with TNF-α inhibitors were extracted for each selected study. Given the large variation between definitions of measurement of adherence, the definitions as used by the authors where used in our calculations. Data were tabulated and also presented descriptively. Sample size-weighted pooled proportions of patients adherent to therapy and their 95%CI were calculated.To compare adherence between infliximab, adalimumab and etanercept, the adherence rates where graphed alongside two axes. Possible determinants of adherence were extracted from the selected studies and tabulated using the presented OR. RESULTS:Three studies on CD and three on RA were identified, involving a total of 8147 patients (953 CD and 7194 RA). We identified considerable variation in the definitions and methodologies of measuring adherence between studies. The calculated overall sample size-weighted pooled proportion for adherence to TNF-α inhibitors in CD was 70% (95%CI:67%-73%) and 59% in RA (95%CI:58%-60%). In CD the adherence rate for infliximab (72%) was highercompared to adalimumab (55%), with a relative risk of 1.61 (95%CI:1.27-2.03), whereas in RA adherence for adalimumab (67%) was higher compared to both infliximab (48%) and etanercept (59%), with a relative risk of 1.41 (95%CI:1.3-1.52) and 1.13 (95%CI:1.10-1.18) respectively. In comparative studies in RA adherence to infliximab was better than etanercept and etanercept did better than adalimumab. In three studies, the most consistent factor associated with lower adherence was female gender. Results for age, immunomodulator use and prior TNF-α inhibitors use were conflicting. CONCLUSION:One-third of both CD and RA patients treated with TNF-α inhibitors are non-adherent. Female gender was consistently identified as a negative determinant of adherence. | Herma H Fidder Maartje MJ Singendonk Mike van der Have Bas Oldenburg Martijn GH van Oijen | 2013 | World Journal of Gastroenterology2013，19，27： | 2 |
| 2 | The robotic applica- tions are more economically feasible than the conventional systems显示文摘 | Pedersen S M Fountas S Have H | 2006 | Precision Agric2006，，7： | 1 |
| 3 | Averse events after protamine administration following cardiopulmonary bypass ininfants and children显示文摘 | SEIFERT H A JOBES D R TEN HAVE T | 2003 | Anesth Analg2003，97，2： | 1 |
| 4 | Interactive technology assessment and wide reflective equilibrium显示文摘 | Reuzel R P van der Wilt G J ten Have H A | 2001 | J Med Philos2001，26，3： | 1 |
| 5 | Heat extraction from a flow reversal reactor in lean methane combustion 显示文摘 | Sapoundjiev H Poirier M Haves R E | 2005 | Chemical Engineering Research and Design2005，83，2： | 1 |
| 6 | Haplodiploidy and the evolution of the social insects显示文摘 | TRIVERS R L HAVE H | 1976 | Science1976，191，： | 1 |
| 7 | Ethical perspective on health technology assessment 显示文摘 | TEN HAVE H | 2004 | International Journal of Technology Assessment in Health Care2004，20，1： | 1 |
| 8 | Dementia and depression in old age : psychophysiological aspects 显示文摘 | Have G Kolbeinson H Petursson H | 1991 | Acta Psychiatr Scand1991，83，5： | 1 |
| 9 | Genomic analysis of the necrotrophic fungal pathogens Sclerotinia sclerotiorum and Botrytis cinerea显示文摘 | Amselem J Cuomo C A van Kan J A Viaud M Benito E P Couloux A Coutinho P M de Vries R P Dyer PS Fillinger S Fournier E Gout L Hahn M Kohn L Lapalu N Plummer K M Pradier J M Quévillon E Sharon A Simon A ten Have A Tudzynski B Tudzynski P Wincker P Andrew M Anthouard V Beever R E Beffa R Benoit I Bouzid O Brault B Chen Z Choquer M Collémare J Cotton P Danchin E G Da Silva C Gautier A Giraud C Giraud T Gonzalez C Grossetete S Güldener U Henrissat B Howlett B J Kodira C Kretschmer M Lappartient A Leroch M Levis C Mauceli E Neuvéglise C Oeser B Pearson M Poulain J Poussereau N Quesneville H Rascle C Schumacher J Ségurens B Sexton A Silva E Sirven C Soanes D M Talbot N J Templeton M Yandava C Yarden O Zeng Q Rollins J A Lebrun M H Dickman M | 2011 | PLoS Genetics2011，7，10： | 1 |
| 10 | The robotic applications are more economically feasible than the conventional systems 显示文摘 | Pedersen S M Fountas S Have H | 2006 | Precision Agric2006，7，： | 1 |
| 11 | Demonstration of antibodies against bovine leukemia virus (BLV) by blocking ELISA using bovine polyclonal anti-BLV immunoglobulin 显示文摘 | Have P Rikke H | 1991 | Vet Microbiol1991，27，： | 1 |
| 12 | Homozygous deletions inactivate DCC, but not MADH4/DPC4/SMAD4, in a subset of pancreatic and biliary cancers 显示文摘 | Werner H Song JJ Have M | 2000 | Genes Chromosomes Cancer2000，27，4： | 1 |
| 13 | Informed consent in biomedical studies on aging:survey of four journals显示文摘 | Rikkert M G O ten Have H A Hoefnagels W H | 1996 | BMJ1996，313，： | 1 |
| 14 | The robotic applications are more economically feasible than the conventional systems 显示文摘 | Pedersen S M Fountas S Have H | 2006 | Precision Agric2006，，7： | 1 |
| 15 | Reducing Suicidal Ideation and Depression in Older Primary Care Patients: 24-Month Outcomes of the PROSPECT Study显示文摘 | Alexopoulos George S Reynolds Charles F Bruce Martha L Katz Ira R Raue Patrick J Mulsant Benoit H Oslin David W Have Thomas Ten | 2009 | The American Journal of Psychiatry2009，，： | 1 |
| 16 | Evolution and functional diversification of the small heat shock protein/alpha-crystallin family in higher plants显示文摘 | Bondino H G Valle E M Ten Have A | 2012 | Planta2012，235，6： | 1 |
| 17 | Accurate coregistration between ultra-high-resolution micro-SPECT and circular cone-beam micro-CT scanners显示文摘 | Ji C van der Have F Gratama van Andel H | | 0，，： | 1 |
| 18 | 显示文摘 | Willekens H Vancamp W Lnze D Ozne sulfur dioxide and ozone ultraviolet-B have similar effect on mRNA accumulation of antioxidant genes in Nicotiana plumbaginifolia L | 1994 | Plant Physiol1994，106，： | 1 |
| 19 | Lung function and bronchial reactivity in asthmatics during exposure to volatile organic compounds 显示文摘 | Dahl R Molhave L | 1991 | Am Rev Respir Dis1991，143，4： | 1 |
| 20 | Nitrification limitation in animal slurries at high temperatures显示文摘 | Willers H C Derikx P J L Have P J W | 1998 | Bioresource Technology1998，64，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员